Young Ha Lee
Affiliation: Chungnam National University
- Quan J, Huang R, Wang Z, Huang S, Choi I, Zhou Y, et al. P2X7 receptor mediates NLRP3-dependent IL-1? secretion and parasite proliferation in Toxoplasma gondii-infected human small intestinal epithelial cells. Parasit Vectors. 2018;11:1 pubmed publisher..These results not only contribute to our understanding of the mucosal immune mechanisms of T. gondii infection but also offer new insight into the identification of innate resistance in the gut epithelium. ..
- Kim J, Lee J, Bae S, Kim Y, Park B, Choi J, et al. NADPH oxidase 4 is required for the generation of macrophage migration inhibitory factor and host defense against Toxoplasma gondii infection. Sci Rep. 2017;7:6361 pubmed publisher..Collectively, our findings indicate that Nox4-mediated ROS generation plays a central role in MIF production and resistance to T. gondii infection. ..