Il Yup Chung

Summary

Affiliation: Hanyang University
Country: Korea

Publications

  1. ncbi Genetic effect of CysLTR2 polymorphisms on its mRNA synthesis and stabilization
    Jeong Ah Shin
    Genome Research Center for Allergy and Respiratory Diseases, Soonchunhyang University Bucheon Hospital, 1174, Jung Dong, Wonmi Ku, Bucheon, Gyeonggi Do, 420 767, Korea
    BMC Med Genet 10:106. 2009
  2. ncbi Eotaxin and monocyte chemotactic protein-3 use different modes of action
    Il Yup Chung
    Department of Biochemistry and Molecular Biology, Hanyang University, Ansan, Kyunggi Do, Republic of Korea
    Biochem Biophys Res Commun 314:646-53. 2004
  3. ncbi Effect of single nucleotide polymorphisms within the interleukin-4 promoter on aspirin intolerance in asthmatics and interleukin-4 promoter activity
    Byung Soo Kim
    Division of Molecular and Life Sciences, College of Science and Technology, Hanyang University, Sangrok Ku, Ansan, Gyeonggi Do, Korea
    Pharmacogenet Genomics 20:748-58. 2010
  4. ncbi Regulation of functional phenotypes of cord blood derived eosinophils by gamma-secretase inhibitor
    Jin Hyun Kang
    Division of Molecular and Life Sciences, College of Science and Technology, Hanyang University, Ansan, South Korea
    Am J Respir Cell Mol Biol 37:571-7. 2007
  5. ncbi Eosinophilic differentiation is promoted by blockage of Notch signaling with a gamma-secretase inhibitor
    Jin Hyun Kang
    Division of Molecular and Life Sciences, College of Science and Technology, Hanyang University, Ansan, South Korea
    Eur J Immunol 35:2982-90. 2005
  6. ncbi The phosphoinositide-3-kinase/Akt pathway mediates the transient increase in Nanog expression during differentiation of F9 cells
    Jung Sun Kim
    Hanyang University, Ansan, Korea
    Arch Pharm Res 33:1117-25. 2010
  7. ncbi A parallel signal-transduction pathway for eotaxin- and interleukin-5-induced eosinophil shape change
    Eun Nam Choi
    Department of Biochemistry and Molecular Biology, Hanyang University, Ansan, South Korea
    Immunology 108:245-56. 2003
  8. ncbi A single nucleotide polymorphism on the promoter of eotaxin1 associates with its mRNA expression and asthma phenotypes
    Hun Soo Chang
    Division of Molecular and Life Sciences, Hanyang University, Ansan, Gyeonggi Do, Korea
    J Immunol 174:1525-31. 2005
  9. ncbi The crucial role of GATA-1 in CCR3 gene transcription: modulated balance by multiple GATA elements in the CCR3 regulatory region
    Byung Soo Kim
    Division of Molecular and Life Sciences, College of Science and Technology, Hanyang University, Ansan, South Korea
    J Immunol 185:6866-75. 2010
  10. ncbi Eosinophil development, regulation of eosinophil-specific genes, and role of eosinophils in the pathogenesis of asthma
    Tae Gi Uhm
    Division of Molecular and Life Sciences, College of Science and Technology, Hanyang University, Ansan, Korea
    Allergy Asthma Immunol Res 4:68-79. 2012

Collaborators

  • Hyemyung Seo
  • Choon Sik Park
  • Hyoung Doo Shin
  • An Soo Jang
  • Bong Geun Chung
  • Soon Young Shin
  • Young Mok Lee
  • Key-Sun Kim
  • Inseon S Choi
  • Hae Sim Park
  • Sang Heon Cho
  • Jin Hyun Kang
  • Byung Soo Kim
  • Tae Gi Uhm
  • Hun Soo Chang
  • Byung Lae Park
  • Soo Taek Uh
  • June Hyuk Lee
  • Jong Sook Park
  • Se Min Park
  • Jung Sun Kim
  • Sung Woo Park
  • Su Hwan Kim
  • Mi Kyeong Kim
  • Jeong Ah Shin
  • Taiyoun Rhim
  • Da Hye Lee
  • Eun Nam Choi
  • Jae Min Chung
  • Chang Hoon Woo
  • Jae Young Lee
  • Cheon Soo Hong
  • Sin Hwa Lee
  • Jiha Kim
  • Seol Kyoung Lee
  • Byoung Whui Choi
  • Gune Il Lim
  • Key Hyun Nam
  • Ji Hyun Kim
  • Se-Min Park
  • Yong-Hoon Kim
  • Yong Hoon Kim
  • June-Hyuk Lee
  • Hai Joong Kim
  • Jong Soo Lee
  • Jung Il Cho
  • Tai Youn Rhim
  • Soo-Taek Uh
  • Jin Woo Shin
  • Sang Jun Park
  • Do Jin Kim
  • Moon Kyung Choi
  • Jai Soung Park
  • Seog Beom Yoon
  • Dong Tak Jeong
  • Toshihiko Saeki
  • Jae-Hong Kim
  • Seog-Beom Yoon
  • Jae Hong Kim
  • Chang-Hoon Woo

