Jung Hoe Kim

Summary

Affiliation: Korea Advanced Institute of Science and Technology
Country: Korea

Publications

  1. pmc Xylitol production is increased by expression of codon-optimized Neurospora crassa xylose reductase gene in Candida tropicalis
    Woo Young Jeon
    Department of Biological Sciences, Korea Advanced Institute of Science and Technology, 373 1, Guseong Dong, Yuseong Gu, Daejeon, 305 701, Korea
    Bioprocess Biosyst Eng 35:191-8. 2012
  2. doi request reprint N-glycosylation status of beta-haptoglobin in sera of patients with colon cancer, chronic inflammatory diseases and normal subjects
    Seung Yeol Park
    Department of Biological Sciences, Korea Advanced Institute of Science and Technology, Daejeon, Republic of Korea
    Int J Cancer 126:142-55. 2010
  3. ncbi request reprint Statistical medium formulation and process modeling by mixture design of experiment for peptide overexpression in recombinant Escherichia coli
    Kwang Min Lee
    Cellular Metabolic Engineering Lab, Korea Advanced Institute of Science and Technology, 373 1 Guseong dong Yuseong gu Daejeon, 305 701, South Korea
    Appl Biochem Biotechnol 135:81-110. 2006
  4. doi request reprint Enhanced sialylation of recombinant erythropoietin in genetically engineered Chinese-hamster ovary cells
    Yeon Tae Jeong
    Department of Biological Sciences, KAIST Korea Advanced Institute of Science and Technology, 335 Gwahangno, Yuseong Gu, Daejeon 305 701, Republic of Korea
    Biotechnol Appl Biochem 52:283-91. 2009
  5. ncbi request reprint Effect of mild-thiol reducing agents and alpha2,3-sialyltransferase expression on secretion and sialylation of recombinant EPO in CHO cells
    Kern Hee Chang
    Department of Biological Sciences, Korea Advanced Institute of Science and Technology, Daejeon 305 701, Korea
    J Microbiol Biotechnol 23:699-706. 2013
  6. doi request reprint Enhancement of xylitol production in Candida tropicalis by co-expression of two genes involved in pentose phosphate pathway
    Irshad Ahmad
    Department of Biological Sciences, Korea Advanced Institute of Science and Technology, 373 1, Guseong Dong, Yuseong Gu, Daejeon, 305 701, Korea
    Bioprocess Biosyst Eng 35:199-204. 2012
  7. doi request reprint Array-based analysis of secreted glycoproteins for rapid selection of a single cell producing a glycoprotein with desired glycosylation
    Sunyoung Park
    Departments of Biological Sciences, Korea Advanced Institute of Science and Technology, 373 1, Guseong Dong, Yuseong Gu, Daejeon 305 701, Korea
    Anal Chem 82:5830-7. 2010
  8. doi request reprint Enhanced sialylation of recombinant human erythropoietin in Chinese hamster ovary cells by combinatorial engineering of selected genes
    Young Dok Son
    Department of Biological Sciences, Korea Advanced Institute of Science and Technology, 335 Gwahangno, Yuseong Gu, Daejeon 305 701, Republic of Korea
    Glycobiology 21:1019-28. 2011
  9. doi request reprint L-arabinose pathway engineering for arabitol-free xylitol production in Candida tropicalis
    Byoung Hoon Yoon
    Department of Biological Sciences, Korea Advanced Institute of Science and Technology, Yuseong Gu, Daejeon, Korea
    Biotechnol Lett 33:747-53. 2011
  10. doi request reprint Effect of heterologous xylose transporter expression in Candida tropicalis on xylitol production rate
    Woo Young Jeon
    Biotechnology Process Engineering Center, Korea Research Institute of Bioscience and Biotechnology KRIBB, 125 Gwahangno, Yuseong Gu, Daejeon, 305 806, Korea
    Bioprocess Biosyst Eng 36:809-17. 2013

