Ok Nam Bae

Summary

Affiliation: Hanyang University
Country: Korea

Publications

  1. doi request reprint Targeting von Willebrand factor as a novel anti-platelet therapy; application of ARC1779, an Anti-vWF aptamer, against thrombotic risk
    Ok Nam Bae
    College of Pharmacy, Hanyang University, Gyeonggi Do, Korea
    Arch Pharm Res 35:1693-9. 2012
  2. ncbi request reprint Antithrombotic activity of LB30057, a newly synthesized direct thrombin inhibitor
    Kyu Tae Kang
    Research Institute of Pharmaceutical Sciences, College of Pharmacy, Seoul National University, Seoul, Korea
    Thromb Haemost 89:104-11. 2003
  3. ncbi request reprint Procoagulant and prothrombotic activation of human erythrocytes by phosphatidic acid
    Ji Yoon Noh
    College of Pharmacy, Seoul National Univ, Seoul 151 742, Korea
    Am J Physiol Heart Circ Physiol 299:H347-55. 2010
  4. doi request reprint Silver nanoparticles enhance thrombus formation through increased platelet aggregation and procoagulant activity
    Eun Ah Jun
    College of Pharmacy, Seoul National University, Shinrim dong San 56 1, Gwanak ku, Seoul, Korea
    Nanotoxicology 5:157-67. 2011
  5. ncbi request reprint Enhancement of platelet aggregation and thrombus formation by arsenic in drinking water: a contributing factor to cardiovascular disease
    Moo Yeol Lee
    College of Pharmacy, Seoul National University, Seoul, 151 742, Korea
    Toxicol Appl Pharmacol 179:83-8. 2002
  6. doi request reprint A naphthoquinone derivative can induce anemia through phosphatidylserine exposure-mediated erythrophagocytosis
    Ji Yoon Noh
    College of Pharmacy, Seoul National University, Seoul, Korea
    J Pharmacol Exp Ther 333:414-20. 2010
  7. ncbi request reprint Lysophosphatidic acid induces thrombogenic activity through phosphatidylserine exposure and procoagulant microvesicle generation in human erythrocytes
    Seung Min Chung
    College of Pharmacy, Seoul National University, Seoul 151 742, Korea
    Arterioscler Thromb Vasc Biol 27:414-21. 2007
  8. doi request reprint Novel antiplatelet activity of protocatechuic acid through the inhibition of high shear stress-induced platelet aggregation
    Keunyoung Kim
    College of Pharmacy, Seoul National University, Seoul, Korea
    J Pharmacol Exp Ther 343:704-11. 2012
  9. pmc Arsenic-induced dysfunction in relaxation of blood vessels
    Moo Yeol Lee
    College of Pharmacy, Seoul National University, Seoul, Korea
    Environ Health Perspect 111:513-7. 2003
  10. ncbi request reprint LB30057 inhibits platelet aggregation and vascular relaxation induced by thrombin
    Byoung In Jung
    Research Institute of Pharmaceutical Sciences, College of Pharmacy, Seoul National University, Seoul 151 742, Korea
    Arch Pharm Res 25:879-84. 2002

Collaborators

  • Jin Ho Chung
  • Sang Koo Lee
  • Young Min Bae
  • Jin Young Lee
  • Yi Sook Jung
  • Ji Yoon Noh
  • Seung Min Chung
  • Moo Yeol Lee
  • Kyung Min Lim
  • Keunyoung Kim
  • Seojin Kang
  • Kyu Tae Kang
  • Eun Ah Jun
  • Byoung In Jung
  • Jung Hun Shin
  • In Chul Kim
  • Young Ah Kang
  • Hyang Hwa Woo
  • Ka Young Chung
  • Kyu Hyuck Chung
  • Jong Sook Park
  • Sue Shin
  • Kyung Mi Joo
  • Ji Sun Yang
  • Byung In Jung
  • Hyomin Lee
  • Jung Duck Park

