Julia A Knight

Summary

Publications

  1. pmc Accuracy of Self-Reported Breast Cancer Information among Women from the Ontario Site of the Breast Cancer Family Registry
    Andriana Barisic
    Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, ON, Canada M5G 1X5 Dalla Lana School of Public Health, University of Toronto, Toronto, ON, Canada M5T 3M7
    J Cancer Epidemiol 2012:310804. 2012
  2. pmc Assessing interactions between the associations of common genetic susceptibility variants, reproductive history and body mass index with breast cancer risk in the breast cancer association consortium: a combined case-control study
    Roger L Milne
    Genetic and Molecular Epidemiology Group, Human Cancer Genetics Programme, Spanish National Cancer Research Centre CNIO, Madrid, 28029, Spain
    Breast Cancer Res 12:R110. 2010
  3. doi request reprint Vitamin D association with estradiol and progesterone in young women
    Julia A Knight
    Prosserman Centre for Health Research, Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, ON, Canada
    Cancer Causes Control 21:479-83. 2010
  4. ncbi request reprint Optical spectroscopy of the breast in premenopausal women reveals tissue variation with changes in age and parity
    Julia A Knight
    Prosserman Centre for Health Research, Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, Ontario M5T 3L9, Canada
    Med Phys 37:419-26. 2010
  5. pmc Alcohol intake and cigarette smoking and risk of a contralateral breast cancer: The Women's Environmental Cancer and Radiation Epidemiology Study
    Julia A Knight
    Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, Canada
    Am J Epidemiol 169:962-8. 2009
  6. doi request reprint Family-based association study of IGF1 microsatellites and height, weight, and body mass index
    Gordon Fehringer
    Dalla Lana School of Public Health, University of Toronto, Toronto, Ontario, Canada
    J Hum Genet 55:255-8. 2010
  7. doi request reprint Vitamin D intake is negatively associated with promoter methylation of the Wnt antagonist gene DKK1 in a large group of colorectal cancer patients
    James B Rawson
    Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Canada
    Nutr Cancer 64:919-28. 2012
  8. ncbi request reprint Family-based genetic association study of insulin-like growth factor I microsatellite markers and premenopausal breast cancer risk
    Gordon Fehringer
    Dalla Lana School of Public Health, University of Toronto, Toronto, ON, Canada
    Breast Cancer Res Treat 118:415-24. 2009
  9. ncbi request reprint MSH2 118T>C and MSH6 159C>T promoter polymorphisms and the risk of colorectal cancer
    Miralem Mrkonjic
    Department of Pathology and Laboratory Medicine, Mount Sinai Hospital, Toronto, Ontario M5T 3L9, Canada
    Carcinogenesis 28:2575-80. 2007
  10. pmc Prospective associations of vitamin D with β-cell function and glycemia: the PROspective Metabolism and ISlet cell Evaluation (PROMISE) cohort study
    Sheena Kayaniyil
    Department of Nutritional Sciences, University of Toronto, Toronto, Ontario, Canada
    Diabetes 60:2947-53. 2011

Detail Information

Publications52

  1. pmc Accuracy of Self-Reported Breast Cancer Information among Women from the Ontario Site of the Breast Cancer Family Registry
    Andriana Barisic
    Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, ON, Canada M5G 1X5 Dalla Lana School of Public Health, University of Toronto, Toronto, ON, Canada M5T 3M7
    J Cancer Epidemiol 2012:310804. 2012
    ..The finding of this study can aid researchers in the use and design of self-administered treatment questionnaires...
  2. pmc Assessing interactions between the associations of common genetic susceptibility variants, reproductive history and body mass index with breast cancer risk in the breast cancer association consortium: a combined case-control study
    Roger L Milne
    Genetic and Molecular Epidemiology Group, Human Cancer Genetics Programme, Spanish National Cancer Research Centre CNIO, Madrid, 28029, Spain
    Breast Cancer Res 12:R110. 2010
    ....
  3. doi request reprint Vitamin D association with estradiol and progesterone in young women
    Julia A Knight
    Prosserman Centre for Health Research, Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, ON, Canada
    Cancer Causes Control 21:479-83. 2010
    ..We conducted a study to determine whether there is an association between circulating 25-hydroxyvitamin D (25(OH)D) and estradiol and progesterone in young women...
  4. ncbi request reprint Optical spectroscopy of the breast in premenopausal women reveals tissue variation with changes in age and parity
    Julia A Knight
    Prosserman Centre for Health Research, Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, Ontario M5T 3L9, Canada
    Med Phys 37:419-26. 2010
    ..IGF-1 has been linked in particular to premenopausal breast cancer...