Collaborators

Detail Information

Publications19

  1. pmc Xylitol production is increased by expression of codon-optimized Neurospora crassa xylose reductase gene in Candida tropicalis
    Woo Young Jeon
    Department of Biological Sciences, Korea Advanced Institute of Science and Technology, 373 1, Guseong Dong, Yuseong Gu, Daejeon, 305 701, Korea
    Bioprocess Biosyst Eng 35:191-8. 2012
    ..44 g L(-1) h(-1) and xylitol yield of 96% at 44 h, which were 73 and 62%, respectively, higher than corresponding values for BSXDH-3 (rate 0.83 g L(-1) h(-1); yield 59%)...
  2. doi request reprint N-glycosylation status of beta-haptoglobin in sera of patients with colon cancer, chronic inflammatory diseases and normal subjects
    Seung Yeol Park
    Department of Biological Sciences, Korea Advanced Institute of Science and Technology, Daejeon, Republic of Korea
    Int J Cancer 126:142-55. 2010
    ..The identified glycans were sialylated or nonsialylated, bi-antennary or tri-antennary structures, with or without terminal fucosylation...
  3. ncbi request reprint Statistical medium formulation and process modeling by mixture design of experiment for peptide overexpression in recombinant Escherichia coli
    Kwang Min Lee
    Cellular Metabolic Engineering Lab, Korea Advanced Institute of Science and Technology, 373 1 Guseong dong Yuseong gu Daejeon, 305 701, South Korea
    Appl Biochem Biotechnol 135:81-110. 2006
    ..2 mL of NPK sources, 5.6 mL of glucose, and 11.3 mL of MgSO4, and a 3.5-h induction duration time) for T-20 production (13.9%) by applying propagation of error...
  4. doi request reprint Enhanced sialylation of recombinant erythropoietin in genetically engineered Chinese-hamster ovary cells
    Yeon Tae Jeong
    Department of Biological Sciences, KAIST Korea Advanced Institute of Science and Technology, 335 Gwahangno, Yuseong Gu, Daejeon 305 701, Republic of Korea
    Biotechnol Appl Biochem 52:283-91. 2009
    ..The present study provides a useful strategy for enhancing the sialylation of therapeutic glycoproteins produced in CHO cells...
  5. ncbi request reprint Effect of mild-thiol reducing agents and alpha2,3-sialyltransferase expression on secretion and sialylation of recombinant EPO in CHO cells
    Kern Hee Chang
    Department of Biological Sciences, Korea Advanced Institute of Science and Technology, Daejeon 305 701, Korea
    J Microbiol Biotechnol 23:699-706. 2013
    ..Thus, our study is significant in that it offers increased EPO production while still allowing the prevention of decreased sialylation of EPO...
  6. doi request reprint Enhancement of xylitol production in Candida tropicalis by co-expression of two genes involved in pentose phosphate pathway
    Irshad Ahmad
    Department of Biological Sciences, Korea Advanced Institute of Science and Technology, 373 1, Guseong Dong, Yuseong Gu, Daejeon, 305 701, Korea
    Bioprocess Biosyst Eng 35:199-204. 2012
    ..25 g l(-1) h(-1), 21% higher than the rate (1.04 g l(-1) h(-1)) in BSXDH-3. This is the first report of increased metabolic flux toward PPP in C. tropicalis for NADPH regeneration and enhanced xylitol production...
  7. doi request reprint Array-based analysis of secreted glycoproteins for rapid selection of a single cell producing a glycoprotein with desired glycosylation
    Sunyoung Park
    Departments of Biological Sciences, Korea Advanced Institute of Science and Technology, 373 1, Guseong Dong, Yuseong Gu, Daejeon 305 701, Korea
    Anal Chem 82:5830-7. 2010
    ..This method may find widespread use in the clonal selection for the production of other glycoproteins with specific glycosylation as well as analysis of the heterogeneity in cell populations in a high-throughput manner...
  8. doi request reprint Enhanced sialylation of recombinant human erythropoietin in Chinese hamster ovary cells by combinatorial engineering of selected genes
    Young Dok Son
    Department of Biological Sciences, Korea Advanced Institute of Science and Technology, 335 Gwahangno, Yuseong Gu, Daejeon 305 701, Republic of Korea
    Glycobiology 21:1019-28. 2011
    ..The newly constructed host CHO cell lines produced more highly sialylated therapeutic glycoproteins through overexpression of sialuria-mutated GNE/MNK, CMP-SAT and α2,3-ST...
  9. doi request reprint L-arabinose pathway engineering for arabitol-free xylitol production in Candida tropicalis
    Byoung Hoon Yoon
    Department of Biological Sciences, Korea Advanced Institute of Science and Technology, Yuseong Gu, Daejeon, Korea
    Biotechnol Lett 33:747-53. 2011
    ..5 g L-arabinose l(-1) for cell growth without forming arabitol. Moreover, JY produced xylitol with 42 and 16% higher productivity than BSXDH-3 and KNV, respectively...
