Longzhen Piao

Summary

Affiliation: College of Medicine
Country: Korea

Publications

  1. pmc Heat shock protein 70-mediated sensitization of cells to apoptosis by Carboxyl-Terminal Modulator Protein
    Longzhen Piao
    Department of Pharmacology, Daejeon Regional Cancer Center, Cancer Research Institute, Research Institute for Medical Sciences, College of Medicine, Chungnam National University, Taejeon, 301 131, Korea
    BMC Cell Biol 10:53. 2009
  2. doi request reprint Regulation of OPA1-mediated mitochondrial fusion by leucine zipper/EF-hand-containing transmembrane protein-1 plays a role in apoptosis
    Longzhen Piao
    Department of Pharmacology, Daejeon Regional Cancer Center, Cancer Research Institute, Research Institute for Medical Sciences, College of Medicine, Chungnam National University, Taejeon, 301 131, Republic of Korea
    Cell Signal 21:767-77. 2009
  3. ncbi request reprint Phorbol 12-myristate 13-acetate protects against tumor necrosis factor (TNF)-induced necrotic cell death by modulating the recruitment of TNF receptor 1-associated death domain and receptor-interacting protein into the TNF receptor 1 signaling complex: Im
    Hee Sun Byun
    Department of Pharmacology, College of Medicine, Chungnam National University, 6 Munhwa dong, Jung Gu, Daejeon 301 131, Korea
    Mol Pharmacol 70:1099-108. 2006
  4. doi request reprint Association of LETM1 and MRPL36 contributes to the regulation of mitochondrial ATP production and necrotic cell death
    Longzhen Piao
    Department of Pharmacology, Daejeon Regional Cancer Center, Cancer Research Institute, Research Institute for Medical Sciences, South Korea
    Cancer Res 69:3397-404. 2009
  5. ncbi request reprint Regulation of 3-phosphoinositide-dependent protein kinase-1 (PDK1) by Src involves tyrosine phosphorylation of PDK1 and Src homology 2 domain binding
    Keum Jin Yang
    Department of Pharmacology, Daejeon Regional Cancer Center, Cancer Research Institute, Chungnam National University, 6 Munhwa dong, Jung Gu, Taejeon 301 131, South Korea
    J Biol Chem 283:1480-91. 2008
  6. pmc Prevention of TNF-induced necrotic cell death by rottlerin through a Nox1 NADPH oxidase
    Hee Sun Byun
    Department of Pharmacology, Research Institute for Medical Science, Infection Signaling Network Research Center, College of Medicine, Chungnam National University, Daejeon 301 131, Korea
    Exp Mol Med 40:186-95. 2008
  7. doi request reprint PKB-mediated PHF20 phosphorylation on Ser291 is required for p53 function in DNA damage
    Yuwen Li
    Department of Pharmacology, Metabolic Diseases and Cell Signaling Laboratory, Cancer Research Institute, Research Institute for Medical Sciences, College of Medicine, Chungnam National University, Daejeon, 301 131, South Korea
    Cell Signal 25:74-84. 2013
  8. ncbi request reprint Sustained activation of protein kinase C downregulates nuclear factor-kappaB signaling by dissociation of IKK-gamma and Hsp90 complex in human colonic epithelial cells
    Kyeong Ah Park
    Department of Pharmacology, Cancer Research Institute, College of Medicine, Chungnam National University, 6 Munhwa dong, Jung Gu, Daejeon 301 131, Korea
    Carcinogenesis 28:71-80. 2007

