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Biochanin-A, an isoflavon, showed anti-proliferative and anti-inflammatory activities through the inhibition of iNOS expression, p38-MAPK and ATF-2 phosphorylation and blocking NFκB nuclear translocationLabanyamoy Kole
Syngene International Ltd, Biocon Park, Plot 2 and 3, Bommasandra IV Phase, Jigani Link Road, Bangalore, India
Eur J Pharmacol 653:8-15. 2011..Biochanin-A is important for the prevention of phosphorylation and degradation of IκBα, thereby blocking NF-κB activation, which in turn leads to decreased expression of the iNOS, thus preventing proliferation and inflammation...
