Ji Young Park

Summary

Affiliation: Gachon Medical School
Country: Korea

Publications

  1. ncbi Effect of rifampin on the pharmacokinetics of rosiglitazone in healthy subjects
    Ji Young Park
    Departmernts of Pharmacology and Endocrinology, Gil Medical Center, Gachon Medical School, 1198 Kuwol dong, Namdong gu, Incheon 405 760, South Korea
    Clin Pharmacol Ther 75:157-62. 2004
  2. ncbi Quantification of gliclazide by semi-micro high-performance liquid chromatography: application to a bioequivalence study of two formulations in healthy subjects
    Ji Young Park
    Department of Pharmacology, Gil Medical Center, Gachon Medical School, 1198 Kuwol dong, Namdong gu, Incheon 405 760, Republic of Korea
    J Pharm Biomed Anal 35:943-9. 2004
  3. pmc Chloramphenicol is a potent inhibitor of cytochrome P450 isoforms CYP2C19 and CYP3A4 in human liver microsomes
    Ji Young Park
    Department of Pharmacology, Gachon Medical School, Incheon, Korea
    Antimicrob Agents Chemother 47:3464-9. 2003
  4. ncbi Randomized, open-label, two-period crossover comparison of the pharmacokinetic and pharmacodynamic properties of two amlodipine formulations in healthy adult male Korean subjects
    Ji Young Park
    Department of Pharmacology, Clinical Trial Center, Gil Medical Center, Gachon Medical School, 1198 Kuwol dong, Namdong gu, Incheon 405 760, Korea
    Clin Ther 26:715-23. 2004
  5. pmc Effect of ketoconazole on the pharmacokinetics of rosiglitazone in healthy subjects
    Ji Young Park
    Department of Pharmacology, Gachon Medical School and Clinical Trial Centre, Gil Medical Centre, Incheon, Korea
    Br J Clin Pharmacol 58:397-402. 2004
  6. ncbi Relative bioavailability and pharmacokinetics of a new sibutramine formulation in healthy male subjects: a randomized, open-label, two-period, comparative crossover study
    Ji Young Park
    Department of Pharmacology, Gachon Medical School, Gil Medical Center, 1198 Kuwol dong, Namdong gu, Incheon 405 760, Korea
    Clin Ther 26:2092-101. 2004
  7. ncbi Inhibitory effect of 5-fluorouracil on human cytochrome P(450) isoforms in human liver microsomes
    Ji Young Park
    Department of Pharmacology, Gachon Medical School, 1198 Kuwol dong, Namdong gu, 405 760 Incheon, Korea
    Eur J Clin Pharmacol 59:407-9. 2003
  8. ncbi Effects of CYP2C19 and CYP2C9 genetic polymorphisms on the disposition of and blood glucose lowering response to tolbutamide in humans
    Ji Hong Shon
    Department of Pharmacology, Inje University College of Medicine and Clinical Pharmacology Center, Pusan Paik Hospital, Pusan, South Korea
    Pharmacogenetics 12:111-9. 2002
  9. ncbi Enantioselective disposition of lansoprazole in extensive and poor metabolizers of CYP2C19
    Kyoung Ah Kim
    Department of Pharmacology, Inje University College of Medicine and Clinical Pharmacology Center, Pusan Paik Hospital, and the Department of Chemistry, Pusan National University, Pusan, South Korea
    Clin Pharmacol Ther 72:90-9. 2002
  10. ncbi Effect of probenecid on the pharmacokinetics of carbamazepine in healthy subjects
    Kyoung Ah Kim
