Matty Knight

Summary

Publications

  1. pmc Reversing the resistance phenotype of the Biomphalaria glabrata snail host Schistosoma mansoni infection by temperature modulation
    Wannaporn Ittiprasert
    Biomedical Research Institute, Rockville, Maryland, United States of America
    PLoS Pathog 8:e1002677. 2012
  2. pmc Biomphalaria glabrata peroxiredoxin: effect of schistosoma mansoni infection on differential gene regulation
    Matty Knight
    Biomedical Research Institute, 12111 Parklawn Drive, Rockville, MD 20852, USA
    Mol Biochem Parasitol 167:20-31. 2009
  3. pmc Polyethyleneimine (PEI) mediated siRNA gene silencing in the Schistosoma mansoni snail host, Biomphalaria glabrata
    Matty Knight
    Biomedical Research Institute, Rockville, Maryland, USA
    PLoS Negl Trop Dis 5:e1212. 2011
  4. pmc Non-random organization of the Biomphalaria glabrata genome in interphase Bge cells and the spatial repositioning of activated genes in cells co-cultured with Schistosoma mansoni
    Matty Knight
    Biomedical Research Institute, 12111 Parklawn Dr Rockville, MD 20852, USA
    Int J Parasitol 41:61-70. 2011
  5. pmc Nimbus (BgI): an active non-LTR retrotransposon of the Schistosoma mansoni snail host Biomphalaria glabrata
    Nithya Raghavan
    Biomedical Research Institute BRI, 12111 Parklawn Drive, Rockville, MD 20852, USA
    Int J Parasitol 37:1307-18. 2007
  6. pmc Schistosoma mansoni infection of juvenile Biomphalaria glabrata induces a differential stress response between resistant and susceptible snails
    Wannaporn Ittiprasert
    Biomedical Research Institute, Rockville, MD 20852, USA
    Exp Parasitol 123:203-11. 2009
  7. pmc Identification and characterisation of functional expressed sequence tags-derived simple sequence repeat (eSSR) markers for genetic linkage mapping of Schistosoma mansoni juvenile resistance and susceptibility loci in Biomphalaria glabrata
    Wannaporn Ittiprasert
    Biomedical Research Institute, Rockville, MD 20852, USA
    Int J Parasitol 43:669-77. 2013
  8. pmc Identification of immediate response genes dominantly expressed in juvenile resistant and susceptible Biomphalaria glabrata snails upon exposure to Schistosoma mansoni
    Wannaporn Ittiprasert
    Biomedical Research Institute, Rockville, MD 20852, USA
    Mol Biochem Parasitol 169:27-39. 2010
  9. ncbi Comparative gene analysis of Biomphalaria glabrata hemocytes pre- and post-exposure to miracidia of Schistosoma mansoni
    Nithya Raghavan
    Biomedical Research Institute, Rockville, MD 20852, USA
    Mol Biochem Parasitol 126:181-91. 2003
  10. pmc The NIH-NIAID schistosomiasis resource center
    Fred A Lewis
    Biomedical Research Institute, Rockville, Maryland, United States of America
    PLoS Negl Trop Dis 2:e267. 2008