Detail Information

Publications16

  1. ncbi Genetic effect of CysLTR2 polymorphisms on its mRNA synthesis and stabilization
    Jeong Ah Shin
    Genome Research Center for Allergy and Respiratory Diseases, Soonchunhyang University Bucheon Hospital, 1174, Jung Dong, Wonmi Ku, Bucheon, Gyeonggi Do, 420 767, Korea
    BMC Med Genet 10:106. 2009
    ..We investigated the genetic effects of the SNPs and haplotypes on the expression of the CysLTR2 gene...
  2. ncbi Eotaxin and monocyte chemotactic protein-3 use different modes of action
    Il Yup Chung
    Department of Biochemistry and Molecular Biology, Hanyang University, Ansan, Kyunggi Do, Republic of Korea
    Biochem Biophys Res Commun 314:646-53. 2004
    ..These results suggest that the two N-terminal motifs of eotaxin must cooperate with other regions to successfully bind and activate CCR3...
  3. ncbi Effect of single nucleotide polymorphisms within the interleukin-4 promoter on aspirin intolerance in asthmatics and interleukin-4 promoter activity
    Byung Soo Kim
    Division of Molecular and Life Sciences, College of Science and Technology, Hanyang University, Sangrok Ku, Ansan, Gyeonggi Do, Korea
    Pharmacogenet Genomics 20:748-58. 2010
    ..The objective of the study was to examine the influence of single nucleotide polymorphisms (SNPs) in IL-4 gene on aspirin hypersensitivity in asthmatics at the genetic and molecular levels...
  4. ncbi Regulation of functional phenotypes of cord blood derived eosinophils by gamma-secretase inhibitor
    Jin Hyun Kang
    Division of Molecular and Life Sciences, College of Science and Technology, Hanyang University, Ansan, South Korea
    Am J Respir Cell Mol Biol 37:571-7. 2007
    ..GSI has therapeutic potential for eosinophilic inflammatory diseases, such as asthma...
  5. ncbi Eosinophilic differentiation is promoted by blockage of Notch signaling with a gamma-secretase inhibitor
    Jin Hyun Kang
    Division of Molecular and Life Sciences, College of Science and Technology, Hanyang University, Ansan, South Korea
    Eur J Immunol 35:2982-90. 2005
    ..Our data suggest that Notch signaling may modulate eosinophil migration at the mature stage as well as inhibit eosinophil differentiation...
  6. ncbi The phosphoinositide-3-kinase/Akt pathway mediates the transient increase in Nanog expression during differentiation of F9 cells
    Jung Sun Kim
    Hanyang University, Ansan, Korea
    Arch Pharm Res 33:1117-25. 2010
    ..Thus, Nanog expression appears to be differently regulated by the PI3K/Akt pathway depending on differentiation stage...
  7. ncbi A parallel signal-transduction pathway for eotaxin- and interleukin-5-induced eosinophil shape change
    Eun Nam Choi
    Department of Biochemistry and Molecular Biology, Hanyang University, Ansan, South Korea
    Immunology 108:245-56. 2003
    ..Collectively, two eosinophil-selective cytokines/chemokines probably regulate eosinophil shape change via a largely overlapping signalling pathway, with involvement of PKC restricted to the IL-5 signal alone...
  8. ncbi A single nucleotide polymorphism on the promoter of eotaxin1 associates with its mRNA expression and asthma phenotypes
    Hun Soo Chang
    Division of Molecular and Life Sciences, Hanyang University, Ansan, Gyeonggi Do, Korea
    J Immunol 174:1525-31. 2005
    ..Our data suggest that the EOT-384A>G SNP participates in the regulation of eotaxin1 expression by providing a potential binding site for a repressor, and that the ANOVA of EOT-384A>G may predict asthma phenotypes...
