Gary T C Ko

Summary

Publications

  1. ncbi request reprint Blood pressure reduction and tolerability of amlodipine versus nifedipine retard in Chinese patients with type 2 diabetes mellitus and hypertension: a randomized 1-year clinical trial
    G T Ko
    Department of Medicine, Alice Ho Miu Ling Nethersole Hospital, Tai Po, Hong Kong
    Int J Clin Pharmacol Ther 39:331-5. 2001
  2. ncbi request reprint Gastrointestinal symptoms in Chinese patients with Type 2 diabetes mellitus
    G T Ko
    Department of Medicine and Therapeutics, Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories
    Diabet Med 16:670-4. 1999
  3. ncbi request reprint Effects of body mass index, plasma glucose and cholesterol levels on isolated systolic hypertension
    Gary T C Ko
    Department of Medicine, Alice Ho Nethersole Hospital, Tai Po, Hong Kong
    Int J Cardiol 101:429-33. 2005
  4. ncbi request reprint Short-term effects after a 3-month aerobic or anaerobic exercise programme in Hong Kong Chinese
    G T C Ko
    Department of Medicine, Alice HML Nethersole Hospital, Hong Kong
    Diabetes Nutr Metab 17:124-7. 2004
  5. ncbi request reprint Effects of obesity on the conversion from normal glucose tolerance to diabetes in Hong Kong Chinese
    Gary T C Ko
    Department of Medicine, Alice Ho Miu Ling Nethersole Hospital, 11, Chuen On Road, Tai Po, NT, Hong Kong
    Obes Res 12:889-95. 2004
  6. ncbi request reprint Dexfenfluramine and heart-valve regurgitation in Chinese patients with type 2 diabetes
    G T C Ko
    Department of Medicine, Alice Ho Miu Ling Nethersole Hospital, Tai Po, Hong Kong
    Hong Kong Med J 9:243-6. 2003
  7. ncbi request reprint Restoration of nocturnal dip in blood pressure is associated with improvement in left ventricular ejection fraction. A 1-year clinical study comparing the effects of amlodipine and nifedipine retard on ambulatory blood pressure and left ventricular systol
    Gary T C Ko
    Department of Medicine, Alice Ho Miu Ling Nethersole Hospital, 11, Chuen On Road, Hong Kong, Tai Po, China
    Int J Cardiol 89:159-66. 2003
  8. ncbi request reprint Glycaemic control and obesity are the major determinants of diabetic dyslipidaemia in Hong Kong Chinese
    G T Ko
    Department of Medicine, Alice Ho Miu Ling Nethersole Hospital, 11 Chuen On Road, Tai Po, Hong Kong, ROC
    Diabetes Metab 27:637-44. 2001
  9. ncbi request reprint Change of glycaemic status in Chinese subjects with impaired fasting glycaemia
    G T Ko
    Department of Medicine, Alice Ho Miu Ling Nethersole Hospital, Tai Po, NT, Hong Kong
    Diabet Med 18:745-8. 2001
  10. ncbi request reprint Obesity, insulin resistance and isolated low high-density-lipoprotein cholesterol in Chinese subjects
    G T Ko
    Department of Medicine, Alice Ho Miu Ling Nethersole Hospital, Tai Po, NT, Hong Kong
    Diabet Med 18:663-6. 2001

Collaborators

Detail Information

Publications70

  1. ncbi request reprint Blood pressure reduction and tolerability of amlodipine versus nifedipine retard in Chinese patients with type 2 diabetes mellitus and hypertension: a randomized 1-year clinical trial
    G T Ko
    Department of Medicine, Alice Ho Miu Ling Nethersole Hospital, Tai Po, Hong Kong
    Int J Clin Pharmacol Ther 39:331-5. 2001
    ..In this 1-year clinical study, we compared the efficacy and tolerability of amlodipine and nifedipine retard in 64 Chinese Type 2 diabetic patients with hypertension...
  2. ncbi request reprint Gastrointestinal symptoms in Chinese patients with Type 2 diabetes mellitus
    G T Ko
    Department of Medicine and Therapeutics, Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories
    Diabet Med 16:670-4. 1999
    ..To examine and compare gastrointestinal (GI) symptoms in Hong Kong Chinese Type 2 diabetic outpatients and non-diabetic control subjects...
