Pil Seok Chae

Summary

Affiliation: Hanyang University
Country: Korea

Publications

  1. ncbi request reprint New ganglio-tripod amphiphiles (TPAs) for membrane protein solubilization and stabilization: implications for detergent structure-property relationships
    Pil Seok Chae
    Department of Bionanotechnology, Hanyang University, Ansan, 426 791, Korea
    Org Biomol Chem 12:8480-7. 2014
  2. ncbi request reprint Adamantane-based amphiphiles (ADAs) for membrane protein study: importance of a detergent hydrophobic group in membrane protein solubilisation
    Pil Seok Chae
    Department of Bionanotechnology, Hanyang University, Ansan, 426 791, Korea
    Chem Commun (Camb) 50:12300-3. 2014
  3. pmc Novel tripod amphiphiles for membrane protein analysis
    Pil Seok Chae
    Department of Bionano Engineering, Hanyang University Ansan, 426 791 Korea, Fax 81 31 436 8146
    Chemistry 19:15645-51. 2013
  4. pmc Hydrophobic variations of N-oxide amphiphiles for membrane protein manipulation: importance of non-hydrocarbon groups in the hydrophobic portion
    Pil Seok Chae
    Department of Bionano Engineering, Hanyang University Ansan, 426 791 Korea, Fax 81 31 436 8146
    Chem Asian J 9:110-6. 2014
  5. pmc Hydrophobic variants of ganglio-tripod amphiphiles for membrane protein manipulation
    Pil Seok Chae
    Department of Bionano Engineering, Hanyang University, Ansan 426 791, Republic of Korea Electronic address
    Biochim Biophys Acta 1838:278-86. 2014
  6. pmc A new class of amphiphiles bearing rigid hydrophobic groups for solubilization and stabilization of membrane proteins
    Pil Seok Chae
    Department of Bionano Engineering, Hanyang University, Ansan, 426 791 Korea
    Chemistry 18:9485-90. 2012
  7. pmc Carbohydrate-containing Triton X-100 analogues for membrane protein solubilization and stabilization
    Pil Seok Chae
    Department of Bionano Engineering, Hanyang University, Ansan, 426 791, Korea
    Mol Biosyst 9:626-9. 2013
  8. pmc Glucose-neopentyl glycol (GNG) amphiphiles for membrane protein study
    Pil Seok Chae
    Department of Bionano Engineering, Hanyang University, Ansan, 426 791, Korea
    Chem Commun (Camb) 49:2287-9. 2013
  9. ncbi request reprint Hemifluorinated maltose-neopentyl glycol (HF-MNG) amphiphiles for membrane protein stabilisation
    Kyung Ho Cho
    Department of Bionano Engineering, Hanyang University, 55 Hanyangdaehak ro, Sangnok gu, Ansan, 426 791, Korea
    Chembiochem 14:452-5. 2013
  10. ncbi request reprint Improved glucose-neopentyl glycol (GNG) amphiphiles for membrane protein solubilization and stabilization
    Kyung Ho Cho
    Department of Bionanotechnology, Hanyang University, Ansan, 426 791 Korea, Fax 81 31 436 8146
    Chem Asian J 9:632-8. 2014

