Kyeong Cheon Jung

Summary

Affiliation: Hallym University
Country: Korea

Publications

  1. pmc Immunoreactivity of CD99 in stomach cancer
    Kyeong Cheon Jung
    Department of Pathology, College of Medicine, Hallym University, Chunchon, Korea
    J Korean Med Sci 17:483-9. 2002
  2. ncbi Delayed allograft rejection by the suppression of class II transactivator
    Tae Woon Kim
    Department of Pathology, Hallym University College of Medicine, Chuncheon 200 702, Korea
    Exp Mol Med 38:210-6. 2006
  3. ncbi CD99 activates T cells via a costimulatory function that promotes raft association of TCR complex and tyrosine phosphorylation of TCR zeta
    Kwon Ik Oh
    Department of Pathology, Hallym University College of Medicine, Chuncheon 200 702, Korea
    Exp Mol Med 39:176-84. 2007
  4. pmc MHC class II-restricted interaction between thymocytes plays an essential role in the production of innate CD8+ T cells
    Hye Sook Min
    Department of Pathology, Seoul National University College of Medicine, 110 799 Seoul, Korea
    J Immunol 186:5749-57. 2011
  5. pmc In situ induction of dendritic cell-based T cell tolerance in humanized mice and nonhuman primates
    Kyeong Cheon Jung
    Department of Pathology, College of Medicine, Seoul National University, Seoul 151 742, South Korea
    J Exp Med 208:2477-88. 2011
  6. doi Effects of 60 Hz 14 microT magnetic field on the apoptosis of testicular germ cell in mice
    Yoon Won Kim
    Institute of Medical Science, School of Medicine, Hallym University, Chuncheon, Korea
    Bioelectromagnetics 30:66-72. 2009
  7. pmc Generation of PLZF+ CD4+ T cells via MHC class II-dependent thymocyte-thymocyte interaction is a physiological process in humans
    You Jeong Lee
    Department of Pathology, Seoul National University College of Medicine, Seoul 110 799, Korea
    J Exp Med 207:237-46. 2010
  8. pmc Interaction between the mouse homologue of CD99 and its ligand PILR as a mechanism of T cell receptor-independent thymocyte apoptosis
    Hyo Jin Park
    Department of Pathology, Seoul National University College of Medicine, Seoul 110 799, Korea
    Exp Mol Med 42:353-65. 2010
  9. pmc CD99-dependent expansion of myeloid-derived suppressor cells and attenuation of graft-versus-host disease
    Hyo Jin Park
    Department of Pathology, Seoul National University College of Medicine, Seoul 110 799, Korea
    Mol Cells 33:259-67. 2012
  10. ncbi T cell expression of CIITA represses Th1 immunity
    Weon Seo Park
    Department of Pathology, Kangwon University College of Medicine, Chunchon, Korea
    Int Immunol 16:1355-64. 2004

