Haihong Shen

Summary

Affiliation: Gwangju Institute of Science and Technology
Country: Korea

Publications

  1. ncbi UAP56- a key player with surprisingly diverse roles in pre-mRNA splicing and nuclear export
    Haihong Shen
    Department of Life Science, Gwangju Institute of Science and Technology, Gwangju, Korea
    BMB Rep 42:185-8. 2009
  2. ncbi The U2AF35-related protein Urp contacts the 3' splice site to promote U12-type intron splicing and the second step of U2-type intron splicing
    Haihong Shen
    Department of Life Science, Gwangju Institute of Science and Technology, Gwangju 500 712, Korea
    Genes Dev 24:2389-94. 2010
  3. ncbi Chimeric RNAs as potential biomarkers for tumor diagnosis
    Jianhua Zhou
    Nantong University, Nantong, Jiangsu, P R China
    BMB Rep 45:133-40. 2012
  4. ncbi Distinct activities of the DExD/H-box splicing factor hUAP56 facilitate stepwise assembly of the spliceosome
    Haihong Shen
    Department of Life Science, Gwangju Institute of Science and Technology, Gwangju 500 712, Korea
    Genes Dev 22:1796-803. 2008
  5. ncbi Validation of trans-acting elements that promote exon 7 skipping of SMN2 in SMN2-GFP stable cell line
    Sunghee Cho
    School of Life Sciences, Gwangju Institute of Science and Technology, Gwangju 500 712, Republic of Korea
    Biochem Biophys Res Commun 423:531-5. 2012
  6. ncbi Identification of novel splicing variants from RON proto-oncogene pre-mRNA
    Heegyum Moon
    School of Life Sciences, Gwangju Institute of Science and Technology, Gwangju 500 712, Republic of Korea
    Oncol Rep 28:2217-20. 2012
  7. ncbi Identification of a novel cis-element that regulates alternative splicing of Bcl-x pre-mRNA
    Jaehoon Lee
    School of Life Science, Gwangju Institute of Science and Technology, Gwangju 500 712, Republic of Korea
    Biochem Biophys Res Commun 420:467-72. 2012

Collaborators

Detail Information

Publications7

  1. ncbi UAP56- a key player with surprisingly diverse roles in pre-mRNA splicing and nuclear export
    Haihong Shen
    Department of Life Science, Gwangju Institute of Science and Technology, Gwangju, Korea
    BMB Rep 42:185-8. 2009
    ..Collective evidence indicates that UAP56 has an essential role in mRNA nuclear export. This mini-review summarizes recent evidence for the role of UAP56 in pre-mRNA splicing and nuclear export...
  2. ncbi The U2AF35-related protein Urp contacts the 3' splice site to promote U12-type intron splicing and the second step of U2-type intron splicing
    Haihong Shen
    Department of Life Science, Gwangju Institute of Science and Technology, Gwangju 500 712, Korea
    Genes Dev 24:2389-94. 2010
    ..Thus, through recognition of a common splicing element, Urp facilitates distinct steps of U2- and U12-type intron splicing...
  3. ncbi Chimeric RNAs as potential biomarkers for tumor diagnosis
    Jianhua Zhou
    Nantong University, Nantong, Jiangsu, P R China
    BMB Rep 45:133-40. 2012
    ..BMB reports 2012; 45(3): 133-140]...
  4. ncbi Distinct activities of the DExD/H-box splicing factor hUAP56 facilitate stepwise assembly of the spliceosome
    Haihong Shen
    Department of Life Science, Gwangju Institute of Science and Technology, Gwangju 500 712, Korea
    Genes Dev 22:1796-803. 2008
    ..Our results indicate that hUAP56 first interacts with U2AF(65) in an ATP-dependent manner, and subsequently with U4/U6 snRNAs to facilitate stepwise assembly of the spliceosome...
  5. ncbi Validation of trans-acting elements that promote exon 7 skipping of SMN2 in SMN2-GFP stable cell line
    Sunghee Cho
    School of Life Sciences, Gwangju Institute of Science and Technology, Gwangju 500 712, Republic of Korea
    Biochem Biophys Res Commun 423:531-5. 2012
    ..We conclude that we have established the stable cell lines that recapitulate alternative splicing of the SMN1 and SMN2 genes. The stable cell line can be used to identify the trans-acting elements with siRNA...
  6. ncbi Identification of novel splicing variants from RON proto-oncogene pre-mRNA
    Heegyum Moon
    School of Life Sciences, Gwangju Institute of Science and Technology, Gwangju 500 712, Republic of Korea
    Oncol Rep 28:2217-20. 2012
    ..In one variant intron 6 is included, but intron 6 is skipped in another variant. These two variants should be truncated but these proteins have not yet been detected...
  7. ncbi Identification of a novel cis-element that regulates alternative splicing of Bcl-x pre-mRNA
    Jaehoon Lee
    School of Life Science, Gwangju Institute of Science and Technology, Gwangju 500 712, Republic of Korea
    Biochem Biophys Res Commun 420:467-72. 2012
    ..This element could be potentially targeted to alter the ratio of Bcl-xL and Bcl-xS for treatment of tumors through an apoptotic pathway...