Gun Il Im
Affiliation: Dongguk University International Hospital
Im G, Lim M. Proximal hip geometry and hip fracture risk assessment in a Korean population. Osteoporos Int. 2011;22:803-7 pubmed publisher
..Our study showed that some PFG parameters as well as BMD values predict hip fractures in a Korean population, and their evaluation may be useful in the understanding of the biomechanics of hip fractures. ..
Im G, Lee J, Kim H. Wnt inhibitors enhance chondrogenesis of human mesenchymal stem cells in a long-term pellet culture. Biotechnol Lett. 2011;33:1061-8 pubmed publisher
..05) while SOX-9 and type X collagen protein expression was unaffected. These findings suggest that Wnt inhibitors promote the chondrogenic differentiation of hMSCs when treated for three weeks. ..
Kang M, Ko J, Kim J, Im G. Intra-articular delivery of kartogenin-conjugated chitosan nano/microparticles for cartilage regeneration. Biomaterials. 2014;35:9984-9994 pubmed publisher
..In conclusion, CHI-KGN NPs or CHI-KGN MPs can be useful polymer-drug conjugates as an IA drug delivery system to treat OA. ..
Im G, Shin K. Epigenetic approaches to regeneration of bone and cartilage from stem cells. Expert Opin Biol Ther. 2015;15:181-93 pubmed publisher
..Inhibition of PcG protein enhancer of zeste (Ezh2) a chromatin modifier, could be a promising candidate to improve MSC differentiation by decreasing Ezh2-mediated H3K27me3. ..
Ko J, Im G. Chondrogenic and Osteogenic Induction from iPS Cells. Methods Mol Biol. 2016;1357:441-50 pubmed publisher
..The authors developed protocol to examine the in vitro chondrogenesis and osteogenesis from hiPSCs and in vivo cartilage and bone regeneration using animal models. ..
Im G. Tissue Engineering in Osteoarthritis: Current Status and Prospect of Mesenchymal Stem Cell Therapy. BioDrugs. 2018;32:183-192 pubmed publisher
..Further radiological and histological data will be needed, with a larger pool of patients, before this question can be answered. ..
Kang M, Im G. Drug delivery systems for intra-articular treatment of osteoarthritis. Expert Opin Drug Deliv. 2014;11:269-82 pubmed publisher
..Future innovations in this field should be directed toward the development of adapted delivery systems that can induce tissue regeneration in OA patients. ..
Lee J, Ryu J, Kim E, Jo S, Kim B, Lee H, et al
. Adhesive barrier/directional controlled release for cartilage repair byÂ endogenous progenitor cell recruitment. Biomaterials. 2015;39:173-81 pubmed publisher
..This CHI-C barrier is expected to make a significant contribution in cartilage tissue engineering without cell transplantation as well as application for other tissue engineering. ..
Im G, Kim M. The relationship between osteoarthritis and osteoporosis. J Bone Miner Metab. 2014;32:101-9 pubmed publisher
..Low BMD at the lumbar spine is associated with a lower incidence of knee OA although it does not arrest the progression of knee OA. ..