Hee Gu Lee
Affiliation: Korea Research Institute of Bioscience and Biotechnology
Lee J, Yoon S, Lee S, Lee M, Jung H, Kim T, et al
. Ginsenoside Rg3 ameliorated HFD-induced hepatic steatosis through downregulation of STAT5-PPAR?. J Endocrinol. 2017;235:223-235 pubmed publisher
..This is the first report of evidence that obesity-induced insulin resistance and lipotoxicity can be treated with ginsenoside Rg3, which acts though the STAT5-PPAR gamma pathway in vivo and in vitro...
Park S, Lee S, Cho H, Kim J, Yoon H, Lee K, et al
. Epsilon-Globin HBE1 Enhances Radiotherapy Resistance by Down-Regulating BCL11A in Colorectal Cancer Cells. Cancers (Basel). 2019;11: pubmed publisher
..Collectively, these observations indicate that the expression of HBE1 during radiotherapy might potentiate the survival of radiation-exposed colorectal cancer cells. ..
Cho H, Kim J, Lee S, Hwang Y, Park S, Kim B, et al
. Protein phosphatase 1B dephosphorylates Rho guanine nucleotide dissociation inhibitor 1 and suppresses cancer cell migration and invasion. Cancer Lett. 2018;417:141-151 pubmed publisher
..Collectively, these results indicate that PPM1B negatively regulates cancer cell motility and invasiveness through dephosphorylating RhoGDI1. ..
Kang J, Kang Y, Oh B, Uhm T, Park S, Kim T, et al
. Tescalcin expression contributes to invasive and metastatic activity in colorectal cancer. Tumour Biol. 2016;37:13843-13853 pubmed
..These results implicate TESC as a metastatic mediator and provide a biological rationale for the adverse prognosis associated with elevated TESC expression in human CRC. ..