  3. ncbi request reprint Effects of body mass index, plasma glucose and cholesterol levels on isolated systolic hypertension
    Gary T C Ko
    Department of Medicine, Alice Ho Nethersole Hospital, Tai Po, Hong Kong
    Int J Cardiol 101:429-33. 2005
    ..Age, obesity, lipid and duration of diabetes were independent associated with ISH. These findings suggest that control of body weight and metabolic profile might have beneficial effects on ISH...
  4. ncbi request reprint Short-term effects after a 3-month aerobic or anaerobic exercise programme in Hong Kong Chinese
    G T C Ko
    Department of Medicine, Alice HML Nethersole Hospital, Hong Kong
    Diabetes Nutr Metab 17:124-7. 2004
    ..Plasma insulin level was, otherwise, similar before and after exercise in both groups. This is compatible with a blunted insulin hormonal response to endurance exercise and an improved tissue sensitivity to insulin...
  5. ncbi request reprint Effects of obesity on the conversion from normal glucose tolerance to diabetes in Hong Kong Chinese
    Gary T C Ko
    Department of Medicine, Alice Ho Miu Ling Nethersole Hospital, 11, Chuen On Road, Tai Po, NT, Hong Kong
    Obes Res 12:889-95. 2004
    ..To assess the effects of BMI on progression to diabetes in Hong Kong Chinese and to analyze the optimal cutoff for overweight and obesity in Hong Kong Chinese...
  6. ncbi request reprint Dexfenfluramine and heart-valve regurgitation in Chinese patients with type 2 diabetes
    G T C Ko
    Department of Medicine, Alice Ho Miu Ling Nethersole Hospital, Tai Po, Hong Kong
    Hong Kong Med J 9:243-6. 2003
    ..To assess whether valvular lesions are associated with the use of dexfenfluramine in Chinese patients with type 2 diabetes...
  7. ncbi request reprint Restoration of nocturnal dip in blood pressure is associated with improvement in left ventricular ejection fraction. A 1-year clinical study comparing the effects of amlodipine and nifedipine retard on ambulatory blood pressure and left ventricular systol
    Gary T C Ko
    Department of Medicine, Alice Ho Miu Ling Nethersole Hospital, 11, Chuen On Road, Hong Kong, Tai Po, China
    Int J Cardiol 89:159-66. 2003
    ..The clinical significance and underlying mechanisms require further studies...
  8. ncbi request reprint Glycaemic control and obesity are the major determinants of diabetic dyslipidaemia in Hong Kong Chinese
    G T Ko
    Department of Medicine, Alice Ho Miu Ling Nethersole Hospital, 11 Chuen On Road, Tai Po, Hong Kong, ROC
    Diabetes Metab 27:637-44. 2001
    ..Dyslipidaemia plays a major role in the increased mortality in diabetes. Our aim was to address the quantitative abnormalities and determinants for lipid abnormalities in Chinese Type 2 diabetic patients...
  9. ncbi request reprint Change of glycaemic status in Chinese subjects with impaired fasting glycaemia
    G T Ko
    Department of Medicine, Alice Ho Miu Ling Nethersole Hospital, Tai Po, NT, Hong Kong
    Diabet Med 18:745-8. 2001
    ..To examine the risk of progression to diabetes in Chinese subjects with impaired fasting glycaemia (IFG) or normal fasting glucose (NFG)...
  10. ncbi request reprint Obesity, insulin resistance and isolated low high-density-lipoprotein cholesterol in Chinese subjects
    G T Ko
    Department of Medicine, Alice Ho Miu Ling Nethersole Hospital, Tai Po, NT, Hong Kong
    Diabet Med 18:663-6. 2001
    ..2 mmol/l) was similar to those with hypercholesterolaemia. We examined the prevalence of isolated low HDL-C in Hong Kong Chinese and its relationship with insulin resistance and triglyceride (TG) level...
  11. ncbi request reprint Body mass index profile in Hong Kong Chinese adults
    G T Ko
    Alice Ho Miu Ling Nethersole Hospital, 11 Chuen On Road, Tai Po, Hong Kong, SAR China
    Ann Acad Med Singapore 30:393-6. 2001
    ..Obesity has now become an epidemic with increasing prevalence in most parts of the world. However, information on the problem of obesity in Asians is limited...
