Wan Hee Yoon

Summary

Affiliation: Chungnam National University
Country: Korea

Publications

  1. doi request reprint The tumorigenic, invasive and metastatic potential of epithelial and round subpopulations of the SW480 human colon cancer cell line
    Wan Hee Yoon
    Department of Surgery, Chungnam National University College of Medicine, Daejeon 301 747, Korea
    Mol Med Rep 1:763-8. 2008
  2. ncbi request reprint Differential regulation of vimentin mRNA by 12-O-tetradecanoylphorbol 13-acetate and all-trans-retinoic acid correlates with motility of Hep 3B human hepatocellular carcinoma cells
    Wan Hee Yoon
    Department of Surgery, College of Medicine, Cancer Research Institute, Chungnam National University and Hospital, 640 Daesa dong, Joong ku, 301 721 Daejon, South Korea
    Cancer Lett 203:99-105. 2004
  3. ncbi request reprint Gabexate mesilate inhibits colon cancer growth, invasion, and metastasis by reducing matrix metalloproteinases and angiogenesis
    Wan Hee Yoon
    Department of Surgery, Cancer Research Institute, Chungnam National University College of Medicine, Daejon, Korea
    Clin Cancer Res 10:4517-26. 2004
  4. ncbi request reprint Transcriptional repression of vimentin gene expression by pyrroline dithiocarbamate during 12-O-tetradecanoylphorbol-13-acetate-dependent differentiation of HL-60 cells
    Meizi Zheng
    Department of Biochemistry, College of Medicine, Chungnam National University, Daejeon 301 747, Korea
    Oncol Rep 14:713-7. 2005
  5. pmc Activity and expression of urokinase-type plasminogen activator and matrix metalloproteinases in human colorectal cancer
    Tae Dong Kim
    Department of Surgery, College of Medicine, Chungnam National University and Hospital, Daejeon, 301 721, Korea
    BMC Cancer 6:211. 2006
  6. pmc Protein-bound polysaccharide from Phellinus linteus inhibits tumor growth, invasion, and angiogenesis and alters Wnt/β-catenin in SW480 human colon cancer cells
    Kyoung Sub Song
    Department of Biochemistry, College of Medicine, Chungnam National University, Joong Gu, Daejeon, Korea
    BMC Cancer 11:307. 2011
  7. doi request reprint Radiation-induced thymidine phosphorylase upregulation in rectal cancer is mediated by tumor-associated macrophages by monocyte chemoattractant protein-1 from cancer cells
    Tae Dong Kim
    Department of Biochemistry, Chungnam National University College of Medicine, Daejon, Korea
    Int J Radiat Oncol Biol Phys 73:853-60. 2009
  8. ncbi request reprint Protein-bound polysaccharide from Phellinus linteus induces G2/M phase arrest and apoptosis in SW480 human colon cancer cells
    Ge Li
    Department of Surgery, College of Medicine, Cancer Research Institute, Chungnam National University and Hospital, 640 Daesa dong, Joong ku, Daejon 301 721, South Korea
    Cancer Lett 216:175-81. 2004
  9. pmc PMA synergistically enhances apicularen A-induced cytotoxicity by disrupting microtubule networks in HeLa cells
    Kang Sik Seo
    Department of Biochemistry, College of Medicine, Chungnam National University, Daejeon, Korea
    BMC Cancer 14:36. 2014
  10. doi request reprint Omega-3-polyunsaturated fatty acids suppress pancreatic cancer cell growth in vitro and in vivo via downregulation of Wnt/Beta-catenin signaling
    Kyoung Sub Song
    Department of Biochemistry, College of Medicine, Chungnam National University, Daejeon, Korea
    Pancreatology 11:574-84. 2011

