Serum brain-derived neurotrophic factor, nerve growth factor and neurotrophin-3 levels in dementiaDildar Konukoglu
Ataköy Konakları, D2 1, Daire 10, Bakirkoy, Istanbul, Turkey
Acta Neurol Belg 112:255-60. 2012
..However, future studies are required to determine the importance of NFs...
Relationship between plasma leptin and zinc levels and the effect of insulin and oxidative stress on leptin levels in obese diabetic patientsDildar Konukoglu
Cerrahpasa Medical Faculty, Department of Biochemistry, Istanbul University, Istanbul, Turkey
J Nutr Biochem 15:757-60. 2004
..We conclude that zinc may be a mediator of the effects of leptin, although the detailed mechanism is still unknown and requires further investigation. Free radical induced mechanism(s) may be involved in this process...
- The relationship between plasma viscosity and cholesterol in postmenopausal women on hormone replacement therapy
D Konukoglu
Department of Biochemistry of Cerrahpasa Medical Faculty, University of Istanbul, Turkey
Clin Hemorheol Microcirc 22:223-8. 2000
..These data demonstrated that HRT has beneficial effect on plasma viscosity; mainly in normocholesterolemic post menopausal women...
- Relation of erythrocyte Na+-K+ ATPase activity and cholesterol and oxidative stress in patients with type 2 diabetes mellitus
Dildar Konukoglu
Department of Biochemistry, Cerrahpasa Medical Faculty, Istanbul University, Istanbul, Turkey
Clin Invest Med 26:279-84. 2003
..We, therefore, carried out a study in type 2 diabetic patients to determine the relationships of erythrocyte Na+-K+ ATPase activity, plasma cholesterol and oxidative stress in this population...
- Impaired glucose tolerance: its relevance to early endothelial dysfunction
D Konukoglu
Department of Biochemistry, Cerrahpasa Medical Faculty, Istanbul University, Turkey
Horm Metab Res 35:607-10. 2003
..38, p< 0.01). We suggest that NO availability was decreased when the blood glucose levels were only moderately elevated above normal levels. This might be related with the enhanced oxidative stress...
- Plasma homocysteine levels in obese and non-obese subjects with or without hypertension; its relationship with oxidative stress and copper
Dildar Konukoglu
Istanbul University, Biochemistry Department of Cerrahpasa Medical Faculty, Istanbul, Turkey
Clin Biochem 36:405-8. 2003
..The relationship between plasma total Homocysteine (tHcy) and oxidative stress and plasma levels of lipids, insulin and copper levels were investigated in obese and nonobese hypertensives...
- Plasma and erythrocytes antioxidant status and trace element levels in proteinuric patients with moderate glomerular function
D Konukoglu
Department of Biochemistry, University of Istanbul, Cerrahpasa Medical Faculty, Turkey
J Trace Elem Med Biol 15:119-22. 2001
..This study was concluded that cellular antioxidant activity decreases in proteinuric patients with moderate glomerular function. This may increase lipid peroxidation reactions by causing oxidative stress in erythrocyte membranes...
- Protein carbonyl content in erythrocyte membranes in type 2 diabetic patients
D Konukoglu
Department of Biochemistry, Cerrahpasa Medical Faculty, Istanbul University, Turkey
Horm Metab Res 34:367-70. 2002
..001). These results suggest that impaired glycemic control is connected to protein oxidation, and protein oxidation may be related to underlying metabolic abnormalities and complications of diabetes...
- Plasma leptin levels in obese and non-obese postmenopausal women before and after hormone replacement therapy
D Konukoglu
Department of Biochemistry, Cerrahpasa Medical Faculty, Istanbul University, Fatih Sitesi, B 4 Blok, Daire 5, Silivvikapi, Fatih, Istanbul, Turkey
Maturitas 36:203-7. 2000
..the aim of this study was to investigate the effect of hormone replacement therapy (HRT) on plasma leptin levels in postmenopausal women, and the relationship between the plasma leptin levels and obesity...
- Effects of oxidative stress on the erythrocyte Na+,K+ ATPase activity in female hyperthyroid patients
D Konukoglu
Department of Biochemistry, Cerrahpasa Medical Faculty, Istanbul University, Turkey
J Toxicol Environ Health A 63:289-95. 2001
..Our results might help to clarify the effects of the oxidative mechanisms on the erythrocyte membrane Na+,K+-ATPase activity in hyperthyroid patients...