  12. ncbi request reprint Prediction of hypertension, diabetes, dyslipidaemia or albuminuria using simple anthropometric indexes in Hong Kong Chinese
    G T Ko
    Department of Medicine and Therapeutics, Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong
    Int J Obes Relat Metab Disord 23:1136-42. 1999
    ..In this analysis, we aimed to assess which anthropometric cutoff values are best at predicting the likelihood of diabetes, hypertension, dyslipidaemia and albuminuria in Hong Kong Chinese...
  13. ncbi request reprint Outcomes of screening for diabetes in high-risk Hong Kong Chinese subjects
    G T Ko
    Department of Medicine and Therapeutics, The Chinese University of Hong Kong, The Prince of Wales Hospital, Shatin
    Diabetes Care 23:1290-4. 2000
    ..To examine the significance of individual risk factors on the development of diabetes in subjects who underwent screening for diabetes...
  14. ncbi request reprint Hyperfibrinogenaemia did not improve after treating hyperglycaemia in Chinese type 2 diabetic patients
    G T Ko
    Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, NT
    Ann Clin Biochem 37:655-61. 2000
    ..282, P = 0.011) was identified as the only independent variable that predicted the changes in the fibrinogen concentrations. Improved glycaemic control was not accompanied by a reduction in plasma fibrinogen concentration...
  15. ncbi request reprint Effects of a structured health education programme by a diabetic education nurse on cardiovascular risk factors in Chinese Type 2 diabetic patients: a 1-year prospective randomized study
    G T C Ko
    Department of Medicine, AH Nethersole Hospital, Tai Po, Hong Kong
    Diabet Med 21:1274-9. 2004
    ..To assess the effect of regular diabetic health education on cardiovascular risk factors in Chinese Type 2 diabetic patients...
  16. ncbi request reprint Cardiovascular disease in chinese type 2 diabetic women is associated with a prolonged QTc interval
    G T Ko
    Department of Medicine and Therapeutics, The Chinese University of Hong Kong, The Prince of Wales Hospital, N T, Shatin, Hong Kong
    Int J Cardiol 76:75-80. 2000
    ..Age, systolic blood pressure and female gender are independently correlated to QTc interval...
  17. ncbi request reprint Combined use of fasting plasma glucose and HbA1c predicts the progression to diabetes in Chinese subjects
    G T Ko
    Department of Medicine, Alice Ho Miu Ling Nethersole Hospital, Tai Po, Hong Kong, China
    Diabetes Care 23:1770-3. 2000
    ..In this article, we followed up on 208 nondiabetic subjects and examined their rates of progression to diabetes. We analyzed their likelihood of becoming diabetic according to their baseline FPG and HbA1c concentrations...
  18. ncbi request reprint Lower BMI cut-off value to define obesity in Hong Kong Chinese: an analysis based on body fat assessment by bioelectrical impedance
    G T Ko
    Department of Medicine, Alice Ho Miu Ling Nethersole Hospital, 11, Chuen On Road, Tai Po, Hong Kong
    Br J Nutr 85:239-42. 2001
    ..We suggest a BMI of 23 kg/m(2) and 26 kg/m(2) as the cut-off values to define overweight and obesity respectively in Hong Kong Chinese...
  19. pmc Smoking and diabetes in Chinese men
    G T Ko
    Department of Medicine and Therapeutics, Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, NT, Hong Kong
    Postgrad Med J 77:240-3. 2001
    ..7. The prevalence of smoking in Hong Kong Chinese women is low and its association with diabetes is inconclusive...
  20. doi request reprint Development and validation of a total coronary heart disease risk score in type 2 diabetes mellitus
    Xilin Yang
    Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Hong Kong, SAR, China
    Am J Cardiol 101:596-601. 2008
    ..External validations are required in other Chinese populations...
  21. doi request reprint White blood cell count and renin-angiotensin system inhibitors for the risk of cancer in type 2 diabetes
    Xilin Yang
    Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Shatin, Hong Kong, SAR, China
    Diabetes Res Clin Pract 87:117-25. 2010
    ..We hypothesize that RAS inhibitors may reduce cancer risk associated with high WBC in type 2 diabetes mellitus (T2DM)...
