Tae Jung Jang

Summary

Affiliation: Dongguk University
Country: Korea

Publications

  1. doi request reprint O-GlcNAcylation is associated with the development and progression of gastric carcinoma
    Tae Jung Jang
    Department of Pathology, Dongguk University College of Medicine, Gyeongju, Republic of Korea Electronic address
    Pathol Res Pract 212:622-30. 2016
  2. doi request reprint Differential membranous E-cadherin expression, cell proliferation and O-GlcNAcylation between primary and metastatic nodal lesion in colorectal cancer
    Tae Jung Jang
    Department of Pathology, Dongguk University College of Medicine, Gyongju, Korea Electronic address
    Pathol Res Pract 212:113-9. 2016
  3. pmc Sulindac prevents esophageal adenocarcinomas induced by gastroduodenal reflux in rats
    Sung Wook Kim
    Departments of Gastroenterology, Dongguk University College of Medicine, Kyongju, Korea
    Yonsei Med J 48:1020-7. 2007
  4. pmc CD10 Is Again Expressed at a Certain Stage during the Neoplastic Process of Bladder Transitional Cell Carcinomas
    Tae Jung Jang
    Department of Pathology, Dongguk University College of Medicine, Gyeongju, Korea
    Cancer Res Treat 44:262-6. 2012
  5. pmc The expression of pigment epithelium-derived factor in bladder transitional cell carcinoma
    Tae Jung Jang
    Department of Pathology, Dongguk University College of Medicine, Gyeongju, Korea
    Korean J Pathol 46:261-5. 2012
  6. pmc Prostaglandin E(2) and interleukin-1β reduce E-cadherin expression by enhancing snail expression in gastric cancer cells
    Ye Seob Jee
    Department of Surgery, Dankook University Hospital, Cheonan, Korea
    J Korean Med Sci 27:987-92. 2012
  7. doi request reprint Epithelial to mesenchymal transition in cutaneous squamous cell carcinoma is correlated with COX-2 expression but not with the presence of stromal macrophages or CD10-expressing cells
    Tae Jung Jang
    Department of Pathology, Dongguk University College of Medicine, Sukjang dong 707, Gyeongju, Gyeongbuk 780 714, South Korea
    Virchows Arch 460:481-7. 2012
  8. ncbi request reprint Increased expression of cyclin D1, cyclin E and p21(Cip1) associated with decreased expression of p27(Kip1) in chemically induced rat mammary carcinogenesis
    T J Jang
    Department of Pathology, Dongguk University College of Medicine, Sukjang Dong, Kyongju, Kyongbuk 780 714, Korea
    Jpn J Cancer Res 91:1222-32. 2000
  9. doi request reprint Reciprocal correlation between the expression of cyclooxygenase-2 and E-cadherin in human bladder transitional cell carcinomas
    Tae Jung Jang
    Department of Pathology, College of Medicine, Dongguk University, Gyeongju, Gyeongbuk 780 714, South Korea
    Virchows Arch 457:319-28. 2010
  10. pmc Cyclooxygenase-2 expression is related to the epithelial-to-mesenchymal transition in human colon cancers
    Tae Jung Jang
    Department of Pathology, Dongguk University College of Medicine, Gyeongju, Korea
    Yonsei Med J 50:818-24. 2009

