S Cho

Summary

Affiliation: Korea Research Institute of Bioscience and Biotechnology
Country: Korea

Publications

  1. ncbi request reprint Binding and regulation of HIF-1alpha by a subunit of the proteasome complex, PSMA7
    S Cho
    Center for Cellular Switch Protein Structure, Korea Research Institute of Bioscience and Biotechnology, Yusong, Taejon, South Korea
    FEBS Lett 498:62-6. 2001
  2. ncbi request reprint Structural basis of the redox switch in the OxyR transcription factor
    H Choi
    Center for Cellular Switch Protein Structure, Korea Research Institute of Bioscience and, Biotechnology, P O Box 115, Yusong, 305 600, Taejon, South Korea
    Cell 105:103-13. 2001
  3. pmc Sex-specific and non-sex-specific oligomerization domains in both of the doublesex transcription factors from Drosophila melanogaster
    W An
    Department of Biochemistry, Brandeis University, Waltham, Massachusetts 02254 9110, USA
    Mol Cell Biol 16:3106-11. 1996
  4. pmc Purification and physical properties of the male and female double sex proteins of Drosophila
    S Cho
    Department of Biochemistry and The Rosenstiel Center, Brandeis University, Waltham, MA 02254 9110, USA
    Proc Natl Acad Sci U S A 93:2043-7. 1996
  5. ncbi request reprint Binding of p300/CBP co-activators by polyoma large T antigen
    S Cho
    Department of Pathology, Harvard Medical School, Boston, Massachusetts 02115, USA
    J Biol Chem 276:33533-9. 2001
  6. ncbi request reprint Linkage between oligomerization and DNA binding in Drosophila doublesex proteins
    S Cho
    The Rosenstiel Center, The Graduate Department of Biochemistry, Brandeis University, Waltham, Massachusetts 02254 9110, USA
    Biochemistry 37:11301-8. 1998
  7. pmc Specification of germ cell fates by FOG-3 has been conserved during nematode evolution
    P J Chen
    Department of Biology, University of Michigan, Ann Arbor, Michigan 48109, USA
    Genetics 158:1513-25. 2001
  8. ncbi request reprint 9-cis-Retinoic acid represses transcription of the gonadotropin-releasing hormone (GnRH) gene via proximal promoter region that is distinct from all-trans-retinoic acid response element
    S Cho
    School of Biological Sciences and Research Center for Cell Differentiation, Seoul National University, Seoul, 151-742, South Korea
    Brain Res Mol Brain Res 87:214-22. 2001
  9. ncbi request reprint A functional retinoic acid response element (RARE) is present within the distal promoter of the rat gonadotropin-releasing hormone (GnRH) gene
    S Cho
    School of Biological Sciences and Research Center for Cell Differentiation, Seoul National University, Seoul, 151-742, South Korea
    Brain Res Mol Brain Res 87:204-13. 2001
  10. ncbi request reprint Evidence for direct involvement of beta-catenin in phorbol ester-induced neurite outgrowth in GT1-1 hypothalamic neurones
    W Sun
    School of Biological Sciences, College of Natural Sciences, Seoul National University, Seoul 151-742, Korea
    J Neuroendocrinol 13:249-60. 2001

Collaborators

  • G Storz
  • Hidemi Ishii
  • Jiali Han
  • S Kim
  • W Sun
  • H Choi
  • P J Chen
  • K M Chung
  • T J McDonnell
  • J H Lim
  • W An
  • P Mukhopadhyay
  • S W Jin
  • D H Kim
  • K Kim
  • R E Ellis
  • J Woo
  • H Lee
  • Y Choe
  • S E Ryu
  • O K Song
  • J Lee
  • B Hahm
  • J E Kim
  • J Lim
  • M Seedorf
  • S K Jang
  • L L Amelse
  • G Lozano
  • A Chavez-Reyes
  • R Montes de Oca Luna
  • B Y Ahn
  • Y G Yu
  • Y Cho
  • Y S Han
  • P C Wensink

