Soojin Lee

Summary

Affiliation: Chungnam National University
Country: Korea

Publications

  1. ncbi request reprint Molecular cloning and functional analysis of a novel oncogene, cancer-upregulated gene 2 (CUG2)
    Soojin Lee
    Department of Microbiology, Chungnam National University, Daejeon 305 764, Republic of Korea
    Biochem Biophys Res Commun 360:633-9. 2007
  2. doi request reprint Cancer-upregulated gene 2 (CUG2) overexpression induces apoptosis in SKOV-3 cells
    Sunhee Lee
    Department of Microbiology, Chungnam National University, Daejeon, Republic of Korea
    Cell Biochem Funct 28:461-8. 2010
  3. doi request reprint Newly identified tumor-associated role of human Sharpin
    Jinyoung Jung
    Department of Microbiology, Chungnam National University, Daejeon 305 764, Korea
    Mol Cell Biochem 340:161-7. 2010
  4. pmc New centromeric component CENP-W is an RNA-associated nuclear matrix protein that interacts with nucleophosmin/B23 protein
    Younghwa Chun
    Department of Microbiology and Molecular Biology, Chungnam National University, 305 764, Daejeon, Republic of Korea
    J Biol Chem 286:42758-69. 2011
  5. pmc CSN5/JAB1 interacts with the centromeric components CENP-T and CENP-W and regulates their proteasome-mediated degradation
    Younghwa Chun
    From the Department of Microbiology and Molecular Biology, Chungnam National University, Daejeon 305 764, Korea
    J Biol Chem 288:27208-19. 2013
  6. pmc Cug2 is essential for normal mitotic control and CNS development in zebrafish
    Hyun Taek Kim
    Department of Biology, Chungnam National University, Daejeon, South Korea
    BMC Dev Biol 11:49. 2011
  7. doi request reprint Sp1 and Sp3 mediate basal and serum-induced expression of human CENP-W
    Hyejin Kim
    Department of Microbiology, Brain Korea 21 Project for Biological Science, Chungnam National University, Daejeon, 305 764, Republic of Korea
    Mol Biol Rep 37:3593-600. 2010
  8. doi request reprint Cancer-upregulated gene 2 (CUG2), a new component of centromere complex, is required for kinetochore function
    Hyejin Kim
    Department of Microbiology, Chungnam National University, Daejeon 305 764, Korea
    Mol Cells 27:697-701. 2009
  9. pmc Centromere Protein (CENP)-W Interacts with Heterogeneous Nuclear Ribonucleoprotein (hnRNP) U and May Contribute to Kinetochore-Microtubule Attachment in Mitotic Cells
    Younghwa Chun
    Department of Microbiology and Molecular Biology, College of Bioscience and Biotechnology, Chungnam National University, Daejeon, Republic of Korea
    PLoS ONE 11:e0149127. 2016
  10. doi request reprint The new obesity-associated protein, neuronal growth regulator 1 (NEGR1), is implicated in Niemann-Pick disease Type C (NPC2)-mediated cholesterol trafficking
    Hyejin Kim
    Department of Microbiology and Molecular Biology, Chungnam National University, Daejeon, 34134, Republic of Korea
    Biochem Biophys Res Commun . 2016

