H I Yun

Summary

Affiliation: Chungnam National University
Country: Korea

Publications

  1. pmc In vivo metabolism of Talosin A, new isoflavonol glycoside from Kitasatospora kifunensis, in rats
    Jong Hwan Lim
    B and C Biopharm, Advanced Institutes of Convergence Technology, Suwon 443 270, Korea
    J Vet Sci 12:115-9. 2011
  2. doi request reprint Altered pharmacokinetics of enrofloxacin in experimental models of hepatic and renal impairment
    Y H Hwang
    Department of Veterinary Pharmacology and Toxicology, College of Veterinary Medicine, Chungnam National University, Yuseong Gu, Daejeon 305 764, Republic of Korea
    Vet Res Commun 33:481-7. 2009
  3. ncbi request reprint Pharmacokinetics of enrofloxacin in Korean catfish (Silurus asotus)
    M S Kim
    Division of Veterinary Pharmacology and Toxicology, College of Veterinary Medicine, Chungnam National University, Daejeon, Korea
    J Vet Pharmacol Ther 29:397-402. 2006
  4. ncbi request reprint Peri- and postnatal developmental toxicity of the fluoroquinolone antibacterial DW-116 in rats
    J C Kim
    College of Veterinary Medicine, Chonnam National University, Gwangju 500 757, Republic of Korea
    Food Chem Toxicol 42:389-95. 2004
  5. ncbi request reprint Pharmacokinetics of florfenicol and its metabolite, florfenicol amine, in the Korean catfish (Silurus asotus)
    B K Park
    Division of Veterinary Pharmacology and Toxicology, College of Veterinary Medicine, Chungnam National University, Daejeon, Republic of Korea
    J Vet Pharmacol Ther 29:37-40. 2006
  6. ncbi request reprint Pharmacokinetics of florfenicol and its major metabolite, florfenicol amine, in rabbits
    B K Park
    Division of Veterinary Pharmacology and Toxicology, College of Veterinary Medicine, Chungnam National University, Daejeon, Korea
    J Vet Pharmacol Ther 30:32-6. 2007
  7. ncbi request reprint Pharmacokinetic/pharmacodynamic modelling of roxithromycin for the inhibitory effect of tumour necrosis factor-alpha and interleukin-6 production in dogs
    J H Lim
    College of Veterinary Medicine, Chungnam National University, 220 Gung Dong, Yuseong Gu, Daejeon, Korea
    J Vet Med A Physiol Pathol Clin Med 53:394-8. 2006
  8. ncbi request reprint Clinical pharmacokinetics of norfloxacin-glycine acetate after intravenous and intramuscular administration to horses
    S C Park
    Veterinary Pharmacology and Toxicology Labs, College of Veterinary Medicine, Kyungpook National University, 702 701 Sangyeok dong, Buk Gu, Daegu, Republic of Korea
    Res Vet Sci 74:79-83. 2003
  9. ncbi request reprint Developmental toxicity assessment of the new fluoroquinolone antibacterial DW-116 in rabbits
    J C Kim
    College of Veterinary Medicine, Chonnam National University, Gwangju 500 757, Republic of Korea
    J Appl Toxicol 25:52-9. 2005

