Ok Nam Bae

Summary

Affiliation: Hanyang University
Country: Korea

Publications

  1. doi request reprint Targeting von Willebrand factor as a novel anti-platelet therapy; application of ARC1779, an Anti-vWF aptamer, against thrombotic risk
    Ok Nam Bae
    College of Pharmacy, Hanyang University, Gyeonggi Do, Korea
    Arch Pharm Res 35:1693-9. 2012
  2. ncbi request reprint Antithrombotic activity of LB30057, a newly synthesized direct thrombin inhibitor
    Kyu Tae Kang
    Research Institute of Pharmaceutical Sciences, College of Pharmacy, Seoul National University, Seoul, Korea
    Thromb Haemost 89:104-11. 2003
  3. doi request reprint Procoagulant and prothrombotic activation of human erythrocytes by phosphatidic acid
    Ji Yoon Noh
    College of Pharmacy, Seoul National Univ, Seoul 151 742, Korea
    Am J Physiol Heart Circ Physiol 299:H347-55. 2010
  4. doi request reprint Silver nanoparticles enhance thrombus formation through increased platelet aggregation and procoagulant activity
    Eun Ah Jun
    College of Pharmacy, Seoul National University, Shinrim dong San 56 1, Gwanak ku, Seoul, Korea
    Nanotoxicology 5:157-67. 2011
  5. ncbi request reprint Enhancement of platelet aggregation and thrombus formation by arsenic in drinking water: a contributing factor to cardiovascular disease
    Moo Yeol Lee
    College of Pharmacy, Seoul National University, Seoul, 151 742, Korea
    Toxicol Appl Pharmacol 179:83-8. 2002
  6. doi request reprint A naphthoquinone derivative can induce anemia through phosphatidylserine exposure-mediated erythrophagocytosis
    Ji Yoon Noh
    College of Pharmacy, Seoul National University, Seoul, Korea
    J Pharmacol Exp Ther 333:414-20. 2010
  7. ncbi request reprint Lysophosphatidic acid induces thrombogenic activity through phosphatidylserine exposure and procoagulant microvesicle generation in human erythrocytes
    Seung Min Chung
    College of Pharmacy, Seoul National University, Seoul 151 742, Korea
    Arterioscler Thromb Vasc Biol 27:414-21. 2007
  8. doi request reprint Novel antiplatelet activity of protocatechuic acid through the inhibition of high shear stress-induced platelet aggregation
    Keunyoung Kim
    College of Pharmacy, Seoul National University, Seoul, Korea
    J Pharmacol Exp Ther 343:704-11. 2012
  9. ncbi request reprint LB30057 inhibits platelet aggregation and vascular relaxation induced by thrombin
    Byoung In Jung
    Research Institute of Pharmaceutical Sciences, College of Pharmacy, Seoul National University, Seoul 151 742, Korea
    Arch Pharm Res 25:879-84. 2002
  10. ncbi request reprint Lead-induced procoagulant activation of erythrocytes through phosphatidylserine exposure may lead to thrombotic diseases
    Jung Hun Shin
    College of Pharmacy, Seoul National University, Seoul 151 742, Korea
    Chem Res Toxicol 20:38-43. 2007

Collaborators

  • Jin Ho Chung
  • Moo Yeol Lee
  • Sang Koo Lee
  • Young Min Bae
  • Jin Young Lee
  • Yi Sook Jung
  • Kyung Min Lim
  • Ji Yoon Noh
  • Keunyoung Kim
  • Seung Min Chung
  • Seojin Kang
  • So Youn Kwon
  • Eun Ah Jun
  • Kyu Tae Kang
  • Byoung In Jung
  • Jung Hun Shin
  • Young Jun Shin
  • Jung Eun Koo
  • Eun Sun Kim
  • In Chul Kim
  • SeungJin Bae
  • Jae Hyuk Kwon
  • Young Ah Kang
  • Jung Min Park
  • Hyang Hwa Woo
  • Ka Young Chung
  • Kyu Hyuck Chung
  • Kyung Mi Joo
  • Sue Shin
  • Jong Sook Park

