Su Hyun Jo
Affiliation: Kangwon National University
- Kim S, Lee E, Lee K, Jo S, Seo S. PKA regulates calcineurin function through the phosphorylation of RCAN1: identification of a novel phosphorylation site. Biochem Biophys Res Commun. 2015;459:604-9 pubmed publisher..Our results suggest the presence of a novel phosphorylation site in RCAN1 and that its phosphorylation influences calcineurin-dependent inflammatory target gene expression. ..
- Jo S, Hong H, Chong S, Choe H. Protriptyline block of the human ether-à-go-go-related gene (HERG) K+ channel. Life Sci. 2008;82:331-40 pubmed publisher..Our findings suggest that inhibition of HERG currents may contribute to the arrhythmogenic side effects of protriptyline. ..
- Jo S, Hong H, Chong S, Lee H, Choe H. H(1) antihistamine drug promethazine directly blocks hERG K(+) channel. Pharmacol Res. 2009;60:429-37 pubmed publisher..These results suggest that promethazine is a blocker of the hERG channels, providing a molecular mechanism for the arrhythmogenic side effects during the clinical administration of promethazine...
- Lee K, Kim Y, Cho Y, Chung S, Jo S, Choi S. Polychlorinated biphenyl 19 blocks the most common form of store-operated Ca2+ entry through Orai. Naunyn Schmiedebergs Arch Pharmacol. 2017;390:1221-1228 pubmed publisher..These results imply that PCB19 inhibits not only TRPC-mediated SOCE as in PC12 cells but also Orai-mediated SOCE as in many other cells including HEK293, Jurkat T and HL-60 cells. ..