Affiliation: Korea Institute of Science and Technology
- An intramolecular spin of the LDL receptor beta propellerHyesung Jeon
Department of Pathology, Brigham and Women s Hospital and Harvard Medical School, 75 Francis Street, Boston, MA 02115, USA
Structure 11:133-6. 2003..3, now suggests an elegant model to explain how lipoprotein ligands are released from the receptor by exposure to the low-pH environment of the endosome...
- Global defects in the expression and function of the low density lipoprotein receptor (LDLR) associated with two familial hypercholesterolemia mutations resulting in misfolding of the LDLR epidermal growth factor-AB pairEmma J Boswell
Department of Biochemistry, Division of Structural Biology, University of Oxford, South Parks Road, Oxford OX1 3QU, United Kingdom
J Biol Chem 279:30611-21. 2004..The results also highlight a range of misfolding defects that may be associated with familial hypercholesterolemia and may enable the prediction of the consequences of homologous disease-causing mutations to other proteins...
- Structure and physiologic function of the low-density lipoprotein receptorHyesung Jeon
Life Sciences Division, Korea Institute of Science and Technology, Seoul 136 791, Korea
Annu Rev Biochem 74:535-62. 2005....
- Cellular uptake mechanism and intracellular fate of hydrophobically modified glycol chitosan nanoparticlesHae Yun Nam
Biomedical Research Center, Korea Institute of Science and Technology, 39 1 Hawolgok Dong, Seongbuk gu, Seoul 136 791, South South Korea
J Control Release 135:259-67. 2009....
- Cooperation between fixed and low pH-inducible interfaces controls lipoprotein release by the LDL receptorNatalia Beglova
Department of Pathology, Brigham and Women s Hospital and Harvard Medical School, 77 Avenue Louis Pasteur, Boston, MA 02115, USA
Mol Cell 16:281-92. 2004..This finely tuned balance between interdomain rigidity and flexibility is likely to represent a shared structural feature in proteins of the LDL receptor family...