H Y Kang

Summary

Affiliation: Ajou University
Country: Korea

Publications

  1. ncbi request reprint Peroxisome proliferator-activated receptors-gamma activator, ciglitazone, inhibits human melanocyte growth through induction of apoptosis
    Hee Young Kang
    Department of Dermatology, Ajou University School of Medicine, Suwon, South Korea
    Arch Dermatol Res 297:472-6. 2006
  2. ncbi request reprint FK506 increases pigmentation and migration of human melanocytes
    H Y Kang
    Department of Dermatology, Ajou University School of Medicine, Suwon 443 721, Korea
    Br J Dermatol 155:1037-40. 2006
  3. doi request reprint Imiquimod induces apoptosis of human melanocytes
    Chul Ho Kim
    Department of Otolaryngology, Ajou University School of Medicine, Suwon, Korea
    Arch Dermatol Res 302:301-6. 2010
  4. doi request reprint Melasma and aspects of pigmentary disorders in Asians
    H Y Kang
    Department of Dermatology, Ajou University School of Medicine, Suwon, Korea
    Ann Dermatol Venereol 139:S144-7. 2012
  5. doi request reprint [Melasma and aspects of pigmentary disorders in Asians]
    H Y Kang
    Service de Dermatologie, Ajou University School of Medicine, Suwon, Corée
    Ann Dermatol Venereol 139:S92-5. 2012
  6. ncbi request reprint Leukomelanoderma following acute cutaneous graft-versus-host disease
    Hee Young Kang
    Department of Dermatology, Ajou University School of Medicine, Suwon, 442 721, Korea, Republic of Korea
    Eur J Dermatol 14:146-9. 2004
  7. ncbi request reprint The dermal stem cell factor and c-kit are overexpressed in melasma
    H Y Kang
    Department of Dermatology, Ajou University School of Medicine, Suwon 443 721, Korea
    Br J Dermatol 154:1094-9. 2006
  8. doi request reprint Acquired bilateral melanosis of the neck in perimenopausal women
    J Y Park
    Department of Dermatology, Ajou University School of Medicine, San 5 Woncheon dong, Yeongtong Gu, Suwon 443 721, Korea
    Br J Dermatol 166:662-5. 2012
  9. doi request reprint Oestrogen and progesterone receptor expression in melasma: an immunohistochemical analysis
    Y H Jang
    Department of Dermatology, Ajou University School of Medicine, Suwon, Korea
    J Eur Acad Dermatol Venereol 24:1312-6. 2010
  10. doi request reprint Acquired bilateral naevus of Ota-like macules: an immunohistological analysis of dermal melanogenic paracrine cytokine networks
    J Y Lee
    Department of Dermatology, Ajou University School of Medicine, Wonchon dong, Yeongtong Gu, Suwon, Korea
    Br J Dermatol 164:580-5. 2011

Collaborators

  • J Yu Yun Lee
  • K C Park
  • S K Hann
  • S K Kim
  • M Lee
  • J H Kim
  • K H Lee
  • S Sohn
  • H D Kim
  • Jean-Paul Ortonne
  • Jeonghyun Shin
  • You Chan Kim
  • Joo Hee Ahn
  • Eun So Lee
  • En Hyung Kim
  • Y H Jang
  • E S Lee
  • Y C Kim
  • Sun Hee Jin
  • Young Jin Kim
  • Yun Jeon Kim
  • J I Na
  • J Y Park
  • D J Lee
  • Hak Sun Yu
  • Chul Ho Kim
  • Young Sook Jeong
  • S I In
  • Sang Won Yi
  • Sang Won Lee
  • Sungho Hong
  • Donghwan Shim
  • Dong Taek Cho
  • Seong Ho Tae
  • Chul Hee Choi
  • Eun Young Lee
  • Yoo Chul Lee
  • Sung Yong Seol
  • S H Yang
  • H R Choi
  • S Y Choi
  • S H Bae
  • J Ha
  • J H Sim
  • Jung Hee Pyun
  • Hye Sook Hwang
  • Sung Un Kang
  • S W Yi
  • Tae Jun Park
  • Jae Ho Han
  • Young Yi Lee
  • Sang Sun Kang
  • Soo Ik Chang
  • Byeong Wook Jeon
  • K H Bae
  • E Choi
  • C Park
  • Y S Seo
  • Y Cho

