Verner Knott

Summary

Publications

  1. ncbi request reprint Baseline-dependent modulating effects of nicotine on voluntary and involuntary attention measured with brain event-related P3 potentials
    Verner Knott
    University of Ottawa Institute of Mental Health Research, Ottawa, Ontario, Canada Neuroscience Program, Department of Cellular and Molecular Medicine, University of Ottawa, Ottawa, Ontario, Canada School of Psychology, University of Ottawa, Ottawa, Ontario, Canada Electronic address
    Pharmacol Biochem Behav 122:107-17. 2014
  2. pmc Nicotine, Auditory Sensory Memory, and sustained Attention in a Human Ketamine Model of Schizophrenia: Moderating Influence of a Hallucinatory Trait
    Verner Knott
    Institute of Mental Health Research, University of Ottawa Ottawa, ON, Canada Neuroscience Program, Department of Cellular and Molecular Medicine, University of Ottawa Ottawa, ON, Canada School of Psychology, University of Ottawa Ottawa, ON, Canada Institute of Cognitive Science, Carleton University Ottawa, ON, Canada Royal Ottawa Mental Health Centre Ottawa, ON, Canada
    Front Pharmacol 3:172. 2012
  3. ncbi request reprint The moderating influence of nicotine and smoking on resting-state mood and EEG changes in remitted depressed patients during tryptophan depletion
    Verner Knott
    University of Ottawa Institute of Mental Health Research, Ottawa, ON, Canada Department of Psychology, University of Ottawa, Ottawa, ON, Canada Department of Psychology, Carleton University, Ottawa, ON, Canada Institute of Cognitive Science, Carleton University, Ottawa, ON, Canada Department of Psychiatry, University of Ottawa, Ottawa, ON, Canada Electronic address
    Biol Psychol 94:545-55. 2013
  4. ncbi request reprint Baseline dependency of nicotine's sensory gating actions: similarities and differences in low, medium and high P50 suppressors
    Verner Knott
    University of Ottawa Institute of Mental Health Research, Ottawa, Canada
    J Psychopharmacol 27:790-800. 2013
  5. doi request reprint Neural expression of nicotine's antidepressant properties during tryptophan depletion: an EEG study in healthy volunteers at risk for depression
    Verner Knott
    University of Ottawa Institute of Mental Health Research, Ottawa, ON, Canada
    Biol Psychol 91:190-200. 2012
  6. doi request reprint A pilot study of electrocortical activity in dysfunctional anger: decreased frontocortical activation, impaired attention control, and diminished behavioral inhibition
    Natalia Jaworska
    University of Ottawa Institute of Mental Health Research, Ottawa, Ontario, Canada
    Aggress Behav 38:469-80. 2012
  7. pmc Auditory P3 in antidepressant pharmacotherapy treatment responders, non-responders and controls
    Natalia Jaworska
    University of Ottawa, Institute of Mental Health Research, Ottawa, Ont, Canada Department of Psychology, University of Ottawa, Ottawa, Ont, Canada Department of Psychiatry, Hotchkiss Brain Institute HBI, Alberta Children s Hospital Research Institute ACRI, University of Calgary, Calgary, Alta, Canada Electronic address
    Eur Neuropsychopharmacol 23:1561-9. 2013
  8. ncbi request reprint Neural effects of nicotine during auditory selective attention in smokers: an event-related potential study
    Verner Knott
    University of Ottawa Institute of Mental Health Research, Ottawa, Canada
    Neuropsychobiology 53:115-26. 2006
  9. ncbi request reprint Event-related potentials in young and elderly adults during a visual spatial working memory task
    Verner Knott
    Department of Psychiatry, University of Ottawa, Canada
    Clin EEG Neurosci 35:185-92. 2004
  10. ncbi request reprint Electrocortical effects of acute tryptophan depletion on emotive facial processing in depression-prone individuals
    Natalia Jaworska
    University of Ottawa Institute of Mental Health Research, Ottawa, ON, Canada Department of Psychology, University of Ottawa, Ottawa, ON, Canada
    Eur Neuropsychopharmacol 20:473-86. 2010

