Lee B, Kim J, Choi E, Cho J, Kim E. Effect of young exosomes injected in aged mice. Int J Nanomedicine. 2018;13:5335-5345 pubmed publisher
..These results indicate that exosomes from young mice could reverse the expression pattern of aging-associated molecules in aged mice. Eventually, exosomes may be used as a novel approach for the treatment and diagnosis of aging animals. ..
Kim H, Kim E, Ha T, Jeong S, Lee S, Lee S, et al
. Thiol-responsive gemini poly(ethylene glycol)-poly(lactide) with a cystine disulfide spacer as an intracellular drug delivery nanocarrier. Colloids Surf B Biointerfaces. 2015;127:206-12 pubmed publisher
Kim S, Choi E, Lee H, Moon C, Kim E. Transthyretin as a new transporter of nanoparticles for receptor-mediated transcytosis in rat brain microvessels. Colloids Surf B Biointerfaces. 2015;136:989-96 pubmed publisher
..Taken together, these results indicate that Ttr is a new putative transporter for nanomedicines across the BBB. ..
Jang W, Lee B, Jeong J, Sung Y, Choi M, Song P, et al
. Overexpression of serum amyloid a 1 induces depressive-like behavior in mice. Brain Res. 2017;1654:55-65 pubmed publisher
..The results showed that TG mice have a tendency to avoid stranger mice and an impaired social recognition. In conclusion, the SAA1 TG mouse model is a valuable model to study depression. ..
Kim J, Lee B, Choi E, Lee K, Choi S, Cho J, et al
. Reverse Expression of Aging-Associated Molecules through Transfection of miRNAs to Aged Mice. Mol Ther Nucleic Acids. 2017;6:106-115 pubmed publisher
..This study provides preliminary data on reverse aging, which could be applied further for treatments of adult diseases. ..
Lee B, Kim H, Choi E, Cho J, Kim N, Kim J, et al
. Enhanced Therapeutic Treatment of Colorectal Cancer Using Surface-Modified Nanoporous Acupuncture Needles. Sci Rep. 2017;7:12900 pubmed publisher
..Surface modification of acupuncture needles further enhances the therapeutic effects of acupuncture treatment in CRC rats. ..
Kim J, Seo A, Kim J, Choi S, Yoon H, Kim E, et al
. A Multimodal Biomicroscopic System based on High-frequency Acoustic Radiation Force Impulse and Multispectral Imaging Techniques for Tumor Characterization Ex vivo. Sci Rep. 2017;7:17518 pubmed publisher
..These results therefore suggest that the multimodal biomicroscopic system has the potential to undertake qualitative characterizations of excised tumors ex vivo. ..