Joo Young Lee

Summary

Affiliation: Gwangju Institute of Science and Technology
Country: Korea

Publications

  1. ncbi request reprint The modulation of inflammatory gene expression by lipids: mediation through Toll-like receptors
    Joo Y Lee
    Department of Life Science, Gwangju Institute of Science and Technology, Gwangju 500 712, Korea
    Mol Cells 21:174-85. 2006
  2. pmc Intrinsic and extrinsic regulation of innate immune receptors
    Eunshil Jeong
    School of Life Science, Gwangju Institute of Science and Technology, Gwangju 500 712, Korea
    Yonsei Med J 52:379-92. 2011
  3. doi request reprint Retinol suppresses the activation of Toll-like receptors in MyD88- and STAT1-independent manners
    So Young Kim
    School of Life Sciences, Gwangju Institute of Science and Technology, Gwangju, 500 712, Korea
    Inflammation 36:426-33. 2013
  4. pmc Suppression of Toll-like receptor 4 activation by caffeic acid phenethyl ester is mediated by interference of LPS binding to MD2
    So Young Kim
    School of Life Sciences, Gwangju Institute of Science and Technology, Gwangju, Korea
    Br J Pharmacol 168:1933-45. 2013
  5. doi request reprint PI3K/Akt contributes to increased expression of Toll-like receptor 4 in macrophages exposed to hypoxic stress
    So Young Kim
    School of Life Sciences, Gwangju Institute of Science and Technology, Republic of Korea
    Biochem Biophys Res Commun 419:466-71. 2012
  6. doi request reprint Akt contributes to activation of the TRIF-dependent signaling pathways of TLRs by interacting with TANK-binding kinase 1
    Sun Myung Joung
    School of Life Sciences, Gwangju Institute of Science and Technology, Gwangju, Korea
    J Immunol 186:499-507. 2011
  7. pmc Hypoxic stress up-regulates the expression of Toll-like receptor 4 in macrophages via hypoxia-inducible factor
    So Young Kim
    Cell Dynamics Research Centre, Gwangju Institute of Science and Technology, Gwangju, Korea
    Immunology 129:516-24. 2010
  8. doi request reprint Alteration of Toll-like receptor 4 activation by 4-hydroxy-2-nonenal mediated by the suppression of receptor homodimerization
    Yoon Sun Kim
    Cell Dynamics Research Center, Gwangju Institute of Science and Technology, Gwangju 500 712, Republic of Korea
    Chem Biol Interact 182:59-66. 2009
  9. ncbi request reprint Differential modulation of Nods signaling pathways by fatty acids in human colonic epithelial HCT116 cells
    Ling Zhao
    Western Human Nutrition Research Center, The Agricultural Research Service United States Department of Agriculture, Davis, California 95616, USA
    J Biol Chem 282:11618-28. 2007
  10. ncbi request reprint Saturated fatty acid activates but polyunsaturated fatty acid inhibits Toll-like receptor 2 dimerized with Toll-like receptor 6 or 1
    Joo Y Lee
    Western Human Nutrition Research Center, The Agricultural Research Service United States Department of Agriculture, and Department of Nutrition, University of California Davis, Davis, California 95616, USA
    J Biol Chem 279:16971-9. 2004

Collaborators

  • Mi Ryoung Song
  • So Young Kim
  • Eunshil Jeong
  • Sun Myung Joung
  • Zee Yong Park
  • Jung Eun Koo
  • Yoon Sun Kim
  • Ling Zhao
  • Nisha Tyagi
  • Kyung Min Lim
  • Jaeyoung Choi
  • Yun Jee Seo
  • Shilpa Rani
  • Osamu Takeuchi
  • Shizuo Akira
  • Yong Jun Choi
  • Yi Sook Jung
  • Byung Ho Lee
  • Koichi Fukase
  • Myung Ja Kwon
  • Daniel H Hwang
  • Naohiro Inohara
  • Shurong Huang