  22. doi request reprint Associations of overweight with insulin resistance, beta-cell function and inflammatory markers in Chinese adolescents
    Alice P S Kong
    Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Hong Kong SAR, China
    Pediatr Diabetes 9:488-95. 2008
    ..In this study, we analysed the clinical and biochemical factors associated with overweight and obesity in Chinese adolescents...
  23. doi request reprint Use of anti-diabetic drugs and glycaemic control in type 2 diabetes-tThe Hong Kong Diabetes Registry
    Peter C Y Tong
    Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Hong Kong SAR, China
    Diabetes Res Clin Pract 82:346-52. 2008
    ..Early intensification of therapy and system improvement are needed to enhance the effectiveness of these drugs in clinical practice...
  24. doi request reprint Use of thiazolidinedione and cancer risk in Type 2 diabetes: the Hong Kong diabetes registry
    Xilin Yang
    Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Hong Kong, China
    Diabetes Res Clin Pract 97:e13-7. 2012
    ..During a median follow-up of 4.93 years, 270 patients developed cancer. Use of TZDs was associated with reduced risk of cancer in a dose-response manner in multivariable analysis...
  25. ncbi request reprint Effectiveness of a lifestyle modification programme in weight maintenance in obese subjects after cessation of treatment with Orlistat
    Jean Woo
    Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Hong Kong, China
    J Eval Clin Pract 13:853-9. 2007
    ..To examine the efficacy of a lifestyle modification programme in weight maintenance for obese subjects after cessation of treatment with Orlistat...
  26. ncbi request reprint The effect of orlistat-induced weight loss, without concomitant hypocaloric diet, on cardiovascular risk factors and insulin sensitivity in young obese Chinese subjects with or without type 2 diabetes
    Peter C Y Tong
    Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong
    Arch Intern Med 162:2428-35. 2002
    ..We examined the weight-losing effect of orlistat treatment on insulin sensitivity and cardiovascular risk factors in a group of severely obese young Chinese patients with or without type 2 diabetes mellitus...
  27. ncbi request reprint Effects of treatment targets on subsequent cardiovascular events in Chinese patients with type 2 diabetes
    Alice P S Kong
    Li Ka Shing Institute of Health Sciences, Hong Kong, China
    Diabetes Care 30:953-9. 2007
    ..We examined risk associations between achieving treatment targets for glycemia, blood pressure and lipid control, and other risk factors on subsequent cardiovascular events in Chinese patients with type 2 diabetes...
  28. doi request reprint Independent associations of alanine aminotransferase (ALT) levels with cardiovascular risk factor clustering in Chinese adolescents
    Alice P S Kong
    Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, N T, Hong Kong SAR, China
    J Hepatol 49:115-22. 2008
    ..To establish the prevalence of elevated serum alanine aminotransferase (ALT) concentrations in Chinese adolescents, and to explore the nature of associations amongst ALT, obesity and cardiovascular risk factors...
  29. pmc Additive interaction of hyperglycemia and albuminuria on risk of ischemic stroke in type 2 diabetes: Hong Kong Diabetes Registry
    Xilin Yang
    Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Hong Kong SAR, China
    Diabetes Care 31:2294-300. 2008
    ..The study aims to test whether biological interaction between hyperglycemia and albuminuria can explain the inconsistent findings from epidemiological studies and clinical trials about effects of hyperglycemia on stroke in type 2 diabetes...
  30. doi request reprint Development and validation of an all-cause mortality risk score in type 2 diabetes
    Xilin Yang
    Department of Medicine and Therapeutics, Prince of Wales Hospital, Chinese University of Hong Kong, Shatin, Hong Kong SAR, China
    Arch Intern Med 168:451-7. 2008
    ..Diabetes reduces life expectancy by 10 to 12 years, but whether death can be predicted in type 2 diabetes mellitus remains uncertain...
  31. ncbi request reprint Effect of angiotensin-converting enzyme inhibition on survival in 3773 Chinese type 2 diabetic patients
    Wing Yee So
    Department of Medicine and Therapeutics, Prince of Wales Hospital, Chinese University of Hong Kong, Shatin, Hong Kong
    Hypertension 44:294-9. 2004
    ..The effects of ACE inhibitors in type 2 diabetic patients with normoalbuminuria require further evaluation...
  32. pmc Additive interaction between the renin-angiotensin system and lipid metabolism for cancer in type 2 diabetes
    Xilin Yang
    Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong SAR, China
    Diabetes 58:1518-25. 2009
    ..The aim of this study was to explore interactions between these two systems in mediating cancer risk in type 2 diabetes...
