Byung Soo Kim

Summary

Affiliation: Hanyang University
Country: Korea

Publications

  1. ncbi request reprint Tissue engineering of cartilage with chondrocytes cultured in a chemically-defined, serum-free medium
    Byung Soo Kim
    Department of Chemical Engineering, Hanyang University, Seoul 133 791, Korea
    Biotechnol Lett 26:709-12. 2004
  2. doi request reprint Orthotopic bone formation by implantation of apatite-coated poly(lactide-co-glycolide)/hydroxyapatite composite particulates and bone morphogenetic protein-2
    Sang Soo Kim
    Department of Bioengineering, Hanyang University, Seoul 133 791, Korea
    J Biomed Mater Res A 87:245-53. 2008
  3. doi request reprint Locally delivered growth factor enhances the angiogenic efficacy of adipose-derived stromal cells transplanted to ischemic limbs
    Suk Ho Bhang
    Department of Bioengineering, College of Medicine, Hanyang University, Seoul, Korea
    Stem Cells 27:1976-86. 2009
  4. ncbi request reprint Preliminary experience with tissue engineering of a venous vascular patch by using bone marrow-derived cells and a hybrid biodegradable polymer scaffold
    Seung Woo Cho
    Department of Bioengineering, Hanyang University, Seoul, Korea School of Chemical and Biological Engineering, Seoul, Korea
    J Vasc Surg 44:1329-40. 2006
  5. ncbi request reprint Pretreatment serum level of 15-kDa granulysin might have a prognostic value in patients with diffuse large B cell lymphoma
    Yong Park
    Division of Hematology Oncology, Department of Internal Medicine, Korea University College of Medicine, Seoul, Korea
    Acta Haematol 126:79-86. 2011
  6. ncbi request reprint Implantation of bone marrow mononuclear cells using injectable fibrin matrix enhances neovascularization in infarcted myocardium
    Ju Hee Ryu
    Department of Chemical Engineering, Hanyang University, 17 Haengdang dong, Seongdong Gu, Seoul 133 791, South Korea
    Biomaterials 26:319-26. 2005
  7. ncbi request reprint Smooth muscle-like tissues engineered with bone marrow stromal cells
    Seung Woo Cho
    Department of Chemical Engineering, Hanyang University, 17 Haengdang dong, Seongdong Gu, Seoul 133 791, South Korea
    Biomaterials 25:2979-86. 2004
  8. ncbi request reprint The enhancement of recombinant protein production by polymer nanospheres in cell suspension culture
    Ju Hee Ryu
    Department of Chemical Engineering, Hanyang University, 17 Haengdang dong, Seongdong Gu, Seoul 133 791, South Korea
    Biomaterials 26:2173-81. 2005
  9. ncbi request reprint The use of poly(lactic-co-glycolic acid) microspheres as injectable cell carriers for cartilage regeneration in rabbit knees
    Sun Woong Kang
    Department of Chemical Engineering, Hanyang University, Seoul 133 791, South Korea
    J Biomater Sci Polym Ed 17:925-39. 2006
  10. ncbi request reprint Vascular patches tissue-engineered with autologous bone marrow-derived cells and decellularized tissue matrices
    Seung Woo Cho
    Department of Chemical Engineering, Hanyang University, 17 Haengdang dong, Seongdong Gu, Seoul 133 791, Republic of Korea
    Biomaterials 26:1915-24. 2005

Detail Information

Publications121 found, 100 shown here

  1. ncbi request reprint Tissue engineering of cartilage with chondrocytes cultured in a chemically-defined, serum-free medium
    Byung Soo Kim
    Department of Chemical Engineering, Hanyang University, Seoul 133 791, Korea
    Biotechnol Lett 26:709-12. 2004
    ....
  2. doi request reprint Orthotopic bone formation by implantation of apatite-coated poly(lactide-co-glycolide)/hydroxyapatite composite particulates and bone morphogenetic protein-2
    Sang Soo Kim
    Department of Bioengineering, Hanyang University, Seoul 133 791, Korea
    J Biomed Mater Res A 87:245-53. 2008
    ..The local and sustained delivery system for BMP-2 developed in this study may be useful as a carrier for BMP-2 and would enhance bone regeneration efficacy for the treatment of large bone defects...
  3. doi request reprint Locally delivered growth factor enhances the angiogenic efficacy of adipose-derived stromal cells transplanted to ischemic limbs
    Suk Ho Bhang
    Department of Bioengineering, College of Medicine, Hanyang University, Seoul, Korea
    Stem Cells 27:1976-86. 2009
    ..This study demonstrates the potential of hADSCs in combination with growth factors for use in the treatment of ischemia...
  4. ncbi request reprint Preliminary experience with tissue engineering of a venous vascular patch by using bone marrow-derived cells and a hybrid biodegradable polymer scaffold
    Seung Woo Cho
    Department of Bioengineering, Hanyang University, Seoul, Korea School of Chemical and Biological Engineering, Seoul, Korea
    J Vasc Surg 44:1329-40. 2006
    ..The objective of this study was to develop a tissue-engineered vascular patch by using autologous bone marrow-derived cells (BMCs) and a hybrid biodegradable polymer scaffold...
  5. ncbi request reprint Pretreatment serum level of 15-kDa granulysin might have a prognostic value in patients with diffuse large B cell lymphoma
    Yong Park
    Division of Hematology Oncology, Department of Internal Medicine, Korea University College of Medicine, Seoul, Korea
    Acta Haematol 126:79-86. 2011
    ..We evaluated the prognostic significance of the pretreatment serum level of 15-kDa granulysin in patients with diffuse large B cell lymphoma (DLBCL)...
  6. ncbi request reprint Implantation of bone marrow mononuclear cells using injectable fibrin matrix enhances neovascularization in infarcted myocardium
    Ju Hee Ryu
    Department of Chemical Engineering, Hanyang University, 17 Haengdang dong, Seongdong Gu, Seoul 133 791, South Korea
    Biomaterials 26:319-26. 2005
    ..2 +/- 0.7 microm) and medium injection group (7.3 +/- 0.5 microm). These results suggest that fibrin matrix could serve as a cell implantation matrix that enhances neovascularization efficacy for myocardial infarction treatment...