Collaborators

Detail Information

Publications27

  1. pmc Immunoreactivity of CD99 in stomach cancer
    Kyeong Cheon Jung
    Department of Pathology, College of Medicine, Hallym University, Chunchon, Korea
    J Korean Med Sci 17:483-9. 2002
    ....
  2. ncbi Delayed allograft rejection by the suppression of class II transactivator
    Tae Woon Kim
    Department of Pathology, Hallym University College of Medicine, Chuncheon 200 702, Korea
    Exp Mol Med 38:210-6. 2006
    ..Both the tumor challenge and skin graft studies suggest the inhibition of CIITA molecules in donor tissue would be beneficial to the control of allo-response...
  3. ncbi CD99 activates T cells via a costimulatory function that promotes raft association of TCR complex and tyrosine phosphorylation of TCR zeta
    Kwon Ik Oh
    Department of Pathology, Hallym University College of Medicine, Chuncheon 200 702, Korea
    Exp Mol Med 39:176-84. 2007
    ..These data demonstrate the unique properties of CD99 co-stimulation that distinguish this molecule from CD28 and other raft-resident co-stimulatory factors...
  4. pmc MHC class II-restricted interaction between thymocytes plays an essential role in the production of innate CD8+ T cells
    Hye Sook Min
    Department of Pathology, Seoul National University College of Medicine, 110 799 Seoul, Korea
    J Immunol 186:5749-57. 2011
    ..It suggests that PLZF(+) T-T CD4(+) T cells in combination with Eomes(+) CD8(+) T cells might actively participate in the innate immune response against various pathogens, particularly in human perinatal period...
  5. pmc In situ induction of dendritic cell-based T cell tolerance in humanized mice and nonhuman primates
    Kyeong Cheon Jung
    Department of Pathology, College of Medicine, Seoul National University, Seoul 151 742, South Korea
    J Exp Med 208:2477-88. 2011
    ..T cell responses to unrelated antigens remained unaffected. In situ induction of DC-mediated T cell tolerance using this method may represent a potent therapeutic tool for preventing graft rejection...
  6. doi Effects of 60 Hz 14 microT magnetic field on the apoptosis of testicular germ cell in mice
    Yoon Won Kim
    Institute of Medical Science, School of Medicine, Hallym University, Chuncheon, Korea
    Bioelectromagnetics 30:66-72. 2009
    ..These results indicate that apoptosis may be induced in spermatogenic cells in mice by continuous exposure to 60 Hz MF of 14 microT...
  7. pmc Generation of PLZF+ CD4+ T cells via MHC class II-dependent thymocyte-thymocyte interaction is a physiological process in humans
    You Jeong Lee
    Department of Pathology, Seoul National University College of Medicine, Seoul 110 799, Korea
    J Exp Med 207:237-46. 2010
    ..These findings define a novel human CD4+ T cell subset that develops via an MHC class II-dependent T-T interaction...
  8. pmc Interaction between the mouse homologue of CD99 and its ligand PILR as a mechanism of T cell receptor-independent thymocyte apoptosis
    Hyo Jin Park
    Department of Pathology, Seoul National University College of Medicine, Seoul 110 799, Korea
    Exp Mol Med 42:353-65. 2010
    ..Based on these data, we propose a mechanism for thymocyte depletion in which the interaction between D4 and PILR delivers an active signal...
  9. pmc CD99-dependent expansion of myeloid-derived suppressor cells and attenuation of graft-versus-host disease
    Hyo Jin Park
    Department of Pathology, Seoul National University College of Medicine, Seoul 110 799, Korea
    Mol Cells 33:259-67. 2012
    ..Therefore, these results suggest that CD99 plays a crucial role in the attenuation of graft-versus-host disease by regulating the expansion of myeloid-derived suppressor cells...
  10. ncbi T cell expression of CIITA represses Th1 immunity
    Weon Seo Park
    Department of Pathology, Kangwon University College of Medicine, Chunchon, Korea
    Int Immunol 16:1355-64. 2004
    ....
  11. doi Targeting of a developmentally regulated epitope of CD43 for the treatment of acute leukemia
    Yoon Kyung Jeon
    Department of Pathology, Seoul National University College of Medicine, Seoul 110 799, Korea
    Cancer Immunol Immunother 60:1697-706. 2011
    ..001). These preclinical results further support the therapeutic potential of the JL1 antibody in the management of acute leukemia...
  12. pmc Overexpression of CIITA in T cells aggravates Th2-mediated colitis in mice
    Tae Woon Kim
    Department of Pathology, Hallym University College of Medicine, Chuncheon, Korea
    J Korean Med Sci 21:877-82. 2006
    ..Together, these data demonstrate that constitutive expression of CIITA in T cells skews immune response to Th2, resulting in aggravation of Th2-mediated colitis in vivo...
  13. doi Use of the JL1 epitope, which encompasses the nonglycosylation site of CD43, as a marker of immature/neoplastic Langerhans cells
    Hyo Jin Park
    Department of Pathology, Seoul National University Bundang Hospital, Seongnam, Korea
    Am J Surg Pathol 36:1150-7. 2012
    ..On the basis of these findings, we propose that the anti-JL1 antibody is a specific marker of immaturity, a feature that is shared in neoplastic LCs, and can be useful in the diagnosis of LCH...
  14. ncbi TCR-independent and caspase-independent apoptosis of murine thymocytes by CD24 cross-linking
    Kyeong Cheon Jung
    Department of Pathology, Hallym University College of Medicine, Chuncheon, Korea
    J Immunol 172:795-802. 2004
    ..In this study, we suggest that CD24 ligation induced the apoptosis of immature thymocytes independently of both caspase and TCR...
  15. pmc NKT cells play critical roles in the induction of oral tolerance by inducing regulatory T cells producing IL-10 and transforming growth factor beta, and by clonally deleting antigen-specific T cells