Collaborators

Detail Information

Publications8

  1. pmc Heat shock protein 70-mediated sensitization of cells to apoptosis by Carboxyl-Terminal Modulator Protein
    Longzhen Piao
    Department of Pharmacology, Daejeon Regional Cancer Center, Cancer Research Institute, Research Institute for Medical Sciences, College of Medicine, Chungnam National University, Taejeon, 301 131, Korea
    BMC Cell Biol 10:53. 2009
    ..In the present study we investigate novel mechanisms by which CTMP plays a role in apoptosis process...
  2. doi request reprint Regulation of OPA1-mediated mitochondrial fusion by leucine zipper/EF-hand-containing transmembrane protein-1 plays a role in apoptosis
    Longzhen Piao
    Department of Pharmacology, Daejeon Regional Cancer Center, Cancer Research Institute, Research Institute for Medical Sciences, College of Medicine, Chungnam National University, Taejeon, 301 131, Republic of Korea
    Cell Signal 21:767-77. 2009
    ..Taken together, these data suggest that LETM1 is a novel binding partner for CTMP that may play an important role in mitochondrial fragmentation via OPA1-cleavage...
  3. ncbi request reprint Phorbol 12-myristate 13-acetate protects against tumor necrosis factor (TNF)-induced necrotic cell death by modulating the recruitment of TNF receptor 1-associated death domain and receptor-interacting protein into the TNF receptor 1 signaling complex: Im
    Hee Sun Byun
    Department of Pharmacology, College of Medicine, Chungnam National University, 6 Munhwa dong, Jung Gu, Daejeon 301 131, Korea
    Mol Pharmacol 70:1099-108. 2006
    ..Taken together, these results suggest that PKC activation ensures effective shutdown of the death receptor-mediated necrotic cell death pathway by modulating formation of the death receptor signaling complex...
  4. doi request reprint Association of LETM1 and MRPL36 contributes to the regulation of mitochondrial ATP production and necrotic cell death
    Longzhen Piao
    Department of Pharmacology, Daejeon Regional Cancer Center, Cancer Research Institute, Research Institute for Medical Sciences, South Korea
    Cancer Res 69:3397-404. 2009
    ..The increased expression of LETM1 in human cancer suggests that dysregulation of LETM1 is a key feature of tumorigenesis...
  5. ncbi request reprint Regulation of 3-phosphoinositide-dependent protein kinase-1 (PDK1) by Src involves tyrosine phosphorylation of PDK1 and Src homology 2 domain binding
    Keum Jin Yang
    Department of Pharmacology, Daejeon Regional Cancer Center, Cancer Research Institute, Chungnam National University, 6 Munhwa dong, Jung Gu, Taejeon 301 131, South Korea
    J Biol Chem 283:1480-91. 2008
    ..Furthermore, Tyr(9) phosphorylation is critical for the stabilization of both PDK1 and the PDK1/Src complex via Hsp90-mediated protection of PDK1 degradation...
  6. pmc Prevention of TNF-induced necrotic cell death by rottlerin through a Nox1 NADPH oxidase
    Hee Sun Byun
    Department of Pharmacology, Research Institute for Medical Science, Infection Signaling Network Research Center, College of Medicine, Chungnam National University, Daejeon 301 131, Korea
    Exp Mol Med 40:186-95. 2008
    ..Therefore, our study suggests that Nox1 NADPH oxidase is a new molecular target for anti-necrotic activity of rottlerin upon death-receptor ligation...
  7. doi request reprint PKB-mediated PHF20 phosphorylation on Ser291 is required for p53 function in DNA damage
    Yuwen Li
    Department of Pharmacology, Metabolic Diseases and Cell Signaling Laboratory, Cancer Research Institute, Research Institute for Medical Sciences, College of Medicine, Chungnam National University, Daejeon, 301 131, South Korea
    Cell Signal 25:74-84. 2013
    ..Taken together, these data suggest that PHF20 is a novel substrate for PKB and its phosphorylation by PKB plays an important role in tumorigenesis via regulating of p53 mediated signaling...
  8. ncbi request reprint Sustained activation of protein kinase C downregulates nuclear factor-kappaB signaling by dissociation of IKK-gamma and Hsp90 complex in human colonic epithelial cells
    Kyeong Ah Park
    Department of Pharmacology, Cancer Research Institute, College of Medicine, Chungnam National University, 6 Munhwa dong, Jung Gu, Daejeon 301 131, Korea
    Carcinogenesis 28:71-80. 2007
    ....