Aree Moon

Summary

Affiliation: Duksung Women's University
Country: Korea

Publications

  1. ncbi Chemopreventive allylthiopyridazines inhibit invasion, migration and angiogenesis in hepatocarcinoma cells
    Eun Jung Lee
    College of Pharmacy, Duksung Women s University, Seoul 132 714, Korea
    Int J Oncol 23:1645-50. 2003
  2. doi Global gene expression profiling unveils S100A8/A9 as candidate markers in H-ras-mediated human breast epithelial cell invasion
    Aree Moon
    College of Pharmacy, Duksung Women s University, Seoul, Korea
    Mol Cancer Res 6:1544-53. 2008
  3. ncbi Differential functions of Ras for malignant phenotypic conversion
    Aree Moon
    College of Pharmacy, Duksung Women s University, Seoul 132 714, Korea
    Arch Pharm Res 29:113-22. 2006
  4. ncbi H-Ras-specific activation of Rac-MKK3/6-p38 pathway: its critical role in invasion and migration of breast epithelial cells
    Ilchung Shin
    College of Pharmacy, Duksung Women s University, Seoul 132 714, Korea
    J Biol Chem 280:14675-83. 2005
  5. doi The G12 family proteins upregulate matrix metalloproteinase-2 via p53 leading to human breast cell invasion
    Eun Sook Kim
    College of Pharmacy, Duksung Women s University, Seoul, Korea
    Breast Cancer Res Treat 124:49-61. 2010
  6. ncbi ErbB2-enhanced invasiveness of H-Ras MCF10A breast cells requires MMP-13 and uPA upregulation via p38 MAPK signaling
    Hae Young Yong
    College of Pharmacy, Duksung Women s University, Seoul 132 714, Korea
    Int J Oncol 36:501-7. 2010
  7. ncbi Retroviral delivery of TIMP-2 inhibits H-ras-induced migration and invasion in MCF10A human breast epithelial cells
    Seong Min Ahn
    College of Pharmacy, Duksung Women s University, Seoul 132 714, South Korea
    Cancer Lett 207:49-57. 2004
  8. ncbi Glial cell-derived neurotrophic factor (GDNF) promotes low-grade Hs683 glioma cell migration through JNK, ERK-1/2 and p38 MAPK signaling pathways
    Hyun Song
    College of Pharmacy, Duksung Women s University, 419 Ssangmun dong, Dobong gu, Seoul, Republic of Korea
    Neurosci Res 56:29-38. 2006
  9. ncbi p38 kinase is a key signaling molecule for H-Ras-induced cell motility and invasive phenotype in human breast epithelial cells
    Mi Sung Kim
    College of Pharmacy, Duksung Women s University, Seoul 132 714, Korea
    Cancer Res 63:5454-61. 2003
  10. ncbi Roles of calcium-binding proteins, S100A8 and S100A9, in invasive phenotype of human gastric cancer cells
    Hae Young Yong
    College of Pharmacy, Duksung Women s University, Seoul 132 714, Korea
    Arch Pharm Res 30:75-81. 2007

Collaborators

  • Hyeong Reh Kim
  • Dong Young Noh
  • Soon Kyoung Kwon
  • Hyun Ju Moon
  • Y Surh
  • Jing Wang
  • So Yeon Park
  • Do Hyun Nam
  • Qian Zhang
  • Eun Jeong Lee
  • David Kaplan
  • Young Jin Chun
  • Keon Wook Kang
  • Jae Ho Shin
  • Sang Hyup Lee
  • S G Kim
  • Hea Soon Shin
  • Eun Sook Kim
  • Hae Young Yong
  • In Young Kim
  • Mi Sung Kim
  • Hyun Song
  • Soon Young Han
  • Min Soo Koh
  • Chang Ho Lee
  • Young Choong Kim
  • Dae Gyu Kim
  • You Rim Jeon
  • Minsoo Koh
  • So Jung Sohn
  • Yujin Cha
  • Jung Min Lee