Collaborators

Detail Information

Publications25

  1. ncbi request reprint Baseline-dependent modulating effects of nicotine on voluntary and involuntary attention measured with brain event-related P3 potentials
    Verner Knott
    University of Ottawa Institute of Mental Health Research, Ottawa, Ontario, Canada Neuroscience Program, Department of Cellular and Molecular Medicine, University of Ottawa, Ottawa, Ontario, Canada School of Psychology, University of Ottawa, Ottawa, Ontario, Canada Electronic address
    Pharmacol Biochem Behav 122:107-17. 2014
    ....
  2. pmc Nicotine, Auditory Sensory Memory, and sustained Attention in a Human Ketamine Model of Schizophrenia: Moderating Influence of a Hallucinatory Trait
    Verner Knott
    Institute of Mental Health Research, University of Ottawa Ottawa, ON, Canada Neuroscience Program, Department of Cellular and Molecular Medicine, University of Ottawa Ottawa, ON, Canada School of Psychology, University of Ottawa Ottawa, ON, Canada Institute of Cognitive Science, Carleton University Ottawa, ON, Canada Royal Ottawa Mental Health Centre Ottawa, ON, Canada
    Front Pharmacol 3:172. 2012
    ..Conclusions: Nicotine alleviated ketamine-induced sensory memory impairment and improved attention, particularly in individuals prone to HD...
  3. ncbi request reprint The moderating influence of nicotine and smoking on resting-state mood and EEG changes in remitted depressed patients during tryptophan depletion
    Verner Knott
    University of Ottawa Institute of Mental Health Research, Ottawa, ON, Canada Department of Psychology, University of Ottawa, Ottawa, ON, Canada Department of Psychology, Carleton University, Ottawa, ON, Canada Institute of Cognitive Science, Carleton University, Ottawa, ON, Canada Department of Psychiatry, University of Ottawa, Ottawa, ON, Canada Electronic address
    Biol Psychol 94:545-55. 2013
    ..These findings indicate a role for nicotinic receptors in disordered mood. ..
  4. ncbi request reprint Baseline dependency of nicotine's sensory gating actions: similarities and differences in low, medium and high P50 suppressors
    Verner Knott
    University of Ottawa Institute of Mental Health Research, Ottawa, Canada
    J Psychopharmacol 27:790-800. 2013
    ....
  5. doi request reprint Neural expression of nicotine's antidepressant properties during tryptophan depletion: an EEG study in healthy volunteers at risk for depression
    Verner Knott
    University of Ottawa Institute of Mental Health Research, Ottawa, ON, Canada
    Biol Psychol 91:190-200. 2012
    ..These findings indicate that in depression prone individuals, nicotine acts to stabilize the mood lowering and associated frontal functional asymmetry elicited by an acute decrease in brain serotonin...
  6. doi request reprint A pilot study of electrocortical activity in dysfunctional anger: decreased frontocortical activation, impaired attention control, and diminished behavioral inhibition
    Natalia Jaworska
    University of Ottawa Institute of Mental Health Research, Ottawa, Ontario, Canada
    Aggress Behav 38:469-80. 2012
    ..Such impairments likely extend beyond the laboratory setting, and may associate with aggressive acts in real life...
  7. pmc Auditory P3 in antidepressant pharmacotherapy treatment responders, non-responders and controls
    Natalia Jaworska
    University of Ottawa, Institute of Mental Health Research, Ottawa, Ont, Canada Department of Psychology, University of Ottawa, Ottawa, Ont, Canada Department of Psychiatry, Hotchkiss Brain Institute HBI, Alberta Children s Hospital Research Institute ACRI, University of Calgary, Calgary, Alta, Canada Electronic address
    Eur Neuropsychopharmacol 23:1561-9. 2013
    ..These results suggest that greater (or control-like) baseline P3a/b amplitudes are associated with a positive antidepressant response, and that gender differences characterize the P3 and, by extension, basic attentive processes. ..
  8. ncbi request reprint Neural effects of nicotine during auditory selective attention in smokers: an event-related potential study
    Verner Knott
    University of Ottawa Institute of Mental Health Research, Ottawa, Canada
    Neuropsychobiology 53:115-26. 2006
    ..The findings are discussed in relation to the stimulus filter theory of smoking, and with respect to nicotine's actions on involuntary and controlled aspects of selective attention processes...
  9. ncbi request reprint Event-related potentials in young and elderly adults during a visual spatial working memory task
    Verner Knott
    Department of Psychiatry, University of Ottawa, Canada
    Clin EEG Neurosci 35:185-92. 2004
    ....
  10. ncbi request reprint Electrocortical effects of acute tryptophan depletion on emotive facial processing in depression-prone individuals
    Natalia Jaworska
    University of Ottawa Institute of Mental Health Research, Ottawa, ON, Canada Department of Psychology, University of Ottawa, Ottawa, ON, Canada
    Eur Neuropsychopharmacol 20:473-86. 2010
    ..The N170 was not modulated by treatment, but was affected by emotive valence. Therefore, ATD enhanced ERP-indexed early processing of sad facial expressions, and altered the processing of positive ones, in FH+ individuals...
  11. doi request reprint Acute tryptophan depletion effects on the vertex and late positive potentials to emotional faces in individuals with a family history of depression
    Natalia Jaworska
    Institute of Mental Health Research, School of Psychology, University of Ottawa, Ont, Canada
    Neuropsychobiology 65:28-40. 2012
    ..The VPP and LPP are thought to index the early and later stages of motivated attentional processing, respectively...