  7. ncbi request reprint Smooth muscle-like tissues engineered with bone marrow stromal cells
    Seung Woo Cho
    Department of Chemical Engineering, Hanyang University, 17 Haengdang dong, Seongdong Gu, Seoul 133 791, South Korea
    Biomaterials 25:2979-86. 2004
    ..Non-seeded scaffolds (control groups) retrieved 4 weeks after implantation did not exhibit extensive tissue formation. This study demonstrates the potential of BMSCs as an alternative cell source for tissue engineering of SM...
  8. ncbi request reprint The enhancement of recombinant protein production by polymer nanospheres in cell suspension culture
    Ju Hee Ryu
    Department of Chemical Engineering, Hanyang University, 17 Haengdang dong, Seongdong Gu, Seoul 133 791, South Korea
    Biomaterials 26:2173-81. 2005
    ..The nanosphere suspension culture method developed in this study may be useful for the mass production of recombinant proteins through large-scale suspension culture of anchorage-dependent animal cells...
  9. ncbi request reprint The use of poly(lactic-co-glycolic acid) microspheres as injectable cell carriers for cartilage regeneration in rabbit knees
    Sun Woong Kang
    Department of Chemical Engineering, Hanyang University, Seoul 133 791, South Korea
    J Biomater Sci Polym Ed 17:925-39. 2006
    ..This study demonstrates the feasibility of using PLGA microspheres as an injectable scaffold for cartilage regeneration in a rabbit model of osteochondral wound repair...
  10. ncbi request reprint Vascular patches tissue-engineered with autologous bone marrow-derived cells and decellularized tissue matrices
    Seung Woo Cho
    Department of Chemical Engineering, Hanyang University, 17 Haengdang dong, Seongdong Gu, Seoul 133 791, Republic of Korea
    Biomaterials 26:1915-24. 2005
    ..This study demonstrates that vascular patches can be tissue-engineered with autologous BMCs and decellularized tissue matrices...
  11. ncbi request reprint Enhancement of ectopic bone formation by bone morphogenetic protein-2 released from a heparin-conjugated poly(L-lactic-co-glycolic acid) scaffold
    Oju Jeon
    Department of Chemical Engineering, Hanyang University, Sungdong gu, Seoul, Korea
    Biomaterials 28:2763-71. 2007
    ..Collectively, these results demonstrate that the HP-PLGA delivery system is capable of potentiating the osteogenic efficacy of BMP-2, and underscore its importance as a possible bone regeneration strategy...
  12. doi request reprint Enhancement of in vivo bone regeneration efficacy of osteogenically undifferentiated human cord blood mesenchymal stem cells
    Jin Muk Kang
    Department of Bioengineering, Hanyang University, Seoul 133 791, Korea
    J Biomed Mater Res A 93:666-72. 2010
    ....
  13. ncbi request reprint Mechano-active tissue engineering of vascular smooth muscle using pulsatile perfusion bioreactors and elastic PLCL scaffolds
    Sung In Jeong
    School of Chemical Engineering, Hanyang University, Seoul 133 791, Republic of Korea
    Biomaterials 26:1405-11. 2005
    ....
  14. ncbi request reprint Nanosphere-mediated delivery of vascular endothelial growth factor gene for therapeutic angiogenesis in mouse ischemic limbs
    Sun Woong Kang
    Department of Chemical Engineering, Hanyang University, Seoul 133 791, Republic of Korea
    Biomaterials 29:1109-17. 2008
    ..These results indicated that PLGA nanosphere might be useful as a potential carrier for skeletal muscle gene delivery applications...
  15. doi request reprint Human feeder cells can support the undifferentiated growth of human and mouse embryonic stem cells using their own basic fibroblast growth factors
    Yong Park
    Institute of Stem Cell Research, Korea University, Seoul, Korea
    Stem Cells Dev 20:1901-10. 2011
    ..Further, a bFGF-dependent pathway might be crucial for maintaining the undifferentiated characteristics of mouse and human ESCs...
  16. doi request reprint The effect of the controlled release of nerve growth factor from collagen gel on the efficiency of neural cell culture
    Suk Ho Bhang
    Department of Bioengineering, Hanyang University, 17 Hangdang Dong, Sungdong gu, Seoul 133 791, Republic of Korea
    Biomaterials 30:126-32. 2009
    ..This method could economize large-scale culture of stem cells by reducing the amount of costly growth factors needed...
  17. ncbi request reprint Enhancement of in vivo endothelialization of tissue-engineered vascular grafts by granulocyte colony-stimulating factor
    Seung Woo Cho
    Department of Bioengineering, Hanyang University, Seoul 133 791, Korea
    J Biomed Mater Res A 76:252-63. 2006
    ..This study suggests that G-CSF administration could be applied to improve patency of small-diameter tissue-engineered vascular grafts...
  18. ncbi request reprint Accelerated bonelike apatite growth on porous polymer/ceramic composite scaffolds in vitro
    Sang Soo Kim
    Department of Bioengineering, Hanyang University, Seoul, Korea
    Tissue Eng 12:2997-3006. 2006
    ..Therefore, the apatite-coated PLGA/HA scaffolds may provide enhanced osteogenic potential when used as scaffold for bone tissue engineering...
  19. ncbi request reprint A method for the effective formation of hepatocyte spheroids using a biodegradable polymer nanosphere
    So Jung Gwak
    Department of Chemical Engineering, College of Engineering, Hanyang University, Seoul, Korea
    J Biomed Mater Res A 78:268-75. 2006
    ..This new culture method improves upon the conventional method of forming hepatocyte spheroids in terms of spheroid formation efficiency, cell viability, and hepatocyte function...