Detail Information

Publications20

  1. doi request reprint Targeting von Willebrand factor as a novel anti-platelet therapy; application of ARC1779, an Anti-vWF aptamer, against thrombotic risk
    Ok Nam Bae
    College of Pharmacy, Hanyang University, Gyeonggi Do, Korea
    Arch Pharm Res 35:1693-9. 2012
    ..Here, we will discuss the potential benefits of targeting vWF as a novel antiplatelet therapy, providing an insight into the role of vWF in increased thrombotic risk...
  2. ncbi request reprint Antithrombotic activity of LB30057, a newly synthesized direct thrombin inhibitor
    Kyu Tae Kang
    Research Institute of Pharmaceutical Sciences, College of Pharmacy, Seoul National University, Seoul, Korea
    Thromb Haemost 89:104-11. 2003
    ....
  3. doi request reprint Procoagulant and prothrombotic activation of human erythrocytes by phosphatidic acid
    Ji Yoon Noh
    College of Pharmacy, Seoul National Univ, Seoul 151 742, Korea
    Am J Physiol Heart Circ Physiol 299:H347-55. 2010
    ..In conclusion, these results suggest that PA can induce thrombogenic activities in erythrocytes through PS exposure, which can increase thrombus formation and ultimately contribute to the development of cardiovascular diseases...
  4. doi request reprint Silver nanoparticles enhance thrombus formation through increased platelet aggregation and procoagulant activity
    Eun Ah Jun
    College of Pharmacy, Seoul National University, Shinrim dong San 56 1, Gwanak ku, Seoul, Korea
    Nanotoxicology 5:157-67. 2011
    ....
  5. ncbi request reprint Enhancement of platelet aggregation and thrombus formation by arsenic in drinking water: a contributing factor to cardiovascular disease
    Moo Yeol Lee
    College of Pharmacy, Seoul National University, Seoul, 151 742, Korea
    Toxicol Appl Pharmacol 179:83-8. 2002
    ....
  6. doi request reprint A naphthoquinone derivative can induce anemia through phosphatidylserine exposure-mediated erythrophagocytosis
    Ji Yoon Noh
    College of Pharmacy, Seoul National University, Seoul, Korea
    J Pharmacol Exp Ther 333:414-20. 2010
    ..In conclusion, these results suggest that betaL-induced anemia might be mediated through the PS exposure and subsequent erythrophagocytosis, providing novel insight into the drug-induced anemia...
  7. ncbi request reprint Lysophosphatidic acid induces thrombogenic activity through phosphatidylserine exposure and procoagulant microvesicle generation in human erythrocytes
    Seung Min Chung
    College of Pharmacy, Seoul National University, Seoul 151 742, Korea
    Arterioscler Thromb Vasc Biol 27:414-21. 2007
    ....
  8. doi request reprint Novel antiplatelet activity of protocatechuic acid through the inhibition of high shear stress-induced platelet aggregation
    Keunyoung Kim
    College of Pharmacy, Seoul National University, Seoul, Korea
    J Pharmacol Exp Ther 343:704-11. 2012
    ..Collectively, these results suggest that PCA may be a novel antiplatelet agent that can prevent thrombosis without increasing bleeding risks...
  9. ncbi request reprint LB30057 inhibits platelet aggregation and vascular relaxation induced by thrombin
    Byoung In Jung
    Research Institute of Pharmaceutical Sciences, College of Pharmacy, Seoul National University, Seoul 151 742, Korea
    Arch Pharm Res 25:879-84. 2002
    ..All these results suggest that LB30057 is a potent inhibitor of platelet aggregation and blood vessel relaxation induced by thrombin...
  10. ncbi request reprint Lead-induced procoagulant activation of erythrocytes through phosphatidylserine exposure may lead to thrombotic diseases
    Jung Hun Shin
    College of Pharmacy, Seoul National University, Seoul 151 742, Korea
    Chem Res Toxicol 20:38-43. 2007