  5. pmc Alcohol intake and cigarette smoking and risk of a contralateral breast cancer: The Women's Environmental Cancer and Radiation Epidemiology Study
    Julia A Knight
    Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, Canada
    Am J Epidemiol 169:962-8. 2009
    ..Smoking was not related to asynchronous contralateral breast cancer. In this, the largest study of asynchronous contralateral breast cancer to date, alcohol is a risk factor for the disease, as it is for a first primary breast cancer...
  6. doi request reprint Family-based association study of IGF1 microsatellites and height, weight, and body mass index
    Gordon Fehringer
    Dalla Lana School of Public Health, University of Toronto, Toronto, Ontario, Canada
    J Hum Genet 55:255-8. 2010
    ..This study does not support an association between IGF1 and these anthropometric measures. Study limitations, including sample size and capturing genetic variation at IGF1 with these markers, could mean associations were missed...
  7. doi request reprint Vitamin D intake is negatively associated with promoter methylation of the Wnt antagonist gene DKK1 in a large group of colorectal cancer patients
    James B Rawson
    Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Canada
    Nutr Cancer 64:919-28. 2012
    ..001) and a similar trend was observed in Ontario. These results suggest that vitamin D and other dietary/lifestyle factors may alter CRC risk by mediating extracellular Wnt inhibition...
  8. ncbi request reprint Family-based genetic association study of insulin-like growth factor I microsatellite markers and premenopausal breast cancer risk
    Gordon Fehringer
    Dalla Lana School of Public Health, University of Toronto, Toronto, ON, Canada
    Breast Cancer Res Treat 118:415-24. 2009
    ..14; 5'CA 18-20, P = 0.25; 5'CA >20, P = 0.20). The associations we found could be due to chance as many comparisons were made. Our results do not strongly support an association between these IGF1 variants and breast cancer risk...
  9. ncbi request reprint MSH2 118T>C and MSH6 159C>T promoter polymorphisms and the risk of colorectal cancer
    Miralem Mrkonjic
    Department of Pathology and Laboratory Medicine, Mount Sinai Hospital, Toronto, Ontario M5T 3L9, Canada
    Carcinogenesis 28:2575-80. 2007
    ..003 and P = 0.0001, respectively). The MSH2 -118T>C polymorphism was associated with strong family history of CRC in Ontario patients...
  10. pmc Prospective associations of vitamin D with β-cell function and glycemia: the PROspective Metabolism and ISlet cell Evaluation (PROMISE) cohort study
    Sheena Kayaniyil
    Department of Nutritional Sciences, University of Toronto, Toronto, Ontario, Canada
    Diabetes 60:2947-53. 2011
    ..To examine the prospective associations of baseline vitamin D [25-hydroxyvitamin D; 25(OH)D] with insulin resistance (IR), β-cell function, and glucose homeostasis in subjects at risk for type 2 diabetes...
  11. doi request reprint Association of 25(OH)D and PTH with metabolic syndrome and its traditional and nontraditional components
    Sheena Kayaniyil
    Department of Nutritional Sciences, University of Toronto, Toronto, Ontario, Canada
    J Clin Endocrinol Metab 96:168-75. 2011
    ..However, evidence to date is limited and inconsistent, and few studies have examined associations with nontraditional MetS components...
  12. doi request reprint Association of vitamin D related information from a telephone interview with 25-hydroxyvitamin D
    Harleen Sahota
    Prosserman Centre for Health Research, Samuel Lunenfeld Research Institute, Mount Sinai Hospital, 60 Murray Street, Toronto, Ontario, Canada
    Cancer Epidemiol Biomarkers Prev 17:232-8. 2008
    ..82 versus "none"; P = 0.0006). The R(2) was 0.29 for the summer model and was 0.21 for the winter model. Overall, there was evidence to suggest that questions designed to assess vitamin D exposure were in fact related to serum 25(OH)D...
  13. pmc Polymorphisms cMyc-N11S and p27-V109G and breast cancer risk and prognosis
    Jane C Figueiredo
    Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, Ontario, Canada
    BMC Cancer 7:99. 2007
    ..In this study, we focus on a rare non-synonymous polymorphism in cMyc (N11S) and a common polymorphism in p27 (V109G) and determine their role in risk and prognosis using data collected from the Ontario Breast Cancer Family Registry...