  20. ncbi request reprint The efficacy of epirubicin, cisplatin, uracil/tegafur, and leucovorin in patients with advanced biliary tract carcinoma
    Kyong Hwa Park
    Division of Oncology Hematology, Department of Internal Medicine, College of Medicine, Korea University, Seoul, Korea
    Cancer 103:2338-43. 2005
    ..However, to our knowledge, to date no effective therapeutic modality has been shown to prolong the survival of patients in the inoperable stages of this disease...
  21. ncbi request reprint Long-term and zero-order release of basic fibroblast growth factor from heparin-conjugated poly(L-lactide-co-glycolide) nanospheres and fibrin gel
    Oju Jeon
    Department of Chemical Engineering, Hanyang University, 17 Haengdang dong, Seongdong Gu, Seoul 133 791, Korea
    Biomaterials 27:1598-607. 2006
    ..This study shows that a bFGF delivery system using HCPNs in fibrin gel exhibits controllable, long-term, zero-order release of bFGF and potentiates the angiogenic efficacy of bFGF administration...
  22. doi request reprint Apatite-coated porous poly(lactic-co-glycolic acid) microspheres as an injectable bone substitute
    Tae Jin Lee
    Department of Bioengineering, Hanyang University, 17 Haengdang dong, Seongdong Gu, Seoul 133 791, South Korea
    J Biomater Sci Polym Ed 21:635-45. 2010
    ..9% versus 14.6%, P < 0.001). Fluorochrome-labeling analysis showed that bone regeneration occurred in the pores of implanted APPMs. The results show that APPM may be useful as a bone substitute in orthopedic applications...
  23. doi request reprint Undifferentiated propagation of the human embryonic stem cell lines, H1 and HSF6, on human placenta-derived feeder cells without basic fibroblast growth factor supplementation
    Yong Park
    Institute of Stem Cell Research, Korea University, Seoul, Korea
    Stem Cells Dev 19:1713-22. 2010
    ....
  24. doi request reprint Heparin-conjugated fibrin as an injectable system for sustained delivery of bone morphogenetic protein-2
    Hee Seok Yang
    Department of Bioengineering, Hanyang University, Seoul, Republic of Korea
    Tissue Eng Part A 16:1225-33. 2010
    ..Since HCF can deliver BMP-2 over a long term, is an injectable system, and is made of clinically benign materials, this system would have advantages for clinical applications to regenerate bone...
  25. doi request reprint Bone morphogenetic protein-2 enhances bone regeneration mediated by transplantation of osteogenically undifferentiated bone marrow-derived mesenchymal stem cells
    Sun Woong Kang
    Department of Chemical Engineering, Hanyang University, Seoul, 133 791, Korea
    Biotechnol Lett 30:1163-8. 2008
    ..These BMP-2-loaded HCPLGA scaffolds could prove invaluable for in vivo regeneration of bone from undifferentiated human BMMSCs...
  26. ncbi request reprint Poly(lactic-co-glycolic acid) microspheres as an injectable scaffold for cartilage tissue engineering
    Sun Woong Kang
    Department of Chemical Engineering, Hanyang University, Seoul, South Korea
    Tissue Eng 11:438-47. 2005
    ..This scaffold may be useful to regenerate cartilaginous tissues through minimally invasive surgical procedures in orthopedic, maxillofacial, and urologic applications...
  27. ncbi request reprint Engineering of volume-stable adipose tissues
    Seung Woo Cho
    Department of Chemical Engineering, Hanyang University, 17 Haengdang dong, Seongdong Gu, Seoul 133 791, Republic of Korea
    Biomaterials 26:3577-85. 2005
    ..This study demonstrates that volume-stable adipose tissues can be engineered in vivo using mechanical support structures. This technique offers the potential for augmentation of adipose tissues with volume conservation...
  28. ncbi request reprint Combined sustained delivery of basic fibroblast growth factor and administration of granulocyte colony-stimulating factor: synergistic effect on angiogenesis in mouse ischemic limbs
    Oju Jeon
    Department of Chemical Engineering, Hanyang University, Seoul, Korea
    J Endovasc Ther 13:175-81. 2006
    ....
  29. ncbi request reprint Effects of culture conditions on osteogenic differentiation in human mesenchymal stem cells
    Su Jin Song
    Department of Chemical Engineering, Hanyang University, Seoul 133 791, Korea
    J Microbiol Biotechnol 17:1113-9. 2007
    ..HA had the highest positive effect on OPN expression and calcium deposition. The interaction between AC, betaG, and HA had the second highest positive effect on ALP activity...
  30. doi request reprint Active blood vessel formation in the ischemic hindlimb mouse model using a microsphere/hydrogel combination system
    Jangwook Lee
    Department of Bioengineering, Hanyang University, Seoul, 133 791, Republic of Korea
    Pharm Res 27:767-74. 2010
    ....
  31. ncbi request reprint Submucosal injection of poly(lactic-co-glycolic acid) microspheres in rabbit bladder as a potential treatment for urinary incontinence and vesicoureteral reflux: preliminary results
    Eui Ri Cho
    Department of Chemical Engineering, Hanyang University, Seoul, South Korea
    J Biomater Sci Polym Ed 16:1109-20. 2005
    ....
  32. ncbi request reprint The behavior of neural stem cells on biodegradable synthetic polymers
    Suk Ho Bhang
    Department of Bioengineering, Hanyang University, Seoul 133 791, South Korea
    J Biomater Sci Polym Ed 18:223-39. 2007
    ..PLGA also showed favorable results for neurite out-growth of HiB5 cells. The results of this study demonstrate the promising biocompatibility of PLGA as a scaffold for neural stem cell transplantation for nerve regeneration...
  33. ncbi request reprint Synergistic effect of sustained delivery of basic fibroblast growth factor and bone marrow mononuclear cell transplantation on angiogenesis in mouse ischemic limbs
    Oju Jeon
    Department of Chemical Engineering, Hanyang University, 17 Haengdang dong, Seongdong Gu, Seoul 133 791, Republic of Korea
    Biomaterials 27:1617-25. 2006
    ..In addition, the combined therapy of SD of bFGF and BMMNC transplantation synergistically enhances angiogenesis in mouse ischemic limb, compared to each separate therapy...
