Gi Ryang Kweon

Summary

Affiliation: Chungnam National University
Country: Korea

Publications

  1. pmc Docosahexaenoic acid-induced apoptosis is mediated by activation of mitogen-activated protein kinases in human cancer cells
    Soyeon Jeong
    Department of Biochemistry, School of Medicine, Chungnam National University, Daejeon 301 747, Korea
    BMC Cancer 14:481. 2014
  2. pmc PMA synergistically enhances apicularen A-induced cytotoxicity by disrupting microtubule networks in HeLa cells
    Kang Sik Seo
    Department of Biochemistry, College of Medicine, Chungnam National University, Daejeon, Korea
    BMC Cancer 14:36. 2014
  3. pmc DJ-1 null dopaminergic neuronal cells exhibit defects in mitochondrial function and structure: involvement of mitochondrial complex I assembly
    Jun Young Heo
    Department of Biochemistry, Chungnam National University School of Medicine, Daejeon, Korea
    PLoS ONE 7:e32629. 2012
  4. pmc Heat shock protein 70-mediated sensitization of cells to apoptosis by Carboxyl-Terminal Modulator Protein
    Longzhen Piao
    Department of Pharmacology, Daejeon Regional Cancer Center, Cancer Research Institute, Research Institute for Medical Sciences, College of Medicine, Chungnam National University, Taejeon, 301 131, Korea
    BMC Cell Biol 10:53. 2009
  5. pmc Crif1 deficiency reduces adipose OXPHOS capacity and triggers inflammation and insulin resistance in mice
    Min Jeong Ryu
    Research Center for Endocrine and Metabolic Diseases, Chungnam National University School of Medicine, Daejeon, Korea
    PLoS Genet 9:e1003356. 2013
  6. doi request reprint Omega-3-polyunsaturated fatty acids suppress pancreatic cancer cell growth in vitro and in vivo via downregulation of Wnt/Beta-catenin signaling
    Kyoung Sub Song
    Department of Biochemistry, College of Medicine, Chungnam National University, Daejeon, Korea
    Pancreatology 11:574-84. 2011
  7. doi request reprint DJ-1 mediates paraquat-induced dopaminergic neuronal cell death
    Hyun Joo Kwon
    Department of Biochemistry, School of Medicine, Chungnam National University, Daejeon, South Korea
    Toxicol Lett 202:85-92. 2011
  8. doi request reprint Apicularen A acetate induces cell death via AIF translocation and disrupts the microtubule network by down-regulating tubulin in HM7 human colon cancer cells
    Kang Sik Seo
    Department of Biochemistry, College of Medicine, Chungnam National University, Daejeon, Republic of Korea
    Biochem Biophys Res Commun 434:634-40. 2013
  9. ncbi request reprint Rottlerin induces autophagy and apoptotic cell death through a PKC-delta-independent pathway in HT1080 human fibrosarcoma cells: the protective role of autophagy in apoptosis
    Kyoung Sub Song
    Department of Biochemistry, Chungnam National University, Munhwa dong, Joong Gu, Daejeon, Korea
    Autophagy 4:650-8. 2008
  10. doi request reprint CRIF1 is essential for the synthesis and insertion of oxidative phosphorylation polypeptides in the mammalian mitochondrial membrane
    Soung Jung Kim
    Research Center for Endocrine and Metabolic Diseases, Chungnam National University School of Medicine, Daejeon 301 721, Korea
    Cell Metab 16:274-83. 2012

