Su Nam Kim

Summary

Affiliation: Korea Institute of Science and Technology
Country: Korea

Publications

  1. Jegal J, Park N, Kim T, Choi S, Lee S, Hang J, et al. Effect of Topically Applied Wikstroemia dolichantha Diels on the Development of Atopic Dermatitis-Like Skin Symptoms in Mice. Nutrients. 2019;11: pubmed publisher
  2. Kim W, Lee W, Jung Y, Jang H, Kim Y, Kim S. PPARβ/δ agonist GW501516 inhibits TNFα-induced repression of adiponectin and insulin receptor in 3T3-L1 adipocytes. Biochem Biophys Res Commun. 2019;510:621-628 pubmed publisher
    ..Therefore, PPARδ may be a promising therapeutic target for treatment of insulin resistance in patients with T2DM. ..
  3. Jegal J, Park N, Jo B, Bong S, Jegal H, Yang M, et al. Anti-Atopic Properties of Gracillin Isolated from Dioscorea quinqueloba on 2,4-Dinitrochlorobenzene-Induced Skin Lesions in Mice. Nutrients. 2018;10: pubmed publisher
    ..Our results suggest gracillin is a potential candidate for the prevention and treatment of AD and other inflammatory skin disorders. ..
  4. Choi Y, Jung Y, Kim S. Identification of Eupatilin from Artemisia argyi as a Selective PPARα Agonist Using Affinity Selection Ultrafiltration LC-MS. Molecules. 2015;20:13753-63 pubmed publisher
    ..Thus, ultrafiltration LC-MS is a suitable assay for the identification of PPAR ligands in complex matrixes such as extracts of dietary foods and botanicals. ..
  5. Jo B, Park N, Jegal J, Choi S, Lee S, Jin H, et al. A new flavonoid from Stellera chamaejasme L., stechamone, alleviated 2,4-dinitrochlorobenzene-induced atopic dermatitis-like skin lesions in a murine model. Int Immunopharmacol. 2018;59:113-119 pubmed publisher
    ..The results obtained suggest stechamone is a potential anti-atopic agent and treatment for skin inflammatory diseases. ..
  6. Park J, Kwak J, Kang K, Jung E, Lee D, Lee S, et al. Wound healing effects of deoxyshikonin isolated from Jawoongo: In vitro and in vivo studies. J Ethnopharmacol. 2017;199:128-137 pubmed publisher
    ..Collectively, these data suggest that deoxyshikonin in Jawoongo must be an active compound for may be wound healing. ..
  7. Jung Y, Kim J, Park N, Bong S, Lee S, Jegal H, et al. Eupatilin, an activator of PPARα, inhibits the development of oxazolone-induced atopic dermatitis symptoms in Balb/c mice. Biochem Biophys Res Commun. 2018;496:508-514 pubmed publisher
    ..Taken together, our data suggest that eupatilin is a potential candidate for the treatment of AD. ..
  8. Kim S, Lee W, Bae G, Kim Y. Anti-diabetic and hypolipidemic effects of Sargassum yezoense in db/db mice. Biochem Biophys Res Commun. 2012;424:675-80 pubmed publisher
    ..Altogether, our data suggest that SY would be a potential therapeutic agent against type 2 diabetes and related metabolic disorders by ameliorating the glucose and lipid metabolism. ..
  9. Jung Y, Kim J, Choi Y, Lee S, Kang K, Kim Y, et al. Eupatilin with PPAR? agonistic effects inhibits TNF?-induced MMP signaling in HaCaT cells. Biochem Biophys Res Commun. 2017;493:220-226 pubmed publisher
    ..Taken together, our data suggest that eupatilin inhibits TNF?-induced MMP-2/-9 expression by suppressing NF-?B and MAPK?AP-1 pathways via PPAR?. Our findings suggest the usefulness of eupatilin for preventing skin aging. ..

More Information

Publications15

  1. Jung Y, Cao Y, Paudel S, Yoon G, Cheon S, Bae G, et al. Antidiabetic effect of SN158 through PPAR?/? dual activation in ob/ob mice. Chem Biol Interact. 2017;268:24-30 pubmed publisher
    ..These results suggest that SN158 can be useful as a potential therapeutic agent against type 2 diabetes and related metabolic disorders by alleviating glucose and lipid abnormalities. ..
  2. Lee S, Lee D, Kim J, Um B, Sung S, Jeong L, et al. Pectolinarigenin, an aglycone of pectolinarin, has more potent inhibitory activities on melanogenesis than pectolinarin. Biochem Biophys Res Commun. 2017;493:765-772 pubmed publisher
    ..setidens water extract, several component conversion methods were studied. Consequently, we identified that microwave irradiation under 1% acetic acid was an optimum sugar elimination method. ..
  3. Jegal J, Park N, Bong S, Jegal H, Kim S, Yang M. Dioscorea quinqueloba Ameliorates Oxazolone- and 2,4-Dinitrochlorobenzene-induced Atopic Dermatitis Symptoms in Murine Models. Nutrients. 2017;9: pubmed publisher
    ..Therapeutic applications with D. quinqueloba might be useful in the treatment of AD and related inflammatory skin diseases. ..
  4. Jeon H, Kim D, Nho Y, Park J, Kim S, Choi E. A Mixture of Extracts of Kochia scoparia and Rosa multiflora with PPAR ?/? Dual Agonistic Effects Prevents Photoaging in Hairless Mice. Int J Mol Sci. 2016;17: pubmed
    ..KR decreased the expression of epidermal interleukin (IL)-1?. Collectively, KR showed possible utility as a therapeutic agent for photoaging skin, with few epidermal side effects such as epidermal hyperplasia or poor differentiation. ..
  5. Park J, Lee Y, Lee D, Yoo J, Shin M, Yamabe N, et al. Abietic acid isolated from pine resin (Resina Pini) enhances angiogenesis in HUVECs and accelerates cutaneous wound healing in mice. J Ethnopharmacol. 2017;203:279-287 pubmed publisher
    ..The current data indicate that abietic acid treatment elevated cell migration and tube formation in HUVECs by the activation of ERK and p38 MAPKs. We suggest that abietic acid can be developed as a wound-healing agent. ..
  6. Lee S, Park N, Bong S, Jegal J, Park S, Kim S, et al. Ameliorative effects of Juniperus rigida fruit on oxazolone- and 2,4-dinitrochlorobenzene-induced atopic dermatitis in mice. J Ethnopharmacol. 2018;214:160-167 pubmed publisher
    ..Therapeutic attempts with J. rigida fruit and its active components might be useful in treating AD and related skin inflammatory diseases. ..