    Department of Pharmacology and Gil Medical Center, Gachon Medical School and Clinical Trial Center, 1198 Kuwol dong, Namdong gu, Incheon, 405 760, Korea
    Eur J Clin Pharmacol 61:275-80. 2005

Collaborators

  • Jae Gook Shin
  • D A Flockhart
  • Jin Hyoung Kang
  • Yeul Hong Kim
  • Young Joo Min
  • Kyung Hee Lee
  • Myung Ho Hyun
  • Kyoung Ah Kim
  • Pil Whan Park
  • Ji Hong Shon
  • Eun Kyung Cho
  • In Cheol Hwang
  • Kwang Soo Kim
  • Young Ran Yoon
  • Heather D Coleman
  • Jung Seok Choi
  • Tae Hoon Lee
  • Ock Je Lee
  • Ji Young Lee
  • Kwang Hyeon Liu
  • Jong Myung Ha
  • Sun Min Jung
  • Jae youl Joung
  • Kyung Hyun Cho
  • Min Jung Kim
  • Hong Suk Song
  • Heuy Sun Suh
  • Kyoung Kon Kim
  • In June Cha
  • Hong Yup Ahn
  • Ki Dong Ko
  • Sang Myun Park
  • Ilo Jou
  • Clint Chapple
  • Jong Min Lee
  • Il Kwun Chung
  • Heon Jeong Lee
  • Ramesh Nair
  • Suck Ho Lee
  • Kwon Bok Kim
  • Do Hyun Park
  • Sang Heum Park
  • Sun Joo Kim
  • Hong Soo Kim
  • Chi Hoon Choi
  • Do Hyung Kang
  • Shawn D Mansfield
  • Wi Hoon Jung
  • Jun Soo Kwon
  • Myung Hun Jung
  • Myong Wuk Chon
  • Dong Kyun Kang
  • Kyong Rae Kim
  • Hye Jin Heo
  • Ki Whan Hong
  • Mi Ran Yun
  • Chi Dae Kim
  • Kyung Ho Shin
  • Bon Hong Min
  • Sang Hyun Choi
  • Sun Sik Bae
  • Won Suk Lee
  • Geun Young Jung
  • Boe Gwun Chun
  • Sae Ock Oh
  • Won Tan Byun
  • Hyung Kee Kim
  • Hyun Kee Cho
  • Sook Young Lee
  • Il Geun Jung
  • Jaegul Chung
  • Dong Hae Jung
  • Sabina Lim
  • Jin Ho Chun
  • Bong sik Yoon
  • Hyouk Joung
  • Jae Heung Jeon
  • Sang Seop Lee
  • Tae Sook Jeong
  • Ji Suk Lee
  • Jang Il Han
  • G Mangai Kasthuri
  • Won jin Kang
  • Hyun Soon Kim
  • Doo Hee Yun
  • Young Chae Lim
  • Moon Kyung Kim

Detail Information

Publications39

  1. ncbi Effect of rifampin on the pharmacokinetics of rosiglitazone in healthy subjects
    Ji Young Park
    Departmernts of Pharmacology and Endocrinology, Gil Medical Center, Gachon Medical School, 1198 Kuwol dong, Namdong gu, Incheon 405 760, South Korea
    Clin Pharmacol Ther 75:157-62. 2004
    ..Our objective was to investigate the effect of rifampin on the pharmacokinetics of rosiglitazone in humans...
  2. ncbi Quantification of gliclazide by semi-micro high-performance liquid chromatography: application to a bioequivalence study of two formulations in healthy subjects
    Ji Young Park
    Department of Pharmacology, Gil Medical Center, Gachon Medical School, 1198 Kuwol dong, Namdong gu, Incheon 405 760, Republic of Korea
    J Pharm Biomed Anal 35:943-9. 2004
    ..80-1.25. This result suggests that two formulations are bioequivalent when administered orally at a dose of 80 mg gliclazide...
  3. pmc Chloramphenicol is a potent inhibitor of cytochrome P450 isoforms CYP2C19 and CYP3A4 in human liver microsomes
    Ji Young Park
    Department of Pharmacology, Gachon Medical School, Incheon, Korea
    Antimicrob Agents Chemother 47:3464-9. 2003
    ..In conclusion, inhibition of CYP2C19 and CYP3A4 is the probable mechanism by which chloramphenicol decreases the clearance of coadministered drugs, which manifests as a drug interaction with chloramphenicol...
