Edgar E Kooijman

Summary

Publications

  1. ncbi An electrostatic/hydrogen bond switch as the basis for the specific interaction of phosphatidic acid with proteins
    Edgar E Kooijman
    Department Biochemistry of Membranes, Bijvoet Center, Institute of Biomembranes, Utrecht University, Utrecht 3584 CH, The Netherlands
    J Biol Chem 282:11356-64. 2007
  2. ncbi Membrane organization and ionization behavior of the minor but crucial lipid ceramide-1-phosphate
    Edgar E Kooijman
    Physics Department, Kent State University, Kent, Ohio, USA
    Biophys J 94:4320-30. 2008
  3. ncbi What makes the bioactive lipids phosphatidic acid and lysophosphatidic acid so special?
    Edgar E Kooijman
    Department of Biochemistry of Membranes, Bijvoet Center, Institute of Biomembranes, Utrecht University, Utrecht, The Netherlands
    Biochemistry 44:17007-15. 2005
  4. ncbi Ionization properties of phosphatidylinositol polyphosphates in mixed model membranes
    Edgar E Kooijman
    Department of Biological Sciences, Kent State University, Kent, Ohio 44242, USA
    Biochemistry 48:9360-71. 2009
  5. ncbi Spontaneous curvature of phosphatidic acid and lysophosphatidic acid
    Edgar E Kooijman
    Department of Biochemistry of Membranes, Center for Biomembranes and Lipid Enzymology, Utrecht University, Padualaan 8, 3584 CH Utrecht, The Netherlands
    Biochemistry 44:2097-102. 2005
  6. ncbi Phosphatidylinositol-4,5-bisphosphate ionization and domain formation in the presence of lipids with hydrogen bond donor capabilities
    Zachary T Graber
    Kent State University, Department of Chemistry and Biochemistry, PO Box 5190, Kent, OH 44240, USA
    Chem Phys Lipids 165:696-704. 2012
  7. ncbi Structure of ceramide-1-phosphate at the air-water solution interface in the absence and presence of Ca2+
    Edgar E Kooijman
    Department of Biological Sciences, Kent State University, Kent, Ohio 44242
    Biophys J 96:2204-15. 2009
  8. ncbi Modulation of membrane curvature by phosphatidic acid and lysophosphatidic acid
    Edgar E Kooijman
    Department of Biochemistry of Membranes, Center for Biomembranes and Lipid Enzymology, Institute of Biomembranes, Utrecht University, 3584 CH Utrecht, The Netherlands
    Traffic 4:162-74. 2003
  9. ncbi Ionization Behavior of Polyphosphoinositides Determined via the Preparation of pH Titration Curves Using Solid-State (31)P NMR
    Zachary T Graber
    Chemistry Department, Kent State University, Kent, OH, USA
    Methods Mol Biol 1009:129-42. 2013

Collaborators

Detail Information

Publications9

  1. ncbi An electrostatic/hydrogen bond switch as the basis for the specific interaction of phosphatidic acid with proteins
    Edgar E Kooijman
    Department Biochemistry of Membranes, Bijvoet Center, Institute of Biomembranes, Utrecht University, Utrecht 3584 CH, The Netherlands
    J Biol Chem 282:11356-64. 2007
    ..In combination with the special packing properties of PA, PA may well be nature's preferred membrane lipid for interfacial insertion of positively charged membrane protein domains...
  2. ncbi Membrane organization and ionization behavior of the minor but crucial lipid ceramide-1-phosphate
    Edgar E Kooijman
    Physics Department, Kent State University, Kent, Ohio, USA
    Biophys J 94:4320-30. 2008
    ..In particular, the similarities and differences between ceramide and Cer-1-P may be relevant in explaining some of their physiological roles...
  3. ncbi What makes the bioactive lipids phosphatidic acid and lysophosphatidic acid so special?
    Edgar E Kooijman
    Department of Biochemistry of Membranes, Bijvoet Center, Institute of Biomembranes, Utrecht University, Utrecht, The Netherlands
    Biochemistry 44:17007-15. 2005
    ..We propose that this hydrogen bonding property of (L)PA is involved in the various cellular functions of these lipids...
  4. ncbi Ionization properties of phosphatidylinositol polyphosphates in mixed model membranes
    Edgar E Kooijman
    Department of Biological Sciences, Kent State University, Kent, Ohio 44242, USA
    Biochemistry 48:9360-71. 2009
    ....
  5. ncbi Spontaneous curvature of phosphatidic acid and lysophosphatidic acid
    Edgar E Kooijman
    Department of Biochemistry of Membranes, Center for Biomembranes and Lipid Enzymology, Utrecht University, Padualaan 8, 3584 CH Utrecht, The Netherlands
    Biochemistry 44:2097-102. 2005
    ..3 x 10(2) A). Our quantitative data on the spontaneous radius of curvature of PA and LPA at a physiological pH and salt concentration will be instrumental in developing future models of biomembrane fission...
  6. ncbi Phosphatidylinositol-4,5-bisphosphate ionization and domain formation in the presence of lipids with hydrogen bond donor capabilities
    Zachary T Graber
    Kent State University, Department of Chemistry and Biochemistry, PO Box 5190, Kent, OH 44240, USA
    Chem Phys Lipids 165:696-704. 2012
    ..The cooperative formation of PI/PI(4,5)P(2) mixed domains has potentially important ramifications for the spatial organization of phosphoinositide mediated signaling events...
  7. ncbi Structure of ceramide-1-phosphate at the air-water solution interface in the absence and presence of Ca2+
    Edgar E Kooijman
    Department of Biological Sciences, Kent State University, Kent, Ohio 44242
    Biophys J 96:2204-15. 2009
    ..These results can be qualitatively understood based on the molecular structure of Cer-1-P and the electrostatic/hydrogen-bond interactions of its phosphomonoester headgroup. Biological implications of our results are also discussed...
  8. ncbi Modulation of membrane curvature by phosphatidic acid and lysophosphatidic acid
    Edgar E Kooijman
    Department of Biochemistry of Membranes, Center for Biomembranes and Lipid Enzymology, Institute of Biomembranes, Utrecht University, 3584 CH Utrecht, The Netherlands
    Traffic 4:162-74. 2003
    ..Alternative models for the regulation of membrane fission based on the strong dependence of the molecular shape of (lyso)phosphatidic acid on pH and divalent cations are also discussed...
  9. ncbi Ionization Behavior of Polyphosphoinositides Determined via the Preparation of pH Titration Curves Using Solid-State (31)P NMR
    Zachary T Graber
    Chemistry Department, Kent State University, Kent, OH, USA
    Methods Mol Biol 1009:129-42. 2013
    ..Access to a solid-state, i.e., magic angle spinning, capable NMR spectrometer is assumed. The procedures described here are valid for a Bruker instrument, but can be adapted for other spectrometers as needed...