  9. ncbi The crucial role of GATA-1 in CCR3 gene transcription: modulated balance by multiple GATA elements in the CCR3 regulatory region
    Byung Soo Kim
    Division of Molecular and Life Sciences, College of Science and Technology, Hanyang University, Ansan, South Korea
    J Immunol 185:6866-75. 2010
    ..These data suggest that GATA-1 controls CCR3 transcription by interacting dynamically with the multiple GATA sites in the regulatory region of the CCR3 gene...
  10. ncbi Eosinophil development, regulation of eosinophil-specific genes, and role of eosinophils in the pathogenesis of asthma
    Tae Gi Uhm
    Division of Molecular and Life Sciences, College of Science and Technology, Hanyang University, Ansan, Korea
    Allergy Asthma Immunol Res 4:68-79. 2012
    ....
  11. ncbi Mucin (MUC5AC) expression by lung epithelial cells cultured in a microfluidic gradient device
    Su Hwan Kim
    Department of Bionano Engineering, Hanyang University, Ansan, Korea
    Electrophoresis 32:254-60. 2011
    ..Therefore, this microfluidic gradient device could be a potentially useful tool for regulating the mucin expression of lung epithelial cells exposed to chemokine gradient profiles...
  12. ncbi The purification and characterization of a Bacillus stearothermophilus methionine aminopeptidase (MetAP)
    Jae Min Chung
    Department of Biochemistry and Molecular Biology, Hanyang University, Sa-1-dong 1271, Ansan, Kyunggi-do, 425-791, Korea
    J Biochem Mol Biol 35:228-35. 2002
    ..0 mM and 1.7 mmol/min/mg, respectively. The B. stearothermophilus MetAP was completely inactivated by EDTA and required Co(2+) ion(s) for activation, suggesting the metal dependence of this enzyme..
  13. ncbi Genetic effect of CCR3 and IL5RA gene polymorphisms on eosinophilia in asthmatic patients
    June Hyuk Lee
    Genome Research Center for Allergy and Respiratory Diseases, Soonchunhyang University Bucheon Hospital, Gyeonggi Do, Korea
    J Allergy Clin Immunol 120:1110-7. 2007
    ..Eosinophilic infiltration and peripheral blood eosinophilia in asthma require the cooperation of eosinophil-specific cytokines and chemokines and their receptors...
  14. ncbi Interferon-gamma inhibits in vitro mobilization of eosinophils by interleukin-5
    Choon-Sik Park
    Genome Research Center for Asthma and Allergic Diseases, Division of Allergy and Respiratory Medicine, Soonchunhyang University Hospital, Seoul and Bucheon, Korea
    Int Arch Allergy Immunol 136:295-302. 2005
    ..CONCLUSIONS: Collectively, IFN-gamma may attenuate eosinophilic inflammation by directly negating eosinophil mobilization...
  15. ncbi Association of interleukin-5 and eotaxin with acute exacerbation of asthma
    Sung Woo Park
    Asthma and Allergy Research Group, Soonchunhyang University Hospital, Bucheon, Korea
    Int Arch Allergy Immunol 131:283-90. 2003
    ..Interrelation between these cytokines is expected to occur in acute exacerbation of asthma. Thus, we evaluated the relevance of interaction between eotaxin and IL-5 in the airway inflammation of acute exacerbation...
  16. ncbi Eotaxin induces migration of RBL-2H3 mast cells via a Rac-ERK-dependent pathway
    Chang Hoon Woo
    Graduate School of Biotechnology, Korea University, 5 1 Anam dong, Sungbuk Gu, Seoul 136 701, South Korea
    Biochem Biophys Res Commun 298:392-7. 2002
    ..It thus appears that Rac1 acts upstream of ERK to signal chemotaxis in these cells, and that a Rac-ERK-dependent cascade mediates the eotaxin-induced chemotactic motility of RBL-2H3 mast cells...