  4. ncbi Randomized, open-label, two-period crossover comparison of the pharmacokinetic and pharmacodynamic properties of two amlodipine formulations in healthy adult male Korean subjects
    Ji Young Park
    Department of Pharmacology, Clinical Trial Center, Gil Medical Center, Gachon Medical School, 1198 Kuwol dong, Namdong gu, Incheon 405 760, Korea
    Clin Ther 26:715-23. 2004
    ....
  5. pmc Effect of ketoconazole on the pharmacokinetics of rosiglitazone in healthy subjects
    Ji Young Park
    Department of Pharmacology, Gachon Medical School and Clinical Trial Centre, Gil Medical Centre, Incheon, Korea
    Br J Clin Pharmacol 58:397-402. 2004
    ..Rosiglitazone is a novel thiazolidinedione antidiabetic drug, mainly metabolized by CYP2C8 and to a lesser extent CYP2C9. We investigated the possible effect of ketoconazole on the pharmacokinetics of rosiglitazone in humans...
  6. ncbi Relative bioavailability and pharmacokinetics of a new sibutramine formulation in healthy male subjects: a randomized, open-label, two-period, comparative crossover study
    Ji Young Park
    Department of Pharmacology, Gachon Medical School, Gil Medical Center, 1198 Kuwol dong, Namdong gu, Incheon 405 760, Korea
    Clin Ther 26:2092-101. 2004
    ..Drugs formed from different salts may differ in their solubility profiles and dissolution rates, which may affect their rate of absorption and thus their onset, duration, and intensity of effect...
  7. ncbi Inhibitory effect of 5-fluorouracil on human cytochrome P(450) isoforms in human liver microsomes
    Ji Young Park
    Department of Pharmacology, Gachon Medical School, 1198 Kuwol dong, Namdong gu, 405 760 Incheon, Korea
    Eur J Clin Pharmacol 59:407-9. 2003
    ..The aim of the present study was to elucidate the inhibitory effect of 5-FU on CYP isoforms using human liver microsomes...
  8. ncbi Effects of CYP2C19 and CYP2C9 genetic polymorphisms on the disposition of and blood glucose lowering response to tolbutamide in humans
    Ji Hong Shon
    Department of Pharmacology, Inje University College of Medicine and Clinical Pharmacology Center, Pusan Paik Hospital, Pusan, South Korea
    Pharmacogenetics 12:111-9. 2002
    ..The in-vivo contribution of CYP2C19 to tolbutamide 4-methylhydroxylation appears to be minor in humans. This suggests that, at least in vivo, tolbutamide remains a selective probe for measuring CYP2C9 activity in humans...
  9. ncbi Enantioselective disposition of lansoprazole in extensive and poor metabolizers of CYP2C19
    Kyoung Ah Kim
    Department of Pharmacology, Inje University College of Medicine and Clinical Pharmacology Center, Pusan Paik Hospital, and the Department of Chemistry, Pusan National University, Pusan, South Korea
    Clin Pharmacol Ther 72:90-9. 2002
    ..To evaluate the enantioselective disposition of lansoprazole in relation to the genetic polymorphism of CYP2C19...
  10. ncbi Effect of probenecid on the pharmacokinetics of carbamazepine in healthy subjects
    Kyoung Ah Kim
    Department of Pharmacology and Gil Medical Center, Gachon Medical School and Clinical Trial Center, 1198 Kuwol dong, Namdong gu, Incheon, 405 760, Korea
    Eur J Clin Pharmacol 61:275-80. 2005
    ..There has been no clear demonstration to reveal the role of glucuronidation in the disposition of CBZ. We evaluated the effect of probenecid, a UDP-glucuronosyltransferase inhibitor, on the pharmacokinetics of CBZ in humans...