  33. ncbi request reprint Effects of protocol-driven care versus usual outpatient clinic care on survival rates in patients with type 2 diabetes
    Wing Yee So
    Department of Medicine and Therapeutics, The Chinese University of Hong Kong, The Prince of Wales Hospital, 30 32 Ngan Shing Street Shatin, NT, Hong Kong
    Am J Manag Care 9:606-15. 2003
    ..To determine whether clinical outcomes in patients with type 2 diabetes were improved by protocol-driven care in a Diabetes Centre compared with usual outpatient care...
  34. pmc Effect of interactions between C peptide levels and insulin treatment on clinical outcomes among patients with type 2 diabetes mellitus
    Gary T C Ko
    Department of Medicine and Therapeutics, Chinese University of Hong Kong, Shatin, Hong Kong SAR, China
    CMAJ 180:919-26. 2009
    ..Given the phenotypic heterogeneity of diabetes, therapy targeted at insulin status may maximize benefits and minimize harm...
  35. pmc Low LDL cholesterol, albuminuria, and statins for the risk of cancer in type 2 diabetes: the Hong Kong diabetes registry
    Xilin Yang
    Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Hong Kong SAR, China
    Diabetes Care 32:1826-32. 2009
    ..We explored the 1) interaction between low LDL cholesterol and albuminuria and 2) interaction between copresence of these two risk factors and statin use for cancer in type 2 diabetes...
  36. pmc Associations of hyperglycemia and insulin usage with the risk of cancer in type 2 diabetes: the Hong Kong diabetes registry
    Xilin Yang
    Department of Medicine and Therapeutics, The Chinese Universityof Hong Kong, Hong Kong, People s Republic of China
    Diabetes 59:1254-60. 2010
    ..CONCLUSIONS In Chinese patients with type 2 diabetes, hyperglycemia predicts cancer, whereas insulin usage was associated with a reduced cancer risk...
  37. doi request reprint Predicting values of lipids and white blood cell count for all-site cancer in type 2 diabetes
    Xilin Yang
    Department of Medicine and Therapeutics, The Chinese University of Hong Kong, The Prince of Wales Hospital, Shatin, Hong Kong SAR, China
    Endocr Relat Cancer 15:597-607. 2008
    ..The adjusted area under receiver operating characteristic curve was 0.712. In conclusion, BMI, lipids and WBC count have predicting values for cancer...
  38. doi request reprint Use of sulphonylurea and cancer in type 2 diabetes-The Hong Kong Diabetes Registry
    Xilin Yang
    Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Shatin, Hong Kong, China
    Diabetes Res Clin Pract 90:343-51. 2010
    ..Hyperglycaemia is a risk factor for cancer and some sulphonylureas have anti-oxidant properties. This study examined associations between use of sulphonylureas and cancer...
  39. doi request reprint Low triglyceride and nonuse of statins is associated with cancer in type 2 diabetes mellitus: the Hong Kong Diabetes Registry
    Xilin Yang
    Department of Medicine and Therapeutics, The Prince of Wales Hospital, Hong Kong, China
    Cancer 117:862-71. 2011
    ..In this analysis, the authors explored associations of cancer risk with high/low triglyceride in T2DM and possible modifying effects of statins on this risk association, if any...
  40. ncbi request reprint Risk factors in V-shaped risk associations with all-cause mortality in type 2 diabetes-The Hong Kong Diabetes Registry
    Wing Yee So
    Department of Medicine and Therapeutics, The Chinese University of Hong Kong, China
    Diabetes Metab Res Rev 24:238-46. 2008
    ..Body mass index (BMI) is associated with death in a V-shaped manner in general populations but it is unknown whether BMI or other risk factors also exhibit V-shaped relationships with death in type 2 diabetic patients...
  41. ncbi request reprint Associations between dietary habits and risk factors for cardiovascular diseases in a Hong Kong Chinese working population--the "Better Health for Better Hong Kong" (BHBHK) health promotion campaign
    Gary T C Ko
    Department of Medicine, Alice HML Nethersole Hospital, 11 Chuen On Road, Tai Po, NT, Hong Kong
    Asia Pac J Clin Nutr 16:757-65. 2007
    ..In conclusion, there were close associations between dietary habits and risk factors for cardiovascular diseases in Hong Kong. More effective community education about healthy lifestyle is required in Hong Kong...
