Seung Jung Kee
Affiliation: Chonnam National University
Kwon Y, Cho Y, Kim M, Jin H, Jung H, Kang J, et al
. Mucosal-associated invariant T cells are numerically and functionally deficient in patients with mycobacterial infection and reflect disease activity. Tuberculosis (Edinb). 2015;95:267-74 pubmed publisher
..This study shows that MAIT cells are numerically and functionally deficient in TB and NTM patients and these deficiencies could contribute to immune system dysreguation in mycobacterial infection. ..
Lee O, Cho Y, Kee S, Kim M, Jin H, Lee S, et al
. Circulating mucosal-associated invariant T cell levels and their cytokine levels in healthy adults. Exp Gerontol. 2014;49:47-54 pubmed publisher
..Our data suggest that aging is associated with a reduction in circulating MAIT cells, accompanied with alterations in subset composition and cytokine profile. ..
Jin H, Kim T, Choi J, Kim M, Cho Y, Nam K, et al
. MicroRNA-155 as a proinflammatory regulator via SHIP-1 down-regulation in acute gouty arthritis. Arthritis Res Ther. 2014;16:R88 pubmed publisher
..The production of inflammatory cytokines was markedly increased in MSU crystal induced peritonitis mice. Overexpression of miR-155 in the gouty SFMC leads to suppress SHIP-1 levels and enhance proinflammatory cytokines. ..
Lee S, Nam K, Jin H, Cho Y, Lee S, Kim T, et al
. Bone destruction by receptor activator of nuclear factor ?B ligand-expressing T cells in chronic gouty arthritis. Arthritis Res Ther. 2011;13:R164 pubmed publisher
..Furthermore, our data show that MSU crystals have the potential to induce pro-resorptive cytokines, and T cells are involved in osteoclastogenesis in chronic gout. ..