  12. doi request reprint Scalp- and sLORETA-derived loudness dependence of auditory evoked potentials (LDAEPs) in unmedicated depressed males and females and healthy controls
    Natalia Jaworska
    University of Ottawa Institute of Mental Health Research, Ottawa, ON, Canada
    Clin Neurophysiol 123:1769-78. 2012
    ....
  13. ncbi request reprint Nicotine and attention: event-related potential investigations in nonsmokers
    Verner Knott
    Clinical Neuroelectrophysiology and Cognitive Research Laboratory, University of Ottawa Institute of Mental Health Research at Royal Ottawa Mental Health Centre, 1145 Carling Avenue, Ottawa, ON, Canada K1Z 7K4
    Clin EEG Neurosci 40:11-20. 2009
    ....
  14. pmc Response prediction to antidepressants using scalp and source-localized loudness dependence of auditory evoked potential (LDAEP) slopes
    Natalia Jaworska
    University of Ottawa Institute of Mental Health Research, Ottawa, ON, Canada
    Prog Neuropsychopharmacol Biol Psychiatry 44:100-7. 2013
    ..This work confirms that certain LDAEP measures are associated with treatment outcome and appear to be differentially modulated with varying antidepressant drug regimens, though this should be confirmed using larger samples...
  15. doi request reprint Effects of nicotine on electroencephalography and affect in adolescent females with major depressive disorder: a pilot study
    Natalia Jaworska
    University of Ottawa Institute of Mental Health Research, Ottawa, ON, Canada
    J Addict Med 5:123-33. 2011
    ....
  16. doi request reprint Electrophysiological evidence of nicotine's distracter-filtering properties in non-smokers
    Verner Knott
    Clinical Neuroelectrophysiological and Cognitive Research Laboratory, University of Ottawa Institute of Mental Health Research, Royal Ottawa Mental Health Centre, Ottawa, ON, Canada
    J Psychopharmacol 25:239-48. 2011
    ..These findings and the behavioral-electrophysiological dissociation seen with nicotine are discussed in relation to theories of attention and smoking motivation...
  17. doi request reprint Neural effects of acute nicotinic treatment on visual spatial attention in non-smokers
    Dhrasti Shah
    University of Ottawa Institute of Mental Health Research, Canada
    Pharmacol Biochem Behav 100:228-36. 2011
    ....
  18. pmc α Power, α asymmetry and anterior cingulate cortex activity in depressed males and females
    Natalia Jaworska
    University of Ottawa Institute of Mental Health Research, Ottawa, ON, Canada
    J Psychiatr Res 46:1483-91. 2012
    ..Altered theta in the sgACC may reflect emotion regulation abnormalities in MDD...
  19. doi request reprint Resting electrocortical activity in adults with dysfunctional anger: a pilot study
    Natalia Jaworska
    University of Ottawa Institute of Mental Health Research, Ottawa, ON, Canada
    Psychiatry Res 203:229-36. 2012
    ..Enhanced beta(1) activity may index greater tonic cortical arousal or a chronic hypervigilant state, which may predispose individuals with dysfunctional anger to over-react to relatively innocuous stimuli...
  20. doi request reprint Sensory gating and source analysis of the auditory P50 in low and high suppressors
    Verner Knott
    University of Ottawa Institute of Mental Health Research, Ottawa, ON, Canada
    Neuroimage 44:992-1000. 2009
    ..These findings suggest that impaired gating of the kind evident in schizophrenia may involve the deficient functioning of multiple interconnected and temporally overlapping activated brain regions...
  21. ncbi request reprint EEG correlates of imagery-induced cigarette craving in male and female smokers
    Verner Knott
    Royal Ottawa Mental Health Centre, Ottawa, Ontario, Canada
    Addict Behav 33:616-21. 2008
    ..This imagery-elicited neuroelectric profile, appearing to reflect opposing actions of reward and withdrawal, suggests that EEG may be a sensitive tool for probing the multidimensional nature of craving...
  22. ncbi request reprint Effects of tryptophan depletion on acute smoking abstinence symptoms and the acute smoking response
    Mary Perugini
    Department of Psychology, Rehabilitation Centre, Ottawa Hospital, Ottawa, ON, Canada
    Pharmacol Biochem Behav 74:513-22. 2003
    ..These results, although not supporting a role for the serotonergic system in acute smoking and early smoking abstinence symptoms, are discussed in relation to the neuropharmacology of smoking behavior and suggestions for future work...
  23. pmc The temporal electrocortical profile of emotive facial processing in depressed males and females and healthy controls
    Natalia Jaworska
    University of Ottawa Institute of Mental Health Research, Department of Psychology, University of Ottawa, Ottawa, ON, Canada
    J Affect Disord 136:1072-81. 2012
    ....
  24. ncbi request reprint Effects of acute cholecystokinin infusion on hemispheric EEG asymmetry and coherence in healthy volunteers
    Verner Knott
    Department of Psychiatry, University of Ottawa, Ottawa, Ontario, Canada
    Prog Neuropsychopharmacol Biol Psychiatry 27:179-84. 2003
    ..These findings support the contention that functional imbalance of the temporal cortex, perhaps mediated by CCK-4, is involved in panic disorder (PD)...
  25. ncbi request reprint Effects of stimulus modality and response mode on the P300 event-related potential differentiation of young and elderly adults
    Verner Knott
    Department of Psychiatry, University of Ottawa, Institute of Mental Health Research Royal Ottawa Hospital, Ottawa, Canada
    Clin Electroencephalogr 34:182-90. 2003
    ..Implications of the findings are discussed in relation to P300 applications in the clinical assessment of dementia and aging-associated cognitive alterations...