  34. doi request reprint In situ cardiomyogenic differentiation of implanted bone marrow mononuclear cells by local delivery of transforming growth factor-β1
    Hee Seok Yang
    Department of Bioengineering, Hanyang University, Seoul, Republic of Korea
    Cell Transplant 21:299-312. 2012
    ..This method can significantly improve the stem cell therapy technology for myocardial regeneration, since it can remove in vitro cell culture step for cardiomyogenic differentiation prior to cell implantation...
  35. ncbi request reprint Poly(L-lactide-co-glycolide) nanospheres conjugated with a nuclear localization signal for delivery of plasmid DNA
    Oju Jeon
    Departments of Chemical Engineering, Hanyang University, Seoul, South Korea
    J Drug Target 15:190-8. 2007
    ..This study showed that the NLS conjugation enhanced the gene transfection efficiency of the PLGA nanosphere gene delivery system in vitro and that the enhanced gene expression was sustained for at least 13 days...
  36. doi request reprint Enhancement of long-term angiogenic efficacy of adipose stem cells by delivery of FGF2
    Tae Jin Lee
    Department of Bioengineering, Hanyang University, 17 Haengdang dong, Seongdong Gu, Seoul, 133 791, Republic of Korea
    Microvasc Res 84:1-8. 2012
    ..This suggests that FGF2 delivery to hADSC transplantation sites enhances long-term angiogenic efficacy of hADSCs transplanted into ischemic tissues...
  37. doi request reprint Hyaline cartilage regeneration by combined therapy of microfracture and long-term bone morphogenetic protein-2 delivery
    Hee Seok Yang
    Department of Bioengineering, Hanyang University, Seoul, Republic of Korea
    Tissue Eng Part A 17:1809-18. 2011
    ..Therefore, this method could be more convenient for hyaline cartilage regeneration than autologous chondrocyte implantation due to its less invasive nature and lack of cell implantation...
  38. ncbi request reprint Control of basic fibroblast growth factor release from fibrin gel with heparin and concentrations of fibrinogen and thrombin
    Oju Jeon
    Department of Chemical Engineering, Hanyang University, Seoul, Republic of Korea
    J Control Release 105:249-59. 2005
    ..This study showed that the rate of bFGF release from fibrin gels can be controlled and that the bFGF delivery system has therapeutic potentials for angiogenesis...
  39. doi request reprint In vivo bone formation following transplantation of human adipose-derived stromal cells that are not differentiated osteogenically
    Oju Jeon
    Graduate School of Life Science and Biotechnology, Pochon CHA University and CHA Stem Cell Institute, Gangnam Gu, Seoul, Korea
    Tissue Eng Part A 14:1285-94. 2008
    ....
  40. ncbi request reprint Engineered adipose tissue formation enhanced by basic fibroblast growth factor and a mechanically stable environment
    Seung Woo Cho
    Department of Bioengineering, Hanyang University, Seoul 133 791, Korea
    Cell Transplant 16:421-34. 2007
    ..The method described in this study could be useful to augment adipose tissue used in plastic and reconstructive surgery...
  41. ncbi request reprint A poly(lactide-co-glycolide)/hydroxyapatite composite scaffold with enhanced osteoconductivity
    Sang Soo Kim
    Department of Bioengineering, Hanyang University, Seoul 133 791, Korea
    J Biomed Mater Res A 80:206-15. 2007
    ..These results show that the biodegradable polymer/ceramic composite scaffolds fabricated with the novel GF/PL method can enhance bone regeneration compared with those fabricated with the conventional SC/PL method...
  42. ncbi request reprint Regeneration of whole meniscus using meniscal cells and polymer scaffolds in a rabbit total meniscectomy model
    Sun Woong Kang
    Department of Chemical Engineering, Hanyang University, Seoul 133 791, Korea
    J Biomed Mater Res A 77:659-71. 2006
    ..This study demonstrates, for the first time, the feasibility of regenerating whole meniscal cartilage in a rabbit total meniscectomy model using the tissue engineering method...
  43. ncbi request reprint Enhancement of angiogenic efficacy of human cord blood cell transplantation
    Seung Woo Cho
    Department of Bioengineering, Hanyang University, Seoul, Korea
    Tissue Eng 12:1651-61. 2006
    ..Combined therapy of sustained release of angiogenic protein and angiogenic cell transplantation synergistically enhances angiogenesis in ischemic limbs compared to each therapy separately...
  44. ncbi request reprint Skin regeneration using keratinocytes and dermal fibroblasts cultured on biodegradable microspherical polymer scaffolds
    Sang Soo Kim
    Department of Chemical Engineering, Hanyang University, 17 Haengdang dong, Seongdong Gu, Seoul 133 791, Korea
    J Biomed Mater Res B Appl Biomater 75:369-77. 2005
    ..These results suggest that transplantation of keratinocytes and dermal fibroblasts cultured on PLGA microspheres could be potentially useful as an alternative to bioartificial skin grafts for the treatment of skin wounds...
  45. ncbi request reprint Tissue engineering of heart valves in vivo using bone marrow-derived cells
    Sang Soo Kim
    Interdisciplinary Program for Biochemical Engineering and Biotechnology, Seoul National University, Seoul, Korea
    Artif Organs 30:554-7. 2006
    ..This study reports, for the first time, on tissue engineering of heart valve in vivo using BMCs...
  46. ncbi request reprint Granulocyte colony-stimulating factor treatment enhances the efficacy of cellular cardiomyoplasty with transplantation of embryonic stem cell-derived cardiomyocytes in infarcted myocardium
    Seung Woo Cho
    Department of Bioengineering, Hanyang University, Seoul 133 791, Republic of Korea
    Biochem Biophys Res Commun 340:573-82. 2006
    ..G-CSF treatment can enhance the efficacy of cellular cardiomyoplasty by ES cell-derived cardiomyocyte transplantation to treat myocardial infarction...
