A Kocyigit

Summary

Publications

  1. pmc Antimonial therapy induces circulating proinflammatory cytokines in patients with cutaneous leishmaniasis
    Abdurrahim Kocyigit
    Department of Biochemistry, University of Harran Medical School, Sanliurfa 63200, Turkey
    Infect Immun 70:6589-91. 2002
  2. ncbi request reprint Effects of pistachio nuts consumption on plasma lipid profile and oxidative status in healthy volunteers
    A Kocyigit
    Department of Clinical Biochemistry, Medical Faculty, Harran University, Sanliurfa, Turkey
    Nutr Metab Cardiovasc Dis 16:202-9. 2006
  3. ncbi request reprint Erythrocyte antioxidative enzyme activities and lipid peroxidation levels in patients with cutaneous leishmaniasis
    A Kocyigit
    Department of Biochemistry, Medical Faculty, Harran University, 63200 Sanliurfa, Turkey
    Parasite 10:277-81. 2003
  4. ncbi request reprint Increased DNA damage and oxidative stress in patients with cutaneous leishmaniasis
    Abdurrahim Kocyigit
    Harran University, Medical Faculty, Department of Biochemistry, 63200 Sanliurfa, Turkey
    Mutat Res 585:71-8. 2005
  5. ncbi request reprint Effects of tobacco smoking on plasma selenium, zinc, copper and iron concentrations and related antioxidative enzyme activities
    A Kocyigit
    Department of Clinical Biochemistry, Faculty of Medicine, Harran University, 63200 Sanliurfa, Turkey
    Clin Biochem 34:629-33. 2001
  6. ncbi request reprint Effects of antimonial therapy on serum zinc, copper and iron concentrations in patients with cutaneous Leishmaniasis in Turkey
    A Kocyigit
    Department of Biochemistry, Faculty of Harran University, Sanliurfa, Turkey
    J Egypt Soc Parasitol 28:133-42. 1998
  7. ncbi request reprint Oxidative stress and antioxidative status of plasma and erythrocytes in patients with vivax malaria
    O Erel
    Department of Clinical Biochemistry, Faculty of Medicine, Harran University, Sanliurfa Turkey
    Clin Biochem 30:631-9. 1997
  8. ncbi request reprint DNA damage in metabolic syndrome and its association with antioxidative and oxidative measurements
    R Demirbag
    Department of Cardiology, Faculty of Medicine, Harran University, Sanliurfa, Turkey
    Int J Clin Pract 60:1187-93. 2006
  9. ncbi request reprint Alterations in plasma essential trace elements selenium, manganese, zinc, copper, and iron concentrations and the possible role of these elements on oxidative status in patients with childhood asthma
    A Kocyigit
    Department of Biochemistry, Medical Faculty, Harran University, Sanliurfa, Turkey
    Biol Trace Elem Res 97:31-41. 2004
  10. ncbi request reprint Reactive nitrogen and oxygen intermediates in patients with cutaneous leishmaniasis
    O Erel
    Department of Clinical Biochemistry, Harran University, Sanliurfa, Turkey
    Mem Inst Oswaldo Cruz 94:179-83. 1999

Collaborators

Detail Information

Publications46

  1. pmc Antimonial therapy induces circulating proinflammatory cytokines in patients with cutaneous leishmaniasis
    Abdurrahim Kocyigit
    Department of Biochemistry, University of Harran Medical School, Sanliurfa 63200, Turkey
    Infect Immun 70:6589-91. 2002
    ....
  2. ncbi request reprint Effects of pistachio nuts consumption on plasma lipid profile and oxidative status in healthy volunteers
    A Kocyigit
    Department of Clinical Biochemistry, Medical Faculty, Harran University, Sanliurfa, Turkey
    Nutr Metab Cardiovasc Dis 16:202-9. 2006
    ..Effects of pistachio nuts consumption on plasma lipid profile and oxidative status were investigated in healthy volunteers with normal lipid levels...