Detail Information

Publications45

  1. ncbi request reprint Peroxisome proliferator-activated receptors-gamma activator, ciglitazone, inhibits human melanocyte growth through induction of apoptosis
    Hee Young Kang
    Department of Dermatology, Ajou University School of Medicine, Suwon, South Korea
    Arch Dermatol Res 297:472-6. 2006
    ..These results indicate that melanocyte growth and apoptosis may be modulated through PPAR-gamma and that ciglitazone, a PPAR-gamma activator, inhibits growth of human melanocytes by inducing apoptosis...
  2. ncbi request reprint FK506 increases pigmentation and migration of human melanocytes
    H Y Kang
    Department of Dermatology, Ajou University School of Medicine, Suwon 443 721, Korea
    Br J Dermatol 155:1037-40. 2006
    ..Topical tacrolimus (FK506) is a potential therapeutic option for vitiligo management. Despite its clinical efficacy, the underlying mechanism of how topical tacrolimus induces repigmentation in vitiligo has scarcely been investigated...
  3. doi request reprint Imiquimod induces apoptosis of human melanocytes
    Chul Ho Kim
    Department of Otolaryngology, Ajou University School of Medicine, Suwon, Korea
    Arch Dermatol Res 302:301-6. 2010
    ..These results indicated that imiquimod induces apoptosis of melanocytes. These findings may provide a clue to understand pathogenesis of imiquimod-induced vitiligo-like hypopigmentary lesions...
  4. doi request reprint Melasma and aspects of pigmentary disorders in Asians
    H Y Kang
    Department of Dermatology, Ajou University School of Medicine, Suwon, Korea
    Ann Dermatol Venereol 139:S144-7. 2012
    ..The cases seem to represent a continuum of Riehl's melanosis. Subclinical injury or inflammation may play a role as possible causative factors for the development of the pigmentation...
  5. doi request reprint [Melasma and aspects of pigmentary disorders in Asians]
    H Y Kang
    Service de Dermatologie, Ajou University School of Medicine, Suwon, Corée
    Ann Dermatol Venereol 139:S92-5. 2012
    ..The cases seem to represent a continuum of Riehl's melanosis. Subclinical injury or inflammation may play a role as possible causative factors for the development of the pigmentation...
  6. ncbi request reprint Leukomelanoderma following acute cutaneous graft-versus-host disease
    Hee Young Kang
    Department of Dermatology, Ajou University School of Medicine, Suwon, 442 721, Korea, Republic of Korea
    Eur J Dermatol 14:146-9. 2004
    ..This observation may indicate that the production of TNF-alpha by epidermal microenvironment may be involved in postinflammatory pigmentary changes...
  7. ncbi request reprint The dermal stem cell factor and c-kit are overexpressed in melasma
    H Y Kang
    Department of Dermatology, Ajou University School of Medicine, Suwon 443 721, Korea
    Br J Dermatol 154:1094-9. 2006
    ....
  8. doi request reprint Acquired bilateral melanosis of the neck in perimenopausal women
    J Y Park
    Department of Dermatology, Ajou University School of Medicine, San 5 Woncheon dong, Yeongtong Gu, Suwon 443 721, Korea
    Br J Dermatol 166:662-5. 2012
    ..Acquired bilateral patchy or mottled pigmentation of the neck has occasionally been observed...
  9. doi request reprint Oestrogen and progesterone receptor expression in melasma: an immunohistochemical analysis
    Y H Jang
    Department of Dermatology, Ajou University School of Medicine, Suwon, Korea
    J Eur Acad Dermatol Venereol 24:1312-6. 2010
    ..However, oestrogen receptor (ER) and progesterone receptor (PR) expression in melasma-affected skin has not been investigated to date, except for one case report on ER expression...
  10. doi request reprint Acquired bilateral naevus of Ota-like macules: an immunohistological analysis of dermal melanogenic paracrine cytokine networks
    J Y Lee
    Department of Dermatology, Ajou University School of Medicine, Wonchon dong, Yeongtong Gu, Suwon, Korea
    Br J Dermatol 164:580-5. 2011
    ..However, the role of dermal factors in ABNOM remains unknown...
  11. doi request reprint Clinical and histopathological characteristics of pityriasis alba
    S I In
    Department of Dermatology, Ajou University School of Medicine, Suwon, Korea corrected
    Clin Exp Dermatol 34:591-7. 2009
    ..It is sometimes difficult to clinically differentiate PA from other hypopigmented disorders such as naevus depigmentosus...