Collaborators

  • Kyu Lim
  • Tae-Dong Kim
  • Tong Wu
  • Gang Min Hur
  • Jin-Man Kim
  • Sun Hoe Koo
  • Longzhen Piao
  • Jongsun Park
  • Young Rae Kim
  • Chang Han
  • Ki Hwan Kim
  • Eun Kyeong Jo
  • Kyoung Sub Song
  • Byung Doo Hwang
  • Kang Sik Seo
  • Kaipeng Jing
  • Gi Ryang Kweon
  • Jun Young Heo
  • Ge Li
  • Eun Jin Yun
  • Seung Kiel Park
  • Soyeon Shin
  • Mee Young Son
  • Yeon Joo Jung
  • Chae Ok Yun
  • Hae Duck Park
  • Kyeong Ah Park
  • Shengjin Li
  • Dong Goo Bae
  • Meizi Zheng
  • Hee Jin Chang
  • Ung Chae Park
  • Chung Park
  • Chi Bom Chae
  • Yong Song Gho
  • Kwang Sun Suh
  • Jeongsu Han
  • Jing X Kang
  • Soyeon Jeong
  • Seung Bo Seo
  • Jae Kuk Yoo
  • Nayeong Kim
  • Hye Rim Oh
  • Deog Yeon Jo
  • Byeong Hwa Jeon
  • Heung Sun Kwon
  • Seong Keun Kim
  • Yoon A Kang
  • Hyun Chul Shin
  • Hee Sun Byun
  • Eunsung Junn
  • Keum Jin Yang
  • Sanghee Shin
  • Minho Won
  • Jeong Ho Seok
  • Seung Gu Yeo
  • Moon June Cho
  • Kyu Sang Song
  • Kyung Hae Jung
  • Dae Hyun Kim
  • Il Jin Kim
  • Seung Yong Jeong
  • Dae Yong Kim
  • Byong Chul Yoo
  • Dae Kyung Sohn
  • Seok Byung Lim
  • Joong Bae Ahn
  • Hyo Seong Choi
  • Min Kyun Na
  • Moo Kyung Seong
  • Hong Kyu Baik
  • Dong Hee Kim
  • Hwan Chul Kim
  • Chang Sik Yu
  • Soon Sup Chung
  • Byoung Jeon Park
  • Nam Doo Hong
  • Kwang In Kweon
  • Zaesung No
  • Young Chul Lee
  • Jong Woong Ahn