  47. ncbi request reprint HEK 293 cell suspension culture using fibronectin-adsorbed polymer nanospheres in serum-free medium
    Ju Hee Ryu
    Department of Chemical Engineering, Hanyang University, Seoul 133 791, Korea
    J Biomed Mater Res A 71:128-33. 2004
    ..This culture method may be useful for the large-scale suspension culture of various types of anchorage-dependent animal cells in serum-free medium...
  48. pmc Small-diameter blood vessels engineered with bone marrow-derived cells
    Seung Woo Cho
    Department of Chemical Engineering, Hanyang University, Seoul 133 791, Korea
    Ann Surg 241:506-15. 2005
    ..The objective of this study is to investigate if bone marrow-derived cells (BMCs) regenerate vascular tissues and improve patency in tissue-engineered small-diameter (internal diameter = 3 mm) vascular grafts...
  49. pmc Stemness evaluation of mesenchymal stem cells from placentas according to developmental stage: comparison to those from adult bone marrow
    Hwa Jung Sung
    Institute of Stem Cell Research, Korea University, Seoul, Korea
    J Korean Med Sci 25:1418-26. 2010
    ..In conclusions, hMSCs from placentas have different characteristics according to their developmental stage and express mesenchymal stemness potentials similar to those from adult human BMs...
  50. ncbi request reprint Renal tissue reconstitution by the implantation of renal segments on biodegradable polymer scaffolds
    Sang Soo Kim
    Department of Chemical Engineering, Hanyang University, Seoul, Korea
    Biotechnol Lett 25:1505-8. 2003
    ..Three-dimensional renal reconstructs were formed with glomeruli and tubules, showing a possibility of reconstituting renal structures by transplanting renal segments...
  51. ncbi request reprint Poly(lactide-co-glycolide)/hydroxyapatite composite scaffolds for bone tissue engineering
    Sang Soo Kim
    Department of Bioengineering, Hanyang University, Seoul 133 791, Republic of Korea
    Biomaterials 27:1399-409. 2006
    ..These results show that the biodegradable polymer/bioceramic composite scaffolds fabricated by the novel GF/PL method enhance bone regeneration compared with those fabricated by the conventional SC/PL method...
  52. ncbi request reprint Improvement of kidney failure with fetal kidney precursor cell transplantation
    Sang Soo Kim
    Department of Bioengineering, Hanyang University, Seoul, Korea
    Transplantation 83:1249-58. 2007
    ..Here, we show that the transplantation of fetal kidney precursor cells reconstitutes kidney tissues, reduces uremic symptoms, and provides life-saving metabolic support in kidney failure animal models...
  53. doi request reprint Acquisition of human alveolar bone-derived stromal cells using minimally irrigated implant osteotomy: in vitro and in vivo evaluations
    Jung Chul Park
    Department of Periodontology, Research Institute for Periodontal Regeneration, College of Dentistry, Yonsei University, Seoul, Korea
    J Clin Periodontol 39:495-505. 2012
    ..The aims of this study were to isolate human alveolar bone-derived stromal cells (hABCs) obtained during implant osteotomy, and to evaluate osteogenic differentiation capacity of hABCs...
  54. ncbi request reprint Comparison of osteogenic potential between apatite-coated poly(lactide-co-glycolide)/hydroxyapatite particulates and Bio-Oss
    Sang Soo Kim
    Department of Bioengineering, Hanyang University, Seoul 133 791, Korea
    Dent Mater J 27:368-75. 2008
    ..This study showed that a synthetic bone graft material, apatite-coated PLGA/HA particulates, had a comparable bone regeneration potential to the bovine-derived bone graft material, Bio-Oss...
  55. ncbi request reprint Controlled release of nerve growth factor from fibrin gel
    Suk Ho Bhang
    Department of Bioengineering, Hanyang University, Seoul 133 791, Korea
    J Biomed Mater Res A 80:998-1002. 2007
    ..This study demonstrates that fibrin gel can release NGF in a sustained, controlled manner and in a bioactive form...
  56. doi request reprint Enhanced bone formation by marrow-derived endothelial and osteogenic cell transplantation
    Sang Soo Kim
    Department of Bioengineering, Hanyang University, Seoul 133 791, Korea
    J Biomed Mater Res A 92:246-53. 2010
    ..8% +/- 2.5%), compared with transplantation of BMOCs alone (15.3% +/- 1.9%). These results demonstrate that the cotransplantation of BMECs enhances bone regeneration mediated by BMOC transplantation in osseous defects...
  57. ncbi request reprint Improvement of postnatal neovascularization by human embryonic stem cell derived endothelial-like cell transplantation in a mouse model of hindlimb ischemia
    Seung Woo Cho
    Department of Bioengineering, Hanyang University, Seoul, Korea
    Circulation 116:2409-19. 2007
    ..We established an efficient preparation method to obtain endothelial-like cells (ECs) from human embryonic stem cells (hESCs) and tested whether these hESC-ECs would show therapeutic potential for treatment of hindlimb ischemia...
  58. ncbi request reprint Efficacy of imatinib mesylate (STI571) in chronic neutrophilic leukemia with t(15;19): case report
    In Keun Choi
    Division of Oncology and Hematology, Department of Internal Medicine, College of Medicine, Korea University, Seoul, Korea
    Am J Hematol 77:366-9. 2004
    ..3) will be important in understanding the pathophysiology of CNL with a heterogeneous clinical course and the exploitation of the basic mechanisms of imatinib treatment...
  59. ncbi request reprint Kidney tissue reconstruction by fetal kidney cell transplantation: effect of gestation stage of fetal kidney cells
    Sang Soo Kim
    Department of Bioengineering, Hanyang University, 17 Haengdang dong, Seongdong Ku, Seoul 133 791, Korea
    Stem Cells 25:1393-401. 2007
    ..Disclosure of potential conflicts of interest is found at the end of this article...