  • Jae In Song
  • Choon Sik Jeong
  • Hyun Jung Park
  • Kyung Min Lee
  • Seong Min Ahn
  • Soouk Kang
  • Jung Hwan Kim
  • Youngju Choi
  • Sung Hwan Ki
  • Ki Won Lee
  • Seo Jin Jeong
  • Ilchung Shin
  • Il Hyun Kang
  • Kwang Sik Choi
  • Tae Sung Kim
  • Hye Jung Kang
  • Doyeun Kim
  • Young Ho Jeon
  • Kibom Kim
  • Jin Young Lee
  • Byung Woo Han
  • Jae Eun Joo
  • Ming wei Wang
  • Heekyoung Yang
  • Pengfei Fang
  • Youn Hur
  • Mi Sook Lee
  • Cheolju Lee
  • Ameeq Ul Mushtaq
  • Kyung Hee Rhee
  • Won Suk Yang
  • Youngji Moon
  • Jung Weon Lee
  • Jin Woo Choi
  • Eun Joo Kang
  • Jee Sun Yang
  • Wonyoung Kang
  • Min Guo
  • Gyoonhee Han
  • Nicolas L Young
  • Jung Min Han
  • Ho Woong Kang
  • Nam Hoon Kwon
  • Hye Young Cho
  • Yong Nyun Kim
  • Changhee Min
  • Jong Cheol Lee
  • Hee Yeon Kay
  • Youjin Kang
  • Yu Jin Kang
  • Woo Hyung Lee
  • Sejin Hwang
  • Do Kyun Kim
  • Bong Jin Lee
  • Wahn Soo Choi
  • Eok Soo Oh
  • Hae In Park
  • Jin Sun Hwang

Detail Information

Publications47

  1. ncbi Chemopreventive allylthiopyridazines inhibit invasion, migration and angiogenesis in hepatocarcinoma cells
    Eun Jung Lee
    College of Pharmacy, Duksung Women s University, Seoul 132 714, Korea
    Int J Oncol 23:1645-50. 2003
    ..Taken in conjunction with the fact that hepatocellular carcinoma is one of the most lethal malignancies, our findings may be critical to the chemopreventive potential of these synthetic organosulfur compounds for hepatocarcinoma...
  2. doi Global gene expression profiling unveils S100A8/A9 as candidate markers in H-ras-mediated human breast epithelial cell invasion
    Aree Moon
    College of Pharmacy, Duksung Women s University, Seoul, Korea
    Mol Cancer Res 6:1544-53. 2008
    ..Our gene profile data provide useful information which may lead to the identification of additional potential targets for the prognosis and/or therapy of metastatic breast cancer...
  3. ncbi Differential functions of Ras for malignant phenotypic conversion
    Aree Moon
    College of Pharmacy, Duksung Women s University, Seoul 132 714, Korea
    Arch Pharm Res 29:113-22. 2006
    ..In spite of the accumulation of information on the differential functions of Ras, much more remains to be elucidated to understand the Ras-mediated molecular events of malignant phenotypic conversion of cells in a greater detail...
  4. ncbi H-Ras-specific activation of Rac-MKK3/6-p38 pathway: its critical role in invasion and migration of breast epithelial cells
    Ilchung Shin
    College of Pharmacy, Duksung Women s University, Seoul 132 714, Korea
    J Biol Chem 280:14675-83. 2005
    ....
  5. doi The G12 family proteins upregulate matrix metalloproteinase-2 via p53 leading to human breast cell invasion
    Eun Sook Kim
    College of Pharmacy, Duksung Women s University, Seoul, Korea
    Breast Cancer Res Treat 124:49-61. 2010
    ....
  6. ncbi ErbB2-enhanced invasiveness of H-Ras MCF10A breast cells requires MMP-13 and uPA upregulation via p38 MAPK signaling
    Hae Young Yong
    College of Pharmacy, Duksung Women s University, Seoul 132 714, Korea
    Int J Oncol 36:501-7. 2010
    ....
