- The plasma membrane redox enzyme NQO1 sustains cellular energetics and protects human neuroblastoma cells against metabolic and proteotoxic stressDong Hoon Hyun
Division of Life and Pharmaceutical Sciences, Department of Life Science, Ewha Womans University, Seoul, South Korea
Age (Dordr) 34:359-70. 2012..These findings have implications for the development of therapeutic interventions for neural tumors and neurodegenerative conditions...
- Effect of the overexpression of mutant ubiquitin (K48R) on the cellular response induced by 4-hydroxy-2,3-trans-nonenal, an end-product of lipid peroxidationDong Hoon Hyun
Department of Life Science, Division of Life and Pharmaceutical Sciences, Ewha Womans University, Seoul, South Korea
Neurosci Lett 477:115-20. 2010..These data suggest that impairment of the UPS at different levels may be a common mechanism in neurodegeneration and that more such defects remain to be identified...
- The plasma membrane redox system is impaired by amyloid β-peptide and in the hippocampus and cerebral cortex of 3xTgAD miceDong Hoon Hyun
Department of Life Science, Division of Life and Pharmaceutical Sciences, Ewha Womans University, Seoul 120 750, South Korea
Exp Neurol 225:423-9. 2010....