  10. doi request reprint Effect of heterologous xylose transporter expression in Candida tropicalis on xylitol production rate
    Woo Young Jeon
    Biotechnology Process Engineering Center, Korea Research Institute of Bioscience and Biotechnology KRIBB, 125 Gwahangno, Yuseong Gu, Daejeon, 305 806, Korea
    Bioprocess Biosyst Eng 36:809-17. 2013
    ..Membrane protein extraction and Western blot analysis confirmed the successful heterologous expression and membrane localization of the xylose transporter in C. tropicalis...
  11. ncbi request reprint Sequential and simultaneous statistical optimization by dynamic design of experiment for peptide overexpression in recombinant Escherichia coli
    Kwang Min Lee
    Cellular Metabolic Engineering Lab, Korea Advanced Institute of Science and Technology, 373 1 Guseong dong Yuseong gu Daejeon, 305 701, South Korea
    Appl Biochem Biotechnol 135:59-80. 2006
    ..This statistical optimization allowed the production of T-20 to be increased more than twofold (from 6 to 14%) within a shorter induction duration (from 6 to 4 h) at the shake-flask scale...
  12. ncbi request reprint Enhancement of xylitol productivity and yield using a xylitol dehydrogenase gene-disrupted mutant of Candida tropicalis under fully aerobic conditions
    Byoung Sam Ko
    Department of Biological Sciences, Korea Advanced Institute of Science and Technology, 373 1 Guseong dong, Yuseong Gu, Daejeon, 305 701, Republic of Korea
    Biotechnol Lett 28:1159-62. 2006
    ..Under the optimum conditions, the volumetric productivity and xylitol yield were 3.2 g l(-1) h(-1) and 97% (w/w), respectively...
  13. ncbi request reprint Over-production of beta-carotene from metabolically engineered Escherichia coli
    Sung Woo Kim
    AceBiotech Co Ltd, No 114 Bio Venture Center, Korea Research Institute of Bioscience and Biotechnology KRIBB, Yuseong, Daejeon, Korea
    Biotechnol Lett 28:897-904. 2006
    ..The maximal beta-carotene yields achieved using the 50 l and 300 l fermentor were 390 mg l(-1) and 240 mg l(-1), respectively, with overall productivities of 7.8 mg l(-1) h(-1) and 4.8 mg l(-1) h(-1)...
  14. pmc Globoside promotes activation of ERK by interaction with the epidermal growth factor receptor
    Seung Yeol Park
    Department of Biological Sciences, Korea Advanced Institute of Science and Technology, Daejeon, 305 701, Republic of Korea
    Biochim Biophys Acta 1820:1141-8. 2012
    ..However, the functional role and molecular mechanism of Gb4 are so far unknown...
  15. pmc Production of xylitol from D-xylose by a xylitol dehydrogenase gene-disrupted mutant of Candida tropicalis
    Byoung Sam Ko
    Department of Biological Sciences, Korea Advanced Institute of Science and Technology, 373 1 Guseong dong, Yuseong Gu, Daejeon 305 701, Republic of Korea
    Appl Environ Microbiol 72:4207-13. 2006
    ..23 g liter(-1) h(-1), a specific productivity of 0.76 g g(-1) h(-1), and a xylitol yield of 98%. This is the first report of gene disruption of C. tropicalis for enhancing the efficiency of xylitol production...
  16. ncbi request reprint Enhanced sialylation of recombinant erythropoietin in CHO cells by human glycosyltransferase expression
    Yeon Tae Jeong
    Department of Biological Sciences, KAIST, Daejeon 305 701, Korea
    J Microbiol Biotechnol 18:1945-52. 2008
    ..Thus, coexpression of alpha2,3-ST and beta1,4-GT may be beneficial for producing therapeutic glycoproteins with enhanced sialylation in CHO cells...
  17. ncbi request reprint Molecular cloning and characterization of NAD(+)-dependent xylitol dehydrogenase from Candida tropicalis ATCC 20913
    Byoung Sam Ko
    Department of Biological Sciences, Korea Advanced Institute of Science and Technology, 373 1 Guseong dong, Yuseong Gu, Daejeon 305 701, Republic of Korea
    Biotechnol Prog 22:1708-14. 2006
    ..The recombinant xylitol dehydrogenase expressed in Escherichia coli oxidized polyols such as xylitol and d-sorbitol and reduced ketoses such as d-xylulose and d-fructose. It required exclusively NAD or NADH as a cofactor...
  18. ncbi request reprint Dimeric Le(a) (Le(a)-on-Le(a)) status of beta-haptoglobin in sera of colon cancer, chronic inflammatory disease and normal subjects
    Seung Yeol Park
    Department of Biological Sciences, Korea Advanced Institute of Science and Technology, Daejeon 305 701, Republic of Korea
    Int J Oncol 36:1291-7. 2010
    ..ii) Strong reactivity of Colo205 supernatant with ST421 was reduced clearly by pre-incubation of cells with benzyl-alpha-GalNAc...
  19. pmc Metabolic engineering of a reduced-genome strain of Escherichia coli for L-threonine production
    Jun Hyoung Lee
    Department of Biological Sciences, Korea Advanced Institute of Science and Technology, Daejeon 305 701, Korea
    Microb Cell Fact 8:2. 2009
    ..abstract:..