  3. ncbi request reprint Erythrocyte antioxidative enzyme activities and lipid peroxidation levels in patients with cutaneous leishmaniasis
    A Kocyigit
    Department of Biochemistry, Medical Faculty, Harran University, 63200 Sanliurfa, Turkey
    Parasite 10:277-81. 2003
    ..However, these changes may not only cause the killing of parasite but also may cause oxidative damage in the other cells or tissues...
  4. ncbi request reprint Increased DNA damage and oxidative stress in patients with cutaneous leishmaniasis
    Abdurrahim Kocyigit
    Harran University, Medical Faculty, Department of Biochemistry, 63200 Sanliurfa, Turkey
    Mutat Res 585:71-8. 2005
    ..However, these intermediates not only cause the killing of the parasite but also induce oxidative damage in non-infected cells. Therefore, these patients must be treated urgently to counteract the oxidative DNA damage...
  5. ncbi request reprint Effects of tobacco smoking on plasma selenium, zinc, copper and iron concentrations and related antioxidative enzyme activities
    A Kocyigit
    Department of Clinical Biochemistry, Faculty of Medicine, Harran University, 63200 Sanliurfa, Turkey
    Clin Biochem 34:629-33. 2001
    ..The aim of the study was to investigate whether alterations in antioxidative enzyme activities are dependent on their cofactor concentrations in tobacco smokers...
  6. ncbi request reprint Effects of antimonial therapy on serum zinc, copper and iron concentrations in patients with cutaneous Leishmaniasis in Turkey
    A Kocyigit
    Department of Biochemistry, Faculty of Harran University, Sanliurfa, Turkey
    J Egypt Soc Parasitol 28:133-42. 1998
    ..322, p < 0.05). The findings showed that CL affects the essential trace element content and these changes began to disappear during antimonial therapy...
  7. ncbi request reprint Oxidative stress and antioxidative status of plasma and erythrocytes in patients with vivax malaria
    O Erel
    Department of Clinical Biochemistry, Faculty of Medicine, Harran University, Sanliurfa Turkey
    Clin Biochem 30:631-9. 1997
    ..To investigate the oxidative stress and antioxidative status of plasma and erythrocytes in patients with vivax malaria and healthy persons...
  8. ncbi request reprint DNA damage in metabolic syndrome and its association with antioxidative and oxidative measurements
    R Demirbag
    Department of Cardiology, Faculty of Medicine, Harran University, Sanliurfa, Turkey
    Int J Clin Pract 60:1187-93. 2006
    ..05, for all). DNA damage is increased in patients with MetS. The increase in DNA damage might be occur because of the increase in the imbalance between the production of oxidants and antioxidant defences in subjects with MetS...
  9. ncbi request reprint Alterations in plasma essential trace elements selenium, manganese, zinc, copper, and iron concentrations and the possible role of these elements on oxidative status in patients with childhood asthma
    A Kocyigit
    Department of Biochemistry, Medical Faculty, Harran University, Sanliurfa, Turkey
    Biol Trace Elem Res 97:31-41. 2004
    ..These observations suggest that increased Fe and decreased Se concentrations in patients with childhood asthma may be responsible for the oxidant/antioxidant imbalance...
  10. ncbi request reprint Reactive nitrogen and oxygen intermediates in patients with cutaneous leishmaniasis
    O Erel
    Department of Clinical Biochemistry, Harran University, Sanliurfa, Turkey
    Mem Inst Oswaldo Cruz 94:179-83. 1999
    ..These alterations in ROI enable nitric oxide (NO) to amplify its leishmanicidal effect. The determination of ROI and RNI in patients with CL may be a useful tool to evaluate effector mechanisms of NO and clinical manifestations...
  11. ncbi request reprint Efficacy of cryotherapy and intralesional pentostam in treatment of cutaneous leishmaniasis
    M S Gurei
    Department of Dermatology, Medical School, Harran University, Sanliurfa, Turkey
    J Egypt Soc Parasitol 30:169-76. 2000
    ..They showed no severe side effects and no significant changes in laboratory values. It is suggested that cryotherapy is an alternative to intralesional pentostam injection...
