Copper deficiency with increased hematogones mimicking refractory anemia with excess blastsEbru Koca
Hematology Division, Department of Internal Medicine, Hacettepe University Medical School, Ankara, Turkey
Leuk Res 32:495-9. 2008
..An evaluation to identify the cause of copper deficiency, revealed intestinal amyloidosis. Based on our experience we recommend serum copper determination in the diagnostic workup of MDS in patients with comorbidities...
Renin-angiotensin system expression in the K562 human erythroleukaemic cell lineEbru Koca
Hacettepe University Medical School, Departments of Internal Medicine and Haematology, Ankara, Turkey
J Renin Angiotensin Aldosterone Syst 8:145-7. 2007
..Therefore, K562 human erythroleukaemia cell line may serve as an in vitro model to elucidate the role of RAS in leukaemia and to test the effects of RAS-affecting drugs on leukaemic cellular proliferation...
Angiotensin-converting enzyme expression of the lymphoma-associated macrophages in the lymph nodes of Hodgkin's diseaseEbru Koca
Department of Hematology, Hacettepe University Medical School, Sihhiye, Ankara, Turkey
J Natl Med Assoc 99:1243-4, 1246-7. 2007
..We assessed ACE expression in the neoplastic lymph node microenvironment of Hodgkin's lymphoma (HL), particularly in macrophages and in nonneoplastic lymphoid tissue...
Overexpression of the local bone marrow renin-angiotensin system in acute myeloid leukemiaYavuz Beyazit
Department of Internal Medicine, Hacettepe University Medical School, Ankara, Turkey
J Natl Med Assoc 99:57-63. 2007
..The aim of this study is therefore to search those major RAS components simultaneously in the leukemic blast cells taken from the bone marrow of patients with acute myeloid leukemia (AML)...
Soluble platelet glycoprotein V in distinct disease states of pathological thrombopoiesisKadir Acar
Department of Hematology, Selcuk University Meram Medical School, Konya, Turkey
J Natl Med Assoc 100:86-90. 2008
..Therefore, glycoprotein V system may serve to activate residual platelets in thrombocytopenia regardless of its origin is either ITP or AA...
Unchanged global fibrinolytic capacity during the course of hematopoietic stem cell transplantationSalih Aksu
Department of Hematology, Hacettepe University Medical School, Sihhiye, Ankara, Turkey
Blood Coagul Fibrinolysis 17:47-51. 2006
..Further studies in larger HSCT populations are warranted to better understand the implications of these findings...
Unusual extramedullary recurrences and breast relapse despite hepatic GVHD after allografting in Ph+-ALLEbru Koca
Hacettepe University, Division of Hematology, Department of Internal Medicine, Ankara, Turkey
Hematology 11:105-7. 2006
....
Changing clinical manifestations of a T-peripheral lymphoma: from hypereosinophilic syndrome to questionable Kimura's disease resulting in parotid massYavuz Beyazit
Department of Internal Medicine, Hacettepe University Medical School, Ankara, Turkey
Leuk Lymphoma 47:357-60. 2006
..This unique clinical presentation pattern of the patient may represent the distinct pathobiological progression of a clonal neoplastic lymphoproliferative disorder...
Endogenous thrombopoietin levels during the clinical management of acute myeloid leukaemiaCan Gonen
Department of Internal Medicine, Hacettepe University School of Medicine, Sihhiye, 06100 Ankara, Turkey
Platelets 16:31-7. 2005
..TPO levels in distinct AML disease states may explain the unsuccessful recombinant TPO trials and could help to design better strategies for 'pharmacological stimulation of thrombopoiesis' in AML...