  42. doi request reprint Metabolic syndrome by the new IDF criteria in Hong Kong Chinese adolescents and its prediction by using body mass index
    Alice P S Kong
    Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong SAR, China
    Acta Paediatr 97:1738-42. 2008
    ..We estimated the rate of MES by these new IDF criteria and investigated the use of body mass index (BMI) in predicting MES in Chinese adolescents...
  43. pmc Association between physical activity and cardiovascular risk in Chinese youth independent of age and pubertal stage
    Alice P S Kong
    Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong SAR, China
    BMC Public Health 10:303. 2010
    ..We examined the association of self-reported level of physical activity and cardiovascular risk in Hong Kong Chinese youth of school-age...
  44. pmc Low HDL cholesterol, metformin use, and cancer risk in type 2 diabetes: the Hong Kong Diabetes Registry
    Xilin Yang
    Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Hong Kong Special Administrative Region, China
    Diabetes Care 34:375-80. 2011
    ..Both metformin and apolipoprotein A1 activate the AMPK signaling pathway. We hypothesize that the anticancer effects of metformin may be particularly evident in type 2 diabetic patients with low HDL cholesterol...
  45. doi request reprint Serum concentrations of insulin-like growth factor-I, insulin-like growth factor binding protein-3 and cardiovascular risk factors in adolescents
    Alice P S Kong
    Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, NT, Hong Kong SAR, China
    Ann Clin Biochem 48:263-9. 2011
    ..We aimed to investigate the associations between serum concentrations of IGF-I and IGF binding protein-3 (IGFBP-3) and cardiovascular risk factors in adolescents...
  46. ncbi request reprint Association of testosterone, insulin-like growth factor-I, and C-reactive protein with metabolic syndrome in Chinese middle-aged men with a family history of type 2 diabetes
    Peter C Y Tong
    Department of Medicine and Therapeutics, School of Public Health, The Chinese University of Hong Kong, The Prince of Wales Hospital, Shatin, Hong Kong
    J Clin Endocrinol Metab 90:6418-23. 2005
    ..Age-related declines in testosterone and IGF-I are associated with deposition of visceral fat, a component of the metabolic syndrome (MES)...
  47. pmc Independent associations between low-density lipoprotein cholesterol and cancer among patients with type 2 diabetes mellitus
    Xilin Yang
    The Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Hong Kong, China
    CMAJ 179:427-37. 2008
    ..The risk association between low-density lipoprotein (LDL) cholesterol and cancer remains controversial and largely unexplored for people not receiving statin therapy...
  48. ncbi request reprint Stabilization and regression of albuminuria in Chinese patients with type 2 diabetes: a one-year randomized study of valsartan versus enalapril
    Gary T C Ko
    Department of Medicine, Alice Ho Miu Ling Nethersole Hospital, Hong Kong
    Adv Ther 22:155-62. 2005
    ..Fewer adverse events were reported with valsartan, but both drugs appear to be relatively safe...
  49. ncbi request reprint The renoprotective effects of structured care in a clinical trial setting in type 2 diabetic patients with nephropathy
    Wilson Y S Leung
    Department of Medicine and Therapeutics, The Chinese University of Hong Kong, The Prince of Wales Hospital, Shatin, N T, Hong Kong, SAR
    Nephrol Dial Transplant 19:2519-25. 2004
    ..In this subgroup analysis from the RENAAL Study, we hypothesized that the intensive care received by patients in a clinical trial setting also reduced the rate of decline in renal function through optimization of all risk factors...
  50. doi request reprint Risk associations of obesity with sugar-sweetened beverages and lifestyle factors in Chinese: the 'Better Health for Better Hong Kong' health promotion campaign
    G T Ko
    Department of Medicine and Therapeutic, Prince of Wales Hospital, The Chinese University of Hong Kong, Shatin, Hong Kong SAR, China
    Eur J Clin Nutr 64:1386-92. 2010
    ..Similar data are lacking in Chinese populations with rapid nutritional transition. We aimed to examine the association between SSB intake, lifestyle factors and obesity in Hong Kong Chinese...