  12. ncbi request reprint Synovial fluid and plasma selenium, copper, zinc, and iron concentrations in patients with rheumatoid arthritis and osteoarthritis
    M Yazar
    Department of Orthopaedic Surgery, Harran University, Medical Faculty, 63200 Sanliurfa Turkey
    Biol Trace Elem Res 106:123-32. 2005
    ..These alterations in trace element concentrations in inflammatory RA might be a result of the changes of the immunoregulatory cytokines...
  13. ncbi request reprint Oxidative and antioxidative balance in patients of migraine
    R Alp
    Department of Neurology, Faculty of Medicine, University of Kafkas, Kars, Turkey
    Eur Rev Med Pharmacol Sci 14:877-82. 2010
    ..To the best of our knowledge, this is the first study investigating oxidant and antioxidant status of patients having migraine without aura (MWoA) and comparing them with those of age and sex matched healthy controls (CG)...
  14. ncbi request reprint Evaluation of systemic oxidative status and mononuclear leukocytes DNA damage in children with caustic esophageal stricture
    M Kaya
    Department of Pediatric Surgery, Medical Faculty, Harran University, Sanliurfa, Turkey
    Dis Esophagus 19:280-4. 2006
    ..On the other hand, these results support that patients with ES may benefit from antioxidant treatment...
  15. ncbi request reprint Relationship among manganese, arginase, and nitric oxide in childhood asthma
    A Kocyigit
    Department of Biochemistry, Medical Faculty, Harran University, 63200 Sanliurfa, Turkey
    Biol Trace Elem Res 102:11-8. 2004
    ..These data indicate that the lower concentration of Mn could cause lower arginase activity and this could also upregulate NO production by increasing l-arginine content in patients with childhood asthma...
  16. ncbi request reprint The association of circulating leptin level with peripheral DNA damage in hemodialysis subjects
    Mehmet Horoz
    Harran University School of Medicine, Department of Internal Medicine, Sanliurfa, Turkey
    Clin Biochem 39:918-22. 2006
    ..Thus, in the present study, we aimed at finding out if there is any relationship between serum leptin level and peripheral DNA damage in hemodialysis subjects...
  17. ncbi request reprint Is the arginine-nitric oxide pathway involved in the pathogenesis of schizophrenia?
    Medaim Yanik
    Department of Psychiatry, Faculty of Medicine, University of Harran, Sanliurfa, Turkey
    Neuropsychobiology 47:61-5. 2003
    ..Our results suggest that the arginine-NO pathway is involved in the pathogenesis of schizophrenia...
  18. ncbi request reprint No increase in sperm DNA damage and seminal oxidative stress in patients with idiopathic infertility
    Fatma Ferda Verit
    Department of Obstetrics and Gynecology, Harran University Medical School, Arastirma ve Uygulama Hastanesi, Sanliurfa, 63100, Turkey
    Arch Gynecol Obstet 274:339-44. 2006
    ..We think that the pathophysiology of idiopathic infertility cannot be explained by sperm DNA damage or seminal oxidative stress...
  19. ncbi request reprint Lymphocyte DNA damage and oxidative stress in patients with iron deficiency anemia
    Mehmet Aslan
    Harran University, School of Medicine, Department of Internal Medicine, Sanliurfa, Turkey
    Mutat Res 601:144-9. 2006
    ..The relationships of oxidative stress and DNA damage with the severity of anemia suggest that both oxidative stress and DNA damage may, in part, have a role in the pathogenesis of IDA...
