Affiliation: Korea Advanced Institute of Science and Technology
Kim M, Kim C, Kim S, Shin S, Choe E, Park S, et al
. YAP-Induced PD-L1 Expression Drives Immune Evasion in BRAFi-Resistant Melanoma. Cancer Immunol Res. 2018;: pubmed publisher
..i>Cancer Immunol Res; 6(3); 1-12. Â©2018 AACR. ..
Ji Y, Chae S, Lee H, Park I, Kim C, Ismail T, et al
. Peroxiredoxin5 controls vertebrate ciliogenesis by modulating mitochondrial ROS. Antioxid Redox Signal. 2018;: pubmed publisher
..The loss of Prdx5 is associated with excessive production of ROS resulting in mitochondrial dysfunction and aberrant ciliogenesis. ..
Kim M, Kim J, Hong H, Lee S, Lee J, Jung E, et al
. Actin remodeling confers BRAF inhibitor resistance to melanoma cells through YAP/TAZ activation. EMBO J. 2016;35:462-78 pubmed publisher
..These results suggest that inhibition of actin remodeling is a potential strategy to suppress resistance in BRAF inhibitor therapies. ..
Hong H, Kim J, Kim J. Myosin heavy chain 10 (MYH10) is required for centriole migration during the biogenesis of primary cilia. Biochem Biophys Res Commun. 2015;461:180-5 pubmed publisher
..Our results indicate that MYH10 contributes to ciliogenesis in RPE1 cells by promoting cortical actin-dependent centriole migration. ..
Kim M, Kim J. Role of YAP/TAZ transcriptional regulators in resistance to anti-cancer therapies. Cell Mol Life Sci. 2017;74:1457-1474 pubmed publisher
..The widespread involvement of YAP and TAZ in resistance mechanisms suggests that therapeutic targeting of YAP and TAZ may expedite the development of effective anti-resistance therapies. ..
Lee S, Joo K, Jung E, Hong H, Seo J, Kim J. Export of membrane proteins from the Golgi complex to the primary cilium requires the kinesin motor, KIFC1. FASEB J. 2018;32:957-968 pubmed publisher
..Lee, S.-H., Joo, K., Jung, E. J., Hong, H., Seo, J., Kim, J. Export of membrane proteins from the Golgi complex to the primary cilium requires the kinesin motor, KIFC1. ..