    ..These data will provide new insights into the mechanism of lead-induced cardiovascular diseases...
  11. pmc Arsenic-induced dysfunction in relaxation of blood vessels
    Moo Yeol Lee
    College of Pharmacy, Seoul National University, Seoul, Korea
    Environ Health Perspect 111:513-7. 2003
    ..These data suggest that an impairment of vasomotor tone due to arsenite exposure may be a contributing factor in the development of cardiovascular disease...
  12. doi request reprint Vascular smooth muscle dysfunction and remodeling induced by ginsenoside Rg3, a bioactive component of ginseng
    Jin Young Lee
    College of Pharmacy, Seoul National University, Seoul 151 742, Korea
    Toxicol Sci 117:505-14. 2010
    ..These results suggest that Rg3 can induce the vascular smooth muscle dysfunction by disturbing Ca(2+) influx from the L-type Ca(2+) channel, ultimately leading to impaired vascular contractility and structural remodeling...
  13. pmc Emodin inhibits tonic tension through suppressing PKCδ-mediated inhibition of myosin phosphatase in rat isolated thoracic aorta
    Kyung Min Lim
    College of Pharmacy, Ewha Womans University, Seoul, Korea
    Br J Pharmacol 171:4300-10. 2014
    ..Despite a huge therapeutic potential, little is known about natural products targeting tonic tension and calcium sensitization...
  14. doi request reprint Dysfunction of vascular smooth muscle and vascular remodeling by simvastatin
    Seojin Kang
    College of Pharmacy, Seoul National University, Seoul 151 742, Korea
    Toxicol Sci 138:446-556. 2014
    ..Collectively, these results demonstrate that simvastatin can impair the normal vascular contractility by disturbing Ca²⁺ influx and RhoA activity, ultimately leading to apoptosis and structural remodeling...
  15. ncbi request reprint Arsenite-enhanced procoagulant activity through phosphatidylserine exposure in platelets
    Ok Nam Bae
    College of Pharmacy, Seoul National University, Korea
    Chem Res Toxicol 20:1760-8. 2007
    ....
  16. ncbi request reprint Temperature-dependent quinone cytotoxicity in platelets involves arylation
    Young Ah Kang
    Research Institute of Pharmaceutical Sciences, College of Pharmacy, Seoul National University, Seoul, Korea
    J Toxicol Environ Health A 65:1367-78. 2002
    ..This might be due to increased arylation capacity binding to cellular proteins as temperature rises. These data suggest that MEN-induced platelet cytotoxicity involves arylation that is temperature related...
  17. pmc Erythrophagocytosis of lead-exposed erythrocytes by renal tubular cells: possible role in lead-induced nephrotoxicity
    So Youn Kwon
    College of Pharmacy, Seoul National University, Seoul, Korea
    Environ Health Perspect 123:120-7. 2015
    ..Nephrotoxicity associated with lead poisoning has been frequently reported in epidemiological studies, but the underlying mechanisms have not been fully described...
  18. doi request reprint Suppression of skin inflammation in keratinocytes and acute/chronic disease models by caffeic acid phenethyl ester
    Kyung Min Lim
    College of Pharmacy, Ewha Womans University, Seoul, Korea
    Arch Dermatol Res 307:219-27. 2015
    ..Collectively, our results propose CAPE as a promising candidate for a novel topical drug for skin inflammatory diseases. ..
  19. doi request reprint Salsolinol, an endogenous neurotoxin, enhances platelet aggregation and thrombus formation
    Ok Nam Bae
    College of Pharmacy, Seoul National University, Shinrim dong San 56 1, Seoul 151 742, Korea
    Thromb Haemost 100:52-9. 2008
    ..These results suggest that salsolinol-enhanced platelet aggregation could be a possible contributing factor to the thrombotic events observed in Parkinson's disease and alcoholism...