Tae Hyun Paik

Summary

Affiliation: College of Medicine
Country: Korea

Publications

  1. doi request reprint Mycobacterial cell-wall skeleton as a universal vaccine vehicle for antigen conjugation
    Tae Hyun Paik
    Department of Microbiology, College of Medicine, Chungnam National University, Daejeon 301 747, South Korea
    Vaccine 28:7873-80. 2010
  2. ncbi request reprint Intracellular network of phosphatidylinositol 3-kinase, mammalian target of the rapamycin/70 kDa ribosomal S6 kinase 1, and mitogen-activated protein kinases pathways for regulating mycobacteria-induced IL-23 expression in human macrophages
    Chul Su Yang
    Department of Microbiology, College of Medicine, Chungnam National University, Daejeon 301 747, South Korea
    Cell Microbiol 8:1158-71. 2006
  3. ncbi request reprint Role of the phosphatidylinositol 3-kinase and mitogen-activated protein kinase pathways in the secretion of tumor necrosis factor-alpha and interleukin-10 by the PPD antigen of Mycobacterium tuberculosis
    Saet Byel Jung
    Department of Microbiology, College of Medicine, Chungnam National University, Daejeon, South Korea
    J Clin Immunol 25:482-90. 2005
  4. ncbi request reprint Role of mitogen-activated protein kinase pathways in the production of tumor necrosis factor-alpha, interleukin-10, and monocyte chemotactic protein-1 by Mycobacterium tuberculosis H37Rv-infected human monocytes
    Chang Hwa Song
    Department of Microbiology, College of Medicine, Chungnam National University, 6 Munhwa dong, Jung ku, Daejeon 301 747, Korea
    J Clin Immunol 23:194-201. 2003
  5. ncbi request reprint Depressed interleukin-12 production by peripheral blood mononuclear cells after in vitro stimulation with the 30-kDa antigen in recurrent pulmonary tuberculosis patients
    Ji Sook Lee
    Department of Microbiology, College of Medicine, Chungnam National University, 6 Munhwa dong, Jung ku, Taejon 301 747, Republic of Korea
    Med Microbiol Immunol 192:61-9. 2003
  6. ncbi request reprint Identification of the new T-cell-stimulating antigens from Mycobacterium tuberculosis culture filtrate
    Jae Hyun Lim
    Department of Microbiology, College of Medicine, Chungnam National University, 6 Munhwa dong, Jung ku, Daejeon 301 747, South Korea
    FEMS Microbiol Lett 232:51-9. 2004
  7. pmc The mycobacterial 38-kilodalton glycolipoprotein antigen activates the mitogen-activated protein kinase pathway and release of proinflammatory cytokines through Toll-like receptors 2 and 4 in human monocytes
    Saet Byel Jung
    Department of Microbiology, College of Medicine, Chungnam National University, 6 Munhwa dong, Jungku, Daejeon 301 747, South Korea
    Infect Immun 74:2686-96. 2006
  8. pmc Interleukin-8 is differentially expressed by human-derived monocytic cell line U937 infected with Mycobacterium tuberculosis H37Rv and Mycobacterium marinum
    Chang Hwa Song
    Department of Microbiology, College of Medicine, Chungnam National University, 6 Mun hwa dong, Jung ku, Daejeon 301 747, Republic of Korea
    Infect Immun 71:5480-7. 2003
  9. ncbi request reprint Protein kinase C zeta plays an essential role for Mycobacterium tuberculosis-induced extracellular signal-regulated kinase 1/2 activation in monocytes/macrophages via Toll-like receptor 2
    Chul Su Yang
    Department of Microbiology, College of Medicine, Chungnam National University, Daejeon 301 747, Seoul, Korea
    Cell Microbiol 9:382-96. 2007
  10. pmc Mycobacterium tuberculosis HBHA protein reacts strongly with the serum immunoglobulin M of tuberculosis patients
    A Rum Shin
    Department of Microbiology, College of Medicine, Chungnam National University, 6 Muwha Dong, Jung ku, Daejeon 301 747, Korea
    Clin Vaccine Immunol 13:869-75. 2006

Collaborators

  • Eun Kyeong Jo
  • Chul Su Yang
  • Saet Byel Jung
  • Kyu Lim
  • Sakae Tanaka
  • Ji Sook Lee
  • Chang Hwa Song
  • Jeong Kyu Park
  • Hwa Jung Kim
  • Jae Hyun Lim
  • Jae Min Yuk
  • Dong Min Shin
  • Hye Mi Lee
  • A Rum Shin
  • Kil Soo Lee
  • Su Young Kim
  • Jun Sang Kim
  • Ki Hye Kim
  • Kyoung Sub Song
  • Sang Hee Lee
  • Jin Man Kim
  • Kwang Kyu Kim
  • Mal Hyun Shon
  • Chul Hee Kim
  • Ji Won Suhr
  • So Hyun Lee
  • Suck Jun Kong