  12. doi request reprint Immunohistochemical expression of matrix metalloproteinases in the granulomatous rosacea compared with the non-granulomatous rosacea
    Y H Jang
    Department of Dermatology, Ajou University School of Medicine, Suwon, Korea
    J Eur Acad Dermatol Venereol 25:544-8. 2011
    ..Matrix metalloproteinases (MMPs) are required for recruitment of inflammatory cells and for tissue remodelling, making way for the development of well-organized granuloma...
  13. doi request reprint Defective barrier function in melasma skin
    D J Lee
    Department of Dermatology, Ajou University School of Medicine, Suwon, Korea
    J Eur Acad Dermatol Venereol 26:1533-7. 2012
    ..These findings suggested that lesional skin may have different biophysical characteristics, and, in particular, an altered skin barrier function...
  14. ncbi request reprint Expression and function of peroxisome proliferator-activated receptors in human melanocytes
    H Y Kang
    Department of Dermatology, Ajou University School of Medicine, Suwon, Korea, 442 721
    Br J Dermatol 150:462-8. 2004
    ..The expression and function of PPARs have not been investigated in human melanocytes, although they have been widely demonstrated in keratinocytes of the skin...
  15. doi request reprint Hypopigmented keratosis: is it a hyperkeratotic variant of idiopathic guttate hypomelanosis?
    S K Kim
    Department of Dermatology, Ajou University School of Medicine, Suwon, Korea
    Clin Exp Dermatol 38:526-9. 2013
    ..These histological findings were similar to those of IGH except for the additional finding of a thicker stratum corneum in this case seem to represent a 'hyperkeratotic' variant of IGH...
  16. ncbi request reprint PPAR-gamma agonist, ciglitazone, increases pigmentation and migration of human melanocytes
    Joong Sun Lee
    Department of Dermatology, Ajou University School of Medicine, Suwon, Korea
    Exp Dermatol 16:118-23. 2007
    ..These results suggest the regulatory role of PPAR-gamma in pigmentation and migration of human melanocytes...
  17. doi request reprint Effect of tranexamic acid on melasma: a clinical trial with histological evaluation
    J I Na
    Department of Dermatology, Seoul National University College of Medicine, Seoul, Korea
    J Eur Acad Dermatol Venereol 27:1035-9. 2013
    ..Tranexamic acid (TXA), a plasmin inhibitor, is reported to improve melasma when injected locally. However, the effects of oral and topical TXA on melasma have not been well studied and the underlying mechanism remains unclear...
  18. pmc Tripartite structure of Saccharomyces cerevisiae Dna2 helicase/endonuclease
    S H Bae
    National Creative Research Initiative Center for Cell Cycle Control, Samsung Biomedical Research Institute, Sungkyunkwan University School of Medicine, 300 Chunchun-Dong, Changan-Ku, Suwon, Kyunggi-Do 440-746, Korea
    Nucleic Acids Res 29:3069-79. 2001
    ..The possible mode of regulation of Dna2 is discussed based upon our recent finding that replication protein A interacts functionally and physically with Dna2 during Okazaki fragment processing...
  19. doi request reprint Reflectance confocal microscopy for pigmentary disorders
    Hee Young Kang
    Department of Dermatology, Ajou University School of Medicine, Suwon, Korea
    Exp Dermatol 19:233-9. 2010
    ..The great advantages of non-invasive and repetitive examination of RCM may provide its usefulness not only in the diagnosis and management of pigmentary disorders, but also in researching pathogenesis of pigmentary disorders...
  20. ncbi request reprint The ultrastructural characteristics of the hair bulb of segmented heterochromia in the scalp hair
    Seonghyang Sohn
    Laboratory of Cell Biology, Department of Dermatology, Ajou University School of Medicine, 5 Wonchon dong, Paldal Ku, Suwon, 442 721, Korea South
    Eur J Dermatol 14:388-90. 2004
    ..Langerhans cells might be involved in the death of melanocytes. It is unknown how either group of melanosomes is adopted and transferred to the hair cortex producing the characteristic pattern of pigmentation...
  21. ncbi request reprint Bilateral type of nevus of Ota presenting as agminated lentigines
    Hee Young Kang
    Department of Dermatology, Ajou University School of Medicine, 5 Wonchon dong, Paldal Ku, Suwon 442 721, Korea
    Eur J Dermatol 13:205-6. 2003
