Eun Mi Park
Affiliation: Ewha Womans University
Shin J, Kim Y, Kim H, Kim H, Lee K, Kang J, et al
. Iron released from reactive microglia by noggin improves myelin repair in the ischemic brain. Neuropharmacology. 2018;133:202-215 pubmed publisher
..We suggest that the BMP/hepcidin pathway can be a target for the regulation of the iron status in microglia to enhance remyelination in the ischemic brain. ..
Park E, Cho S. Enhanced ERK dependent CREB activation reduces apoptosis in staurosporine-treated human neuroblastoma SK-N-BE(2)C cells. Neurosci Lett. 2006;402:190-4 pubmed
..The study indicates that enhancing endogenous survival pathways by NAMDA combined with other neuroprotective measure(s) might be a useful strategy to reduce apoptosis. ..
Shin J, Oh S, Ahn J, Park E. Estrogen receptor-mediated resveratrol actions on blood-brain barrier of ovariectomized mice. Neurobiol Aging. 2015;36:993-1006 pubmed publisher
Lee E, Ko H, Jeong Y, Park E, Kim H. Î²-Lapachone suppresses neuroinflammation by modulating the expression of cytokines and matrix metalloproteinases in activated microglia. J Neuroinflammation. 2015;12:133 pubmed publisher
..The strong anti-inflammatory/anti-oxidant effects of Î²-LAP may provide preventive therapeutic potential for various neuroinflammatory disorders. ..
Shin J, Jeong S, Kim M, Yoon J, Kim H, Park E. Visceral adipose tissue inflammation is associated with age-related brain changes and ischemic brain damage in aged mice. Brain Behav Immun. 2015;50:221-231 pubmed publisher
..We suggest that visceral adiposity should be considered as a factor affecting brain health and ischemic brain damage in the aged population. ..
Shin J, Jeong S, Kim H, Jang G, Ryu D, Ahn Y, et al
. Repression of adenosine triphosphate-binding cassette transporter ABCG2 by estrogen increases intracellular glutathione in brain endothelial cells following ischemic reperfusion injury. Neurobiol Aging. 2018;66:138-148 pubmed publisher
Shin J, Yoon J, Kim M, Park E. Activation of classical estrogen receptor subtypes reduces tight junction disruption of brain endothelial cells under ischemia/reperfusion injury. Free Radic Biol Med. 2016;92:78-89 pubmed publisher
Jeong S, Shin J, Cho S, Kim H, Lee J, Kang J, et al
. Resveratrol attenuates peripheral and brain inflammation and reduces ischemic brain injury in aged female mice. Neurobiol Aging. 2016;44:74-84 pubmed publisher
..Therefore, resveratrol administration can be a valuable strategy for the prevention of age-associated and disease-provoked inflammation in postmenopausal women. ..