Detail Information

Publications12

  1. doi request reprint Mycobacterial cell-wall skeleton as a universal vaccine vehicle for antigen conjugation
    Tae Hyun Paik
    Department of Microbiology, College of Medicine, Chungnam National University, Daejeon 301 747, South Korea
    Vaccine 28:7873-80. 2010
    ....
  2. ncbi request reprint Intracellular network of phosphatidylinositol 3-kinase, mammalian target of the rapamycin/70 kDa ribosomal S6 kinase 1, and mitogen-activated protein kinases pathways for regulating mycobacteria-induced IL-23 expression in human macrophages
    Chul Su Yang
    Department of Microbiology, College of Medicine, Chungnam National University, Daejeon 301 747, South Korea
    Cell Microbiol 8:1158-71. 2006
    ....
  3. ncbi request reprint Role of the phosphatidylinositol 3-kinase and mitogen-activated protein kinase pathways in the secretion of tumor necrosis factor-alpha and interleukin-10 by the PPD antigen of Mycobacterium tuberculosis
    Saet Byel Jung
    Department of Microbiology, College of Medicine, Chungnam National University, Daejeon, South Korea
    J Clin Immunol 25:482-90. 2005
    ..Collectively, these data suggest that the PI 3-K and MAPK pathways play a central role in the regulation of both pro- and anti-inflammatory cytokines by the PPD antigen of M. tuberculosis...
  4. ncbi request reprint Role of mitogen-activated protein kinase pathways in the production of tumor necrosis factor-alpha, interleukin-10, and monocyte chemotactic protein-1 by Mycobacterium tuberculosis H37Rv-infected human monocytes
    Chang Hwa Song
    Department of Microbiology, College of Medicine, Chungnam National University, 6 Munhwa dong, Jung ku, Daejeon 301 747, Korea
    J Clin Immunol 23:194-201. 2003
    ..Collectively, these results suggest that induction of the MAPK pathway is required for the expression of TNF-alpha, IL-10, and MCP-1 by human monocytes during M. tuberculosis H37Rv infection...
  5. ncbi request reprint Depressed interleukin-12 production by peripheral blood mononuclear cells after in vitro stimulation with the 30-kDa antigen in recurrent pulmonary tuberculosis patients
    Ji Sook Lee
    Department of Microbiology, College of Medicine, Chungnam National University, 6 Munhwa dong, Jung ku, Taejon 301 747, Republic of Korea
    Med Microbiol Immunol 192:61-9. 2003
    ....
  6. ncbi request reprint Identification of the new T-cell-stimulating antigens from Mycobacterium tuberculosis culture filtrate
    Jae Hyun Lim
    Department of Microbiology, College of Medicine, Chungnam National University, 6 Munhwa dong, Jung ku, Daejeon 301 747, South Korea
    FEMS Microbiol Lett 232:51-9. 2004
    ..These results suggest that MTSP11 antigen should be further evaluated as a component of a subunit vaccine...
  7. pmc The mycobacterial 38-kilodalton glycolipoprotein antigen activates the mitogen-activated protein kinase pathway and release of proinflammatory cytokines through Toll-like receptors 2 and 4 in human monocytes
    Saet Byel Jung
    Department of Microbiology, College of Medicine, Chungnam National University, 6 Munhwa dong, Jungku, Daejeon 301 747, South Korea
    Infect Immun 74:2686-96. 2006
    ....
  8. pmc Interleukin-8 is differentially expressed by human-derived monocytic cell line U937 infected with Mycobacterium tuberculosis H37Rv and Mycobacterium marinum
    Chang Hwa Song
    Department of Microbiology, College of Medicine, Chungnam National University, 6 Mun hwa dong, Jung ku, Daejeon 301 747, Republic of Korea
    Infect Immun 71:5480-7. 2003
    ..Additionally, our data indicate that differential signal transduction pathways may underlie the distinct patterns of IL-8 secretion in cells infected by the two mycobacteria...
  9. ncbi request reprint Protein kinase C zeta plays an essential role for Mycobacterium tuberculosis-induced extracellular signal-regulated kinase 1/2 activation in monocytes/macrophages via Toll-like receptor 2
    Chul Su Yang
    Department of Microbiology, College of Medicine, Chungnam National University, Daejeon 301 747, Seoul, Korea
    Cell Microbiol 9:382-96. 2007
    ..This is the first demonstration that PKCzeta interacts with TLR2 to play an essential role in MTB-induced ERK 1/2 activation and subsequent TNF-alpha expression in monocytes/macrophages...
  10. pmc Mycobacterium tuberculosis HBHA protein reacts strongly with the serum immunoglobulin M of tuberculosis patients
    A Rum Shin
    Department of Microbiology, College of Medicine, Chungnam National University, 6 Muwha Dong, Jung ku, Daejeon 301 747, Korea
    Clin Vaccine Immunol 13:869-75. 2006
    ..tuberculosis into epithelial cells. These findings suggest that IgM antibody to HBHA may play a role in protection against extrapulmonary dissemination...
  11. ncbi request reprint Bacillus calmette-guerin cell wall cytoskeleton enhances colon cancer radiosensitivity through autophagy
    Jae Min Yuk
    Department of Microbiology, College of Medicine, Chungnam National University, Daejeon, Korea
    Autophagy 6:46-60. 2010
    ..Our data suggest that BCG/CWS in combination with IR is a promising therapeutic strategy for enhancing radiation therapy in colon cancer cells through the induction of autophagy...
  12. doi request reprint Roles of reactive oxygen species in CXCL8 and CCL2 expression in response to the 30-kDa antigen of Mycobacterium tuberculosis
    Hye Mi Lee
    Department of Microbiology, College of Medicine, Chungnam National University, 6 Munhwa dong, Jung ku, Daejeon, 301 747, South Korea
    J Clin Immunol 29:46-56. 2009
    ..tuberculosis) is a strong inducer of innate and adaptive immune responses in human tuberculosis. The generation of reactive oxygen species (ROS) plays an important role in inflammatory signaling as well as antimicrobial defense...