Collaborators

Detail Information

Publications10

  1. pmc In vivo metabolism of Talosin A, new isoflavonol glycoside from Kitasatospora kifunensis, in rats
    Jong Hwan Lim
    B and C Biopharm, Advanced Institutes of Convergence Technology, Suwon 443 270, Korea
    J Vet Sci 12:115-9. 2011
    ..GT-Tal was metabolized into its corresponding conjugates or underwent deglycosylation to form GT, whereas GT-Glu was metabolized into its aglycone, GT...
  2. doi request reprint Altered pharmacokinetics of enrofloxacin in experimental models of hepatic and renal impairment
    Y H Hwang
    Department of Veterinary Pharmacology and Toxicology, College of Veterinary Medicine, Chungnam National University, Yuseong Gu, Daejeon 305 764, Republic of Korea
    Vet Res Commun 33:481-7. 2009
    ..05) by renal impairment. In conclusion, these results suggested that renal impairment could affect the pharmacokinetics of enrofloxacin...
  3. ncbi request reprint Pharmacokinetics of enrofloxacin in Korean catfish (Silurus asotus)
    M S Kim
    Division of Veterinary Pharmacology and Toxicology, College of Veterinary Medicine, Chungnam National University, Daejeon, Korea
    J Vet Pharmacol Ther 29:397-402. 2006
    ..25 h, with the C(max) of 0.03 +/- 0.01 microg/mL at 6.67 +/- 2.31 h. Ciprofloxacin was eliminated with terminal half-life t(1/2,beta) of 52.08 +/- 17.34 h for intravenous administration and 52.43 +/- 22.37 h for oral administration...
  4. ncbi request reprint Peri- and postnatal developmental toxicity of the fluoroquinolone antibacterial DW-116 in rats
    J C Kim
    College of Veterinary Medicine, Chonnam National University, Gwangju 500 757, Republic of Korea
    Food Chem Toxicol 42:389-95. 2004
    ..e., 250 mg/kg/day. Under the experimental conditions, the no-observed-adverse-effect level for peri- and postnatal developmental toxicity was considered to be 50 mg/kg/day...
  5. ncbi request reprint Pharmacokinetics of florfenicol and its metabolite, florfenicol amine, in the Korean catfish (Silurus asotus)
    B K Park
    Division of Veterinary Pharmacology and Toxicology, College of Veterinary Medicine, Chungnam National University, Daejeon, Republic of Korea
    J Vet Pharmacol Ther 29:37-40. 2006
    ..91 +/- 0.69 and 3.57 +/- 0.65 mg/L) were reached at 0.5 and 7.33 +/- 1.15 h. The mean metabolic rate of florfenicol amine after i.v. and p.o. administration was 0.4 and 0.5 respectively...
  6. ncbi request reprint Pharmacokinetics of florfenicol and its major metabolite, florfenicol amine, in rabbits
    B K Park
    Division of Veterinary Pharmacology and Toxicology, College of Veterinary Medicine, Chungnam National University, Daejeon, Korea
    J Vet Pharmacol Ther 30:32-6. 2007
    ..38 +/- 0.97 microg/mL) were reached at 0.88 +/- 0.78 and 2.10 +/- 1.08 h respectively. Florfenicol amine was eliminated with an elimination half-life of 1.84 +/- 0.17 and 2.35 +/- 0.94 h after i.v. and p.o. administration respectively...
  7. ncbi request reprint Pharmacokinetic/pharmacodynamic modelling of roxithromycin for the inhibitory effect of tumour necrosis factor-alpha and interleukin-6 production in dogs
    J H Lim
    College of Veterinary Medicine, Chungnam National University, 220 Gung Dong, Yuseong Gu, Daejeon, Korea
    J Vet Med A Physiol Pathol Clin Med 53:394-8. 2006
    ..04 microg/h; EC(50) = 21.07 mg/l) production, respectively. The inhibitory effect of roxithromycin on production can be adequately described by the indirect response model with an E(max) concentration-effect relationship...
  8. ncbi request reprint Clinical pharmacokinetics of norfloxacin-glycine acetate after intravenous and intramuscular administration to horses
    S C Park
    Veterinary Pharmacology and Toxicology Labs, College of Veterinary Medicine, Kyungpook National University, 702 701 Sangyeok dong, Buk Gu, Daegu, Republic of Korea
    Res Vet Sci 74:79-83. 2003
    ..36 and 7.35 mgkg(-1) for i.m. and i.v. administration, respectively...
  9. ncbi request reprint Developmental toxicity assessment of the new fluoroquinolone antibacterial DW-116 in rabbits
    J C Kim
    College of Veterinary Medicine, Chonnam National University, Gwangju 500 757, Republic of Korea
    J Appl Toxicol 25:52-9. 2005
    ..The no-observed-adverse-effect levels (NOAELs) of DW-116 are considered to be 19.5 mg kg(-1) day(-1) for does and embryo-foetuses, respectively...