Collaborators

Detail Information

Publications11

  1. ncbi request reprint New ganglio-tripod amphiphiles (TPAs) for membrane protein solubilization and stabilization: implications for detergent structure-property relationships
    Pil Seok Chae
    Department of Bionanotechnology, Hanyang University, Ansan, 426 791, Korea
    Org Biomol Chem 12:8480-7. 2014
    ..The current study combined with previous TPA studies enabled us to elaborate on a few detergent structure-property relationships that could provide useful guidelines for novel amphiphile design. ..
  2. ncbi request reprint Adamantane-based amphiphiles (ADAs) for membrane protein study: importance of a detergent hydrophobic group in membrane protein solubilisation
    Pil Seok Chae
    Department of Bionanotechnology, Hanyang University, Ansan, 426 791, Korea
    Chem Commun (Camb) 50:12300-3. 2014
    ..These agents were superior to conventional detergents, especially in terms of the membrane protein solubilisation efficiency, implying a new detergent structure-property relationship. ..
  3. pmc Novel tripod amphiphiles for membrane protein analysis
    Pil Seok Chae
    Department of Bionano Engineering, Hanyang University Ansan, 426 791 Korea, Fax 81 31 436 8146
    Chemistry 19:15645-51. 2013
    ....
  4. pmc Hydrophobic variations of N-oxide amphiphiles for membrane protein manipulation: importance of non-hydrocarbon groups in the hydrophobic portion
    Pil Seok Chae
    Department of Bionano Engineering, Hanyang University Ansan, 426 791 Korea, Fax 81 31 436 8146
    Chem Asian J 9:110-6. 2014
    ....
  5. pmc Hydrophobic variants of ganglio-tripod amphiphiles for membrane protein manipulation
    Pil Seok Chae
    Department of Bionano Engineering, Hanyang University, Ansan 426 791, Republic of Korea Electronic address
    Biochim Biophys Acta 1838:278-86. 2014
    ..Their efficacy rivals benchmark detergents heavily used today, such as n-dodecyl-β-d-maltoside. ..
  6. pmc A new class of amphiphiles bearing rigid hydrophobic groups for solubilization and stabilization of membrane proteins
    Pil Seok Chae
    Department of Bionano Engineering, Hanyang University, Ansan, 426 791 Korea
    Chemistry 18:9485-90. 2012
    ..The results show that the new amphiphile, "glyco-diosgenin" (GDN; see figure), confers enhanced stability to a variety of membrane proteins in solution relative to popular conventional detergents, such as dodecylmaltoside (DDM)...
  7. pmc Carbohydrate-containing Triton X-100 analogues for membrane protein solubilization and stabilization
    Pil Seok Chae
    Department of Bionano Engineering, Hanyang University, Ansan, 426 791, Korea
    Mol Biosyst 9:626-9. 2013
    ..This study introduces a class of easy-to-synthesize amphiphiles, which are designated CGT (Chae's Glyco-Triton) detergents. Some of the agents are well suited for membrane protein solubilization and stabilization...
  8. pmc Glucose-neopentyl glycol (GNG) amphiphiles for membrane protein study
    Pil Seok Chae
    Department of Bionano Engineering, Hanyang University, Ansan, 426 791, Korea
    Chem Commun (Camb) 49:2287-9. 2013
    ..These amphiphiles display promising behavior for membrane proteins, as demonstrated recently by the high resolution structure of a sodium-pumping pyrophosphatase reported by Kellosalo et al. (Science, 2012, 337, 473)...
  9. ncbi request reprint Hemifluorinated maltose-neopentyl glycol (HF-MNG) amphiphiles for membrane protein stabilisation
    Kyung Ho Cho
    Department of Bionano Engineering, Hanyang University, 55 Hanyangdaehak ro, Sangnok gu, Ansan, 426 791, Korea
    Chembiochem 14:452-5. 2013
    ..Such amphiphiles are attractive as tools for membrane science because of their ease of preparation and structure variation...
  10. ncbi request reprint Improved glucose-neopentyl glycol (GNG) amphiphiles for membrane protein solubilization and stabilization
    Kyung Ho Cho
    Department of Bionanotechnology, Hanyang University, Ansan, 426 791 Korea, Fax 81 31 436 8146
    Chem Asian J 9:632-8. 2014
    ..Furthermore, a detergent structure-property relationship that could serve as a useful guideline for the design of novel amphiphiles is discussed. ..
  11. ncbi request reprint Fabrication of monodisperse liposomes-in-microgel hybrid microparticles in capillary-based microfluidic devices
    Eun Seon Jeong
    Department of BioNano Technology, Hanyang University, Ansan, Gyeonggi do 426 791, Republic of Korea
    Colloids Surf B Biointerfaces 123:339-44. 2014
    ....