    Hyun Jung Kim
    Department of Pathology, Seoul National University College of Medicine, Chongno Gu, Seoul, Korea
    Immunology 118:101-11. 2006
    ..10 CD1d-/- mice. In conclusion, NKT cells were found to play an indispensable role in oral tolerance by inducing regulatory T cells, and clonally deleting antigen-specific CD4+ T cells...
  16. ncbi Characterization and epitope mapping of two monoclonal antibodies against human CD99
    Min Chan Gil
    Department of Pathology, Seoul National University College of Medicine, Seoul 110 799, Korea
    Exp Mol Med 34:411-8. 2002
    ..27 x 10(-7) and 7.08 x 10(-9) M, respectively. These studies will help understand the functional domains and the subsequent signaling mechanism of CD99...
  17. doi MHC class II-dependent T-T interactions create a diverse, functional and immunoregulatory reaction circle
    You Jeong Lee
    Department of Pathology, Seoul National University, College of Medicine, Seoul, Korea
    Immunol Cell Biol 87:65-71. 2009
    ..All of these features make it possible to create a diverse set of functional cells through MHC class II-restricted T-T interactions...
  18. ncbi Distinct expression patterns of E-cadherin and beta-catenin in signet ring cell carcinoma components of primary pulmonary adenocarcinoma
    Kyung Chul Moon
    Department of Pathology, Seoul National University College of Medicine, Seoul, Korea
    Arch Pathol Lab Med 130:1320-5. 2006
    ..Primary signet ring cell carcinoma (SRCC) of the lung is a rare variant of pulmonary adenocarcinoma, and E-cadherin and beta-catenin expressions of this tumor have not been documented, to our knowledge...
  19. pmc Distinct patterns of cleavage and translocation of cell cycle control proteins in CD95-induced and p53-induced apoptosis
    Weon Seo Park
    Department of Pathology, Kangwon National University College of Medicine, Korea
    J Korean Med Sci 18:467-72. 2003
    ..Thus, although both types of apoptosis involved caspase activation, the cell cycle related proteins responded differently. This argues against the idea that p53-induced apoptosis occurs through the induction of CD95/CD95L expression...
  20. ncbi Effects of 60 Hz electromagnetic field exposure on testicular germ cell apoptosis in mice
    Jin Sang Lee
    Department of Medical Science, Hallym University, School of Medicine, Chunchon 200 060, Korea
    Asian J Androl 6:29-34. 2004
    ..To evaluate the effects of 60 Hz extremely low frequency (ELF) elelctromagnetic field (EMF) exposure on germ cell apoptosis in the testis of mice...
  21. ncbi Therapeutic effects of lysophosphatidylcholine in experimental sepsis
    Ji Jing Yan
    Department of Pharmacology, College of Medicine, Institute of Natural Medicine, Hallym University, 1 Okchon Dong, Chunchon, Gangwon Do, 200 702, South Korea
    Nat Med 10:161-7. 2004
    ..These results suggest that LPC can effectively prevent and treat sepsis and microbial infections...
  22. pmc Correlation of immunohistochemical markers and BRAF mutation status with histological variants of papillary thyroid carcinoma in the Korean population
    Hye Sook Min
    Department of Pathology, Seoul National University College of Medicine, Seoul, Korea
    J Korean Med Sci 28:534-41. 2013
    ..043). Immunohistochemical evaluation showed characteristic patterns in histological variants. PTEN and S100A4 expression are suggested as indicators of regional lymph node metastasis...
  23. ncbi Exoenzyme Tat-C3 inhibits association of zymosan particles, phagocytosis, adhesion, and complement binding in macrophage cells
    Jinseu Park
    Department of Genetic Engineering, Division of Life Sciences, Hallym University, Chunchon 200 702, Korea
    Mol Cells 16:216-23. 2003
    ..These results suggest that Rho regulates the activity of integrins that are involved in the association of particles with macrophages, phagocytosis, adhesion, and binding of complement C3 and C3bi...
  24. ncbi Mutations of the immunoglobulin heavy chain variable region gene in CD99-deficient BJAB cell line
    Young Ho Suh
    Department of Pathology, Seoul National University College of Medicine, Korea
    Mol Cells 13:237-44. 2002
    ..We expect that the analysis of the mutation pattern of the CD99-deficient BJAB cell line might be the basis for the understanding of the molecular and cellular mechanism that regulate somatic mutation and B cell selection...
  25. ncbi The CD99 signal enhances Fas-mediated apoptosis in the human leukemic cell line, Jurkat
    Kyeong Cheon Jung
    Department of Pathology, Hallym University College of Medicine, 1 Okchon Dong, Chunchon 200 702, Kangwon Do, South Korea
    FEBS Lett 554:478-84. 2003
    ..These results suggest that each CD99 epitope plays a distinct role in T cell biology, especially in T cell apoptosis...
  26. ncbi Functional involvement of src and focal adhesion kinase in a CD99 splice variant-induced motility of human breast cancer cells
    Hyuk Joon Lee
    Vascular System Research Center, Division of Life Sciences, College of Natural Sciences, Kangwon National University, Chunchon 200 701, Korea
    Exp Mol Med 34:177-83. 2002
    ..These results suggest that src and focal adhesion kinase mediate the intracellular signaling pathway of a CD99 splice variant for the induction of motility of human breast cancer cells...
  27. ncbi Rapid divergency of rodent CD99 orthologs: implications for the evolution of the pseudoautosomal region
    Seong Hoe Park
    Department of Pathology, Seoul National University College of Medicine, 28 Yongon dong Chongno gu, Seoul 110 799, South Korea
    Gene 353:177-88. 2005
    ....