Dildar Konukoglu

Summary

Publications

  1. doi request reprint Serum brain-derived neurotrophic factor, nerve growth factor and neurotrophin-3 levels in dementia
    Dildar Konukoglu
    Ataköy Konakları, D2 1, Daire 10, Bakirkoy, Istanbul, Turkey
    Acta Neurol Belg 112:255-60. 2012
  2. ncbi request reprint The relationship between plasma viscosity and cholesterol in postmenopausal women on hormone replacement therapy
    D Konukoglu
    Department of Biochemistry of Cerrahpasa Medical Faculty, University of Istanbul, Turkey
    Clin Hemorheol Microcirc 22:223-8. 2000
  3. ncbi request reprint Relationship between plasma leptin and zinc levels and the effect of insulin and oxidative stress on leptin levels in obese diabetic patients
    Dildar Konukoglu
    Cerrahpasa Medical Faculty, Department of Biochemistry, Istanbul University, Istanbul, Turkey
    J Nutr Biochem 15:757-60. 2004
  4. ncbi request reprint Relation of erythrocyte Na+-K+ ATPase activity and cholesterol and oxidative stress in patients with type 2 diabetes mellitus
    Dildar Konukoglu
    Department of Biochemistry, Cerrahpasa Medical Faculty, Istanbul University, Istanbul, Turkey
    Clin Invest Med 26:279-84. 2003
  5. ncbi request reprint Impaired glucose tolerance: its relevance to early endothelial dysfunction
    D Konukoglu
    Department of Biochemistry, Cerrahpasa Medical Faculty, Istanbul University, Turkey
    Horm Metab Res 35:607-10. 2003
  6. ncbi request reprint Plasma homocysteine levels in obese and non-obese subjects with or without hypertension; its relationship with oxidative stress and copper
    Dildar Konukoglu
    Istanbul University, Biochemistry Department of Cerrahpasa Medical Faculty, Istanbul, Turkey
    Clin Biochem 36:405-8. 2003
  7. ncbi request reprint Plasma leptin levels in obese and non-obese postmenopausal women before and after hormone replacement therapy
    D Konukoglu
    Department of Biochemistry, Cerrahpasa Medical Faculty, Istanbul University, Fatih Sitesi, B 4 Blok, Daire 5, Silivvikapi, Fatih, Istanbul, Turkey
    Maturitas 36:203-7. 2000
  8. ncbi request reprint Effects of oxidative stress on the erythrocyte Na+,K+ ATPase activity in female hyperthyroid patients
    D Konukoglu
    Department of Biochemistry, Cerrahpasa Medical Faculty, Istanbul University, Turkey
    J Toxicol Environ Health A 63:289-95. 2001
  9. ncbi request reprint Protein carbonyl content in erythrocyte membranes in type 2 diabetic patients
    D Konukoglu
    Department of Biochemistry, Cerrahpasa Medical Faculty, Istanbul University, Turkey
    Horm Metab Res 34:367-70. 2002
  10. ncbi request reprint Plasma and erythrocytes antioxidant status and trace element levels in proteinuric patients with moderate glomerular function
    D Konukoglu
    Department of Biochemistry, University of Istanbul, Cerrahpasa Medical Faculty, Turkey
    J Trace Elem Med Biol 15:119-22. 2001

