Regis Grailhe

Summary

Country: Korea

Publications

  1. ncbi request reprint Monitoring protein interactions in the living cell through the fluorescence decays of the cyan fluorescent protein
    Regis Grailhe
    Institut Pasteur, Laboratoire Recepteurs et Cognition, 25 rue du Dr Roux, F 75015 Paris, France
    Chemphyschem 7:1442-54. 2006
  2. ncbi request reprint Long-term exposure to nicotine modulates the level and activity of acetylcholine receptors in white blood cells of smokers and model mice
    Anne Cormier
    Recepteurs et Cognition, Unité de REecherche Associée D1284, Centre National de la Recherche Scientifique, Institut Pasteur, Paris, France
    Mol Pharmacol 66:1712-8. 2004
  3. pmc Pore conformations and gating mechanism of a Cys-loop receptor
    Yoav Paas
    Recepteurs et Cognition, Unité de Recherche Associée 2182 Centre National de la Recherche Scientifique, Institut Pasteur, 25 rue du Docteur Roux, 75724 Paris Cedex 15, France
    Proc Natl Acad Sci U S A 102:15877-82. 2005
  4. ncbi request reprint Distinct subcellular targeting of fluorescent nicotinic alpha 3 beta 4 and serotoninergic 5-HT3A receptors in hippocampal neurons
    Regis Grailhe
    Recepteurs et Cognition, Unité de recherche associée D1284, CNRS, Institut Pasteur, 25 rue du Dr Roux, 75724 Paris, France
    Eur J Neurosci 19:855-62. 2004
  5. ncbi request reprint Beta2-containing nicotinic receptors contribute to the organization of sleep and regulate putative micro-arousals in mice
    Clément Léna
    Recepteurs et Cognition, Unité de Recherche Associée Centre National de la Recherche Scientifique, Institut Pasteur, 757242 Paris Cedex 15, France
    J Neurosci 24:5711-8. 2004
  6. pmc Electron microscopic evidence for nucleation and growth of 3D acetylcholine receptor microcrystals in structured lipid-detergent matrices
    Yoav Paas
    Recepteurs et Cognition, Unité de Recherche Associée 2182, Centre National de la Recherche Scientifique, Institut Pasteur, 25 rue du Docteur Roux, 75724 Paris Cedex 15, France
    Proc Natl Acad Sci U S A 100:11309-14. 2003

Collaborators

Detail Information

Publications6

  1. ncbi request reprint Monitoring protein interactions in the living cell through the fluorescence decays of the cyan fluorescent protein
    Regis Grailhe
    Institut Pasteur, Laboratoire Recepteurs et Cognition, 25 rue du Dr Roux, F 75015 Paris, France
    Chemphyschem 7:1442-54. 2006
    ..These phenomena require careful consideration in intracellular FRET studies...
  2. ncbi request reprint Long-term exposure to nicotine modulates the level and activity of acetylcholine receptors in white blood cells of smokers and model mice
    Anne Cormier
    Recepteurs et Cognition, Unité de REecherche Associée D1284, Centre National de la Recherche Scientifique, Institut Pasteur, Paris, France
    Mol Pharmacol 66:1712-8. 2004
    ..The phenomenon of nAChR up-regulation in WBCs provides a simple tool to evaluate and study tobacco addiction...
  3. pmc Pore conformations and gating mechanism of a Cys-loop receptor
    Yoav Paas
    Recepteurs et Cognition, Unité de Recherche Associée 2182 Centre National de la Recherche Scientifique, Institut Pasteur, 25 rue du Docteur Roux, 75724 Paris Cedex 15, France
    Proc Natl Acad Sci U S A 102:15877-82. 2005
    ..Alignment of the functional results with the 3D structure of an acetylcholine receptor allowed us to generate structural models accounting for the closed and open pore conformations and for a gating mechanism of a Cys-loop receptor...
  4. ncbi request reprint Distinct subcellular targeting of fluorescent nicotinic alpha 3 beta 4 and serotoninergic 5-HT3A receptors in hippocampal neurons
    Regis Grailhe
    Recepteurs et Cognition, Unité de recherche associée D1284, CNRS, Institut Pasteur, 25 rue du Dr Roux, 75724 Paris, France
    Eur J Neurosci 19:855-62. 2004
    ..Taken together, the fluorescent and electrophysiological studies presented here demonstrate the predominant intracellular location of alpha3beta4-nACh receptors and the predominant expression of the 5-HT3AR in dendritic surface loci...
  5. ncbi request reprint Beta2-containing nicotinic receptors contribute to the organization of sleep and regulate putative micro-arousals in mice
    Clément Léna
    Recepteurs et Cognition, Unité de Recherche Associée Centre National de la Recherche Scientifique, Institut Pasteur, 757242 Paris Cedex 15, France
    J Neurosci 24:5711-8. 2004
    ..Our results show that the beta2-containing nAChRs contribute to the organization of sleep by regulating the transient phasic activity in NREMS, the REMS onset and duration, and the REMS-promoting effect of stress...
  6. pmc Electron microscopic evidence for nucleation and growth of 3D acetylcholine receptor microcrystals in structured lipid-detergent matrices
    Yoav Paas
    Recepteurs et Cognition, Unité de Recherche Associée 2182, Centre National de la Recherche Scientifique, Institut Pasteur, 25 rue du Docteur Roux, 75724 Paris Cedex 15, France
    Proc Natl Acad Sci U S A 100:11309-14. 2003
    ..The latter are stable in detergent-containing aqueous solutions and can currently be used for seeding and epitaxial growth, en route to crystals of appropriate dimensions for x-ray diffraction studies...