Kyu Back Lee
Affiliation: Korea University
Kim J, Park B, Kim S, Lee D, Lee G, Kim D, et al
. Nanotopographical Regulation of Pancreatic Islet-like Cluster Formation from Human Pluripotent Stem Cells using a Gradient-Pattern Chip. Acta Biomater. 2018;: pubmed publisher
..Our findings suggest gradient nanopatterned chip provides a powerful tool to generate specific functional cell types of a high purity for potential uses in cell therapy development. ..
Kim D, Cui L, Seo H, Joo H, Choi S, Lim D, et al
. Fabrication of Gradient Nanopattern by Thermal Nanoimprinting Technique and Screening of the Response of Human Endothelial Colony-forming Cells. J Vis Exp. 2018;: pubmed publisher
..In this protocol, we describe the step-by-step procedure of fabricating gradient nanopattern plates for cell engineering, techniques of cultivating hECFCs from human peripheral blood, and culturing hECFCs on nanopattern plates. ..
Hwang J, Lee D, Byun M, Kim A, Kim K, Park J, et al
. Nanotopological plate stimulates osteogenic differentiation through TAZ activation. Sci Rep. 2017;7:3632 pubmed publisher
..Taken together, these results indicate that nanotopology regulates cell differentiation through TAZ activation. ..
Cui L, Joo H, Kim D, Seo H, Kim J, Choi S, et al
. Manipulation of the response of human endothelial colony-forming cells by focal adhesion assembly using gradient nanopattern plates. Acta Biomater. 2018;65:272-282 pubmed publisher
..Furthermore, we only modulate the nanopillar size to increase ROCK expression can be an attractive method for modulating the cytoskeletal integrity and focal adhesion of hECFCs. ..