  51. ncbi request reprint Association between tumour necrosis factor-alpha G-308A polymorphism and risk of nephropathy in obese Chinese type 2 diabetic patients
    Ying Wang
    Divison of Endocrinology, Department of Medicine and Therapeutics, Prince of Wales Hospital, The Chinese University of Hong Kong, Shatin, Hong Kong SAR
    Nephrol Dial Transplant 20:2733-8. 2005
    ..We hypothesized that this polymorphism might interact with obesity to affect development of diabetic nephropathy...
  52. doi request reprint Associations of sleep duration with obesity and serum lipid profile in children and adolescents
    Alice P Kong
    Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Hong Kong Special Administrative Region
    Sleep Med 12:659-65. 2011
    ..The association between sleep duration, obesity, and serum lipid profile in the youth population is under-explored...
  53. ncbi request reprint Waist circumference and BMI cut-off based on 10-year cardiovascular risk: evidence for "central pre-obesity"
    Gary T C Ko
    Department of Medicine, Alice Ho Miu Ling Nethersole Hospital, 11, Chuen On Road, Tai Po, Hong Kong, China
    Obesity (Silver Spring) 15:2832-9. 2007
    ....
  54. ncbi request reprint Prevalence of obesity, overweight and underweight in a Hong Kong community: the United Christian Nethersole Community Health Service (UCNCHS) primary health care program 1996-1997
    Gary T C Ko
    Department of Medicine, Alice Ho Miu Ling Nethersole Hospital, 11, Chuen On Road, Tai Po, Hong Kong, China
    Asia Pac J Clin Nutr 15:236-41. 2006
    ..5 kg/m2. In conclusion, a significant proportion of Hong Kong Chinese had a BMI > or = 25 kg/m2. Among Hong Kong Chinese aged < 30 years, the prevalence of underweight was also high...
  55. ncbi request reprint Rosiglitazone versus bedtime insulin in the treatment of patients with conventional oral antidiabetic drug failure: a 1-year randomized clinical trial
    Gary T C Ko
    Department of Medicine, AH Nethersole Hospital, Tai Po, Hong Kong, China
    Adv Ther 23:799-808. 2006
    ..Rosiglitazone was also associated with improved high-density lipoprotein cholesterol levels. The addition of rosiglitazone may offer a safe and effective alternative to bedtime insulin treatment...
  56. pmc Diabetes-related distress and physical and psychological health in chinese type 2 diabetic patients
    Rose Z W Ting
    Department of Medicine and Therapeutics, The Chinese University of Hong Kong, The Prince of Wales Hospital, Hong Kong S A R, China
    Diabetes Care 34:1094-6. 2011
    ..To validate a Chinese version of the Diabetes Distress Scale (CDDS)...
  57. ncbi request reprint A 10-week Tai-Chi program improved the blood pressure, lipid profile and SF-36 scores in Hong Kong Chinese women
    Gary T C Ko
    Department of Medicine, AH Nethersole Hospital, NT, Hong Kong
    Med Sci Monit 12:CR196-9. 2006
    ..Tai-Chi is a traditional Chinese aerobic exercise. We aimed to assess the short-term effects of Tai-Chi on the clinical parameters and health-related quality of life (QOL) in Hong Kong Chinese...
  58. ncbi request reprint Low levels of awareness of suboptimal health conditions in a high-risk working population: the "better health for better Hong Kong" health promotion campaign
    Gary T C Ko
    Department of Medicine, Alice HML Nethersole Hospital, 11 Chuen On Road, Tai Po, NT, Hong Kong
    Int J Behav Med 14:63-9. 2007
    ..Massive public education is an important and essential, although it may not be self-sufficient, factor to reduce the socioeconomic impacts of this epidemic...
  59. ncbi request reprint Oral alendronate increases bone mineral density in postmenopausal women with primary hyperparathyroidism
    C C Chow
    Department of Medicine and Therapeutics, The Prince of Wales Hospital, The Chinese University of Hong Kong, Shatin, Hong Kong
    J Clin Endocrinol Metab 88:581-7. 2003
    ..008 for trend). N-telopeptide/creatinine ratio did not change with placebo. Alendronate improves BMD and reduces bone turnover markers in postmenopausal women with PHP...