Collaborators

Detail Information

Publications33

  1. doi request reprint O-GlcNAcylation is associated with the development and progression of gastric carcinoma
    Tae Jung Jang
    Department of Pathology, Dongguk University College of Medicine, Gyeongju, Republic of Korea Electronic address
    Pathol Res Pract 212:622-30. 2016
    ..This reaction, which is catalyzed by O-GlcNAc-transferase (OGT), is involved in a variety of human cancers; however, its clinical significance in gastric carcinomas (GC) has been poorly investigated in vivo...
  2. doi request reprint Differential membranous E-cadherin expression, cell proliferation and O-GlcNAcylation between primary and metastatic nodal lesion in colorectal cancer
    Tae Jung Jang
    Department of Pathology, Dongguk University College of Medicine, Gyongju, Korea Electronic address
    Pathol Res Pract 212:113-9. 2016
    ..In addition, the cliniopathological significance of O-GlcNAcylation was studied..
  3. pmc Sulindac prevents esophageal adenocarcinomas induced by gastroduodenal reflux in rats
    Sung Wook Kim
    Departments of Gastroenterology, Dongguk University College of Medicine, Kyongju, Korea
    Yonsei Med J 48:1020-7. 2007
    ..We studied COX-2 expression and the effect sulindac has on the genesis of Barrett's esophagus and adenocarcinoma in rats undergoing esophagogastroduodenal anastomosis (EGDA)...
  4. pmc CD10 Is Again Expressed at a Certain Stage during the Neoplastic Process of Bladder Transitional Cell Carcinomas
    Tae Jung Jang
    Department of Pathology, Dongguk University College of Medicine, Gyeongju, Korea
    Cancer Res Treat 44:262-6. 2012
    ..The aim of this study is to examine any association between CD10 expression and clinicopathological parameters in bladder transitional cell carcinomas (TCCs) and the relationship between expression of E-cadherin and CD10...
  5. pmc The expression of pigment epithelium-derived factor in bladder transitional cell carcinoma
    Tae Jung Jang
    Department of Pathology, Dongguk University College of Medicine, Gyeongju, Korea
    Korean J Pathol 46:261-5. 2012
    ..Pigment epithelium-derived factor (PEDF) is an anti-angiogenic factor. The purpose of this study is to examine the involvement of PEDF in the angiogenesis and biological behavior of bladder transitional cell carcinoma (TCC)...
  6. pmc Prostaglandin E(2) and interleukin-1β reduce E-cadherin expression by enhancing snail expression in gastric cancer cells
    Ye Seob Jee
    Department of Surgery, Dankook University Hospital, Cheonan, Korea
    J Korean Med Sci 27:987-92. 2012
    ..Inflammation-induced transcriptional regulation of E-cadherin in gastric cancer has implications for targeted chemoprevention and therapy...
  7. doi request reprint Epithelial to mesenchymal transition in cutaneous squamous cell carcinoma is correlated with COX-2 expression but not with the presence of stromal macrophages or CD10-expressing cells
    Tae Jung Jang
    Department of Pathology, Dongguk University College of Medicine, Sukjang dong 707, Gyeongju, Gyeongbuk 780 714, South Korea
    Virchows Arch 460:481-7. 2012
    ..We suggest that cutaneous SCC cells show EMT, which appears to be correlated with COX-2 expression but not with stromal CD10 expression and TAM...
  8. ncbi request reprint Increased expression of cyclin D1, cyclin E and p21(Cip1) associated with decreased expression of p27(Kip1) in chemically induced rat mammary carcinogenesis
    T J Jang
    Department of Pathology, Dongguk University College of Medicine, Sukjang Dong, Kyongju, Kyongbuk 780 714, Korea
    Jpn J Cancer Res 91:1222-32. 2000
    ..Our results suggest that rat mammary carcinogenesis involves increased expression of cyclin D1, cyclin E, and p21(Cip1), associated with decreased expression of p27(Kip1)...
  9. doi request reprint Reciprocal correlation between the expression of cyclooxygenase-2 and E-cadherin in human bladder transitional cell carcinomas
    Tae Jung Jang
    Department of Pathology, College of Medicine, Dongguk University, Gyeongju, Gyeongbuk 780 714, South Korea
    Virchows Arch 457:319-28. 2010
    ..We suggest that COX-2 pathway reduces membranous E-cadherin expression in bladder TCCs and their expression pattern may provide important information in predicting the clinical behavior of bladder TCCs...
  10. pmc Cyclooxygenase-2 expression is related to the epithelial-to-mesenchymal transition in human colon cancers
    Tae Jung Jang
    Department of Pathology, Dongguk University College of Medicine, Gyeongju, Korea
    Yonsei Med J 50:818-24. 2009
    ..Cyclooxygenase-2 (COX-2) expression is associated with tumor invasion and metastasis in colon cancer. This study investigated the relationship between E-cadherin and COX-2 in colon cancer cells and human colon tumors...
  11. doi request reprint The number of Foxp3-positive regulatory T cells is increased in Helicobacter pylori gastritis and gastric cancer