Detail Information

Publications17

  1. doi request reprint Targeting von Willebrand factor as a novel anti-platelet therapy; application of ARC1779, an Anti-vWF aptamer, against thrombotic risk
    Ok Nam Bae
    College of Pharmacy, Hanyang University, Gyeonggi Do, Korea
    Arch Pharm Res 35:1693-9. 2012
    ..Here, we will discuss the potential benefits of targeting vWF as a novel antiplatelet therapy, providing an insight into the role of vWF in increased thrombotic risk...
  2. ncbi request reprint Antithrombotic activity of LB30057, a newly synthesized direct thrombin inhibitor
    Kyu Tae Kang
    Research Institute of Pharmaceutical Sciences, College of Pharmacy, Seoul National University, Seoul, Korea
    Thromb Haemost 89:104-11. 2003
    ....
  3. ncbi request reprint Procoagulant and prothrombotic activation of human erythrocytes by phosphatidic acid
    Ji Yoon Noh
    College of Pharmacy, Seoul National Univ, Seoul 151 742, Korea
    Am J Physiol Heart Circ Physiol 299:H347-55. 2010
    ..In conclusion, these results suggest that PA can induce thrombogenic activities in erythrocytes through PS exposure, which can increase thrombus formation and ultimately contribute to the development of cardiovascular diseases...
  4. doi request reprint Silver nanoparticles enhance thrombus formation through increased platelet aggregation and procoagulant activity
    Eun Ah Jun
    College of Pharmacy, Seoul National University, Shinrim dong San 56 1, Gwanak ku, Seoul, Korea
    Nanotoxicology 5:157-67. 2011
    ....
  5. ncbi request reprint Enhancement of platelet aggregation and thrombus formation by arsenic in drinking water: a contributing factor to cardiovascular disease
    Moo Yeol Lee
    College of Pharmacy, Seoul National University, Seoul, 151 742, Korea
    Toxicol Appl Pharmacol 179:83-8. 2002
    ....
  6. doi request reprint A naphthoquinone derivative can induce anemia through phosphatidylserine exposure-mediated erythrophagocytosis
    Ji Yoon Noh
    College of Pharmacy, Seoul National University, Seoul, Korea
    J Pharmacol Exp Ther 333:414-20. 2010
    ..In conclusion, these results suggest that betaL-induced anemia might be mediated through the PS exposure and subsequent erythrophagocytosis, providing novel insight into the drug-induced anemia...
  7. ncbi request reprint Lysophosphatidic acid induces thrombogenic activity through phosphatidylserine exposure and procoagulant microvesicle generation in human erythrocytes
    Seung Min Chung
    College of Pharmacy, Seoul National University, Seoul 151 742, Korea
    Arterioscler Thromb Vasc Biol 27:414-21. 2007
    ....
  8. doi request reprint Novel antiplatelet activity of protocatechuic acid through the inhibition of high shear stress-induced platelet aggregation
    Keunyoung Kim
    College of Pharmacy, Seoul National University, Seoul, Korea
    J Pharmacol Exp Ther 343:704-11. 2012
    ..Collectively, these results suggest that PCA may be a novel antiplatelet agent that can prevent thrombosis without increasing bleeding risks...
  9. pmc Arsenic-induced dysfunction in relaxation of blood vessels
    Moo Yeol Lee
    College of Pharmacy, Seoul National University, Seoul, Korea
    Environ Health Perspect 111:513-7. 2003
    ..These data suggest that an impairment of vasomotor tone due to arsenite exposure may be a contributing factor in the development of cardiovascular disease...
  10. ncbi request reprint LB30057 inhibits platelet aggregation and vascular relaxation induced by thrombin
    Byoung In Jung
    Research Institute of Pharmaceutical Sciences, College of Pharmacy, Seoul National University, Seoul 151 742, Korea
    Arch Pharm Res 25:879-84. 2002
    ..All these results suggest that LB30057 is a potent inhibitor of platelet aggregation and blood vessel relaxation induced by thrombin...
  11. doi request reprint Vascular smooth muscle dysfunction and remodeling induced by ginsenoside Rg3, a bioactive component of ginseng
    Jin Young Lee
    College of Pharmacy, Seoul National University, Seoul 151 742, Korea
    Toxicol Sci 117:505-14. 2010
    ..These results suggest that Rg3 can induce the vascular smooth muscle dysfunction by disturbing Ca(2+) influx from the L-type Ca(2+) channel, ultimately leading to impaired vascular contractility and structural remodeling...
  12. ncbi request reprint Lead-induced procoagulant activation of erythrocytes through phosphatidylserine exposure may lead to thrombotic diseases
    Jung Hun Shin
    College of Pharmacy, Seoul National University, Seoul 151 742, Korea
    Chem Res Toxicol 20:38-43. 2007
    ..These data will provide new insights into the mechanism of lead-induced cardiovascular diseases...
  13. doi request reprint Dysfunction of vascular smooth muscle and vascular remodeling by simvastatin
    Seojin Kang
    College of Pharmacy, Seoul National University, Seoul 151 742, Korea
    Toxicol Sci 138:446-556. 2014
    ..Collectively, these results demonstrate that simvastatin can impair the normal vascular contractility by disturbing Ca²⁺ influx and RhoA activity, ultimately leading to apoptosis and structural remodeling...
  14. ncbi request reprint Arsenite-enhanced procoagulant activity through phosphatidylserine exposure in platelets
    Ok Nam Bae
    College of Pharmacy, Seoul National University, Korea
    Chem Res Toxicol 20:1760-8. 2007
    ....
  15. ncbi request reprint Temperature-dependent quinone cytotoxicity in platelets involves arylation
    Young Ah Kang
    Research Institute of Pharmaceutical Sciences, College of Pharmacy, Seoul National University, Seoul, Korea
    J Toxicol Environ Health A 65:1367-78. 2002
    ..This might be due to increased arylation capacity binding to cellular proteins as temperature rises. These data suggest that MEN-induced platelet cytotoxicity involves arylation that is temperature related...
  16. doi request reprint Salsolinol, an endogenous neurotoxin, enhances platelet aggregation and thrombus formation
    Ok Nam Bae
    College of Pharmacy, Seoul National University, Shinrim dong San 56 1, Seoul 151 742, Korea
    Thromb Haemost 100:52-9. 2008
    ..These results suggest that salsolinol-enhanced platelet aggregation could be a possible contributing factor to the thrombotic events observed in Parkinson's disease and alcoholism...