Collaborators

  • Kyu Lim
  • Wan Hee Yoon
  • Minho Shong
  • Tong Wu
  • Young Yun Kong
  • Jin H Son
  • Chang Han
  • Young Rae Kim
  • Hoon Kim
  • Dong Wook Kim
  • Seung Wook Ryu
  • Kang Sik Seo
  • Ji Hoon Park
  • Kyoung Sub Song
  • Jong Il Park
  • Min Jeong Ryu
  • Jun Young Heo
  • Byung Doo Hwang
  • Kaipeng Jing
  • Soung Jung Kim
  • Jong Seok Kim
  • Young Suk Jo
  • Jin Man Kim
  • Min Hee Lee
  • Eun Jin Yun
  • Soyeon Jeong
  • Chul Ho Lee
  • Hyo Kyun Chung
  • Seung Kiel Park
  • Seong Eun Lee
  • Sang Hee Lee
  • Soyeon Shin
  • Min Jeong Choi
  • Saet Byel Jung
  • Koon Soon Kim
  • Nayeong Kim
  • Jongkyeong Chung
  • Jeongsu Han
  • Surendar Tadi
  • Jung Uee Lee
  • Jeong Su Han
  • Hyun Joo Kwon
  • Longzhen Piao
  • Yeon Joo Jung
  • Soyeon Kim
  • Ki Cheol Park
  • Tae Hwa Hong
  • Young Hoon Jung
  • Yu ichi Goto
  • Yong Hyeon Yim
  • Hideyuki Hatakeyama
  • Min Chul Kwon
  • Jung Hee Shim
  • Sung Jin Kim
  • Hye Rim Oh
  • Sung Joong Kim
  • Jing X Kang
  • Valentina De Falco
  • Kwang Sun Suh
  • Jae Youl Cho
  • Jongsun Park
  • Derek P Brazil
  • Jeong Ho Seok
  • Minho Won
  • Gang Min Hur
  • Sauveur Michel Maira
  • Ragna Sack
  • Kyeong Ah Park
  • Yuwen Li
  • Janghee Hong
  • Jeong Lan Kim
  • Keum Jin Yang
  • Hee Sun Byun
  • Daniel Hess
  • Deog Yeon Jo
  • Brian A Hemmings
  • Taehoon Chun