    Tae Jung Jang
    Department of Pathology, Dongguk University College of Medicine, Sukjang dong 707, Kyongju, Kyongbuk 780 714, Republic of Korea
    Pathol Res Pract 206:34-8. 2010
    ..It was significantly elevated in adenocarcinomas compared to chronic gastritis and gastric dysplasia. In summary, the number of Tregs is increased in H. pylori-associated gastritis and gastric cancer...
  12. pmc Prevalence of Foxp3 positive T regulatory cells is increased during progression of cutaneous squamous tumors
    Tae Jung Jang
    Department of Pathology, Dongguk University College of Medicine, 707 Sukjang dong, Kyongju, Kyongbuk 780 714, Korea
    Yonsei Med J 49:942-8. 2008
    ..The aim of this study is to evaluate the prevalence of Tregs and DCs infiltration in cutaneous premalignant and malignant squamous lesions...
  13. pmc Decreased expression of 15-hydroxyprostaglandin dehydrogenase in gastric carcinomas
    Tae Jung Jang
    Department of Pathology, Dongguk University College of Medicine, 707 Sukjang dong, Kyongju, Kyongbuk 780 714, Korea
    Yonsei Med J 49:917-22. 2008
    ..However, little is known about the expression of 15-hydroxyprostaglandin dehydrogenase (15-PGDH), the key enzyme responsible for the biological inactivation of PG, in gastric carcinomas...
  14. ncbi request reprint Proapoptotic activity of NAG-1 is cell type specific and not related to COX-2 expression
    Tae Jung Jang
    Department of Pathology, Dongguk University College of Medicine, Suek jang Dong 707, Kyongju, Kyongbuk 780 714, Korea
    Apoptosis 11:1131-8. 2006
    ..This study suggests that proapoptotic activity of NAG-1 is cell type specific and not related to COX-2 expression...
  15. pmc Expression of cyclooxygenase 2, microsomal prostaglandin E synthase 1, and EP receptors is increased in rat oesophageal squamous cell dysplasia and Barrett's metaplasia induced by duodenal contents reflux
    T J Jang
    Department of Pathology, Dongguk University College of Medicine, Kyongju, Kyongbuk, Korea
    Gut 53:27-33. 2004
    ..Therefore, we examined the expression pattern of cyclooxygenase 1 (COX-1), COX-2, and microsomal prostaglandin E synthase 1 (mPGES-1), as well as EP receptor subtypes in rat oesophageal lesions induced by duodenal contents reflux...
  16. ncbi request reprint Adherence of Helicobacter pylori to areas of type II intestinal metaplasia in Korean gastric mucosa
    T J Jang
    Department of Pathology, Dongguk University College of Medicine, Kyongju, Korea
    Yonsei Med J 40:392-5. 1999
    ..All areas of intestinal metaplasia showing adherence contained sialomucin, and H. pylori was not detected in the areas of intestinal absorptive cells and sulfomucin-containing metaplastic cells...
  17. ncbi request reprint Chemically induced rat mammary tumor treated with tamoxifen showed decreased expression of cyclin D1, cyclin E, and p21(Cip1)
    T J Jang
    Department of Pathology, Dongguk University College of Medicine, 707, Sukjang Dong, Kyongju, Kyongbuk 780 714, South Korea
    Cancer Lett 170:109-16. 2001
    ..These tumors had decreased expression of ER. This study suggests that TAM suppresses tumor development through the down-expression of cyclin D1 and cyclin E...
  18. ncbi request reprint p16(INK4a) Promoter hypermethylation of non-tumorous tissue adjacent to gastric cancer is correlated with glandular atrophy and chronic inflammation
    T J Jang
    Department of Pathology, Dongguk University College of Medicine, Kyongju, Kyongbuk, Korea
    Int J Cancer 93:629-34. 2001
    ..These results suggest that p16(INK4a) promoter hypermethylation is an early and frequent event in gastric carcinogenesis and may serve as a new prognostic biomarker for the risk of gastric cancers...
  19. ncbi request reprint Inducible nitric oxide synthase expression of tumor and stromal cells is associated with the progression of 7,12-dimethylbenz[a]anthracene-induced rat mammary tumors
    Tae Jung Jang
    Department of Pathology, Dongguk University College of Medicine, 707 Sukjang dong, Kyongju, 780 714, Kyongbuk, South Korea
    Cancer Lett 182:121-6. 2002
    ..Stromal iNOS expression was correlated with apoptotic count. These results suggest that iNOS expression of tumor and stromal cells is associated with the progression of DMBA-induced rat mammary tumors...
  20. ncbi request reprint Expression of CD40 and Fas ligand in Bowen's disease, squamous cell carcinoma and basal cell carcinoma
    Tae Jung Jang
    Department of Pathology, Dongguk University College of Medicine, 707 Sukjang dong, Kyongju, Kyongbuk 780 714, Korea
    Yonsei Med J 43:304-8. 2002
    ..These results suggest that altered CD40 and FasL expression may be related with the progression of SCC, and the marked reduced expression of CD40 and FasL may explain the biologic behavior of BCCs...