- Plasma total homocysteine concentrations in obese and non-obese female patients with type 2 diabetes mellitus; its relations with plasma oxidative stress and nitric oxide levels
Dildar Konukoglu
Istanbul University, Biochemistry Department of Cerrahpasa Medical Faculty, Istanbul, Turkey
Clin Hemorheol Microcirc 33:41-6. 2005
..We thought that Hcy might have a permissive role on the endothelium damage through free radical generating systems and the presence of obesity the free radical induced-damage has been elevated in diabetic patients...
- Abdominal aortic aneurysm or aortic occlusive disease: role of trace element imbalance
Cengiz Koksal
Department of Cardiovascular Surgery, Sureyyapasa Thoracic and Cardiovascular Disease Hospital, Istanbul, Turkey
Angiology 58:191-5. 2007
..001 for each). These results suggest that higher oxidative stress as a result of higher Fe and Cu levels in the AAA, compared with AOD, may be one of the contributing factors in aneurysmal formation as a result of promoted wall erosion...
- The relationship between plasma asymmetrical dimethyl-L-arginine and inflammation and adhesion molecule levels in subjects with normal, impaired, and diabetic glucose tolerance
Dildar Konukoglu
Istanbul University, Cerrahpasa Faculty of Medicine, Department of Biochemistry, Istanbul 34303, Turkey
Metabolism 57:110-5. 2008
..A complex interrelation could exist between ADMA and inflammation, and mechanisms involved in endothelial dysfunction are multifactorial at the prediabetic and diabetic state...
- Plasma protein carbonyl and thiol stress before and after laparoscopic gastric banding in morbidly obese patients
Hafize Uzun
Istanbul University, Cerrahpasa Medical Faculty, Department of Biochemistry, Turkey
Obes Surg 17:1367-73. 2007
..The aim of this study is to examine the relationship between oxidative plasma protein and thiol stress and weight loss after laparoscopic adjustable gastric banding (LAGB)...
- Epidural anesthesia may attenuate lipid peroxidation during aorto-femoral surgery
Lale Yüceyar
Department of Anesthesiology, Istanbul University Cerrahpasa Medical Faculty, Istanbul, Turkey
Can J Anaesth 51:465-71. 2004
....
- Plasma leptin and its relationship with lipid peroxidation and nitric oxide in obese female patients with or without hypertension
Dildar Konukoglu
Department of Biochemistry, Cerrahpasa Medical Faculty, Istanbul University, Istanbul, Turkey
Arch Med Res 37:602-6. 2006
..We investigated the association of plasma leptin levels with plasma lipid peroxidation and nitric oxide metabolites (NOx) in obese hypertensive atherosclerosis model...
- Association of plasma viscosity with cardiovascular risk factors in obesity: an old marker, a new insight
Meltem Ercan
Istanbul University, Cerrahpasa Medical Faculty, Biophysics Department, Istanbul, Turkey
Clin Hemorheol Microcirc 35:441-6. 2006
....
- The effects of renal replacement therapy on plasma, asymmetric dimethylarginine, nitric oxide and C-reactive protein levels
Halfize Uzun
Istanbul University, Cerrahpasa Medical Faculty, Department of Biochemistry, Istanbul, Turkey
Clin Invest Med 31:E1-7. 2008
..The aim of the study was to investigate the relationship between renal replacement therapy and endothelial dysfunction...
- Relationship among plasma secretory phospholipase A2, oxidized low density lipoprotein & paraoxonase activities in hypertensive subjects treated with angiotensin converting enzyme inhibitors
Dildar Konukoglu
Istanbul University, Cerrahpasa Faculty of Medicine, Department of Biochemistry, Istanbul, Turkey
Indian J Med Res 129:390-4. 2009
..This study was undertaken to investigate the relationship between oxidative and inflammatory markers in hypertensive patients with or without antihypertensive drug treatment...
- The effects of exposure of 60Co on the oxidant/antioxidant status among radiation victims
Mustafa Demir
Department of Nuclear Medicine, Istanbul University, Istanbul, Turkey
J Environ Radioact 64:19-25. 2003
..It is suggested here that antioxidant supplementation therapy might be effective in preventing the harmful effects of 60Co radiation among radiation victims...