  11. ncbi Effect of rifampin on the pharmacokinetics and pharmacodynamics of gliclazide
    Ji Young Park
    Department of Pharmacology, Ghil Medical Center, Gachon Medical School, Incheon, South Korea
    Clin Pharmacol Ther 74:334-40. 2003
    ..Our objective was to investigate the effect of rifampin (INN, rifampicin) on the pharmacokinetics and pharmacodynamics of gliclazide, a sulfonylurea antidiabetic drug...
  12. ncbi Effect of quercetin on the pharmacokinetics of rosiglitazone, a CYP2C8 substrate, in healthy subjects
    Kyoung Ah Kim
    Department of Pharmacology, Gil Medical Center, Gachon Medical School, 1198 Kuwoldong, Namdong gu, Incheon 405 760, Korea
    J Clin Pharmacol 45:941-6. 2005
    ....
  13. ncbi Cytochrome P450 3A inhibitor itraconazole affects plasma concentrations of risperidone and 9-hydroxyrisperidone in schizophrenic patients
    Sun Min Jung
    Departments of Pharmacology and Laboratory Medicine, Gil Medical Center, Gachon Medical School, 1198 Kuwol dong, Namdong gu, Incheon 405 760, Korea
    Clin Pharmacol Ther 78:520-8. 2005
    ..The aim of this study was to evaluate the effect of itraconazole, a CYP3A inhibitor, on the plasma concentrations of risperidone and 9-hydroxyrisperidone in schizophrenic patients in relation to CYP2D6 genotype...
  14. ncbi Effect of CYP3A5*3 genotype on the pharmacokinetics and pharmacodynamics of alprazolam in healthy subjects
    Ji Young Park
    Department of Pharmacology, Korea University College of Medicine, Seoul, South Korea
    Clin Pharmacol Ther 79:590-9. 2006
    ..Our objective was to evaluate the effect of the CYP3A5 genotype on the pharmacokinetics and pharmacodynamics of alprazolam in healthy volunteers...
  15. ncbi Inhibitory effects of tricyclic antidepressants (TCAs) on human cytochrome P450 enzymes in vitro: mechanism of drug interaction between TCAs and phenytoin
    Jae Gook Shin
    Department of Pharmacology, Inje University College of Medicine and Clinical Pharmacology Center, Busan Paik Hospital, Busan, Seoul, Korea
    Drug Metab Dispos 30:1102-7. 2002
    ..These results suggest that TCAs inhibit both CYP2D6 and CYP2C19 and that the interaction between TCAs and phenytoin involves inhibition of CYP2C19-catalyzed phenytoin p-hydroxylation...
  16. ncbi Effect of high-dose aspirin on CYP2E1 activity in healthy subjects measured using chlorzoxazone as a probe
    Ji Young Park
    Department of Pharmacology, Gachon Medical School, 1198 Kuwol dong, Namdong gu, Incheon 405 760, Korea
    J Clin Pharmacol 46:109-14. 2006
    ..24). The AUC ratio and plasma concentration ratios of 6-hydroxychlorzoxazone/chlorzoxazone were not changed significantly by high-dose aspirin. High-dose aspirin at a therapeutic dose does not affect CYP2E1 activity in humans...
  17. ncbi Genetic polymorphisms and linkage disequilibrium of sulfotransferase SULT1A1 and SULT1A2 in a Korean population: comparison of other ethnic groups
    Kyoung Ah Kim
    Department of Pharmacology, Gil Medical Center, Gachon Medical School, 1198 Kuwol dong, Namdong gu, Incheon, 405 760, Korea
    Eur J Clin Pharmacol 61:743-7. 2005
    ..To determine the allele frequencies of sulfotransferases (SULTs) 1A1 and 1A2 and their linkage disequilibrium in a Korean population and compare them with those of other ethnic groups...