Detail Information

Publications26

  1. doi request reprint The tumorigenic, invasive and metastatic potential of epithelial and round subpopulations of the SW480 human colon cancer cell line
    Wan Hee Yoon
    Department of Surgery, Chungnam National University College of Medicine, Daejeon 301 747, Korea
    Mol Med Rep 1:763-8. 2008
    ..These findings suggest that E- and R-type cells may have different biological properties in terms of colon cancer progression, regression, invasion and nodal metastasis, and might serve as a useful model for these studies...
  2. ncbi request reprint Differential regulation of vimentin mRNA by 12-O-tetradecanoylphorbol 13-acetate and all-trans-retinoic acid correlates with motility of Hep 3B human hepatocellular carcinoma cells
    Wan Hee Yoon
    Department of Surgery, College of Medicine, Cancer Research Institute, Chungnam National University and Hospital, 640 Daesa dong, Joong ku, 301 721 Daejon, South Korea
    Cancer Lett 203:99-105. 2004
    ..These findings suggest that TPA and RA could modulate the invasive potential of Hep 3B cells by altering cellular motility related to differential regulation of vimentin mRNA...
  3. ncbi request reprint Gabexate mesilate inhibits colon cancer growth, invasion, and metastasis by reducing matrix metalloproteinases and angiogenesis
    Wan Hee Yoon
    Department of Surgery, Cancer Research Institute, Chungnam National University College of Medicine, Daejon, Korea
    Clin Cancer Res 10:4517-26. 2004
    ..These results suggest that GM is a novel inhibitor of MMPs and that it may inhibit the invasion and metastasis of human colon cancer cells by blocking MMPs and neoangiogenesis...
  4. ncbi request reprint Transcriptional repression of vimentin gene expression by pyrroline dithiocarbamate during 12-O-tetradecanoylphorbol-13-acetate-dependent differentiation of HL-60 cells
    Meizi Zheng
    Department of Biochemistry, College of Medicine, Chungnam National University, Daejeon 301 747, Korea
    Oncol Rep 14:713-7. 2005
    ..Taken together, these results suggest that NF-kappaB may be an essential transacting factor for transcriptional repression of the vimentin gene by PDTC during TPA-dependent differentiation of HL-60 cells...
  5. pmc Activity and expression of urokinase-type plasminogen activator and matrix metalloproteinases in human colorectal cancer
    Tae Dong Kim
    Department of Surgery, College of Medicine, Chungnam National University and Hospital, Daejeon, 301 721, Korea
    BMC Cancer 6:211. 2006
    ..We designed this study to determine any differences in the expression of MMP-2, MMP-9 and uPA system between colon and rectal cancer tissues...
  6. pmc Protein-bound polysaccharide from Phellinus linteus inhibits tumor growth, invasion, and angiogenesis and alters Wnt/β-catenin in SW480 human colon cancer cells
    Kyoung Sub Song
    Department of Biochemistry, College of Medicine, Chungnam National University, Joong Gu, Daejeon, Korea
    BMC Cancer 11:307. 2011
    ..However, the molecular mechanisms responsible for the anti-tumor properties of PL remain to be explored. Experiments were carried out to unravel the anticancer effects of PL...
  7. doi request reprint Radiation-induced thymidine phosphorylase upregulation in rectal cancer is mediated by tumor-associated macrophages by monocyte chemoattractant protein-1 from cancer cells
    Tae Dong Kim
    Department of Biochemistry, Chungnam National University College of Medicine, Daejon, Korea
    Int J Radiat Oncol Biol Phys 73:853-60. 2009
    ..The mechanisms of thymidine phosphorylase (TP) regulation induced by radiation therapy (XRT) in various tumors are poorly understood. We investigated the effect and mechanisms of preoperative XRT on TP expression in rectal cancer tissues...
  8. ncbi request reprint Protein-bound polysaccharide from Phellinus linteus induces G2/M phase arrest and apoptosis in SW480 human colon cancer cells
    Ge Li
    Department of Surgery, College of Medicine, Cancer Research Institute, Chungnam National University and Hospital, 640 Daesa dong, Joong ku, Daejon 301 721, South Korea
    Cancer Lett 216:175-81. 2004
    ..These results suggest that PL has a direct antitumor effect through apoptosis and cell cycle blockade in certain cancer cells...
  9. pmc PMA synergistically enhances apicularen A-induced cytotoxicity by disrupting microtubule networks in HeLa cells
    Kang Sik Seo
    Department of Biochemistry, College of Medicine, Chungnam National University, Daejeon, Korea
    BMC Cancer 14:36. 2014
    ..Apicularen A induces cytotoxicity in tumor cells through disrupting microtubule networks by tubulin down-regulation. In this study, we examined whether PMA increases apicularen A-induced cytotoxicity in HeLa cells...
  10. doi request reprint Omega-3-polyunsaturated fatty acids suppress pancreatic cancer cell growth in vitro and in vivo via downregulation of Wnt/Beta-catenin signaling
    Kyoung Sub Song
    Department of Biochemistry, College of Medicine, Chungnam National University, Daejeon, Korea
    Pancreatology 11:574-84. 2011
    ..However, the relationship between ω3-PUFAs and β-catenin, one of the key components of the Wnt signaling pathway, in human pancreatic cancer remains poorly characterized...
  11. ncbi request reprint ATF is important to late S phase-dependent regulation of DNA topoisomerase IIalpha gene expression in HeLa cells
    Mee Young Son
    Department of Biochemistry, Chungnam National University, Moonhwa dong, Jungu, Daejeon 301 747, South Korea
    Cancer Lett 184:81-8. 2002
    ..Taken together, these results suggest that ATF may be essential transacting factor for maximal expression of Topo IIalpha gene during late S phase in HeLa cells...
  12. ncbi request reprint Phosphorylation of octamer-binding transcriptional factor may be correlated with H2B histone gene repression during 12-O-tetradecanoylphorbol 13-acetate-dependent differentiation of HL-60 cells
    Kyu Lim
    Department of Biochemistry, College of Medicine, Chungnam National University, Jungu, Daejeon 301 747, Korea
    Oncol Rep 14:727-31. 2005
    ....
  13. pmc Comparison of the efficacy of oral capecitabine versus bolus 5-FU in preoperative radiotherapy of locally advanced rectal cancer
    Jae Sung Kim
    Department of Radiation Oncology, College of Medicine, Seoul National University, Seoul, Korea