- Aprotinin ameliorates ischemia/reperfusion injury in a rat hind limb model
Cengiz Koksal
Istanbul University, Cerrahpasa Medical Faculty, Department of Cardiovascular Surgery, P O Box 26, Cerrahpasa, 34301, Istanbul, Turkey
Vascul Pharmacol 41:125-9. 2004
..006, p=0.001). These results suggest that aprotinin, a potent anti-inflammatory drug, is more useful than alpha-tocopherol, a powerful antioxidant, for attenuating muscle injury after I/R...
- Relation of serum vascular endothelial growth factor as an angiogenesis biomarker with nitric oxide & urokinase-type plasminogen activator in breast cancer patients
Dildar Konukoglu
Department of Biochemistry, Cerrahpasa Medical Faculty, Istanbul University, Istanbul, Turkey
Indian J Med Res 125:747-51. 2007
..The aim of this study was to investigate the relationship between serum levels of VEGF and NO and u-PA in patients with breast cancer...
- The effects of cholesterol levels on hemorheological parameters in diabetic patients
Meltem Ercan
Department of Biophysics, University of Istanbul, Cerrahpasa Medical Faculty, Istanbul, Turkey
Clin Hemorheol Microcirc 26:257-63. 2002
..001). Our data suggest that elevated plasma cholesterol may impair RBC deformability and increase in blood and plasma viscosity by an additional effect to hyperglycemia in type 2 diabetic patients...
- Increased maternal serum and cord blood fibronectin concentrations in preeclampsia are associated with higher placental hyaluronic acid and hydroxyproline content
Hafize Uzun
Istanbul University, Cerrahpasa Medical Faculty, Department of Biochemistry, Istanbul, Turkey
Hypertens Pregnancy 29:153-62. 2010
..The purpose of this study was to examine the relationship between maternal serum FN levels and the extracellular matrix molecule contents of placental tissue, such as FN, hyaluronic acid (HA) and hydroxyproline (HP) levels...
- Is midazolam effective as an antioxidant in preventing reperfusion injury in rat kidney?
Ugur Erol
Department of Anesthesiology and Reanimation, University of Marmara, School of Medicine, Istanbul, Turkey
Int Urol Nephrol 34:121-7. 2002
..Right kidneys were histopathologically normal in both groups. We concluded that within this dosage midazolam does not have any antioxidant effect in reperfused rat kidneys following ischemia...
- Plasma adhesion and inflammation markers: asymmetrical dimethyl-L-arginine and secretory phospholipase A2 concentrations before and after laparoscopic gastric banding in morbidly obese patients
Dildar Konukoglu
Istanbul University, Cerrahpasa Medical Faculty, Department of Biochemistry, Istanbul, Turkey
Obes Surg 17:672-8. 2007
..The aim of this study was to examine the relationship between subclinical inflammation and weight loss by laparoscopic adjustable gastric banding (LAGB)...
- Glutathione and glutathione-related enzymes in colorectal cancer patients
Eyup Ilker Saygili
Department of Biochemistry, Cerrahpasa Medical Faculty, University of Istanbul, Istanbul, Turkey
J Toxicol Environ Health A 66:411-5. 2003
..Our results suggest that oxidative stress may play an important role in colorectal tumorigenesis and that these events have no effect on the clinical grading of the colorectal tumor...
- Plasma oxidative and inflammatory markers in patients with idiopathic Parkinson's disease
Gülnur Andican
Department of Biochemistry, Cerrahpasa Medical Faculty, Istanbul University, Istanbul, Turkey
Acta Neurol Belg 112:155-9. 2012
..Establishing the roles of these pathological processes in PD might be the key to effective therapy at an early stage by antioxidants and/or anti-inflammatory drugs...
- Attenuation of ischemia/reperfusion injury by N-acetylcysteine in a rat hind limb model
Cengiz Koksal
Sureyyapasa Thoracic and Cardiovascular Disease Hospital, Departmemnt of Cardiovascular Surgery, Istanbul, Turkey
J Surg Res 111:236-9. 2003
..In present study, we examined the protective effect of NAC in a rat hind limb ischemia/ reperfusion model. Dimethyl-sulfoxide (DMSO), a well-known antioxidant was also tested for comparison...