  21. ncbi request reprint Reflux esophagitis facilitates low Helicobacter pylori infection rate and gastric inflammation
    Tae Jung Jang
    Department of Pathology, Dongguk University College of Medicine, Kyongbuk, Korea
    J Gastroenterol Hepatol 17:839-43. 2002
    ..pylori infection and reflux esophagitis. Therefore, an investigation was undertaken in Korean subjects regarding the incidence of H. pylori infection, and a histopathological study of reflux esophagitis was also carried out...
  22. pmc Chemopreventive effect of celecoxib and expression of cyclooxygenase-1 and cyclooxygenase-2 on chemically-induced rat mammary tumours
    Tae Jung Jang
    Department of Pathology, Dongguk University College of Medicine, Kyongju, Kyongbuk, Korea
    Int J Exp Pathol 83:173-82. 2002
    ..In addition, we reconfirm that celecoxib reduces the growth of DMBA-induced rat mammary tumours...
  23. ncbi request reprint Carditis is associated with Helicobacter pylori-induced gastritis and not reflux esophagitis
    Tae Jung Jang
    Department of Pathology, Dongguk University College of Medicine, 707 Sukjang dong, Kynogju, Kyongbuk 780 714, Korea
    J Clin Gastroenterol 36:26-9. 2003
    ..In conclusion, -induced pangastritis may lead to the development of carditis, which is associated with occurrence of cardiac-type mucosa at the cardiac region...
  24. ncbi request reprint Non-steroidal anti-inflammatory drug activated gene (NAG-1) expression is closely related to death receptor-4 and -5 induction, which may explain sulindac sulfide induced gastric cancer cell apoptosis
    Tae Jung Jang
    Department of Pathology, Dongguk University College of Medicine, Suek jang Dong 707, Kyongju, Kyongbuk 780 714, Korea
    Carcinogenesis 25:1853-8. 2004
    ..We conclude that NAG-1 expression is closely related to DR-4 and DR-5 induction, which could provide a mechanistic basis for the apoptotic effect of COX inhibitors in gastric cancer cells...
  25. ncbi request reprint Expression of proteins related to prostaglandin E2 biosynthesis is increased in human gastric cancer and during gastric carcinogenesis
    Tae Jung Jang
    Department of Pathology, Dongguk University College of Medicine, Suek jang Dong 707, Kyongju, 780 714 Kyongbuk, Korea
    Virchows Arch 445:564-71. 2004
    ..In conclusion, proteins related to PGE2 biosynthesis affect both histogenesis and the carcinogenesis of human gastric cancer...
  26. ncbi request reprint Cyclooxygenase-2 expression and cell proliferation are increased in MUC2-positive area of columnar-lined esophagus
    Tae Jung Jang
    Department of Pathology, Dongguk University College of Medicine, Kyongbuk, Korea
    Pathol Int 55:546-9. 2005
    ..In conclusion, intestinal-type columnar-lined esophagus possesses COX-2 expression and a higher proliferation potential, suggesting that esophageal adenocarcinoma may arise from specialized columnar-lined esophagus...
  27. ncbi request reprint Id-1 gene downregulation by sulindac sulfide and its upregulation during tumor development in gastric cancer
    Tae Jung Jang
    Department of Pathology, Dongguk University College of Medicine, Kyongju, Kyongbuk 780 714, South Korea
    Int J Cancer 118:1356-63. 2006
    ..Id-1, one of the repressed genes, is upregulated in gastric cancers and has positive role in tumor progression and histogenesis of intestinal-type cancers...
  28. pmc Cyclooxygenase-2 expression and effect of celecoxib in flurothyl-induced neonatal seizure
    Doo Kwun Kim
    Department of Pediatrics, and Department of Pathology, Dongguk University College of Medicine, Kyongju, Kyongbuk, Korea
    Int J Exp Pathol 87:73-8. 2006
    ....
  29. pmc Expression of inducible nitric oxide synthase is increased in rat Barrett's esophagus induced by duodenal contents reflux
    Jong Dae Bae
    Department of Surgery, Dongguk University College of Medicine, Kyoungju, Korea
    J Korean Med Sci 20:56-60. 2005
    ..iNOS mRNA was detected only in the lower esophagus of experimental group. In conclusion, this study suggests that iNOS has some roles on Barrett's esophagus formation...
  30. ncbi request reprint Increased expression of N-methyl-D-aspartate receptor subunit 2D in the skin of patients with fibromyalgia
    Seong Ho Kim
    Department of Internal Medicine, Dongguk University College of Medicine, Gyeongju, Gyeongbuk, Republic of Korea
    J Rheumatol 33:785-8. 2006
    ..We studied the expression of N-methyl-D-aspartate receptors (NMDAR) in skin of patients with fibromyalgia (FM) to investigate their role...
  31. pmc The breakdown of preformed peritoneal advanced glycation end products by intraperitoneal alagebrium
    Yong Kook Lee
    Department of Internal Medicine, Dongguk University Medical Center, Gyeongju, Korea
    J Korean Med Sci 24:S189-94. 2009
    ..These results suggest that the alagebrium may be the optimal therapeutic approach, compared with treatment with inhibitors of AGE formation, in rats on PD...