Detail Information

Publications14

  1. pmc Docosahexaenoic acid-induced apoptosis is mediated by activation of mitogen-activated protein kinases in human cancer cells
    Soyeon Jeong
    Department of Biochemistry, School of Medicine, Chungnam National University, Daejeon 301 747, Korea
    BMC Cancer 14:481. 2014
    ....
  2. pmc PMA synergistically enhances apicularen A-induced cytotoxicity by disrupting microtubule networks in HeLa cells
    Kang Sik Seo
    Department of Biochemistry, College of Medicine, Chungnam National University, Daejeon, Korea
    BMC Cancer 14:36. 2014
    ..Apicularen A induces cytotoxicity in tumor cells through disrupting microtubule networks by tubulin down-regulation. In this study, we examined whether PMA increases apicularen A-induced cytotoxicity in HeLa cells...
  3. pmc DJ-1 null dopaminergic neuronal cells exhibit defects in mitochondrial function and structure: involvement of mitochondrial complex I assembly
    Jun Young Heo
    Department of Biochemistry, Chungnam National University School of Medicine, Daejeon, Korea
    PLoS ONE 7:e32629. 2012
    ..These mitochondrial defects induced by DJ-1mutation may be a pathological mechanism for the degeneration of dopaminergic neurons in Parkinson's disease...
  4. pmc Heat shock protein 70-mediated sensitization of cells to apoptosis by Carboxyl-Terminal Modulator Protein
    Longzhen Piao
    Department of Pharmacology, Daejeon Regional Cancer Center, Cancer Research Institute, Research Institute for Medical Sciences, College of Medicine, Chungnam National University, Taejeon, 301 131, Korea
    BMC Cell Biol 10:53. 2009
    ..In the present study we investigate novel mechanisms by which CTMP plays a role in apoptosis process...
  5. pmc Crif1 deficiency reduces adipose OXPHOS capacity and triggers inflammation and insulin resistance in mice
    Min Jeong Ryu
    Research Center for Endocrine and Metabolic Diseases, Chungnam National University School of Medicine, Daejeon, Korea
    PLoS Genet 9:e1003356. 2013
    ..These findings indicate that the OXPHOS status of adipose tissue determines its metabolic and inflammatory responses, and may cause systemic inflammation and insulin resistance...
  6. doi request reprint Omega-3-polyunsaturated fatty acids suppress pancreatic cancer cell growth in vitro and in vivo via downregulation of Wnt/Beta-catenin signaling
    Kyoung Sub Song
    Department of Biochemistry, College of Medicine, Chungnam National University, Daejeon, Korea
    Pancreatology 11:574-84. 2011
    ..However, the relationship between ω3-PUFAs and β-catenin, one of the key components of the Wnt signaling pathway, in human pancreatic cancer remains poorly characterized...
  7. doi request reprint DJ-1 mediates paraquat-induced dopaminergic neuronal cell death
    Hyun Joo Kwon
    Department of Biochemistry, School of Medicine, Chungnam National University, Daejeon, South Korea
    Toxicol Lett 202:85-92. 2011
    ..In summary, our results suggest that DJ-1 is critical to maintain mitochondrial complex I and complex I could be a key target in interaction of paraquat toxicity and DJ-1 for giving rise to PD...
  8. doi request reprint Apicularen A acetate induces cell death via AIF translocation and disrupts the microtubule network by down-regulating tubulin in HM7 human colon cancer cells
    Kang Sik Seo
    Department of Biochemistry, College of Medicine, Chungnam National University, Daejeon, Republic of Korea
    Biochem Biophys Res Commun 434:634-40. 2013
    ..Taken together, these results indicate that the mechanism of apicularen A acetate involves caspase-independent apoptotic cell death and disruption of microtubule architecture...
  9. ncbi request reprint Rottlerin induces autophagy and apoptotic cell death through a PKC-delta-independent pathway in HT1080 human fibrosarcoma cells: the protective role of autophagy in apoptosis
    Kyoung Sub Song
    Department of Biochemistry, Chungnam National University, Munhwa dong, Joong Gu, Daejeon, Korea
    Autophagy 4:650-8. 2008
    ....
  10. doi request reprint CRIF1 is essential for the synthesis and insertion of oxidative phosphorylation polypeptides in the mammalian mitochondrial membrane
    Soung Jung Kim
    Research Center for Endocrine and Metabolic Diseases, Chungnam National University School of Medicine, Daejeon 301 721, Korea
    Cell Metab 16:274-83. 2012
    ..g., Tid1. Taken together, these results suggest that CRIF1 plays a critical role in the integration of OXPHOS polypeptides into the mitochondrial membrane in mammals...
  11. pmc Mitochondrial oxidative phosphorylation reserve is required for hormone- and PPARγ agonist-induced adipogenesis
    Min Jeong Ryu
    Research Center for Endocrine and Metabolic Diseases, Chungnam National University School of Medicine, Daejeon, Korea
    Mol Cells 35:134-41. 2013
    ..Rosiglitazone treatment did not induce adipogenesis or mitochondria biogenesis in Crif1 knockout ADSCs. These results show that mitochondrial OXPHOS and Crif1 are required for rosiglitazone- and hormone-induced adipogenesis...
  12. pmc Docosahexaenoic acid induces autophagy through p53/AMPK/mTOR signaling and promotes apoptosis in human cancer cells harboring wild-type p53
    Kaipeng Jing
    Department of Biochemistry, College of Medicine, Chungnam National University, Daejeon, Korea
    Autophagy 7:1348-58. 2011
    ..Overall, our results demonstrate that autophagy contributes to the cytotoxicity of DHA in cancer cells harboring wild-type p53...
  13. doi request reprint Expression regulation and function of Pref-1 during adipogenesis of human mesenchymal stem cells (MSCs)
    Kaipeng Jing
    Department of Biochemistry, Medical School of Chungnam National University, Daejeon, Republic of Korea
    Biochim Biophys Acta 1791:816-26. 2009
    ..Taken together, our study demonstrates that IBMX accelerates accumulation of lipid in MSCs only under the circumstance that the negative effect of Pref-1 induced by IBMX on the adipogenesis is overcome by dexamethasone...
  14. doi request reprint Mitochondrial localization and regulation of BRAFV600E in thyroid cancer: a clinically used RAF inhibitor is unable to block the mitochondrial activities of BRAFV600E
    Min Hee Lee
    Department of Internal Medicine, Division of Endocrinology, Chungnam National University School of Medicine, Jung Gu, Daejeon, Korea
    J Clin Endocrinol Metab 96:E19-30. 2011
    ..The oncogenic BRAF(V600E) mutation results in an active structural conformation characterized by greatly elevated ERK activity. However, additional cellular effects caused by subcellular action of BRAF(V600E) remain to be identified...