Detail Information

Publications17

  1. ncbi request reprint Binding and regulation of HIF-1alpha by a subunit of the proteasome complex, PSMA7
    S Cho
    Center for Cellular Switch Protein Structure, Korea Research Institute of Bioscience and Biotechnology, Yusong, Taejon, South Korea
    FEBS Lett 498:62-6. 2001
    ..PSMA7 inhibited the transactivation function of HIF-1alpha under both normoxic and hypoxia-mimicking conditions. In addition, we show that the PSMA7-mediated regulation of HIF-1alpha activity is associated with the proteasome pathway...
  2. ncbi request reprint Structural basis of the redox switch in the OxyR transcription factor
    H Choi
    Center for Cellular Switch Protein Structure, Korea Research Institute of Bioscience and, Biotechnology, P O Box 115, Yusong, 305 600, Taejon, South Korea
    Cell 105:103-13. 2001
    ....
  3. pmc Sex-specific and non-sex-specific oligomerization domains in both of the doublesex transcription factors from Drosophila melanogaster
    W An
    Department of Biochemistry, Brandeis University, Waltham, Massachusetts 02254 9110, USA
    Mol Cell Biol 16:3106-11. 1996
    ..We speculate that the common function of OD1 and OD2 is to oligomerize the full-length proteins, whereas their specialized functions are to form a dimeric DNA binding unit and a sex-specific transcriptional activation or repression unit...
  4. pmc Purification and physical properties of the male and female double sex proteins of Drosophila
    S Cho
    Department of Biochemistry and The Rosenstiel Center, Brandeis University, Waltham, MA 02254 9110, USA
    Proc Natl Acad Sci U S A 93:2043-7. 1996
    ..These oligomerization and DNA binding properties are indistinguishable between the male and female proteins...
  5. ncbi request reprint Binding of p300/CBP co-activators by polyoma large T antigen
    S Cho
    Department of Pathology, Harvard Medical School, Boston, Massachusetts 02115, USA
    J Biol Chem 276:33533-9. 2001
    ....
  6. ncbi request reprint Linkage between oligomerization and DNA binding in Drosophila doublesex proteins
    S Cho
    The Rosenstiel Center, The Graduate Department of Biochemistry, Brandeis University, Waltham, Massachusetts 02254 9110, USA
    Biochemistry 37:11301-8. 1998
    ..6; DSXM, k12 = 5.4). This suggests that the sex-specific domains may have a second effect on DNA binding, namely, an effect on binding cooperativity that depends on the number and arrangement of DNA sites...
  7. pmc Specification of germ cell fates by FOG-3 has been conserved during nematode evolution
    P J Chen
    Department of Biology, University of Michigan, Ann Arbor, Michigan 48109, USA
    Genetics 158:1513-25. 2001
    ..elegans hermaphrodites, we propose that alterations in the upstream sex-determination pathway, perhaps acting through TRA-1A, allow spermatogenesis in C. elegans and C. briggsae XX larvae but not in C. remanei...
  8. ncbi request reprint 9-cis-Retinoic acid represses transcription of the gonadotropin-releasing hormone (GnRH) gene via proximal promoter region that is distinct from all-trans-retinoic acid response element
    S Cho
    School of Biological Sciences and Research Center for Cell Differentiation, Seoul National University, Seoul, 151-742, South Korea
    Brain Res Mol Brain Res 87:214-22. 2001
    ..In conclusion, the present study clearly demonstrates that 9-cis-RA is a negative regulator of GnRH gene expression in immortalized GnRH neurons...
  9. ncbi request reprint A functional retinoic acid response element (RARE) is present within the distal promoter of the rat gonadotropin-releasing hormone (GnRH) gene
    S Cho
    School of Biological Sciences and Research Center for Cell Differentiation, Seoul National University, Seoul, 151-742, South Korea
    Brain Res Mol Brain Res 87:204-13. 2001