  20. ncbi request reprint Associations among plasma selenium, zinc, copper, and iron concentrations and immunoregulatory cytokine levels in patients with cutaneous leishmaniasis
    Abdurrahim Kocyigit
    Department of Biochemistry, Medical Faculty, Harran University, 63200 Sanliurfa, Turkey
    Biol Trace Elem Res 90:47-55. 2002
    ..These changes may not be a result of a specific deficiency from dietary inadequacies or imbalances, but, probably, a result of a part of the defense strategies of an organism that is regulated by immunoregulatory cytokines...
  21. ncbi request reprint Increased DNA damage and oxidative stress in patients with rheumatoid arthritis
    Ozlem Altindag
    Harran University, Medical Faculty, Research Hospital, Department of Physical Medicine and Rehabilitation, Tr 63100 Sanliurfa, Turkey
    Clin Biochem 40:167-71. 2007
    ..The aim of the study was to investigate the peripheral DNA damage, total antioxidant status (TAS), and total oxidative status (TOS) in patients with RA...
  22. ncbi request reprint Relationship between total oxidant status and severity of diabetic nephropathy in type 2 diabetic patients
    Mehmet Aslan
    Department of Endocrinology, Faculty of Medicine, Harran University, Sanliurfa, Turkey
    Nutr Metab Cardiovasc Dis 17:734-40. 2007
    ..The objective of this study was to investigate possible associations between total oxidant status (TOS) and the severity of diabetic nephropathy in type 2 diabetic patients by using a novel automated measurement method...
  23. ncbi request reprint Lymphocyte DNA damage is associated with increased aortic intima-media thickness
    Mustafa Gur
    Harran University, Faculty of Medicine, Department of Cardiology, Sanliurfa, Turkey
    Mutat Res 617:111-8. 2007
    ..To investigate whether there is an association between lymphocyte DNA damage and aortic intima-media thickness (IMT)...
  24. ncbi request reprint Plasma total antioxidant capacity, lipid peroxidation, and erythrocyte antioxidant enzyme activities in patients with rheumatoid arthritis and osteoarthritis
    Sezgin Sarban
    Department of Orthopaedic Surgery, Harran University, Medical Faculty, 63200 Sanliurfa, Turkey
    Clin Biochem 38:981-6. 2005
    ..The aim of the present study was to investigate the total antioxidant capacity (TAC), levels of lipid peroxidation (LPO), and antioxidant enzyme activities in patients with rheumatoid arthritis (RA) and osteoarthritis (OA)...
  25. ncbi request reprint Effect of coronary angiography on oxidative DNA damage observed in circulating lymphocytes
    Recep Demirbag
    Department of Cardiology, Harran University, Faculty of Medicine, Sanliurfa, Turkey
    Angiology 58:141-7. 2007
    ..Our findings demonstrate that increased oxidative DNA damage in undergoing coronary angiography might be dependent on the severity of coronary artery disease and age, rather than on contrast media and radiation exposure time...
  26. ncbi request reprint PON1 activity and total oxidant status in patients with active pulmonary tuberculosis
    Sahbettin Selek
    Department of Biochemistry, School of Medicine, Harran University, Sanliurfa, Turkey
    Clin Biochem 41:140-4. 2008
    ..The aim of this study was to the investigate effect of tuberculosis infection on paraoxonase-1 (PON1) activity and oxidative status in patients with pulmonary tuberculosis (PTB)...
  27. doi request reprint Phototherapy causes DNA damage in peripheral mononuclear leukocytes in term infants
    Ali Aycicek
    Pediatrics Department, Medical Faculty, Harran University, Sanliurfa, Turkey
    J Pediatr (Rio J) 84:141-6. 2008
    ..Our aim was to determine whether endogenous mononuclear leukocyte DNA strand is a target of phototherapy...
  28. doi request reprint Phototherapy increases DNA damage in lymphocytes of hyperbilirubinemic neonates
    Mustafa Mansur Tatli
    Division of Neonatology, Department of Pediatrics, Fatih University School of Medicine, Ankara, Turkey
    Mutat Res 654:93-5. 2008
    ..It remains to be seen whether the genotoxic effect observed in the present study can cause any long-term health effect in phototherapy-treated infants in later life...