  60. ncbi request reprint Both obesity and lack of physical activity are associated with a less favorable health-related quality of life in Hong Kong Chinese
    Gary T C Ko
    Department of Medicine, Alice HML Nethersole Hospital, Tai Po, NT, Hong Kong
    Am J Health Promot 21:49-52. 2006
    ..To investigate the relationships among obesity, physical activity and quality of life (QOL) in Hong Kong Chinese adults...
  61. pmc Effects of age on plasma glucose levels in non-diabetic Hong Kong Chinese
    Gary T C Ko
    Department of Medicine, Alice Ho Miu Ling Nethersole Hospital, Tai Po, Hong Kong, China
    Croat Med J 47:709-13. 2006
    ..To analyze the relationship between age and plasma glucose levels in Hong Kong Chinese population...
  62. ncbi request reprint Effects of telephone-based peer support in patients with type 2 diabetes mellitus receiving integrated care: a randomized clinical trial
    Juliana C N Chan
    Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong2Hong Kong Institute of Diabetes and Obesity, The Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong3Asia Diabetes Foundatio
    JAMA Intern Med 174:972-81. 2014
    ..CONCLUSIONS AND RELEVANCE In patients with T2DM receiving integrated care, peer support did not improve cardiometabolic risks or psychological well-being. TRIAL REGISTRATION clinicaltrials.gov Identifier: NCT00950716. ..
  63. doi request reprint Pharmacogenetic analysis of lipid responses to rosuvastatin in Chinese patients
    Miao Hu
    Department of Medicine and Therapeutics, Prince of Wales Hospital, Shatin, Hong Kong SAR
    Pharmacogenet Genomics 20:634-7. 2010
    ..This study identified some genetic determinants of LDL-C response to rosuvastatin in Chinese patients, which need to be replicated in other populations...
  64. pmc The problem of obesity among adolescents in Hong Kong: a comparison using various diagnostic criteria
    Gary T C Ko
    The Hong Kong Institute of Diabetes and Obesity, Hong Kong SAR, China
    BMC Pediatr 8:10. 2008
    ..Obesity is now a global epidemic. In this study, we aimed to assess the rates of obesity using several major diagnostic criteria in Chinese school adolescents in Hong Kong...
  65. ncbi request reprint Progression to impaired glucose regulation, diabetes and metabolic syndrome in Chinese women with a past history of gestational diabetes
    Wing Hung Tam
    Department of Obstetrics and Gynaecology, The Chinese University of Hong Kong, Hong Kong SAR
    Diabetes Metab Res Rev 23:485-9. 2007
    ..To examine the risk of developing impaired glucose regulation (IGR), diabetes mellitus (DM) and metabolic syndrome (MetS) in Chinese women with history of gestational diabetes...
  66. ncbi request reprint Waist circumference gain compared with waist circumference as predictors of type 2 diabetes risk
    Grete Heinz
    Am J Clin Nutr 82:1134; author reply 1135. 2005
  67. ncbi request reprint Waist girth normalized to body build in obesity assessment
    Grete Heinz
    Asia Pac J Clin Nutr 14:60-8. 2005
    ..6/67.4). With %WD normalized for WRG, hence unaffected by intra-group or inter-group variations in the Chest Sum, %WD thresholds may better identify health risks linked to abdominal obesity than existing WG thresholds...
  68. ncbi request reprint No mutation in the KCNE3 potassium channel gene in Chinese thyrotoxic hypokalaemic periodic paralysis patients
    Nelson L S Tang
    Department of Chemical Pathology, Faculty of Medicine, The Chinese University of Hong Kong, Kong Kong
    Clin Endocrinol (Oxf) 61:109-12. 2004
    ..We studied 79 Chinese TPP patients by DNA sequencing of the entire coding sequence of KCNE3 to determine if this gene is the cause of TPP in Chinese patients...
  69. ncbi request reprint The alpha(1S) subunit of the L-type calcium channel is not a predisposition gene for thyrotoxic periodic paralysis
    Nelson L S Tang
    Department of Chemical Pathology, Faculty of Medicine, The Chinese Univerisity of Hong Kong SAR, China
    Clin Endocrinol (Oxf) 66:229-34. 2007
    ..In this study we have examined 48 genetic polymorphisms in the CACNA1S gene and genotyped a tagging set of representative polymorphisms to determine the role of this gene in TPP...
  70. ncbi request reprint Metabolic syndrome or "central obesity syndrome"?
    Gary T C Ko
    Diabetes Care 29:752. 2006