  60. doi request reprint Porous poly(lactic-co-glycolic acid) microsphere as cell culture substrate and cell transplantation vehicle for adipose tissue engineering
    Sun Woong Kang
    Department of Chemical Engineering, Hanyang University, Seoul, Korea
    Tissue Eng Part C Methods 14:25-34. 2008
    ..Ex vivo cell expansion and transplantation using this system would improve the therapeutic efficacy of cells over the current methods used for tissue engineering...
  61. ncbi request reprint Enhancement of adipose tissue formation by implantation of adipogenic-differentiated preadipocytes
    Seung Woo Cho
    Department of Bioengineering, Hanyang University, Seoul 133 791, Republic of Korea
    Biochem Biophys Res Commun 345:588-94. 2006
    ....
  62. ncbi request reprint Enhancement of the osteogenic efficacy of osteoblast transplantation by the sustained delivery of basic fibroblast growth factor
    Min Sun Park
    Department of Chemical Engineering, Hanyang University, Seoul, Korea
    J Biomed Mater Res B Appl Biomater 79:353-9. 2006
    ..This combination therapy may have effective implications for bone regeneration in large bone defects in which extensive osteogenic cell migration and angiogenesis are required...
  63. doi request reprint Volume-stable adipose tissue formation by implantation of human adipose-derived stromal cells using solid free-form fabrication-based polymer scaffolds
    Tae Jin Lee
    Department of Bioengineering, Hanyang University, Seongdong Gu, Seoul, Republic of Korea
    Ann Plast Surg 70:98-102. 2013
    ..In addition, the mRNA expression of adipogenic genes was more extensive in the hADSC-PCL scaffold implants...
  64. doi request reprint Electroactive electrospun polyaniline/poly[(L-lactide)-co-(ε-caprolactone)] fibers for control of neural cell function
    Suk Ho Bhang
    Department of Bioengineering, Hanyang University, Seoul 133 791, Republic of Korea
    Macromol Biosci 12:402-11. 2012
    ..These results suggest that electroactive fibers may hold promise as a guidance scaffold for neuronal tissue engineering...
  65. ncbi request reprint The effect of cyclic strain on embryonic stem cell-derived cardiomyocytes
    So Jung Gwak
    Department of Chemical Engineering, Hanyang University, Seoul 133 791, Republic of Korea
    Biomaterials 29:844-56. 2008
    ..This study shows that the use of an elastic polymer scaffold designed to permit mechanical strain transduction as a cell transplantation vehicle significantly increases cardiomyogenesis of the implanted ESCs...
  66. doi request reprint The suggestion of a risk stratification system for febrile neutropenia in patients with hematologic disease
    Yong Park
    Division of Hematology and Oncology, Department of Internal Medicine, College of Medicine, Korea University, Seoul, Republic of Korea
    Leuk Res 34:294-300. 2010
    ..Further studies in prospective setting are needed for the validation of this model...
  67. ncbi request reprint Basic fibroblast growth factor promotes bone marrow stromal cell transplantation-mediated neural regeneration in traumatic brain injury
    Suk Ho Bhang
    Department of Bioengineering, Hanyang University, Seoul 133 791, Republic of Korea
    Biochem Biophys Res Commun 359:40-5. 2007
    ..This study demonstrates that bFGF significantly enhances histological and functional recovery when used in hBMSC transplantation therapy in TBI...
  68. ncbi request reprint Epirubicin, cisplatin, oral UFT, and leucovorin combination chemotherapy in advanced and metastatic esophageal cancer
    In Keun Choi
    Department of Internal Medicine, Division of Hematology Oncology, College of Medicine, Korea University, Seoul, Korea
    Med Oncol 24:33-7. 2007
    ..Therefore, we provided treatment with oral UFT and leucovorin instead of 5-FU PVI to improve convenience and catheter related complications...
  69. ncbi request reprint Effect of chondrocyte passage number on histological aspects of tissue-engineered cartilage
    Sun Woong Kang
    Department of Chemical Engineering, Hanyang University, Seoul 133 791, Korea
    Biomed Mater Eng 17:269-76. 2007
    ..e., glycosaminoglycans and type II collagen). The results of this study show that chondrocyte passage number is an important factor affecting the quality of cartilage tissue-engineered with the chondrocytes, and that chondrocytes...
  70. ncbi request reprint Delivery of basic fibroblast growth factor using heparin-conjugated fibrin for therapeutic angiogenesis
    Hee Seok Yang
    Department of Bioengineering, Hanyang University, Seoul, Republic of Korea
    Tissue Eng Part A 16:2113-9. 2010
    ..FGF2 delivery using HCF could be useful for therapeutic angiogenesis as HCF delivery enhances the therapeutic efficacy of FGF2...
  71. doi request reprint Evidence for in vivo growth potential and vascular remodeling of tissue-engineered artery
    Seung Woo Cho
    Department of Bioengineering, Hanyang University, Seoul, Korea
    Tissue Eng Part A 15:901-12. 2009
    ..This study demonstrates that the TEVGs with autologous BMCs and decellularized tissue matrices exhibit growth potential and vascular remodeling in vivo of tissue-engineered artery...
  72. doi request reprint Outcomes of multiple salvage chemotherapy for advanced gastric cancer: implications for clinical practice and trial design
    Yong Wha Moon
    Cancer Metastasis Research Center, Yonsei University College of Medicine, 250 Seongsanno, Seodaemun gu, Seoul, Korea
    Cancer Chemother Pharmacol 66:797-805. 2010
    ..We analyzed the natural history of advanced gastric cancer with sequential salvage chemotherapy following first-line treatment...
  73. ncbi request reprint Enhancement of in vivo bone regeneration efficacy of human mesenchymal stem cells
    Sun Woong Kang
    Department of Chemical Engineering, Hanyang University, Seoul 133 791, Korea
    J Microbiol Biotechnol 18:975-82. 2008
    ..The factorial experimental analysis showed that osteogenic differentiation of BMMSCs prior to transplantation has a stronger positive effect than the HAp scaffold on in vivo bone formation...