  14. doi request reprint Association between IGF1 CA microsatellites and mammographic density, anthropometric measures, and circulating IGF-I levels in premenopausal Caucasian women
    Gordon Fehringer
    Dalla Lana School of Public Health, University of Toronto, Toronto, ON, Canada
    Breast Cancer Res Treat 116:413-23. 2009
    ..Therefore, we examined the association of IGF1 polymorphisms with circulating IGF-I levels and mammographic density...
  15. pmc Beliefs about optimal age and screening frequency predict breast screening adherence in a prospective study of female relatives from the Ontario site of the Breast Cancer Family Registry
    Paul Ritvo
    Research, Prevention and Cancer Control, Cancer Care Ontario, 620 University Ave, Toronto, ON M5G 2L7, Canada
    BMC Public Health 12:518. 2012
    ..Although few studies have linked cognitive variables with adherence to mammography screening in women with family histories of breast and/or ovarian cancer, research studies suggest cognitive phenomena can be powerful adherence predictors...
  16. pmc Adherence to breast and ovarian cancer screening recommendations for female relatives from the Ontario site of the Breast Cancer Family Registry
    Michael A Campitelli
    Prevention and Cancer Control, Cancer Care Ontario, Toronto, Canada
    Eur J Cancer Prev 20:492-500. 2011
    ..76-4.05). Although the overall level of adherence among high-risk women is suboptimal in the community, women at a higher familial risk are adhering more often to cancer screening recommendations than women at a lower familial risk...
  17. doi request reprint Vitamin D from dietary intake and sunlight exposure and the risk of hormone-receptor-defined breast cancer
    Kristina M Blackmore
    Samuel Lunenfeld Research Institute, Mount Sinai Hospital, 60 Murray Street, Box 18, Toronto, Ontario, Canada M5T3L9
    Am J Epidemiol 168:915-24. 2008
    ..51, 1.22) tumors. This study suggests that vitamin D is associated with a reduced risk of breast cancer regardless of ER/PR status of the tumor. Future studies with a larger number of receptor-negative and mixed tumors are required...
  18. doi request reprint Ultraviolet sunlight exposure during adolescence and adulthood and breast cancer risk: a population-based case-control study among Ontario women
    Laura N Anderson
    Prevention and Cancer Control, Cancer Care Ontario, Toronto, Canada
    Am J Epidemiol 174:293-304. 2011
    ..This study suggests that factors suggestive of increased cutaneous production of vitamin D are associated with reduced breast cancer risk...
  19. ncbi request reprint Vitamin D and reduced risk of breast cancer: a population-based case-control study
    Julia A Knight
    Samuel Lunenfeld Research Institute, Mount Sinai Hospital, 60 Murray Street, Box 18, Toronto, Ontario, Canada M5T 3L9
    Cancer Epidemiol Biomarkers Prev 16:422-9. 2007
    ..We conducted a population-based case-control study to assess the evidence for a relationship between sources of vitamin D and breast cancer risk...
  20. pmc Combined effect of CCND1 and COMT polymorphisms and increased breast cancer risk
    Ummiye V Onay
    Fred A, Litwin Centre for Cancer Genetics, Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, Ontario, Canada
    BMC Cancer 8:6. 2008
    ..Several studies have also shown the relationship between estrogen and cell cycle progression through activation of CCND1 transcription...
  21. ncbi request reprint Ovarian cysts and breast cancer: results from the Women's Contraceptive and Reproductive Experiences Study
    Julia A Knight
    Prosserman Centre for Health Research, Samuel Lunenfeld Research Institute, Mount Sinai Hospital, 60 Murray Street, Box 18, Toronto, ON, Canada, M5T 3L9
    Breast Cancer Res Treat 109:157-64. 2008
    ..Additional studies are required to determine the specific cyst type(s) responsible for the observed relationship...
  22. ncbi request reprint No association between 25-hydroxyvitamin D and mammographic density
    Julia A Knight
    Samuel Lunenfeld Research Institute, Mount Sinai Hospital, 5th Floor, 60 Murray Street, Toronto, Ontario, Canada M5G 1X5
    Cancer Epidemiol Biomarkers Prev 15:1988-92. 2006
    ..Unlike some previous reports, vitamin D does not seem to be related to mammographic density in this cohort...
  23. pmc SNP-SNP interactions in breast cancer susceptibility
    Venüs Ummiye Onay
    Fred A Litwin Centre for Cancer Genetics, Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, Ontario, Canada
    BMC Cancer 6:114. 2006
    ..However, polygenic models suggest that multiple commonly occurring low to modestly penetrant SNPs of cancer related genes might have a greater effect on a disease when considered in combination...