  7. ncbi Retroviral delivery of TIMP-2 inhibits H-ras-induced migration and invasion in MCF10A human breast epithelial cells
    Seong Min Ahn
    College of Pharmacy, Duksung Women s University, Seoul 132 714, South Korea
    Cancer Lett 207:49-57. 2004
    ....
  8. ncbi Glial cell-derived neurotrophic factor (GDNF) promotes low-grade Hs683 glioma cell migration through JNK, ERK-1/2 and p38 MAPK signaling pathways
    Hyun Song
    College of Pharmacy, Duksung Women s University, 419 Ssangmun dong, Dobong gu, Seoul, Republic of Korea
    Neurosci Res 56:29-38. 2006
    ..Our findings revealing molecular mechanisms for the promoting effect of GDNF on glioma cell migration may provide an insight into a better understanding to the malignant progression of human gliomas...
  9. ncbi p38 kinase is a key signaling molecule for H-Ras-induced cell motility and invasive phenotype in human breast epithelial cells
    Mi Sung Kim
    College of Pharmacy, Duksung Women s University, Seoul 132 714, Korea
    Cancer Res 63:5454-61. 2003
    ..This study reveals the p38 kinase as a key signaling molecule differentially regulated by H-ras and N-ras, leading to H-ras-specific cell invasive and migrative phenotypes in human breast epithelial cells...
  10. ncbi Roles of calcium-binding proteins, S100A8 and S100A9, in invasive phenotype of human gastric cancer cells
    Hae Young Yong
    College of Pharmacy, Duksung Women s University, Seoul 132 714, Korea
    Arch Pharm Res 30:75-81. 2007
    ..Taken together, this study revealed a functional contribution of S100A8 and S100A9 proteins to processes required for malignant progression including invasion, migration and proteinase expression in SNU484 human gastric cancer cells...
  11. ncbi Simvastatin and lovastatin inhibit breast cell invasion induced by H-Ras
    Soouk Kang
    College of Pharmacy, Duksung Women s University, Seoul 132 714, Korea
    Oncol Rep 21:1317-22. 2009
    ....
  12. ncbi TGF-beta-induced upregulation of MMP-2 and MMP-9 depends on p38 MAPK, but not ERK signaling in MCF10A human breast epithelial cells
    Eun Sook Kim
    College of Pharmacy, Duksung Women s University, Seoul 132 714, Korea
    Int J Oncol 25:1375-82. 2004
    ....
  13. doi H-Ras-specific upregulation of granulocyte colony-stimulating factor promotes human breast cell invasion via matrix metalloproteinase-2
    Sunhwa Park
    College of Pharmacy, Duksung Women s University, Seoul, Republic of Korea
    Cytokine 55:126-33. 2011
    ..These data provide a molecular basis for the crucial role of G-CSF in promoting invasiveness of human breast epithelial cells...
  14. ncbi Pyrethroid insecticides, fenvalerate and permethrin, inhibit progesterone-induced alkaline phosphatase activity in T47D human breast cancer cells
    In Young Kim
    Department of Toxicology, National Institute of Toxicological Research, Seoul, Korea
    J Toxicol Environ Health A 68:2175-86. 2005
    ..Our data indicate that fenvalerate and permethrin exhibit antiprogestagenic activity in T47D human breast cancer cells...
  15. ncbi Activating transcription factor 2 mediates matrix metalloproteinase-2 transcriptional activation induced by p38 in breast epithelial cells
    Hyun Song
    College of Pharmacy, Duksung Women s University, Seoul National University, Seoul, Korea
    Cancer Res 66:10487-96. 2006
    ....
  16. ncbi TGF-beta-induced transcriptional activation of MMP-2 is mediated by activating transcription factor (ATF)2 in human breast epithelial cells
    Eun Sook Kim
    College of Pharmacy, Duksung Women s University, Seoul 132 714, Republic of Korea
    Cancer Lett 252:147-56. 2007
    ..Taken together, this study demonstrates that ATF2 mediates the TGF-beta-induced MMP-2 transcriptional activation, elucidating a molecular mechanism for the malignant progression of human breast epithelial cells exerted by TGF-beta...