  18. ncbi Identification of cytochrome P450 isoforms involved in the metabolism of loperamide in human liver microsomes
    Kyoung Ah Kim
    Department of Pharmacology, Gil Medical Center, Gachon Medical School, 1198 Kuwol dong, 405 760, Incheon, Namdong gu, Korea
    Eur J Clin Pharmacol 60:575-81. 2004
    ..The purpose of the present study was to elucidate the cytochrome P450 (P450) isoform(s) involved in the metabolism of loperamide (LOP) to N-demethylated LOP (DLOP) in human liver microsomes...
  19. ncbi Simple and extractionless high-performance liquid chromatographic determination of rosiglitazone in human plasma and application to pharmacokinetics in humans
    Kyoung Ah Kim
    Department of Pharmacology, Gachon Medical School, Incheon 405 760, Korea
    Biomed Chromatogr 18:613-5. 2004
    ..This method is simple, specific, sensitive and requires only a small plasma volume with short analytical time, and is suitable for the determination of plasma rosiglitazone in routine measurements for pharmacokinetic studies...
  20. pmc Effect of ABCB1 (MDR1) haplotypes derived from G2677T/C3435T on the pharmacokinetics of amlodipine in healthy subjects
    Kyoung Ah Kim
    Department of Pharmacology, Korea University College of Medicine, Seoul, Korea
    Br J Clin Pharmacol 63:53-8. 2007
    ..We aimed to investigate the effect of the ABCB1 gene on the pharmacokinetics of amlodipine...
  21. doi Open-label, randomized, single-dose, crossover study to evaluate the pharmacokinetics and safety differences between two docetaxel products, CKD-810 and Taxotere injection, in patients with advanced solid cancer
    Eun Kyung Cho
    Division of Hematology and Oncology, Department of Internal Medicine, Gachon University Gil Medical Center, Incheon, South Korea
    Cancer Chemother Pharmacol 73:9-16. 2014
    ..The aim of this study was to compare CKD-810 (test docetaxel) with Taxotere(®) (reference docetaxel) in terms of pharmacokinetics and safety for patients with advanced or metastatic carcinoma...
  22. doi Effects of CYP3A5, CYP2C19, and CYP2B6 on the clinical efficacy and adverse outcomes of sibutramine therapy: a crucial role for the CYP2B6*6 allele
    In Cheol Hwang
    Department of Family Medicine, Gachon University Gil Medical Center, Incheon, South Korea
    Clin Chim Acta 428:77-81. 2014
    ..However, there are no available data to demonstrate the association of these polymorphisms with the clinical outcomes of sibutramine administration...
  23. ncbi Functional implication of BAFF synthesis and release in gangliosides-stimulated microglia
    Kwang Soo Kim
    Department of Pharmacology, Ajou University School of Medicine, Suwon, Korea
    J Leukoc Biol 86:349-59. 2009
    ..These findings imply that BAFF secreted by microglia may play important roles in CNS inflammation by regulating microglia as well as infiltrated B cells...
  24. doi Gomisin A induces Ca2+-dependent activation of eNOS in human coronary artery endothelial cells
    Ji Young Park
    Department of Pharmacology, School of Medicine, and MRC for Ischemic Tissue Regeneration and Medical Research Institute, Pusan National University, Yangsan, Gyeongnam 626 770, Republic of Korea
    J Ethnopharmacol 125:291-6. 2009
    ..In this study, we examined whether GA could actually induce nitric oxide (NO) production and clarified the mechanism in cultured human coronary artery endothelial cells (HCAEC)...
  25. ncbi 4-Hydroxynonenal induces vascular smooth muscle cell apoptosis through mitochondrial generation of reactive oxygen species
    Ji Young Lee
    Department of Pharmacology, College of Medicine, Pusan National University, 10 Ami dong 1 ga, Seo Gu, Busan, Republic of Korea
    Toxicol Lett 166:212-21. 2006
    ..Taken together, these results suggest that mitochondrial dysfunction plays a key role in mediating HNE-induced VSMC apoptosis through an increased mitochondrial production of ROS...