Collaborators

Detail Information

Publications32

  1. doi request reprint Serum brain-derived neurotrophic factor, nerve growth factor and neurotrophin-3 levels in dementia
    Dildar Konukoglu
    Ataköy Konakları, D2 1, Daire 10, Bakirkoy, Istanbul, Turkey
    Acta Neurol Belg 112:255-60. 2012
    ..However, future studies are required to determine the importance of NFs...
  2. ncbi request reprint The relationship between plasma viscosity and cholesterol in postmenopausal women on hormone replacement therapy
    D Konukoglu
    Department of Biochemistry of Cerrahpasa Medical Faculty, University of Istanbul, Turkey
    Clin Hemorheol Microcirc 22:223-8. 2000
    ..These data demonstrated that HRT has beneficial effect on plasma viscosity; mainly in normocholesterolemic post menopausal women...
  3. ncbi request reprint Relationship between plasma leptin and zinc levels and the effect of insulin and oxidative stress on leptin levels in obese diabetic patients
    Dildar Konukoglu
    Cerrahpasa Medical Faculty, Department of Biochemistry, Istanbul University, Istanbul, Turkey
    J Nutr Biochem 15:757-60. 2004
    ..We conclude that zinc may be a mediator of the effects of leptin, although the detailed mechanism is still unknown and requires further investigation. Free radical induced mechanism(s) may be involved in this process...
  4. ncbi request reprint Relation of erythrocyte Na+-K+ ATPase activity and cholesterol and oxidative stress in patients with type 2 diabetes mellitus
    Dildar Konukoglu
    Department of Biochemistry, Cerrahpasa Medical Faculty, Istanbul University, Istanbul, Turkey
    Clin Invest Med 26:279-84. 2003
    ..We, therefore, carried out a study in type 2 diabetic patients to determine the relationships of erythrocyte Na+-K+ ATPase activity, plasma cholesterol and oxidative stress in this population...
  5. ncbi request reprint Impaired glucose tolerance: its relevance to early endothelial dysfunction
    D Konukoglu
    Department of Biochemistry, Cerrahpasa Medical Faculty, Istanbul University, Turkey
    Horm Metab Res 35:607-10. 2003
    ..38, p< 0.01). We suggest that NO availability was decreased when the blood glucose levels were only moderately elevated above normal levels. This might be related with the enhanced oxidative stress...
  6. ncbi request reprint Plasma homocysteine levels in obese and non-obese subjects with or without hypertension; its relationship with oxidative stress and copper
    Dildar Konukoglu
    Istanbul University, Biochemistry Department of Cerrahpasa Medical Faculty, Istanbul, Turkey
    Clin Biochem 36:405-8. 2003
    ..The relationship between plasma total Homocysteine (tHcy) and oxidative stress and plasma levels of lipids, insulin and copper levels were investigated in obese and nonobese hypertensives...
  7. ncbi request reprint Plasma leptin levels in obese and non-obese postmenopausal women before and after hormone replacement therapy
    D Konukoglu
    Department of Biochemistry, Cerrahpasa Medical Faculty, Istanbul University, Fatih Sitesi, B 4 Blok, Daire 5, Silivvikapi, Fatih, Istanbul, Turkey
    Maturitas 36:203-7. 2000
    ..the aim of this study was to investigate the effect of hormone replacement therapy (HRT) on plasma leptin levels in postmenopausal women, and the relationship between the plasma leptin levels and obesity...
  8. ncbi request reprint Effects of oxidative stress on the erythrocyte Na+,K+ ATPase activity in female hyperthyroid patients
    D Konukoglu
    Department of Biochemistry, Cerrahpasa Medical Faculty, Istanbul University, Turkey
    J Toxicol Environ Health A 63:289-95. 2001
    ..Our results might help to clarify the effects of the oxidative mechanisms on the erythrocyte membrane Na+,K+-ATPase activity in hyperthyroid patients...
  9. ncbi request reprint Protein carbonyl content in erythrocyte membranes in type 2 diabetic patients
    D Konukoglu
    Department of Biochemistry, Cerrahpasa Medical Faculty, Istanbul University, Turkey
    Horm Metab Res 34:367-70. 2002
    ..001). These results suggest that impaired glycemic control is connected to protein oxidation, and protein oxidation may be related to underlying metabolic abnormalities and complications of diabetes...
  10. ncbi request reprint Plasma and erythrocytes antioxidant status and trace element levels in proteinuric patients with moderate glomerular function
    D Konukoglu
    Department of Biochemistry, University of Istanbul, Cerrahpasa Medical Faculty, Turkey
    J Trace Elem Med Biol 15:119-22. 2001
    ..This study was concluded that cellular antioxidant activity decreases in proteinuric patients with moderate glomerular function. This may increase lipid peroxidation reactions by causing oxidative stress in erythrocyte membranes...
  11. ncbi request reprint Plasma total homocysteine concentrations in obese and non-obese female patients with type 2 diabetes mellitus; its relations with plasma oxidative stress and nitric oxide levels
    Dildar Konukoglu
    Istanbul University, Biochemistry Department of Cerrahpasa Medical Faculty, Istanbul, Turkey