  29. ncbi request reprint Relationship between levels of DNA damage in lymphocytes and histopathological severity of chronic hepatitis C and various clinical forms of hepatitis B
    Cengiz Bolukbas
    Department of Internal Medicine, Gastroenterology Division, Harran University, Medical Faculty, Sanliurfa, Turkey
    J Gastroenterol Hepatol 21:610-6. 2006
    ....
  30. ncbi request reprint Breast milk provides better antioxidant power than does formula
    Ali Aycicek
    Department of Pediatrics, Children s Hospital at Sanliurfa, Sanliurfa, Turkey
    Nutrition 22:616-9. 2006
    ..We examined the effect of breast milk on plasma total antioxidant capacity (TAC), total peroxide (TP), and oxidative stress index (OSI), which are biomarkers of oxidative status...
  31. ncbi request reprint High frequency of maternal vitamin B12 deficiency as an important cause of infantile vitamin B12 deficiency in Sanliurfa province of Turkey
    Ahmet Koc
    Research Hospital, Dept of Pediatric Hematology, Harran University Faculty of Medicine Research Hospital, 63 100 Sanliurfa, Turkey
    Eur J Nutr 45:291-7. 2006
    ..It is well known that infants born with deficient vitamin B12 storage have increased the risk of vitamin B12 deficiency. Vitamin B12 deficiency is more prevalent in infancy in Sanliurfa province (at the southeast region of Turkey)...
  32. ncbi request reprint Intranasal 17beta-estradiol treatment and Vitamin B12, folate and homocysteine in menopause
    Muge Harma
    Department of Obstetrics and Gynecology, University of Harran, Medical School, Sanliurfa, Turkey
    Maturitas 50:353-8. 2005
    ..This study assessed the effect of intranasal administration of 17beta-estradiol (Aerodiol) on plasma levels of homocysteine, Vitamin B12 and folate in postmenopausal women...
  33. ncbi request reprint Increased DNA damage in patients with complete hydatidiform mole
    Mehmet Harma
    Department of Obstetrics and Gynecology, University of Harran, Medical School, Sanliurfa, Turkey
    Mutat Res 583:49-54. 2005
    ..However, the nature of this link, and whether it is direct or indirect, remains to be explored...
  34. ncbi request reprint Lymphocyte DNA damage in patients with acute coronary syndrome and its relationship with severity of acute coronary syndrome
    Recep Demirbag
    Harran University, Faculty of Medicine, Department of Cardiology, Sanliurfa, Turkey
    Mutat Res 578:298-307. 2005
    ..The aim of this study was to investigate the association between lymphocyte DNA damage and acute coronary syndromes (ACS)...
  35. ncbi request reprint Comparison of protein carbonyl and total plasma thiol concentrations in patients with complete hydatidiform mole with those in healthy pregnant women
    Mehmet Harma
    Department of Obstetrics and Gynecology, University of Harran Medical School, Sanliurfa, Turkey
    Acta Obstet Gynecol Scand 83:857-60. 2004
    ..Normal pregnant women are known to have increased oxidative stress and lipid peroxidation (which can be estimated by protein carbonyl concentration) but offsetting antioxidant protection (of which plasma thiols are an important component)...
  36. ncbi request reprint Increased oxidative stress in infants exposed to passive smoking
    Ali Aycicek
    Paediatrics Department, Children s Hospital of Sanliurfa, Turkey
    Eur J Pediatr 164:775-8. 2005
    ..01). We conclude that passive smoking has a negative impact on numerous parts of the antioxidant defence system in infants, and exposes them to potent oxidative stress...
  37. ncbi request reprint Relationship between synovial fluid and plasma manganese, arginase, and nitric oxide in patients with rheumatoid arthritis
    Sezgin Sarban
    Department of Orthopaedic Surgery, Harran University, Medical Faculty, Sanliurfa, Turkey
    Biol Trace Elem Res 115:97-106. 2007
    ..Our results indicate that the lower concentration of synovial fluid Mn could cause lower arginase activity and this could also upregulate NO production by increasing L-arginine content in patients with RA...