  26. ncbi Pharmacokinetic and pharmacodynamic characteristics of a new S-amlodipine formulation in healthy Korean male subjects: a randomized, open-label, two-period, comparative, crossover study
    Ji Young Park
    Department of Clinical Pharmacology and Toxicology, Anam Hospital, Korea University College of Medicine, Seoul, Korea
    Clin Ther 28:1837-47. 2006
    ..It is used therapeutically as a racemic mixture, composed of S- and R-enantiomers, but its calcium channel-blocking effect is confined to S-amlodipine; R-amlodipine has 1000-fold less activity than its S-enantiomer...
  27. ncbi Effect of rifampin, an inducer of CYP3A and P-glycoprotein, on the pharmacokinetics of risperidone
    Kyoung Ah Kim
    Department of Clinical Pharmacology and Toxicology, Anam Hospital, Korea University College of Medicine, 126 1, Anam Dong 5 Ga, Sungbuk Gu, Seoul 136 705, Korea
    J Clin Pharmacol 48:66-72. 2008
    ..Thus, rifampin reduced the exposure to risperidone, probably because of a decrease in its bioavailability through the induction of CYP3A and probably P-glycoprotein...
  28. ncbi Effect of polymorphic CYP3A5 genotype on the single-dose simvastatin pharmacokinetics in healthy subjects
    Kyoung Ah Kim
    Department of Clinical Pharmacology and Toxicology, Anam Hospital, Korea University College of Medicine, 126 1, Anam Dong 5 Ga, Sungbuk Gu, Seoul 136 705, Korea
    J Clin Pharmacol 47:87-93. 2007
    ..These findings suggest that the polymorphic CYP3A5 gene affects the disposition of simvastatin and provides a plausible explanation for interindividual variability of simvastatin disposition...
  29. ncbi Effect of CYP3A5*3 genotype on the pharmacokinetics and pharmacodynamics of amlodipine in healthy Korean subjects
    Kyoung Ah Kim
    Department of Clinical Pharmacology, Anam Hospital, Korea University College of Medicine, Sungbuk Gu, Seoul, South Korea
    Clin Pharmacol Ther 80:646-56. 2006
    ..We investigated the effect of CYP3A5*3 genotype on the pharmacokinetics and pharmacodynamics of amlodipine in healthy Korean male subjects...
  30. pmc Effect of multiple doses of montelukast on the pharmacokinetics of rosiglitazone, a CYP2C8 substrate, in humans
    Kyoung Ah Kim
    Department of Clinical Pharmacology and Toxicology, Anam Hospital, Korea University College of Medicine, Seoul, Korea
    Br J Clin Pharmacol 63:339-45. 2007
    ..To investigate the effect of multiple dosing with montelukast, a selective leukotriene-receptor antagonist, on the pharmacokinetics of rosiglitazone, a CYP2C8 substrate, in humans...
  31. ncbi Cytochrome P450 2C8 and CYP3A4/5 are involved in chloroquine metabolism in human liver microsomes
    Kyoung Ah Kim
    Research Group of Pain and Neuroscience, East West Medical Research Institute, Kyung Hee University, Seoul, Korea
    Arch Pharm Res 26:631-7. 2003
    ..900). In conclusion, the results of the present study demonstrated that CYP2C8 and CYP3A4/5 are the major enzymes responsible for the chloroquine N-deethylation to DCQ in human liver microsomes...
  32. ncbi Combined effects of itraconazole and CYP2D6*10 genetic polymorphism on the pharmacokinetics and pharmacodynamics of haloperidol in healthy subjects
    Ji Young Park
    Department of Pharmacology and Pharmacogenetics Research Center, Inje University College of Medicine, Busan, Korea
    J Clin Psychopharmacol 26:135-42. 2006
    ..The moderate effect of CYP2D6*10 genotype on the pharmacokinetics and pharmacodynamics of haloperidol seems to be augmented by the presence of itraconazole pretreatment...