Detail Information

Publications11

  1. ncbi request reprint The modulation of inflammatory gene expression by lipids: mediation through Toll-like receptors
    Joo Y Lee
    Department of Life Science, Gwangju Institute of Science and Technology, Gwangju 500 712, Korea
    Mol Cells 21:174-85. 2006
    ....
  2. pmc Intrinsic and extrinsic regulation of innate immune receptors
    Eunshil Jeong
    School of Life Science, Gwangju Institute of Science and Technology, Gwangju 500 712, Korea
    Yonsei Med J 52:379-92. 2011
    ....
  3. doi request reprint Retinol suppresses the activation of Toll-like receptors in MyD88- and STAT1-independent manners
    So Young Kim
    School of Life Sciences, Gwangju Institute of Science and Technology, Gwangju, 500 712, Korea
    Inflammation 36:426-33. 2013
    ....
  4. pmc Suppression of Toll-like receptor 4 activation by caffeic acid phenethyl ester is mediated by interference of LPS binding to MD2
    So Young Kim
    School of Life Sciences, Gwangju Institute of Science and Technology, Gwangju, Korea
    Br J Pharmacol 168:1933-45. 2013
    ..We investigated the effect of caffeic acid phenethyl ester (CAPE) on TLR-mediated inflammation and the underlying regulatory mechanism...
  5. doi request reprint PI3K/Akt contributes to increased expression of Toll-like receptor 4 in macrophages exposed to hypoxic stress
    So Young Kim
    School of Life Sciences, Gwangju Institute of Science and Technology, Republic of Korea
    Biochem Biophys Res Commun 419:466-71. 2012
    ..These reveal a novel mechanism for regulation of TLR4 expression upon hypoxic stress and provide a therapeutic target for chronic diseases related to hypoxic stress...
  6. doi request reprint Akt contributes to activation of the TRIF-dependent signaling pathways of TLRs by interacting with TANK-binding kinase 1
    Sun Myung Joung
    School of Life Sciences, Gwangju Institute of Science and Technology, Gwangju, Korea
    J Immunol 186:499-507. 2011
    ..To our knowledge, our results demonstrate a new regulatory mechanism for Akt activation mediated by TBK1 and a novel role of Akt in TLR-mediated immune responses...
  7. pmc Hypoxic stress up-regulates the expression of Toll-like receptor 4 in macrophages via hypoxia-inducible factor
    So Young Kim
    Cell Dynamics Research Centre, Gwangju Institute of Science and Technology, Gwangju, Korea
    Immunology 129:516-24. 2010
    ....
  8. doi request reprint Alteration of Toll-like receptor 4 activation by 4-hydroxy-2-nonenal mediated by the suppression of receptor homodimerization
    Yoon Sun Kim
    Cell Dynamics Research Center, Gwangju Institute of Science and Technology, Gwangju 500 712, Republic of Korea
    Chem Biol Interact 182:59-66. 2009
    ..They further suggest that 4-HNE influences innate immune responses at sites of infection and inflammation by inhibiting TLR4 activation...
  9. ncbi request reprint Differential modulation of Nods signaling pathways by fatty acids in human colonic epithelial HCT116 cells
    Ling Zhao
    Western Human Nutrition Research Center, The Agricultural Research Service United States Department of Agriculture, Davis, California 95616, USA
    J Biol Chem 282:11618-28. 2007
    ..The results suggest that Nods may be involved in inducing sterile inflammation, one of the key etiological conditions in the development of many chronic inflammatory diseases...
  10. ncbi request reprint Saturated fatty acid activates but polyunsaturated fatty acid inhibits Toll-like receptor 2 dimerized with Toll-like receptor 6 or 1
    Joo Y Lee
    Western Human Nutrition Research Center, The Agricultural Research Service United States Department of Agriculture, and Department of Nutrition, University of California Davis, Davis, California 95616, USA
    J Biol Chem 279:16971-9. 2004
    ..These results also suggest that inflammatory responses induced by the activation of TLRs can be differentially modulated by types of dietary fatty acids...
  11. ncbi request reprint Reciprocal modulation of Toll-like receptor-4 signaling pathways involving MyD88 and phosphatidylinositol 3-kinase/AKT by saturated and polyunsaturated fatty acids
    Joo Y Lee
    Western Human Nutrition Research Center, Agricultural Research Service, United States Department of Agriculture, Davis, California 95616, USA
    J Biol Chem 278:37041-51. 2003
    ....