    ..We diagnosed this lesion as a bilateral type of nevus of Ota presenting as agminated lentigines. The differential diagnosis from acquired bilateral nevus of Ota-like macules was made...
  22. doi request reprint LPS induces melanogenesis through p38 MAPK activation in human melanocytes
    Joo Hee Ahn
    Department of Dermatology, Ajou University School of Medicine, Suwon, South Korea
    Arch Dermatol Res 300:325-9. 2008
    ..These findings indicate that activation of p38 MAPK plays an important role in LPS-induced melanogenesis by up-regulating MITF and tyrosinase expression...
  23. doi request reprint Androgen receptor overexpression in Becker nevus: histopathologic and immunohistochemical analysis
    Young Jin Kim
    Department of Dermatology, Ajou University School of Medicine, Suwon, Korea
    J Cutan Pathol 35:1121-6. 2008
    ..There have been only a few studies of histopathologic and immunohistochemical characteristics of BN, and the etiopathogenesis has not been fully established...
  24. doi request reprint Clinical comparison of psoriasis in Korean adults and children: correlation with serum anti-streptolysin O titers
    Sue Kyung Kim
    Department of Dermatology, Ajou University School of Medicine, 5 Wonchon dong, Yeongtong Gu, Suwon, 443 721, South Korea
    Arch Dermatol Res 302:295-9. 2010
    ..Furthermore, early treatment of streptococcal infections might be beneficial in childhood psoriasis...
  25. doi request reprint Comprehensive understanding of idiopathic guttate hypomelanosis: clinical and histopathological correlation
    Sue Kyung Kim
    Department of Dermatology and Laboratory of Cell Biology, Ajou University School of Medicine, Yeongtong Gu, Suwon, Korea
    Int J Dermatol 49:162-6. 2010
    ..However, there are few recent studies that have been published on the histopathology of IGH and no comparative studies are available on the skin lesions and perilesional skin of patients with IGH...
  26. doi request reprint Methyl-beta-cyclodextrin, a specific cholesterol-binding agent, inhibits melanogenesis in human melanocytes through activation of ERK
    Sun Hee Jin
    Department of Dermatology, Ajou University School of Medicine, Suwon, South Korea
    Arch Dermatol Res 300:451-4. 2008
    ..These results suggest that cholesterol reduction by MbetaCD inhibit melanin synthesis via ERK activation and subsequent MITF downregulation...
  27. doi request reprint Histopathologic features in vitiligo
    You Chan Kim
    Department of Dermatology, Ajou University School of Medicine, Suwon, Korea maychan ajou ac kr
    Am J Dermatopathol 30:112-6. 2008
    ..In conclusion, there are a few melanocytes and melanin in some cases of vitiligo. Therefore, the diagnosis of vitiligo should be made considering these points...
  28. ncbi request reprint Clinical and histopathologic characteristics of nevus depigmentosus
    Sung Kwon Kim
    Department of Dermatology, Ajou University School of Medicine, Suwon, Korea
    J Am Acad Dermatol 55:423-8. 2006
    ..There have been only few studies of clinical and histopathologic characteristics of ND, and the etiopathogenesis is not fully established...
  29. ncbi request reprint The vascular characteristics of melasma
    En Hyung Kim
    Department of Dermatology, Ajou University School of Medicine, 5 Wonchon dong, Yeongtong Gu, Suwon 443 721, South Korea
    J Dermatol Sci 46:111-6. 2007
    ..Recently, it has been suggested that interactions between the cutaneous vasculature and melanocytes might have an influence on the development of pigmentation...
  30. doi request reprint Human melanocytes express functional Toll-like receptor 4
    Joo Hee Ahn
    Department of Dermatology, Ajou University School of Medicine, Suwon, Korea
    Exp Dermatol 17:412-7. 2008
    ..Recent studies suggest that Toll-like receptors (TLRs) play an important role in the cellular response through the recognition of pathogens...
  31. pmc Erythema nodosum: clinicopathologic correlations and their use in differential diagnosis
    Sang Won Yi
    Department of Dermatology, Ajou University School of Medicine, San 5 Wonchon Dong, Yeongtong Gu, Suwon 443 721, Korea
    Yonsei Med J 48:601-8. 2007
    ....
  32. ncbi request reprint Prevalence of dfr genes associated with integrons and dissemination of dfrA17 among urinary isolates of Escherichia coli in Korea
    Hak Sun Yu
    Department of Microbiology, School of Medicine, Kyungpook National University, 101, Dongin Dong, Jung Gu, Daegu, 700 422, Korea
