Research Topics
Genomes and Genes | G Y KohSummaryAffiliation: Chonbuk National University Country: Korea Publications
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Detail Information
Publications
Characterization and expression of a novel alternatively spliced human angiopoietin-2I Kim
National Creative Research Initiatives Center for Cardiac Regeneration and Institute of Cardiovascular Research, Department of General Surgery, Chonbuk University School of Medicine, Chonju 560 180, South Korea
J Biol Chem 275:18550-6. 2000..These results suggest that Ang2(443) is a functional antagonist of Ang1 and could be an important regulator of angiogenesis during some tumorigenic and inflammatory processes...
The angiopoietin-tie2 system in coronary artery endothelium prevents oxidized low-density lipoprotein-induced apoptosisI Kim
National Creative Research Initiatives Center for Cardiac Regeneration and Institute of Cardiovascular Research, Chonbuk University School of Medicine, Chonju, South Korea
Cardiovasc Res 49:872-81. 2001..In this study, we explored the biological significance of the angiopoietin-Tie2 system in porcine coronary artery...
Angiopoietin-1 is an apoptosis survival factor for endothelial cellsH J Kwak
National Creative Research Initiatives Center for Cardiac Regeneration and Institute of Cardiovascular Research, Chonbuk National University School of Medicine, Chonju, South Korea
FEBS Lett 448:249-53. 1999..This Ang1-induced strong antiapoptotic effect in endothelial cells is a novel and intriguing finding and could be an additional description of Ang1-induced direct biological function...
Molecular cloning and characterization of a novel angiopoietin family protein, angiopoietin-3I Kim
National Creative Research Initiatives Center for Cardiac Regeneration and Institute of Cardiovascular Research, Chonbuk National University School of Medicine, Chonju, South Korea
FEBS Lett 443:353-6. 1999..Ang3 mRNA is most abundant in adrenal gland, placenta, thyroid gland, heart and small intestine in human adult tissues. Additionally, Ang3 is a secretory protein, but is not a mitogen in endothelial cells...
A novel fibroblast growth factor receptor-5 preferentially expressed in the pancreas(1)I Kim
National Creative Research Initiatives Center for Cardiac Regeneration, Chonbuk National University School of Medicine, San 2 20, Keum Am Dong, Chonju 560 180, South Korea
Biochim Biophys Acta 1518:152-6. 2001..Among 23 adult human tissues, FGFR5 mRNA is preferentially expressed in the pancreas. These results suggest that FGFR5 may provide a binding site for some other fibroblast growth factors and may regulate some pancreatic function...
Role of rho-kinase activity in angiotensin II-induced contraction of rabbit clitoral cavernosum smooth muscleJ K Park
Department of Urology, Chonbuk National University Medical School, Chonju, South Korea
Int J Impot Res 14:472-7. 2002..RhoA/Rho-kinase pathway acts in the ANG II-induced contraction independently of the NO pathway...
Vascular endothelial growth factor expression of intercellular adhesion molecule 1 (ICAM-1), vascular cell adhesion molecule 1 (VCAM-1), and E-selectin through nuclear factor-kappa B activation in endothelial cellsI Kim
National Creative Research Initiatives Center for Cardiac Regeneration, and the Department of Urology, Chonbuk National University School of Medicine, Chonju, 560-180, Republic of Korea
J Biol Chem 276:7614-20. 2001..The existence of parallel inverse signaling implies that the induction of adhesion molecule expression by VEGF is very finely regulated...
Angiopoietin-1 reduces VEGF-stimulated leukocyte adhesion to endothelial cells by reducing ICAM-1, VCAM-1, and E-selectin expressionI Kim
National Creative Research Initiatives Center for Endothelial Cells, Department of Internal Medicine, Chonbuk National University School of Medicine, Chonju, Republic of Korea
Circ Res 89:477-9. 2001..Furthermore, Ang1 reduced VEGF-induced leukocyte adhesion to HUVECs. These results demonstrate that Ang1 counteracts VEGF-induced inflammation by reducing VEGF-induced endothelial adhesiveness...
The mouse Pdgfc gene: dynamic expression in embryonic tissues during organogenesisH Ding
Samuel Lunenfeld Research Institute, Mount Sinai Hospital, 600 University Avenue, Ontario, M5G 1X5, Toronto, Canada
Mech Dev 96:209-13. 2000..Contrary to PDGF-A, Pdgfc is not expressed in the central nervous system, except in the cerebellum, and neurogenic derivatives of the neural crest cells. Pdgfc is also absent from the heart and the vascular endothelium..
Hepatic expression, synthesis and secretion of a novel fibrinogen/angiopoietin-related protein that prevents endothelial-cell apoptosisI Kim
National Creative Research Initiatives Center for Cardiac Regeneration, Institute of Cardiovascular Research, Chonbuk National University School of Medicine, Chonju, 560 180, Korea
Biochem J 346:603-10. 2000..These results suggest that HFARP may exert a protective function on endothelial cells through an endocrine action...
Molecular cloning, expression, and characterization of angiopoietin-related protein. angiopoietin-related protein induces endothelial cell sproutingI Kim
National Creative Research Initiatives Center for Cardiac Regeneration, Institute of Cardiovascular Research, Chonbuk National University School of Medicine, San 2 20, Keum Am Dong, Chonju 560 180, Republic of Korea
J Biol Chem 274:26523-8. 1999..Recombinant ARP2 protein induces sprouting in vascular endothelial cells but does not bind to the Tie1 or Tie2 receptor. These results suggest that ARP2 may exert a function on endothelial cells through autocrine or paracrine action...
Identification of alternatively spliced Na(+)-Ca2+ exchanger isoforms expressed in the heartI Kim
Department of Life Science, Pohang University of Science and Technology, Korea
Comp Biochem Physiol B Biochem Mol Biol 119:157-61. 1998..Thus, the Na(+)-Ca2+ exchanger isoforms expressed in mouse heart are consistent with being produced by alternative splicing and they may have different functions in various cell types in the mouse heart...