Collaborators

Detail Information

Publications12

  1. pmc Reversing the resistance phenotype of the Biomphalaria glabrata snail host Schistosoma mansoni infection by temperature modulation
    Wannaporn Ittiprasert
    Biomedical Research Institute, Rockville, Maryland, United States of America
    PLoS Pathog 8:e1002677. 2012
    ..This study of reversing snail susceptibility phenotypes to S. mansoni provides an opportunity to directly track molecular pathway(s) that underlie the B. glabrata snail's ability to either sustain or destroy the S. mansoni parasite...
  2. pmc Biomphalaria glabrata peroxiredoxin: effect of schistosoma mansoni infection on differential gene regulation
    Matty Knight
    Biomedical Research Institute, 12111 Parklawn Drive, Rockville, MD 20852, USA
    Mol Biochem Parasitol 167:20-31. 2009
    ..Enzymatic analysis of the purified, recombinant BgPrx4 revealed the snail sequence to function as Prx but with an unusual ability to use both thioredoxin and glutathione as substrates...
  3. pmc Polyethyleneimine (PEI) mediated siRNA gene silencing in the Schistosoma mansoni snail host, Biomphalaria glabrata
    Matty Knight
    Biomedical Research Institute, Rockville, Maryland, USA
    PLoS Negl Trop Dis 5:e1212. 2011
    ....
  4. pmc Non-random organization of the Biomphalaria glabrata genome in interphase Bge cells and the spatial repositioning of activated genes in cells co-cultured with Schistosoma mansoni
    Matty Knight
    Biomedical Research Institute, 12111 Parklawn Dr Rockville, MD 20852, USA
    Int J Parasitol 41:61-70. 2011
    ..We believe that this is not only the first time that gene-repositioning studies have been attempted in a mollusc but also demonstrates a parasite influencing the interphase genome organization of its host...
  5. pmc Nimbus (BgI): an active non-LTR retrotransposon of the Schistosoma mansoni snail host Biomphalaria glabrata
    Nithya Raghavan
    Biomedical Research Institute BRI, 12111 Parklawn Drive, Rockville, MD 20852, USA
    Int J Parasitol 37:1307-18. 2007
    ..Nimbus (BgI) represents the first complete mobile element characterised from a mollusk that appears to be transcriptionally active and is widely distributed in snails of the neotropics and the Old World...
  6. pmc Schistosoma mansoni infection of juvenile Biomphalaria glabrata induces a differential stress response between resistant and susceptible snails
    Wannaporn Ittiprasert
    Biomedical Research Institute, Rockville, MD 20852, USA
    Exp Parasitol 123:203-11. 2009
    ..Understanding molecular events involved in stress response transcriptional regulation of Hsp 70 in juvenile snails could pave a way towards the identification of genes involved in schistosome/snail interactions...
  7. pmc Identification and characterisation of functional expressed sequence tags-derived simple sequence repeat (eSSR) markers for genetic linkage mapping of Schistosoma mansoni juvenile resistance and susceptibility loci in Biomphalaria glabrata
    Wannaporn Ittiprasert
    Biomedical Research Institute, Rockville, MD 20852, USA
    Int J Parasitol 43:669-77. 2013
    ..mansoni infection in B. glabrata are not only on the same linkage group but lie within a short distance (42cM) of each other...
  8. pmc Identification of immediate response genes dominantly expressed in juvenile resistant and susceptible Biomphalaria glabrata snails upon exposure to Schistosoma mansoni
    Wannaporn Ittiprasert
    Biomedical Research Institute, Rockville, MD 20852, USA
    Mol Biochem Parasitol 169:27-39. 2010
    ..glabrata in relation to S. mansoni exposure...
  9. ncbi Comparative gene analysis of Biomphalaria glabrata hemocytes pre- and post-exposure to miracidia of Schistosoma mansoni
    Nithya Raghavan
    Biomedical Research Institute, Rockville, MD 20852, USA
    Mol Biochem Parasitol 126:181-91. 2003
    ..However, identification of this and other transcripts from these cells by the EST approach provides a useful resource towards elucidating the molecular basis of resistance/susceptibility in this snail-host parasite relationship...
  10. pmc The NIH-NIAID schistosomiasis resource center
    Fred A Lewis
    Biomedical Research Institute, Rockville, Maryland, United States of America
    PLoS Negl Trop Dis 2:e267. 2008
    ....
  11. ncbi The snail (Biomphalaria glabrata) genome project
    Nithya Raghavan
    Biomedical Research Institute, 12111 Parklawn Drive, Rockville, MD 20852, USA
    Trends Parasitol 22:148-51. 2006
    ..The sequencing of the genome of this medically important snail is now underway...

Research Grants7

  1. A gene map for Biomphalaria glabrata, a S. mansoni host
    Matty Knight; Fiscal Year: 2005
    ..glabrata genome. ..
  2. A gene map for Biomphalaria glabrata, a S. mansoni host
    Matty Knight; Fiscal Year: 2006
    ..glabrata genome. ..
  3. A gene map for Biomphalaria glabrata, a S. mansoni host
    Matty Knight; Fiscal Year: 2007
    ..glabrata genome. ..
  4. A gene map for Biomphalaria glabrata, a S. mansoni host
    Matty Knight; Fiscal Year: 2007
    ..glabrata genome. ..
  5. A gene map for Biomphalaria glabrata, a S. mansoni host
    Matty Knight; Fiscal Year: 2009
    ..glabrata genome. ..
  6. A gene map for Biomphalaria glabrata, a S. mansoni host
    Matty Knight; Fiscal Year: 2009
    ..glabrata genome. ..