  38. ncbi request reprint Serum levels of folate, vitamin B12 and homocysteine in complete hydatidiform mole
    Muge Harma
    Department of Gynecology and Obstetrics, Faculty of Medicine, University of Harran, Sanliurfa, Turkey
    J Reprod Med 49:285-8. 2004
    ..To investigate the association, if any, between serum concentrations of folate, vitamin B12 and homocysteine in complete hydatiform mole (CHM)...
  39. ncbi request reprint Plasma manganese, selenium, zinc, copper, and iron concentrations in patients with schizophrenia
    Medaim Yanik
    Department of Psychiatry, Faculty of Medicine, University of Harran, Sanliurfa, Turkey
    Biol Trace Elem Res 98:109-17. 2004
    ..However, findings from trace element levels in schizophrenia show a variety of results that are difficult to interpret...
  40. ncbi request reprint Increased DNA damage in patients with chronic obstructive pulmonary disease who had once smoked or been exposed to biomass
    Erkan Ceylan
    Department of Chest Disease, Medical Faculty, Harran University, Sanliurfa, Turkey
    Respir Med 100:1270-6. 2006
    ....
  41. ncbi request reprint Decreased total antioxidant capacity and increased oxidative stress in passive smoker infants and their mothers
    Ali Aycicek
    Department of Pediatrics, Children s Hospital at Sanliurfa, Sanliurfa, Turkey
    Pediatr Int 47:635-9. 2005
    ..The purpose of the study was to study the effect of passive cigarette smoking on oxidative and antioxidative status of plasma in passive smoker infants and their mothers and to compare with those of non-smokers...
  42. ncbi request reprint Assessment of peripheral DNA damage by alkaline comet assay in maintenance hemodialysis subjects with hepatitis C infection
    Mehmet Horoz
    Harran University, School of Medicine, Department of Internal Medicine, Sanliurfa, Turkey
    Mutat Res 596:137-42. 2006
    ..However, in hemodialysis subjects, hepatitis C infection does not cause significant additional increase in DNA damage level, and it may be partly due to protective effect of hemodialysis on hepatitis C infection...
  43. ncbi request reprint Association of increased total antioxidant capacity and anovulation in nonobese infertile patients with clomiphene citrate-resistant polycystic ovary syndrome
    Fatma Ferda Verit
    Department of Obstetrics and Gynecology, Faculty of Medicine, Harran University, Sanliurfa, Turkey
    Fertil Steril 88:418-24. 2007
    ..To investigate whether total antioxidant capacity (TAC) could predict the response to ovulation induction to clomiphene citrate (CC) in nonobese women with polycystic ovary syndrome...
  44. ncbi request reprint Serum levels of zinc and copper in hydatidiform mole
    Mehmet Harma
    Department of Obstetrics and Gynecology, Faculty of Medicine, University of Harran, Sanliurfa, Turkey
    Arch Gynecol Obstet 271:304-6. 2005
    ..The aim of this study was to identify any association between serum levels of trace elements zinc and copper and development of hydatidiform mole...
  45. ncbi request reprint Relationship between DNA damage, total antioxidant capacity and coronary artery disease
    Recep Demirbag
    Harran University, Faculty of Medicine, Department of Cardiology, PK 112, 63200 Sanliurfa, Turkey
    Mutat Res 570:197-203. 2005
    ..However, little is known about association of DNA damage with total antioxidant capacity (TAC) and CAD. The aim of this study is to evaluate the relationship between DNA damage, TAC and CAD...
  46. ncbi request reprint Essential trace elements selenium, zinc, copper, and iron concentrations and their related acute-phase proteins in patients with vivax malaria
    Adnan Seyrek
    Department of Microbiology, Medical Faculty, Firat University, Elazig, Turkey
    Biol Trace Elem Res 106:107-15. 2005
    ....