  74. doi request reprint The efficacy of human placenta as a source of the universal feeder in human and mouse pluripotent stem cell culture
    Yong Park
    Institute of Stem Cell Research, Korea University, Seoul, Korea
    Cell Reprogram 12:315-28. 2010
    ..In conclusion, the HPC feeder can efficiently support the undifferentiated propagation of hESCs, mESCs, and iPSCs, suggesting that human placenta may be a useful source of universal feeder cells for hESC, mESC, and iPSC culture...
  75. doi request reprint Open macroporous poly(lactic-co-glycolic Acid) microspheres as an injectable scaffold for cartilage tissue engineering
    Sun Woong Kang
    Department of Chemical Engineering, Hanyang University, Seoul 133 791, South Korea
    J Biomater Sci Polym Ed 20:399-409. 2009
    ..We conclude that an open macroporous PLGA microsphere scaffold may be useful in cartilage regeneration through minimally-invasive surgical procedures in orthopedic applications...
  76. ncbi request reprint The effect of microsphere degradation rate on the efficacy of polymeric microspheres as bulking agents: an 18-month follow-up study
    Sun Woong Kang
    Department of Chemical Engineering, Hanyang University, Seoul 133 791, South Korea
    J Biomed Mater Res B Appl Biomater 80:253-9. 2007
    ..These results show that the biodegradation rate of the bulking substance may be useful for controlling the duration of volume conservation of the induced hybrid tissue...
  77. ncbi request reprint Articular cartilage regeneration with microfracture and hyaluronic acid
    Sun Woong Kang
    Department of Chemical Engineering, Hanyang University, Seoul, Korea
    Biotechnol Lett 30:435-9. 2008
    ..The addition of transforming growth factor-beta3, an inducer of chondrogenic differentiation in mesenchymal stem cells, to the treatment with microfracture and hyaluronic acid did not significantly benefit cartilage regeneration...
  78. ncbi request reprint Apatite-coated poly(lactic-co-glycolic acid) microspheres as an injectable scaffold for bone tissue engineering
    Sun Woong Kang
    Department of Chemical Engineering, Hanyang University, Seoul 133 791, Korea
    J Biomed Mater Res A 85:747-56. 2008
    ..This scaffold may be useful for bone regeneration through minimally invasive surgical procedures in orthopedic applications...
  79. ncbi request reprint Reduced dose of imatinib for patients with chronic myeloid leukemia and low body surface area
    Seh Jong Park
    Department of Internal Medicine, Division of Hematology Oncology, College of Medicine, Korea University, Seoul, Korea
    Acta Haematol 118:219-21. 2007
  80. ncbi request reprint Human placenta-derived feeders support prolonged undifferentiated propagation of a human embryonic stem cell line, SNUhES3: comparison with human bone marrow-derived feeders
    Seok Jin Kim
    Institute of Korea, University Stem Cell Research, Seoul, Korea
    Stem Cells Dev 16:421-8. 2007
    ..Thus, placenta-derived feeders are more efficient for the long-term in vitro culture of human ES cells than bone marrow-derived feeders suggesting the possible role of placenta as a source for human cell-derived feeders...
  81. ncbi request reprint Additive effect of endothelial progenitor cell mobilization and bone marrow mononuclear cell transplantation on angiogenesis in mouse ischemic limbs
    Oju Jeon
    Department of Chemical Engineering, Hanyang University, 17 Haengdang dong, Seongdong Gu, Seoul, 133 791, Korea
    J Biomed Sci 14:323-30. 2007
    ..This study demonstrates that the combination therapy of BMMNC transplantation and EPC mobilization potentiates the angiogenic efficacy of either single therapy in mouse limb ischemia models...
  82. doi request reprint The effect of the delivery carrier on the quality of bone formed via bone morphogenetic protein-2
    Wan Geun La
    School of Chemical and Biological Engineering, Seoul National University, Seoul, Korea
    Artif Organs 36:642-7. 2012
    ..This study shows that a BMP-2 delivery carrier can modulate the quality of bone regenerated via BMP-2 delivery...
  83. doi request reprint Enhancement of human peripheral blood mononuclear cell transplantation-mediated bone formation
    Hee Seok Yang
    Department of Bioengineering, Hanyang University, Seoul, Republic of Korea
    Cell Transplant 20:1445-52. 2011
    ..This study provides a method to enhance human PBMNC transplantation-mediated bone formation...
  84. pmc Clinical factors related to suspected second primary lung cancer development in patients with head and neck cancer
    Eui Bae Kim
    Division of Oncology Hematology, Department of Internal Medicine, Korea University College of Medicine, Seoul, Korea
    Cancer Res Treat 40:178-83. 2008
    ....
  85. doi request reprint Extrinsic nitric oxide donor partially reverses arginine deiminase induced cell growth inhibition through NFkappaB and Bcl-X L
    Jae Hong Seo
    Division of Medical Oncology, Department of Internal Medicine, College of Medicine, Korea University, Seoul, South Korea
    Invest New Drugs 26:277-82. 2008
    ..In conclusion, we suggest that there might be an association between reversal of cell growth inhibition by extrinsic NO donor with Bcl-X L and NFkappaB expression in ADI-treated Ramos cell...
  86. doi request reprint Long-term delivery enhances in vivo osteogenic efficacy of bone morphogenetic protein-2 compared to short-term delivery
    Oju Jeon
    Department of Chemical Engineering, Hanyang University, Seoul 133 791, Republic of Korea
    Biochem Biophys Res Commun 369:774-80. 2008
    ..5-fold greater calcium content, upon implantation into rat hind limb muscle. These results show that long-term delivery of BMP-2 enhances in vivo osteogenic efficacy of the protein compared to short-term delivery at an equivalent dose...
  87. ncbi request reprint Combined therapy with human cord blood cell transplantation and basic fibroblast growth factor delivery for treatment of myocardial infarction
    Seung Woo Cho
    Department of Bioengineering, Hanyang University, Seoul 133 791, Republic of Korea
    Eur J Heart Fail 9:974-85. 2007
    ..Transplanting cord blood-derived cells has been shown to augment neovascularization in ischaemic tissue...
