Kyu Lim

Summary

Affiliation: Chungnam National University
Country: Korea

Publications

  1. Seo K, Kim J, Park J, Song K, Yun E, Park J, et al. PMA synergistically enhances apicularen A-induced cytotoxicity by disrupting microtubule networks in HeLa cells. BMC Cancer. 2014;14:36 pubmed publisher
    ..These results suggest that the synergy between PMA and apicularen A is involved by PKC? activation and microtubule disruption, and that may inform the development of novel approaches to treat cancer. ..
  2. Jeong S, Jing K, Kim N, Shin S, Kim S, Song K, et al. Docosahexaenoic acid-induced apoptosis is mediated by activation of mitogen-activated protein kinases in human cancer cells. BMC Cancer. 2014;14:481 pubmed publisher
    ..Together, these results indicate that DHA-induced MAPKs activation is dependent on its capacity to provoke mitochondrial ROS generation, and accounts for its cytotoxic effect in human cancer cells. ..
  3. Song K, Li G, Kim J, Jing K, Kim T, Kim J, et al. Protein-bound polysaccharide from Phellinus linteus inhibits tumor growth, invasion, and angiogenesis and alters Wnt/?-catenin in SW480 human colon cancer cells. BMC Cancer. 2011;11:307 pubmed publisher
    ..These data suggest that PL suppresses tumor growth, invasion, and angiogenesis through the inhibition of Wnt/?-catenin signaling in certain colon cancer cells. ..
  4. Lim K, Han C, Dai Y, Shen M, Wu T. Omega-3 polyunsaturated fatty acids inhibit hepatocellular carcinoma cell growth through blocking beta-catenin and cyclooxygenase-2. Mol Cancer Ther. 2009;8:3046-55 pubmed publisher
    ..These findings provide important preclinical evidence and molecular insight for utilization of omega-3 PUFAs for the chemoprevention and treatment of human HCC. ..
  5. Park H, Son W, Chae D, Lee J, Kim I, Yang W, et al. Cell cloning-on-the-spot by using an attachable silicone cylinder. Biochem Biophys Res Commun. 2016;474:768-772 pubmed publisher
    ..We tested the silicone cylinder in the monoclonal subcloning from a heterogeneous population of a breast cancer cell line, MDA-MB-231, and readily established independent MDA-MB-231 subclones showing different sublineage phenotypes. ..
  6. Gwon D, Hwang T, Ro J, Kang Y, Jeong J, Kim D, et al. High Endogenous Accumulation of ?-3 Polyunsaturated Fatty Acids Protect against Ischemia-Reperfusion Renal Injury through AMPK-Mediated Autophagy in Fat-1 Mice. Int J Mol Sci. 2017;18: pubmed publisher
    ..Collectively, ?3-PUFAs in fat-1 mice contributed to AMPK mediated autophagy activation, leading to a renoprotective response...

Locale

Detail Information

Publications6

  1. Seo K, Kim J, Park J, Song K, Yun E, Park J, et al. PMA synergistically enhances apicularen A-induced cytotoxicity by disrupting microtubule networks in HeLa cells. BMC Cancer. 2014;14:36 pubmed publisher
    ..These results suggest that the synergy between PMA and apicularen A is involved by PKC? activation and microtubule disruption, and that may inform the development of novel approaches to treat cancer. ..
  2. Jeong S, Jing K, Kim N, Shin S, Kim S, Song K, et al. Docosahexaenoic acid-induced apoptosis is mediated by activation of mitogen-activated protein kinases in human cancer cells. BMC Cancer. 2014;14:481 pubmed publisher
    ..Together, these results indicate that DHA-induced MAPKs activation is dependent on its capacity to provoke mitochondrial ROS generation, and accounts for its cytotoxic effect in human cancer cells. ..
  3. Song K, Li G, Kim J, Jing K, Kim T, Kim J, et al. Protein-bound polysaccharide from Phellinus linteus inhibits tumor growth, invasion, and angiogenesis and alters Wnt/?-catenin in SW480 human colon cancer cells. BMC Cancer. 2011;11:307 pubmed publisher
    ..These data suggest that PL suppresses tumor growth, invasion, and angiogenesis through the inhibition of Wnt/?-catenin signaling in certain colon cancer cells. ..
  4. Lim K, Han C, Dai Y, Shen M, Wu T. Omega-3 polyunsaturated fatty acids inhibit hepatocellular carcinoma cell growth through blocking beta-catenin and cyclooxygenase-2. Mol Cancer Ther. 2009;8:3046-55 pubmed publisher
    ..These findings provide important preclinical evidence and molecular insight for utilization of omega-3 PUFAs for the chemoprevention and treatment of human HCC. ..
  5. Park H, Son W, Chae D, Lee J, Kim I, Yang W, et al. Cell cloning-on-the-spot by using an attachable silicone cylinder. Biochem Biophys Res Commun. 2016;474:768-772 pubmed publisher
    ..We tested the silicone cylinder in the monoclonal subcloning from a heterogeneous population of a breast cancer cell line, MDA-MB-231, and readily established independent MDA-MB-231 subclones showing different sublineage phenotypes. ..
  6. Gwon D, Hwang T, Ro J, Kang Y, Jeong J, Kim D, et al. High Endogenous Accumulation of ?-3 Polyunsaturated Fatty Acids Protect against Ischemia-Reperfusion Renal Injury through AMPK-Mediated Autophagy in Fat-1 Mice. Int J Mol Sci. 2017;18: pubmed publisher
    ..Collectively, ?3-PUFAs in fat-1 mice contributed to AMPK mediated autophagy activation, leading to a renoprotective response...