  17. doi Overexpression of ErbB2 induces invasion of MCF10A human breast epithelial cells via MMP-9
    In Young Kim
    College of Pharmacy, Duksung Women s University, 419 Ssangmun dong, Tobong gu, Seoul, Republic of Korea
    Cancer Lett 275:227-33. 2009
    ..Given that ErbB2 is one of the most important oncogenes in human breast cancer and thus is an attractive therapeutic target, our findings may provide a molecular basis for the promoting role of ErbB2 in breast cancer progression...
  18. ncbi Identification of annexin II as a novel secretory biomarker for breast cancer
    You Rim Jeon
    College of Pharmacy, Duksung Women s University, Seoul, Korea
    Proteomics 13:3145-56. 2013
    ..Taken together, we identified annexin II as a novel secretory biomarker candidate for invasive breast cancer, especially estrogen receptor-negative breast cancer. ..
  19. ncbi Transforming growth factor (TGF)-beta in conjunction with H-ras activation promotes malignant progression of MCF10A breast epithelial cells
    Eun Sook Kim
    College of Pharmacy, Duksung Women s University, Seoul 132 714, Republic of Korea
    Cytokine 29:84-91. 2005
    ....
  20. ncbi Type I collagen-induced pro-MMP-2 activation is differentially regulated by H-Ras and N-Ras in human breast epithelial cells
    In Young Kim
    College of Pharmacy, Duksung Women s University, Seoul 132 714, Korea
    J Biochem Mol Biol 40:825-31. 2007
    ....
  21. doi Denbinobin, a phenanthrene from dendrobium nobile, inhibits invasion and induces apoptosis in SNU-484 human gastric cancer cells
    Jae In Song
    College of Pharmacy, Duksung Women s University, 419 Ssangmun dong, Seoul 132 714, Republic of Korea
    Oncol Rep 27:813-8. 2012
    ....
  22. doi Sphingosine 1-phosphate regulates matrix metalloproteinase-9 expression and breast cell invasion through S1P3-Gαq coupling
    Eun Sook Kim
    College of Pharmacy, Duksung Women s University, Seoul 132 714, Korea
    J Cell Sci 124:2220-30. 2011
    ....
  23. ncbi In vitro evaluation of biomarkers for cisplatin-induced nephrotoxicity using HK-2 human kidney epithelial cells
    So Jung Sohn
    College of Pharmacy, Duksung Women s University, Seoul 132 714, Republic of Korea
    Toxicol Lett 217:235-42. 2013
    ....
  24. doi Genipin, a constituent of Gardenia jasminoides Ellis, induces apoptosis and inhibits invasion in MDA-MB-231 breast cancer cells
    Eun Sook Kim
    College of Pharmacy, Duksung Women s University, Seoul, Republic of Korea
    Oncol Rep 27:567-72. 2012
    ....
  25. doi 2-Hydroxychalcone and xanthohumol inhibit invasion of triple negative breast cancer cells
    Sun Young Kim
    College of Pharmacy, Duksung Women s University, Seoul 132 714, Republic of Korea
    Chem Biol Interact 203:565-72. 2013
    ..These results suggest a potential application of these chalcones as anticancer agents that can alleviate malignant progression of TNBC...
  26. ncbi HER2 induces expression of leptin in human breast epithelial cells
    Yujin Cha
    College of Pharmacy, Duksung Women s University, Seoul 132 714, Korea
    BMB Rep 45:719-23. 2012
    ..Taken together, the results indicate a molecular link between HER2 and leptin, providing supporting evidence that leptin represents a target for breast cancer therapy. [BMB Reports 2012; 45(12): 719-723]...
