Research Topics
| B Z AhnSummaryCountry: Korea Publications
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Detail Information
Publications
Inhibitory effect of bupleuri radix saponins on adhesion of some solid tumor cells and relation to hemolytic action: screening of 232 herbal drugs for anti-cell adhesionB Z Ahn
College of Pharmacy, Chungnam National University, Taejon, Korea
Planta Med 64:220-4. 1998..Taken together, it is suggested that the mechanism for anti-cell adhesive activity of saikosaponin may resemble that for their hemolytic action...
Naphthazarin derivatives (VII): antitumor action against ICR mice bearing ascitic S-180 cellsG Y Song
College of Pharmacy, Chungnam National University, Taejon, Korea
Arch Pharm Res 24:35-8. 2001..Some of 6-(1-propyloxyalkyl)-DMNQ derivatives with an alkyl group of butyl to octyl moiety showed T/C values of >400%..
Syntheses of certain 3-aryl-2-propenoates and evaluation of their cytotoxicityN H Nam
College of Pharmacy, Chungnam National University, Taejon, South Korea
Bioorg Med Chem Lett 11:1173-6. 2001..It was found that the ortho- or para-dihydroxy funtionality on the aryl ring was essential for the cytotoxicity of cinnamates. Compounds 8ba, 8bb and 9aa, 9ab showed potent cytotoxicity against various tumor cell lines...
Naphthazarin derivatives (VII): antitumor action against ICR mice bearing ascitic S-180 cellsG Y Song
College of Pharmacy, Chungnam National University, Taejon, Korea
Arch Pharm Res 24:190-3. 2001..Some of 6-(1-propyloxyalkyl)-DMNQ derivatives with an alkyl group of butyl to octyl moiety showed T/C values of >400%...
Naphthazarin derivatives (VIII): Synthesis, inhibitory effect on DNA topoisomerase-I, and antiproliferative activity of 6-(1-acyloxyalkyl)-5,8-dimethoxy-1,4-naphthoquinonesY Kim
College of Pharmacy, Chungnam National University, Taejon 305-764, Korea
Arch Pharm (Weinheim) 334:318-22. 2001..It is noteworthy that 6-(1-heptanoyloxyethyl)-DMNQ exhibited both the most potent Topo I inhibitory activity (IC50, 11.5 microM) and the greatest antiproliferative activity (ED50, 0.05 microM) upon L1210 cells...
Combretoxazolones: synthesis, cytotoxicity and antitumor activityN H Nam
College of Pharmacy, Chungnam National University, Taejon 305-764, Republic of Korea
Bioorg Med Chem Lett 11:3073-6. 2001..Compound 6g exhibited a significant antitumor activity in BDF1 mice bearing B16 murine melanoma cells with inhibition rates of 67 and 61% at 100 and 30 mg/kg/day, respectively...