  24. doi request reprint Vitamin D and calcium intakes and breast cancer risk in pre- and postmenopausal women
    Laura N Anderson
    Cancer Care Ontario, Toronto, Canada
    Am J Clin Nutr 91:1699-707. 2010
    ..Some evidence suggests that vitamin D may reduce breast cancer risk. Despite the biological interaction between vitamin D and calcium, few studies have evaluated their joint effects on breast cancer risk...
  25. pmc Missense polymorphisms in the adenomatous polyposis coli gene and colorectal cancer risk
    Sean P Cleary
    Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, Ontario, Canada
    Dis Colon Rectum 51:1467-73; discussion 1473-4. 2008
    ..Whereas truncating germline mutations of the adenomatous polyposis coli (APC) gene give rise to familial adenomatous polyposis, missense polymorphisms of APC may confer a weaker risk for colorectal cancer...
  26. pmc Family history of hormonal cancers and colorectal cancer risk: a case-control study conducted in Ontario
    Ji Hyun Jang
    Dalla Lana School of Public Health, University of Toronto, Toronto, Ontario, Canada
    Int J Cancer 125:918-25. 2009
    ..In conclusion, individuals with a first-degree kin with breast cancer may have a modest increased risk for CRC compared to individuals without...
  27. doi request reprint Prospective association of 25(OH)D with metabolic syndrome
    Sheena Kayaniyil
    Department of Nutritional Sciences, University of Toronto, Toronto, ON, Canada
    Clin Endocrinol (Oxf) 80:502-7. 2014
    ..Vitamin D may play a role in the aetiology of the metabolic syndrome (MetS), yet the majority of previous studies have been cross-sectional, and the limited number of prospective studies has yielded inconsistent results...
  28. pmc Influence of perceived breast cancer risk on screening behaviors of female relatives from the Ontario site of the Breast Cancer Family Registry
    Li Rita Zhang
    Prevention and Cancer Control, Cancer Care Ontario, 620 University Avenue, Toronto, Ontario M5G 2L7, Canada
    Eur J Cancer Prev 20:255-62. 2011
    ..These findings may inform educational messages for improving risk communication of women at elevated familial breast cancer risk...
  29. doi request reprint Perceived risk and adherence to breast cancer screening guidelines among women with a familial history of breast cancer: a review of the literature
    Meghan J Walker
    Prevention and Cancer Control, Cancer Care Ontario, Toronto, Ontario, Canada
    Breast 22:395-404. 2013
    ..A small positive association has been consistently demonstrated between perceived breast cancer risk and mammography use. Evidence specific to women with familial breast cancer risk has not been previously reviewed...
  30. ncbi request reprint MLH1 -93G>A promoter polymorphism and the risk of microsatellite-unstable colorectal cancer
    Stavroula Raptis
    Department of Pathology, Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, ON, Canada M5T 3L9
    J Natl Cancer Inst 99:463-74. 2007
    ..We investigated whether polymorphisms in DNA mismatch repair genes are associated with the risk of colorectal cancer...
  31. ncbi request reprint An inverse association between ovarian cysts and breast cancer in the breast cancer family registry
    Julia A Knight
    Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, Canada
    Int J Cancer 118:197-202. 2006
    ..Further study of ovarian cysts may increase our understanding of hormonal and other mechanisms of breast cancer etiology...
  32. ncbi request reprint Influence of young age at diagnosis and family history of breast or ovarian cancer on breast cancer outcomes in a population-based cohort study
    Jane C Figueiredo
    Samuel Lunenfeld Research Institute, Mount Sinai Hospital, 60 Murray Street, Box 18, Toronto, Ontario, Canada, M5T 3L9
    Breast Cancer Res Treat 105:69-80. 2007
    ....
  33. ncbi request reprint Genetic variants of GPX1 and SOD2 and breast cancer risk at the Ontario site of the Breast Cancer Family Registry
    Julia A Knight
    Division of Epidemiology and Biostatistics, Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, Ontario, Canada
    Cancer Epidemiol Biomarkers Prev 13:146-9. 2004
    ..30 for carriers versus noncarriers). There is a significant trend of increasing risk with increasing number of alleles with four GCG repeats (P = 0.03). This variant has not previously been reported to be associated with breast cancer...