    Clin Hemorheol Microcirc 33:41-6. 2005
    ..We thought that Hcy might have a permissive role on the endothelium damage through free radical generating systems and the presence of obesity the free radical induced-damage has been elevated in diabetic patients...
  12. ncbi request reprint Abdominal aortic aneurysm or aortic occlusive disease: role of trace element imbalance
    Cengiz Koksal
    Department of Cardiovascular Surgery, Sureyyapasa Thoracic and Cardiovascular Disease Hospital, Istanbul, Turkey
    Angiology 58:191-5. 2007
    ..001 for each). These results suggest that higher oxidative stress as a result of higher Fe and Cu levels in the AAA, compared with AOD, may be one of the contributing factors in aneurysmal formation as a result of promoted wall erosion...
  13. ncbi request reprint Plasma protein carbonyl and thiol stress before and after laparoscopic gastric banding in morbidly obese patients
    Hafize Uzun
    Istanbul University, Cerrahpasa Medical Faculty, Department of Biochemistry, Turkey
    Obes Surg 17:1367-73. 2007
    ..The aim of this study is to examine the relationship between oxidative plasma protein and thiol stress and weight loss after laparoscopic adjustable gastric banding (LAGB)...
  14. ncbi request reprint The relationship between plasma asymmetrical dimethyl-L-arginine and inflammation and adhesion molecule levels in subjects with normal, impaired, and diabetic glucose tolerance
    Dildar Konukoglu
    Istanbul University, Cerrahpasa Faculty of Medicine, Department of Biochemistry, Istanbul 34303, Turkey
    Metabolism 57:110-5. 2008
    ..A complex interrelation could exist between ADMA and inflammation, and mechanisms involved in endothelial dysfunction are multifactorial at the prediabetic and diabetic state...
  15. ncbi request reprint The effect of prostate cancer and antiandrogenic therapy on lipid peroxidation and antioxidant systems
    Alkan Hacer Iynem
    Department of Biochemistry and Clinical Biochemistry, Cerrahpasa Faculty of Medicine, University of Istanbul, Turkey
    Int Urol Nephrol 36:57-62. 2004
    ..Our results showed that antiandrogenic therapy increased in GST activity, decreased in lipid peroxidation...
  16. ncbi request reprint Plasma leptin and its relationship with lipid peroxidation and nitric oxide in obese female patients with or without hypertension
    Dildar Konukoglu
    Department of Biochemistry, Cerrahpasa Medical Faculty, Istanbul University, Istanbul, Turkey
    Arch Med Res 37:602-6. 2006
    ..We investigated the association of plasma leptin levels with plasma lipid peroxidation and nitric oxide metabolites (NOx) in obese hypertensive atherosclerosis model...
  17. ncbi request reprint Epidural anesthesia may attenuate lipid peroxidation during aorto-femoral surgery
    Lale Yüceyar
    Department of Anesthesiology, Istanbul University Cerrahpasa Medical Faculty, Istanbul, Turkey
    Can J Anaesth 51:465-71. 2004
    ....
  18. doi request reprint Plasma oxidative and inflammatory markers in patients with idiopathic Parkinson's disease
    Gülnur Andican
    Department of Biochemistry, Cerrahpasa Medical Faculty, Istanbul University, Istanbul, Turkey
    Acta Neurol Belg 112:155-9. 2012
    ..Establishing the roles of these pathological processes in PD might be the key to effective therapy at an early stage by antioxidants and/or anti-inflammatory drugs...
  19. ncbi request reprint Association of plasma viscosity with cardiovascular risk factors in obesity: an old marker, a new insight
    Meltem Ercan
    Istanbul University, Cerrahpasa Medical Faculty, Biophysics Department, Istanbul, Turkey
    Clin Hemorheol Microcirc 35:441-6. 2006
    ..We aim to examine the relationship between plasma viscosity and obesity as a cardiovascular disease risk factor in obese and non-obese groups...
  20. ncbi request reprint The effects of renal replacement therapy on plasma, asymmetric dimethylarginine, nitric oxide and C-reactive protein levels
    Halfize Uzun
    Istanbul University, Cerrahpasa Medical Faculty, Department of Biochemistry, Istanbul, Turkey
    Clin Invest Med 31:E1-7. 2008
    ..The aim of the study was to investigate the relationship between renal replacement therapy and endothelial dysfunction...
  21. ncbi request reprint Relationship among plasma secretory phospholipase A2, oxidized low density lipoprotein & paraoxonase activities in hypertensive subjects treated with angiotensin converting enzyme inhibitors
    Dildar Konukoglu
    Istanbul University, Cerrahpasa Faculty of Medicine, Department of Biochemistry, Istanbul, Turkey
    Indian J Med Res 129:390-4. 2009
    ..This study was undertaken to investigate the relationship between oxidative and inflammatory markers in hypertensive patients with or without antihypertensive drug treatment...
  22. ncbi request reprint The effects of exposure of 60Co on the oxidant/antioxidant status among radiation victims
    Mustafa Demir
    Department of Nuclear Medicine, Istanbul University, Istanbul, Turkey