    ..Taken together, these data indicate that all-trans-RA enhances GnRH transcription via functional RARE present in the distal region of the GnRH promoter...
  10. ncbi request reprint Evidence for direct involvement of beta-catenin in phorbol ester-induced neurite outgrowth in GT1-1 hypothalamic neurones
    W Sun
    School of Biological Sciences, College of Natural Sciences, Seoul National University, Seoul 151-742, Korea
    J Neuroendocrinol 13:249-60. 2001
    ..Moreover, TPA was found to increase the transcription-activational roles of beta-catenin. Together, these data provide evidence that beta-catenin is involved in the TPA-induced functional differentiation of immortalized GnRH neurones...
  11. ncbi request reprint Antisense palmitoyl protein thioesterase 1 (PPT1) treatment inhibits PPT1 activity and increases cell death in LA-N-5 neuroblastoma cells
    S Cho
    Departments of Pediatrics, Biochemistry and Molecular Biology, University of Chicago, Chicago, Illinois, USA
    J Neurosci Res 62:234-40. 2000
    ..Drugs that raise the level of protein palmitoylation are pro-apoptotic and PPT1 inhibition may enhance the killing efficacy of chemotherapeutic agents used to kill neuroblastoma-derived cells...
  12. pmc Nonstructural protein 5A of hepatitis C virus inhibits the function of karyopherin beta3
    K M Chung
    Department of Life Science, Pohang University of Science and Technology, Pohang, Kyungbuk 790 784, Korea
    J Virol 74:5233-41. 2000
    ..This indicates that NS5A may inhibit karyopherin beta3 function via protein-protein interaction. The role of NS5A in HCV replication is discussed...
  13. ncbi request reprint Palmitoyl protein thioesterase 1 protects against apoptosis mediated by Ras-Akt-caspase pathway in neuroblastoma cells
    S Cho
    Department of Pediatrics, University of Chicago, Illinois, USA
    J Neurochem 74:1478-88. 2000
    ..PPT overexpression also led to reduced membrane association of another palmitoylated protein, GAP-43, a neuron-specific protein. Our studies suggest that protein palmitoylation could be a physiological regulator of apoptosis...
  14. ncbi request reprint Loss of one but not two mdm2 null alleles alters the tumour spectrum in p53 null mice
    T J McDonnell
    Department of Molecular Pathology, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    J Pathol 188:322-8. 1999
    ..These data raise the possibility that heterozygosity at the mdm2 locus in the absence of p53 affects the development of tumours of mesenchymal origin...
  15. ncbi request reprint The crystal structure of an Fe-superoxide dismutase from the hyperthermophile Aquifex pyrophilus at 1.9 A resolution: structural basis for thermostability
    J H Lim
    Structural Biology Center, Korea Institute of Science and Technology, Seoul, South Korea
    J Mol Biol 270:259-74. 1997
    ..Comparisons of the Ap SOD structure with that of other known enzymes from hyperthermophiles reveal that the increased number of intrasubunit ion-pairs is a common feature...
  16. ncbi request reprint DNA binding by the male and female doublesex proteins of Drosophila melanogaster
    S Cho
    Rosenstiel Center and the Graduate Department of Biochemistry, Brandeis University, Waltham, Massachusetts 02254 9110, USA
    J Biol Chem 272:3185-9. 1997
    ..We infer that the sex-specific oligomerization domains play roles in binding cooperativity to multiple DNA sites or in other protein:protein interactions...
  17. ncbi request reprint Role of palmitoyl-protein thioesterase in cell death: implications for infantile neuronal ceroid lipofuscinosis
    S Cho
    Departments of Pediatrics, Biochemistry and Molecular Biology, University of Chicago, Chicago, IL 60637, USA
    Eur J Paediatr Neurol 5:53-5. 2001
    ..In contrast, overexpression of PPT1 led to increased resistance to cell death induced by these drugs...