  27. ncbi Capsaicin-induced apoptosis of H-ras-transformed human breast epithelial cells is Rac-dependent via ROS generation
    Seonhoe Kim
    College of Pharmacy, Duksung Women s University, Seoul 132 714, Korea
    Arch Pharm Res 27:845-9. 2004
    ....
  28. ncbi Regulation of matrix metalloproteinases and invasion by G(alpha12/13) proteins in NIH3T3 mouse fibroblast cells
    Eun Sook Kim
    College of Pharmacy, Duksung Women s University, Seoul, Korea
    Oncol Res 19:297-301. 2011
    ..Taken together, this study elucidated the role of Galpha12/13 in regulating malignant phenotypic conversion of NIH3T3 fibroblast cells, validating the role of Galphal2/13 in tumorigenesis...
  29. ncbi Synthesis of 3-alkylthio-6-allylthiopyridazine derivatives and their antihepatocarcinoma activity
    Soon Kyoung Kwon
    College of Pharmacy, Duksung Women s University, Seoul 132 714, Korea
    Arch Pharm Res 28:391-4. 2005
    ..Thio-K6, one of the sulfur-substituted compounds, showed better chemopreventive activity toward hepatocarcinoma cells...
  30. doi The p38 MAPK inhibitors for the treatment of inflammatory diseases and cancer
    Hae Young Yong
    Duksung Women s University, College of Pharmacy, Seoul, Korea
    Expert Opin Investig Drugs 18:1893-905. 2009
    ....
  31. doi Hemin, an iron-binding porphyrin, inhibits HIF-1α induction through its binding with heat shock protein 90
    Jung Min Lee
    College of Pharmacy and Research Institute of Pharmaceutical Sciences, Seoul National University, Seoul, Korea
    Int J Cancer 130:716-27. 2012
    ....
  32. pmc Identification of H-Ras-specific motif for the activation of invasive signaling program in human breast epithelial cells
    Hae Young Yong
    College of Pharmacy, Duksung Women s University, Seoul, South Korea
    Neoplasia 13:98-107. 2011
    ....
  33. ncbi G alpha 12/13 basally regulates p53 through Mdm4 expression
    Mi Sung Kim
    College of Pharmacy and Research Institute of Pharmaceutical Sciences, Seoul National University, Seoul, Korea
    Mol Cancer Res 5:473-84. 2007
    ..Our results indicate that G alpha(12/13) regulate basal p53 levels via mdm4, which constitutes a cell signaling pathway distinct from p53 phosphorylations elicited by genotoxic stress...
  34. ncbi Assessing estrogenic activity of pyrethroid insecticides using in vitro combination assays
    In Young Kim
    Endocrine Toxicology Division, National Institute of Toxicological Research, Korea Food and Drug Administration, Seoul, Korea
    J Reprod Dev 50:245-55. 2004
    ..These results suggest that certain pyrethroid insecticides may be considered to be estrogen-like chemicals that act through pathways other than direct ER binding, and may function as endocrine modulators in both wildlife and humans...
  35. ncbi Phthalates inhibit tamoxifen-induced apoptosis in MCF-7 human breast cancer cells
    In Young Kim
    College of Pharmacy, Duksung Women s University, Seoul, Korea
    J Toxicol Environ Health A 67:2025-35. 2004
    ..Given that the phthalates are widely used in cosmetics mainly for women, our findings that revealed the promoting effect of BBP, DBP, and DEHP on chemotherapeutic drug resistance to TAM in breast cancer may be of biological relevance...
  36. ncbi Roles of JNK-1 and p38 in selective induction of apoptosis by capsaicin in ras-transformed human breast epithelial cells
    Hye Jung Kang
    College of Pharmacy, Duksung Women s University, 4129 Ssangmun dong, Tobong ku, Seoul 132 714, Korea
    Int J Cancer 103:475-82. 2003
    ....