  33. ncbi Inhibitory effect of glyburide on human cytochrome p450 isoforms in human liver microsomes
    Kyoung Ah Kim
    East West Medical Research Institute, Kyunghee University, Seoul, Korea
    Drug Metab Dispos 31:1090-2. 2003
    ..It is anticipated that clinically significant drug-drug interactions will ensue when glyburide is coadministered with agents that are cleared primarily by the CYP2C9-mediated pathway and those with narrow therapeutic ranges...
  34. ncbi Cavum septum pellucidum in subjects at ultra-high risk for psychosis: compared with first-degree relatives of patients with schizophrenia and healthy volunteers
    Jung Seok Choi
    Department of Psychiatry, Seoul National University College of Medicine and Clinical Cognitive Neuroscience Center, SNU MRC, Seoul, Republic of Korea
    Prog Neuropsychopharmacol Biol Psychiatry 32:1326-30. 2008
    ..We examined whether CSP was present more frequently in subjects at ultra-high risk (UHR) for psychosis compared to first-degree relatives of patients with schizophrenia (genetic high risk, GHR) and healthy controls (HC)...
  35. pmc Aortoduodenal fistula and aortic aneurysm secondary to biliary stent-induced retroperitoneal perforation
    Tae Hoon Lee
    Department of Internal Medicine, University of Ulsan College of Medicine, Asan Medical Center, Songpagu, Seoul 138 736, South Korea
    World J Gastroenterol 14:3095-7. 2008
    ..To our knowledge, this is the first report describing a lethal complication of a bleeding, aortoduodenal fistula and caused by biliary metallic stent-induced perforation...
  36. pmc RNAi-mediated suppression of p-coumaroyl-CoA 3'-hydroxylase in hybrid poplar impacts lignin deposition and soluble secondary metabolism
    Heather D Coleman
    Department of Wood Science, University of British Columbia, 4030 2424 Main Mall, Vancouver, BC, Canada V6T 1Z4
    Proc Natl Acad Sci U S A 105:4501-6. 2008
    ..The data presented indicate that when down-regulated, C3'H becomes a rate-limiting step in lignin biosynthesis and further support the involvement of hydroxycinnamic acid shikimate esters in the lignin biosynthetic pathway...
  37. ncbi An overexpression of chalcone reductase of Pueraria montana var. lobata alters biosynthesis of anthocyanin and 5'-deoxyflavonoids in transgenic tobacco
    Jae youl Joung
    Plant Cell Biotechnology Laboratory, Korea Research Institute of Bioscience and Biotechnology, Daejon 305 333, Republic of Korea
    Biochem Biophys Res Commun 303:326-31. 2003
    ..The introduction of pl-chr gene provides a method to redirect the flavonoid pathway into 5'-deoxyflavonoid production in non-legume crops, in order to manipulate the phenylpropanoid pathway for isoflavonoid production...
  38. ncbi Stereoselective metabolism of lansoprazole by human liver cytochrome P450 enzymes
    Kyoung Ah Kim
    Department of Pharmacology and PharmacoGenomics Research Center, Inje University College of Medicine Clinical Pharmacology Center, Busan Paik Hospital Busan, Korea
    Drug Metab Dispos 31:1227-34. 2003
    ....
  39. ncbi Ligand-binding domain of farnesoid X receptor (FXR) had the highest sensitivity and activity among FXR variants in a fluorescence-based assay
    Kyung Hyun Cho
    Lipid Metabolism and Atherosclerosis Research Unit, Korea Research Institute of Bioscience and Biotechnology, Yuseong, Daejeon, South Korea, 305 333
    Lipids 38:1149-56. 2003
    ....