    J Antimicrob Chemother 53:445-50. 2004
    ..The association of trimethoprim-resistant dfr genes with integrons was investigated in urinary Escherichia coli isolates in Korea from the last two decades...
  33. pmc Epidemiology of nalidixic acid resistance and TEM-1- and TEM-52-mediated ampicillin resistance of Shigella sonnei isolates obtained in Korea between 1980 and 2000
    Young Sook Jeong
    Department of Microbiology, Kyungpook National University School of Medicine, Taegu 700 422, Korea
    Antimicrob Agents Chemother 47:3719-23. 2003
    ..sonnei strains readily acquire resistance to ampicillin, streptomycin, trimethoprim, and sulfamethoxazole but not nalidixic acid through conjugative R-plasmids from difference sources when confronted by antibiotic selective pressures...
  34. ncbi request reprint Protein kinase B inhibits apoptosis induced by actinomycin D in ECV304 cells through phosphorylation of caspase 8
    Donghwan Shim
    Division of Life Sciences, Chungbuk National University, Cheongju 361 763, Republic of Korea
    Arch Biochem Biophys 425:214-20. 2004
    ..These results suggest that cross-talk between the PKB and caspase-8 pathways may regulate the balance between cell survival and cell death in ECV304...
  35. ncbi request reprint Friction melanosis and striae distensa caused by stretch training on a bench press
    Hee Young Kang
    J Dermatol 32:765-6. 2005
  36. pmc Two cases of lichen planus pigmentosus presenting with a linear pattern
    Sungho Hong
    Department of Dermatology, Ajou University School of Medicine, 5 Wonchon dong, Paldal Gu, Suwon 442 721, Korea
    J Korean Med Sci 19:152-4. 2004
    ..These patients, to the best of our knowledge, are the first cases of LPP presenting with a linear pattern. LPP should be considered in the differential diagnosis of linear hyperpigmented skin lesions...
  37. ncbi request reprint Protein kinase B inhibits endostatin-induced apoptosis in HUVECs
    Hee Young Kang
    Division of Life Sciences, Chungbuk National University, Cheongju, 361 763, Korea
    J Biochem Mol Biol 39:97-104. 2006
    ..It was found that the inhibition of PI3K/PKB significantly increased endostatin-induced apoptosis, and that endostatininduced cell death is physiologically linked to PKB-mediated cell survival through caspase-8...
  38. pmc Congenital atrophoderma of Pasini and Pierini
    Sung Kwon Kim
    Department of Dermatology, Ajou University School of Medicine, Suwon, Korea
    J Korean Med Sci 21:169-71. 2006
    ..The histologic findings were consistent with atrophoderma. This patient, to the best of our knowledge, is the first case of atrophoderma with an onset since birth...
  39. ncbi request reprint Is apoptosis involved in the development of balloon cell nevus? Suggestion from a case report
    Yun Jeon Kim
    J Am Acad Dermatol 56:1069-70. 2007
  40. ncbi request reprint Linear lichenoid graft versus host disease: an unusual configuration following Blaschko's lines
    Sang Won Lee
    J Dermatol 33:583-4. 2006
  41. ncbi request reprint Partial unilateral lentiginosis with ocular involvement
    En Hyung Kim
    Eur J Dermatol 16:582-3. 2006
  42. ncbi request reprint Differences in phenotypic and genotypic traits against antimicrobial agents between Acinetobacter baumannii and Acinetobacter genomic species 13TU
    Jung Hoon Lee
    Department of Microbiology, Kyungpook National University School of Medicine, Daegu 700 422, Republic of Korea
    J Antimicrob Chemother 59:633-9. 2007
    ..To investigate the differences in antimicrobial susceptibility and resistance mechanisms against imipenem between Acinetobacter baumannii and Acinetobacter genomic species 13TU...
  43. ncbi request reprint Pigmentation after using topical tacrolimus to treat lichen sclerosus: possible role of stem cell factor
    Young Jin Kim
    J Am Acad Dermatol 57:S125-7. 2007
  44. ncbi request reprint Giant molluscum contagiosum of immunocompetent children occurring on the anogenital area
    Sung Kwon Kim
    Department of Dermatology, Ajou University School of Medicine, 5 Wonchon dong, Yeongtong Gu, Suwon, South Korea
    Eur J Dermatol 17:537-8. 2007
  45. ncbi request reprint Lithium chloride increases pigmentation of melanoma cells by interfering with the inositol phosphate pathway
    Hee Young Kang
    Department of Dermatology, Ajou University School of Medicine, Suwon, 442 721, Republic of Korea
    Arch Dermatol Res 294:426-9. 2002