  88. doi request reprint Clinical impact of renal biopsy on outcomes in elderly patients with nephrotic syndrome
    Hye Eun Yoon
    Department of Internal Medicine, Seoul St Mary s Hospital, College of Medicine, The Catholic University of Korea, Seocho Gu, Seoul, Korea
    Nephron Clin Pract 117:c20-7. 2011
    ..The number of elderly patients with nephrotic syndrome (NS) is increasing. This study aimed to assess the implications of renal biopsy on the outcomes in elderly patients with NS...
  89. doi request reprint Effect of nucleus pulposus cells having different phenotypes on chondrogenic differentiation of adipose-derived stromal cells in a coculture system using porous membranes
    Eun Hee Choi
    Department of Biomedical Science, CHA University, Seoul, Korea
    Tissue Eng Part A 17:2445-51. 2011
    ..Further, the phenotype of cocultured NP cells significantly influences the extent of ASC differentiation...
  90. doi request reprint Poly(lactic-co-glycolic acid) nanosphere as a vehicle for gene delivery to human cord blood-derived mesenchymal stem cells: comparison with polyethylenimine
    So Jung Gwak
    Department of Chemical Engineering, Hanyang University, Seoul, 133 791, Korea
    Biotechnol Lett 30:1177-82. 2008
    ..We conclude that PLGA nanospheres have potential as gene delivery vehicles for use in gene therapy for diseases in which a long-term therapeutic gene expression regimen is necessary...
  91. pmc CpG methylation at GATA elements in the regulatory region of CCR3 positively correlates with CCR3 transcription
    Tae Gi Uhm
    Division of Molecular and Life Sciences, College of Science and Technology, Hanyang University, Ansan 426 791, Korea
    Exp Mol Med 44:268-80. 2012
    ..These results suggest that methylation of CpG sites at the GATA elements in the regulatory regions fine-tunes CCR3 transcription...
  92. doi request reprint Apatite-coated collagen scaffold for bone morphogenetic protein-2 delivery
    Hee Seok Yang
    Department of Bioengineering, Hanyang University, Seoul, Republic of Korea
    Tissue Eng Part A 17:2153-64. 2011
    ..This study shows that simple apatite coating of a collagen scaffold results in a BMP-2 carrier that renders long-term release of BMP-2 and dramatically enhances osteogenic efficacy...
  93. doi request reprint Predictors for progression in immunoglobulin A nephropathy with significant proteinuria
    Hyeon Seok Hwang
    Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul, Korea
    Nephrology (Carlton) 15:236-41. 2010
    ..Proteinuria is a primary factor requiring treatment in immunoglobulin (Ig)A nephropathy. The purpose of this study was to assess the relevance of treatment response and relapse of proteinuria with renal function decline...
  94. doi request reprint Suspension culture of mammalian cells using thermosensitive microcarrier that allows cell detachment without proteolytic enzyme treatment
    Hee Seok Yang
    Department of Bioengineering, Hanyang University, Seoul, Republic of Korea
    Cell Transplant 19:1123-32. 2010
    ..pNIPAAm-grafted microcarriers would be valuable to a variety of potential fields demanding a large amount of cells without cell damage, such as cell therapy, tissue engineering, and other biological and clinical applications...
  95. doi request reprint Phase II trial of concurrent radiation and weekly cisplatin followed by VIPD chemotherapy in newly diagnosed, stage IE to IIE, nasal, extranodal NK/T-Cell Lymphoma: Consortium for Improving Survival of Lymphoma study
    Seok Jin Kim
    Department of Pathology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea
    J Clin Oncol 27:6027-32. 2009
    ....
  96. pmc Regeneration of kidney tissue using in vitro cultured fetal kidney cells
    Sang Soo Kim
    Department of Bioengineering, Hanyang University, Seoul 133 791, Korea
    Exp Mol Med 40:361-9. 2008
    ..This result shows that in vitro culture of FKCs significantly affects the cell characteristics and in vivo tissue regenerative potential...
  97. ncbi request reprint The role of transforming growth factor-beta and bone morphogenetic protein with fibrin glue in healing of bone-tendon junction injury
    Hak Jun Kim
    Department of Orthopedic Surgery, Seoul Veterans Hospital, Seoul, Korea
    Connect Tissue Res 48:309-15. 2007
    ..BMP-2 in combination with fibrin glue accelerates healing in a bone-tendon injury and also improves the histological and biomechanical properties of the repair tissue so formed...
  98. doi request reprint In vitro cardiomyogenic differentiation of adipose-derived stromal cells using transforming growth factor-beta1
    So Jung Gwak
    Department of Chemical Engineering, Hanyang University, Seoul, Korea
    Cell Biochem Funct 27:148-54. 2009
    ..These results showed that TGF-beta1 induce ADSC cardiomyogenic differentiation in vitro, which could be useful for myocardial infarction stem cell therapy...
  99. doi request reprint Spinner-flask culture induces redifferentiation of de-differentiated chondrocytes
    Tae Jin Lee
    Department of Bioengineering, Hanyang University, Seoul, Republic of Korea
    Biotechnol Lett 33:829-36. 2011
    ..This system is easily scalable and could be feasible for clinical setting...
  100. doi request reprint Heparin-conjugated polyethylenimine for gene delivery
    Oju Jeon
    Department of Chemical Engineering, Hanyang University, 17 Haengdang dong, Seongdong Gu, Seoul 133 791, Republic of Korea
    J Control Release 132:236-42. 2008
    ..Taken together, heparin conjugation to PEI improves the in vivo gene transfection efficiency of PEI...
  101. ncbi request reprint Effects of cardiac patches engineered with bone marrow-derived mononuclear cells and PGCL scaffolds in a rat myocardial infarction model
    Hainan Piao
    Department of Cardiology, College of Medicine, Chungbuk National University, 62 Gaesin dong, Heungdeok Gu, Cheongju 361 763, Korea
    Biomaterials 28:641-9. 2007
    ..PGCL scaffolding can be considered as an effective treatment alternative in MI-induced advanced HF...