  34. pmc A cross-sectional study of different patterns of oral contraceptive use among premenopausal women and circulating IGF-1: implications for disease risk
    Kristina M Blackmore
    Prosserman Center for Health Research, Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, Canada
    BMC Womens Health 11:15. 2011
    ..Understanding the effects of different patterns of OC use on IGF-1 levels may offer insight into its influence on disease risk in young women...
  35. ncbi request reprint ADH3 genotype, alcohol intake and breast cancer risk
    Mary Beth Terry
    Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY 10032, USA, and Prosserman Centre for Health Research, Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, Canada
    Carcinogenesis 27:840-7. 2006
    ..9, 95 % CI=1.2-7.1; postmenopausal women OR=1.8, 95% CI=0.9-3.8). These population-based data support the hypothesis that fast metabolizers of alcohol have a higher risk of breast cancer risk, from alcohol intake than slow metabolizers...
  36. ncbi request reprint Impact of familial risk and mammography screening on prognostic indicators of breast disease among women from the Ontario site of the Breast Cancer Family Registry
    Meghan J Walker
    Division of Prevention and Cancer Control, Cancer Care Ontario, 620 University Avenue, Toronto, ON, M5G 2L7, Canada
    Fam Cancer 13:163-72. 2014
    ..80, 95 % CI 1.18-51.50) compared with screen-detected cancers. Screening mammography may be effective for women with a first-degree family history of breast cancer, irrespective of level of familial risk...
  37. ncbi request reprint Does perceived risk predict breast cancer screening use? Findings from a prospective cohort study of female relatives from the Ontario site of the Breast Cancer Family Registry
    Meghan J Walker
    Prevention and Cancer Control, Cancer Care Ontario, Toronto, Ontario, Canada Division of Epidemiology, Dalla Lana School of Public Health, Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada Electronic address
    Breast 23:482-8. 2014
    ..Results may inform risk education and management strategies for women with varying levels of familial breast cancer risk. ..
  38. pmc Genetic variants in vitamin d pathway genes and risk of pancreas cancer; results from a population-based case-control study in ontario, Canada
    Laura N Anderson
    Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, Ontario, Canada
    PLoS ONE 8:e66768. 2013
    ..Vitamin D pathway gene variants may be associated with pancreas cancer risk and future studies are needed to understand the possible role of vitamin D in tumorigenesis and may have implications for cancer-prevention strategies. ..
  39. pmc Identification of germline alterations of the mad homology 2 domain of SMAD3 and SMAD4 from the Ontario site of the breast cancer family registry (CFR)
    Eric Tram
    Fred A, Litwin Centre for Cancer Genetics, Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Department of Laboratory Medicine and Pathobiology, University of Toronto, 60 Murray St, Toronto, ON M5T 3L9, Canada
    Breast Cancer Res 13:R77. 2011
    ..Thus, it is currently unknown whether germline SMAD3 and SMAD4 mutations are involved in breast cancer predisposition...
  40. pmc Worry is good for breast cancer screening: a study of female relatives from the ontario site of the breast cancer family registry
    Li Rita Zhang
    Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, ON, Canada M5T 3L9
    J Cancer Epidemiol 2012:545062. 2012
    ..Conclusions. Medium levels of cancer worries predicted higher rates of screening mammography and CBE among high-risk women...
  41. ncbi request reprint Vitamin D-related genetic variants, interactions with vitamin D exposure, and breast cancer risk among Caucasian women in Ontario
    Laura N Anderson
    Prevention and Cancer Control, Cancer Care Ontario, Toronto, ON, Canada
    Cancer Epidemiol Biomarkers Prev 20:1708-17. 2011
    ..This study investigated if candidate gene variants in vitamin D pathways are associated with breast cancer risk, or modify the associations between breast cancer and vitamin D exposure...
  42. ncbi request reprint Polymorphisms XRCC1-R399Q and XRCC3-T241M and the risk of breast cancer at the Ontario site of the Breast Cancer Family Registry
    Jane C Figueiredo
    Fred A Litwin Centre for Cancer Genetics, Samuel Lunenfeld Research Institute, Mount Sinai Hospital, 600 University Avenue, Toronto, Ontario M5G 1X5, Canada
    Cancer Epidemiol Biomarkers Prev 13:583-91. 2004
    ..Our results suggest that these polymorphisms may influence breast cancer risk by modifying the effect of risk factors such as FH. There is a need for further study into the role of these polymorphisms as effect modifiers...
  43. pmc Promoter methylation of Wnt antagonists DKK1 and SFRP1 is associated with opposing tumor subtypes in two large populations of colorectal cancer patients
    James B Rawson
    Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada
    Carcinogenesis 32:741-7. 2011
    ..This is the first large study to identify associations between Wnt antagonist promoter hypermethylation and CRC MSI subtype. These events provide insight into subtype-specific epigenetic mediation of Wnt signaling in CRC...