  37. doi Activation of H-Ras and Rac1 correlates with epidermal growth factor-induced invasion in Hs578T and MDA-MB-231 breast carcinoma cells
    Min Soo Koh
    College of Pharmacy, Duksung Women s University, Seoul 132 714, Republic of Korea
    Biochem Biophys Res Commun 406:25-9. 2011
    ....
  38. ncbi A novel metformin derivative, HL010183, inhibits proliferation and invasion of triple-negative breast cancer cells
    Minsoo Koh
    College of Pharmacy, Duksung Women s University, Seoul 132 714, Republic of Korea
    Bioorg Med Chem 21:2305-13. 2013
    ..Our results clearly demonstrate that 5 exerts a potent anti-tumor effect both in vitro and in vivo, paving the way for a strategy for treatment of triple-negative breast cancer...
  39. ncbi In vitro bioassay for transforming growth factor-beta using XTT method
    Mi Sung Kim
    College of Pharmacy, Duksung Womens University, Seoul 132 714, Korea
    Arch Pharm Res 25:903-9. 2002
    ..Our results may contribute to the establishment of an in vitro bioassay system, which could be used for the satisfactory quantitation of TGF-beta...
  40. pmc Chemical inhibition of prometastatic lysyl-tRNA synthetase-laminin receptor interaction
    Dae Gyu Kim
    1 Medicinal Bioconvergence Research Center, Seoul National University, Seoul, Korea 2 Research Institute of Pharmaceutical Sciences, College of Pharmacy, Seoul National University, Seoul, Korea 3
    Nat Chem Biol 10:29-34. 2014
    ..Our results suggest that specific modulation of a cancer-related KRS-67LR interaction may offer a way to control metastasis while avoiding the toxicities associated with inhibition of the normal functions of KRS...
  41. doi Synthesis and mechanistic studies of a mitomycin dimer containing an eight-membered cyclic disulfide
    Hyun Jung Park
    College of Pharmacy, Duksung Women s University, Seoul, Republic of Korea
    Bioorg Med Chem 19:4004-13. 2011
    ....
  42. ncbi Sauchinone, a lignan from Saururus chinensis, inhibits staurosporine-induced apoptosis in C6 rat glioma cells
    Hyun Song
    College of Pharmacy, Duksung Women s University, Seoul, Korea
    Biol Pharm Bull 26:1428-30. 2003
    ..Our findings may be critical for developing a strategy to protect nerve cells from apoptosis, suggesting the potential development of sauchinone as a neuroprotective agent...
  43. ncbi H-Ras selectively up-regulates MMP-9 and COX-2 through activation of ERK1/2 and NF-kappaB: an implication for invasive phenotype in rat liver epithelial cells
    Ki Won Lee
    Department of Food Biotechnology, School of Agricultural Biotechnology, Seoul National University, Seoul, South Korea
    Int J Cancer 119:1767-75. 2006
    ....
  44. ncbi Roles of ERK and p38 mitogen-activated protein kinases in phorbol ester-induced NF-kappaB activation and COX-2 expression in human breast epithelial cells
    Jung Hwan Kim
    National Research Laboratory of Molecular Carcinogenesis and Chemoprevention, College of Pharmacy, Seoul National University, Seoul 151 742, South Korea
    Chem Biol Interact 171:133-41. 2008
    ..These results suggest that both p38 and ERK MAPKs activates NF-kappaB signaling, which in turn induces COX-2 expression in TPA-stimulated human mammary epithelial cells...
  45. doi A pinusolide derivative, 15-methoxypinusolidic acid from Biota orientalis inhibits inducible nitric oxide synthase in microglial cells: implication for a potential anti-inflammatory effect
    Youngju Choi
    College of Pharmacy, Seoul National University, 599 Gwanangno, Gwanak Gu, Seoul 151 742, Republic of Korea
    Int Immunopharmacol 8:548-55. 2008
    ..Taken together, this study demonstrates that 15-MPA inhibits LPS-induced iNOS expression and NO production, independent on MAPK and NF-kappaB, suggesting a potential anti-inflammatory effect of the compound on microglial cells...