    J Korean Med Sci 21:52-7. 2006
    ..Preoperative chemoradiation using oral capecitabine was better tolerated than bolus 5-FU and was more effective in the promotion of both down-staging and sphincter preservation in patients with LARC...
  14. ncbi request reprint Preoperative chemoradiation using oral capecitabine in locally advanced rectal cancer
    Jun Sang Kim
    Department of Therapeutic Radiology, College of Medicine, Chungnam National University, Jung Gu, Taejon, South Korea
    Int J Radiat Oncol Biol Phys 54:403-8. 2002
    ..We attempted to evaluate the efficacy and toxicity of preoperative chemoradiation using capecitabine in locally advanced rectal cancer...
  15. pmc Docosahexaenoic acid induces autophagy through p53/AMPK/mTOR signaling and promotes apoptosis in human cancer cells harboring wild-type p53
    Kaipeng Jing
    Department of Biochemistry, College of Medicine, Chungnam National University, Daejeon, Korea
    Autophagy 7:1348-58. 2011
    ..Overall, our results demonstrate that autophagy contributes to the cytotoxicity of DHA in cancer cells harboring wild-type p53...
  16. ncbi request reprint Epidermal growth factor receptor as a predictor of tumor downstaging in locally advanced rectal cancer patients treated with preoperative chemoradiotherapy
    Jun Sang Kim
    Department of Radiation Oncology, Chungnam National University College of Medicine, Daejeon, Republic of Korea
    Int J Radiat Oncol Biol Phys 66:195-200. 2006
    ..To examine retrospectively whether levels of epidermal growth factor receptor (EGFR) expression can predict tumor downstaging after preoperative chemoradiotherapy in patients with locally advanced rectal cancer...
  17. doi request reprint Downregulation of APE1/Ref-1 is involved in the senescence of mesenchymal stem cells
    Jun Young Heo
    Department of Biochemistry, College of Medicine, Chungnam National University, Teajeon, South Korea
    Stem Cells 27:1455-62. 2009
    ..Maintaining characteristics of hBMSCs by regulating intracellular reactive oxygen species production can contribute to tissue regeneration and to improved cell therapy...
  18. ncbi request reprint Sustained activation of protein kinase C downregulates nuclear factor-kappaB signaling by dissociation of IKK-gamma and Hsp90 complex in human colonic epithelial cells
    Kyeong Ah Park
    Department of Pharmacology, Cancer Research Institute, College of Medicine, Chungnam National University, 6 Munhwa dong, Jung Gu, Daejeon 301 131, Korea
    Carcinogenesis 28:71-80. 2007
    ....
  19. ncbi request reprint Single-stage procedure with intraoperative colonoscopy and colonic irrigation in patients with obstructing left-sided colonic cancer
    Ung Chae Park
    Department of Surgery, College of Medicine, Kon Kuk University, Chungju, Korea
    Int J Colorectal Dis 19:487-92. 2004
    ..This study evaluated the efficacy of a newly developed device for performing a single-stage procedure in patients with obstructing left-sided colon cancer...
  20. pmc Transduction of artificial transcriptional regulatory proteins into human cells
    Chae Ok Yun
    Brain Korea 21 Project for Medical Sciences, Institute for Cancer Research, Yonsei Cancer Center, Yonsei University College of Medicine, Seoul, South Korea
    Nucleic Acids Res 36:e103. 2008
    ..The PTD-attached ZF-TF was delivered efficiently into human cells in vitro. In addition, the VEGF-A-specific transcriptional repressor retarded the growth rate of tumor cells in a mouse xenograft experiment...
  21. ncbi request reprint Apicularen A induces cell death through Fas ligand up-regulation and microtubule disruption by tubulin down-regulation in HM7 human colon cancer cells
    Jong Seok Kim
    Department of Biochemistry, College of Medicine, Chungnam National University, Daejeon, Republic of Korea
    Clin Cancer Res 13:6509-17. 2007
    ..In this study, we investigated the molecular mechanisms of apicularen A-induced cell death in HM7 human colon cancer cells in vitro and anticancer activity in vivo...
  22. ncbi request reprint Epidermal growth factor receptor as a prognostic factor in locally advanced rectal-cancer patients treated with preoperative chemoradiation
    Shengjin Li
    Department of Pathology, College of Medicine, Chungnam National University, Daejeon, Republic of Korea
    Int J Radiat Oncol Biol Phys 65:705-12. 2006
    ..We investigated the prognostic value of epidermal growth factor receptor (EGFR) expression in pretreatment biopsy specimens from patients with locally advanced rectal cancer treated with preoperative chemoradiation...
  23. ncbi request reprint Bax, a predictive marker for therapeutic response to preoperative chemoradiotherapy in patients with rectal carcinoma
    Hee Jin Chang
    Research Institute and Hospital, National Cancer Center, Gyeonggi 411 764, Korea
    Hum Pathol 36:364-71. 2005
    ..017). This result confirms that apoptosis plays an important role in tumor response to CRT and provides evidence that Bax may serve as a predictable molecular marker for chemoradiosensitivity in rectal carcinoma...
  24. ncbi request reprint Anti-flt1 peptide, a vascular endothelial growth factor receptor 1-specific hexapeptide, inhibits tumor growth and metastasis
    Dong Goo Bae
    Department of Life Science, Division of Molecular and Life Sciences, Postech Biotech Center, Pohang University of Science and Technology, Pohang, Korea
    Clin Cancer Res 11:2651-61. 2005
    ....
  25. ncbi request reprint Antiplasmin activity of a peptide that binds to the receptor-binding site of angiogenin
    Yong Song Gho
    Department of Life Science, Division of Molecular and Life Sciences, Pohang University of Science and Technology, Pohang 790 784, Korea
    J Biol Chem 277:9690-4. 2002
    ..Therefore, the 11-amino acid peptide chANG has both antiangiogenin and antiplasmin activity, and could be useful in the development of anticancer agents...
  26. ncbi request reprint Rottlerin induces autophagy and apoptotic cell death through a PKC-delta-independent pathway in HT1080 human fibrosarcoma cells: the protective role of autophagy in apoptosis
    Kyoung Sub Song
    Department of Biochemistry, Chungnam National University, Munhwa dong, Joong Gu, Daejeon, Korea
    Autophagy 4:650-8. 2008
    ....