  44. doi request reprint Association between transillumination breast spectroscopy and quantitative mammographic features of the breast
    Kristina M Blackmore
    Samuel Lunenfeld Research Institute, Mount Sinai Hospital, 60 Murray Street, Box 18, Toronto, Ontario, Canada M5T 3L9
    Cancer Epidemiol Biomarkers Prev 17:1043-50. 2008
    ..41 and rt4 = -0.36). Given the association with quantitative mammographic features and tissue changes related to age and menopause, TiBS scores may prove useful as intermediate markers in studies of breast cancer etiology and prevention...
  45. pmc Solar ultraviolet-B radiation and vitamin D: a cross-sectional population-based study using data from the 2007 to 2009 Canadian Health Measures Survey
    Jamie A Greenfield
    Office of Biotechnology, Genomics and Population Health, Public Health Agency of Canada, 180 Queen Street West, Toronto, Canada
    BMC Public Health 12:660. 2012
    ..The purpose of this study was to measure the association between ground-level solar UV-B and serum concentrations of 25-hydroxyvitamin D (25(OH)D) using a secondary analysis of the 2007 to 2009 Canadian Health Measures Survey (CHMS)...
  46. ncbi request reprint Light and exercise and melatonin production in women
    Julia A Knight
    Prosserman Centre for Health Research, Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, Ontario, Canada
    Am J Epidemiol 162:1114-22. 2005
    ..It is possible that the protective effect of exercise with respect to breast cancer may operate in part through an effect on melatonin...
  47. ncbi request reprint Vitamin D intake from food and supplements among Ontario women based on the US block food frequency questionnaire with and without modification for Canadian food values
    Laura N Anderson
    Dalla Lana School of Public Health, University of Toronto, Toronto, ON
    Can J Public Health 101:318-21. 2010
    ..To measure and compare dietary vitamin D intake among women in Ontario using a modified Block 1998 (US) food frequency questionnaire (FFQ) before and after modification for Canadian-specific vitamin D food fortification...
  48. ncbi request reprint HER-2/neu status and tumor morphology of invasive breast carcinomas in Ashkenazi women with known BRCA1 mutation status in the Ontario Familial Breast Cancer Registry
    Louise A Quenneville
    Department of Pathology and Laboratory Medicine, Mount Sinai Hospital, Toronto, Ontario, Canada
    Cancer 95:2068-75. 2002
    ..The Ontario Familial Breast Cancer Registry collects clinical and family history data in familial breast carcinoma cases, and unselected Ashkenazi breast carcinomas, and acts as a tumor tissue repository...
  49. pmc Association of vitamin D with insulin resistance and beta-cell dysfunction in subjects at risk for type 2 diabetes
    Sheena Kayaniyil
    Department of Nutritional Sciences, University of Toronto, Toronto, Ontario, Canada
    Diabetes Care 33:1379-81. 2010
    ..To examine cross-sectional associations of serum vitamin D [25-hydroxyvitamin D, 25(OH)D] concentration with insulin resistance (IR) and beta-cell dysfunction in 712 subjects at risk for type 2 diabetes...
  50. ncbi request reprint Comparison of self-reported lifetime sun exposure with two methods of cutaneous microtopography
    Lynn Weiler
    Department of Public Health Sciences, Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada
    Am J Epidemiol 165:222-30. 2007
    ..10). While the Beagley-Gibson method was associated with more variables than the skin line count method, both methods require further refinement before graded skin replicas can be recommended as a substitute for self-report measures...
  51. ncbi request reprint Accuracy of breast screening among women with and without a family history of breast and/or ovarian cancer
    Erika Halapy
    Division of Preventive Oncology, Cancer Care Ontario, 620 University Avenue, Toronto, Ontario M5G 2L7, Canada
    Breast Cancer Res Treat 90:299-305. 2005
    ..To compare interval cancer rates, sensitivity and specificity of breast cancer screening between women with moderate or strong family history and women without a family history...
  52. ncbi request reprint Characteristics associated with participation at various stages at the Ontario site of the cooperative family registry for breast cancer studies
    Julia A Knight
    Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, Ontario, Canada
    Ann Epidemiol 12:27-33. 2002
    ..Sampling is based on age and defined genetic risk criteria. The purpose of this analysis was to evaluate the representativeness of the respondents...