- Establishment of humanized anti-interleukin-5 receptor alpha chain monoclonal antibodies having a potent neutralizing activityMASAMICHI KOIKE
Tokyo Research Laboratories, Kyowa Hakko Kirin, CO, Ltd, Machida shi, Tokyo, Japan
Hum Antibodies 18:17-27. 2009..We also describe the process for humanization of the mouse Mab towards development of a therapeutic MAb. The humanized version of the monoclonal antibody also displayed potent neutralizing activity against IL-5 dependent activities...