    J Environ Radioact 64:19-25. 2003
    ..It is suggested here that antioxidant supplementation therapy might be effective in preventing the harmful effects of 60Co radiation among radiation victims...
  23. ncbi request reprint Aprotinin ameliorates ischemia/reperfusion injury in a rat hind limb model
    Cengiz Koksal
    Istanbul University, Cerrahpasa Medical Faculty, Department of Cardiovascular Surgery, P O Box 26, Cerrahpasa, 34301, Istanbul, Turkey
    Vascul Pharmacol 41:125-9. 2004
    ..006, p=0.001). These results suggest that aprotinin, a potent anti-inflammatory drug, is more useful than alpha-tocopherol, a powerful antioxidant, for attenuating muscle injury after I/R...
  24. ncbi request reprint Relation of serum vascular endothelial growth factor as an angiogenesis biomarker with nitric oxide & urokinase-type plasminogen activator in breast cancer patients
    Dildar Konukoglu
    Department of Biochemistry, Cerrahpasa Medical Faculty, Istanbul University, Istanbul, Turkey
    Indian J Med Res 125:747-51. 2007
    ..The aim of this study was to investigate the relationship between serum levels of VEGF and NO and u-PA in patients with breast cancer...
  25. ncbi request reprint Serum neurotrophic factor levels in patients with type 2 diabetes mellitus: relationship to metabolic syndrome components
    Sabiha Civelek
    Istanbul University, Cerrahpasa Medical Faculty, Department of Medical Biochemistry, Istanbul, Turkey
    Clin Lab 59:369-74. 2013
    ..The aim of the present study is to examine the levels of neurotrophins in type 2 diabetes mellitus (T2DM) and whether the levels are linked to the components of metabolic syndrome...
  26. ncbi request reprint The effects of cholesterol levels on hemorheological parameters in diabetic patients
    Meltem Ercan
    Department of Biophysics, University of Istanbul, Cerrahpasa Medical Faculty, Istanbul, Turkey
    Clin Hemorheol Microcirc 26:257-63. 2002
    ..001). Our data suggest that elevated plasma cholesterol may impair RBC deformability and increase in blood and plasma viscosity by an additional effect to hyperglycemia in type 2 diabetic patients...
  27. doi request reprint Increased maternal serum and cord blood fibronectin concentrations in preeclampsia are associated with higher placental hyaluronic acid and hydroxyproline content
    Hafize Uzun
    Istanbul University, Cerrahpasa Medical Faculty, Department of Biochemistry, Istanbul, Turkey
    Hypertens Pregnancy 29:153-62. 2010
    ..The purpose of this study was to examine the relationship between maternal serum FN levels and the extracellular matrix molecule contents of placental tissue, such as FN, hyaluronic acid (HA) and hydroxyproline (HP) levels...
  28. ncbi request reprint Is midazolam effective as an antioxidant in preventing reperfusion injury in rat kidney?
    Ugur Erol
    Department of Anesthesiology and Reanimation, University of Marmara, School of Medicine, Istanbul, Turkey
    Int Urol Nephrol 34:121-7. 2002
    ..Right kidneys were histopathologically normal in both groups. We concluded that within this dosage midazolam does not have any antioxidant effect in reperfused rat kidneys following ischemia...
  29. ncbi request reprint Plasma adhesion and inflammation markers: asymmetrical dimethyl-L-arginine and secretory phospholipase A2 concentrations before and after laparoscopic gastric banding in morbidly obese patients
    Dildar Konukoglu
    Istanbul University, Cerrahpasa Medical Faculty, Department of Biochemistry, Istanbul, Turkey
    Obes Surg 17:672-8. 2007
    ..The aim of this study was to examine the relationship between subclinical inflammation and weight loss by laparoscopic adjustable gastric banding (LAGB)...
  30. ncbi request reprint Glutathione and glutathione-related enzymes in colorectal cancer patients
    Eyup Ilker Saygili
    Department of Biochemistry, Cerrahpasa Medical Faculty, University of Istanbul, Istanbul, Turkey
    J Toxicol Environ Health A 66:411-5. 2003
    ..Our results suggest that oxidative stress may play an important role in colorectal tumorigenesis and that these events have no effect on the clinical grading of the colorectal tumor...
  31. doi request reprint The effects of atorvastatin on oxidative stress in L-NAME-treated rats
    Volkan Sozer
    Department of Biochemistry, Yildiz Technical University, Istanbul
    Scand J Clin Lab Invest 73:591-7. 2013
    ..Nω-nitro-l-arginine methyl ester (L-NAME) is a potent synthetic nitric oxide inhibitor, and long-term oral L-NAME treatment is used to induce vascular lesions in experimental animal models...
  32. ncbi request reprint Attenuation of ischemia/reperfusion injury by N-acetylcysteine in a rat hind limb model
    Cengiz Koksal
    Sureyyapasa Thoracic and Cardiovascular Disease Hospital, Departmemnt of Cardiovascular Surgery, Istanbul, Turkey
    J Surg Res 111:236-9. 2003
    ..In present study, we examined the protective effect of NAC in a rat hind limb ischemia/ reperfusion model. Dimethyl-sulfoxide (DMSO), a well-known antioxidant was also tested for comparison...