Collaborators

Detail Information

Publications12

  1. ncbi request reprint Molecular cloning and functional analysis of a novel oncogene, cancer-upregulated gene 2 (CUG2)
    Soojin Lee
    Department of Microbiology, Chungnam National University, Daejeon 305 764, Republic of Korea
    Biochem Biophys Res Commun 360:633-9. 2007
    ....
  2. doi request reprint Cancer-upregulated gene 2 (CUG2) overexpression induces apoptosis in SKOV-3 cells
    Sunhee Lee
    Department of Microbiology, Chungnam National University, Daejeon, Republic of Korea
    Cell Biochem Funct 28:461-8. 2010
    ..Apoptotic cell death was also observed during early development of zebrafish when CUG2 was overexpressed in zebrafish embryo. We propose that high expression of CUG2 induces apoptotic cell death...
  3. doi request reprint Newly identified tumor-associated role of human Sharpin
    Jinyoung Jung
    Department of Microbiology, Chungnam National University, Daejeon 305 764, Korea
    Mol Cell Biochem 340:161-7. 2010
    ..Taken together, the results suggest that Sharpin is not an inert scaffold protein, but may play tumor-associated roles during cancer biogenesis...
  4. pmc New centromeric component CENP-W is an RNA-associated nuclear matrix protein that interacts with nucleophosmin/B23 protein
    Younghwa Chun
    Department of Microbiology and Molecular Biology, Chungnam National University, 305 764, Daejeon, Republic of Korea
    J Biol Chem 286:42758-69. 2011
    ..Our data proposed that B23 may function in the assembly of the kinetochore complex by interacting with CENP-W during interphase...
  5. pmc CSN5/JAB1 interacts with the centromeric components CENP-T and CENP-W and regulates their proteasome-mediated degradation
    Younghwa Chun
    From the Department of Microbiology and Molecular Biology, Chungnam National University, Daejeon 305 764, Korea
    J Biol Chem 288:27208-19. 2013
    ....
  6. pmc Cug2 is essential for normal mitotic control and CNS development in zebrafish
    Hyun Taek Kim
    Department of Biology, Chungnam National University, Daejeon, South Korea
    BMC Dev Biol 11:49. 2011
    ..However, the in vivo function of CUG2 has not been studied in animal models...
  7. doi request reprint Sp1 and Sp3 mediate basal and serum-induced expression of human CENP-W
    Hyejin Kim
    Department of Microbiology, Brain Korea 21 Project for Biological Science, Chungnam National University, Daejeon, 305 764, Republic of Korea
    Mol Biol Rep 37:3593-600. 2010
    ..Taken together, our results suggest that Sp1 together with Sp3 may function as the main regulator of the basal and serum-induced transcription of CENP-W...
  8. doi request reprint Cancer-upregulated gene 2 (CUG2), a new component of centromere complex, is required for kinetochore function
    Hyejin Kim
    Department of Microbiology, Chungnam National University, Daejeon 305 764, Korea
    Mol Cells 27:697-701. 2009
    ..We propose that CUG2 is a new component of the human centromeric complex that is required for proper chromosome segregation during mitosis...
  9. pmc Centromere Protein (CENP)-W Interacts with Heterogeneous Nuclear Ribonucleoprotein (hnRNP) U and May Contribute to Kinetochore-Microtubule Attachment in Mitotic Cells
    Younghwa Chun
    Department of Microbiology and Molecular Biology, College of Bioscience and Biotechnology, Chungnam National University, Daejeon, Republic of Korea
    PLoS ONE 11:e0149127. 2016
    ..CENP-W was identified as an inner centromere component that plays crucial roles in the formation of a functional kinetochore complex...
  10. doi request reprint The new obesity-associated protein, neuronal growth regulator 1 (NEGR1), is implicated in Niemann-Pick disease Type C (NPC2)-mediated cholesterol trafficking
    Hyejin Kim
    Department of Microbiology and Molecular Biology, Chungnam National University, Daejeon, 34134, Republic of Korea
    Biochem Biophys Res Commun . 2016
    ..These findings provide the first insight into the role of NEGR1 in intracellular cholesterol homeostasis, possibly explaining the missing link between NEGR1 with human obesity...
  11. doi request reprint A new kinetochore component CENP-W interacts with the polycomb-group protein EZH2 to promote gene silencing
    Wansoo Koh
    Department of Microbiology and Molecular Biology, College of Bioscience and Biotechnology, Chungnam National University, Daejeon 305 764, Republic of Korea
    Biochem Biophys Res Commun 464:256-62. 2015
    ..Collectively, this study suggests CENP-W is a novel kinetochore component that may be involved in the EZH2-mediated silencing machinery. ..
  12. doi request reprint Centromere protein W interacts with beta-transducin repeat-containing protein 1 and modulates its subcellular localization
    Yeongmi Cheon
    Department of Microbiology and Molecular Biology, Chungnam National University, Daejeon, Korea
    FEBS Lett . 2016
    ..Intriguingly, we found that overexpression of CENP-W leads to accumulation of β-TrCP1 in the nucleus. Thus, we propose that CENP-W may function as a booster of β-TrCP1 nuclear import to increase the oncogenicity of β-TrCP1...