Catherijne Aj Knibbe

Summary

Publications

  1. ncbi request reprint [Individualized dosing guidelines for children]
    Catherijne A J Knibbe
    St Antonius Ziekenhuis, Afd Klinische Farmacie, Nieuwegein, The Netherlands
    Ned Tijdschr Geneeskd 157:A4214. 2013
  2. pmc A bodyweight-dependent allometric exponent for scaling clearance across the human life-span
    Chenguang Wang
    Division of Pharmacology, LACDR, Leiden University, Leiden, The Netherlands
    Pharm Res 29:1570-81. 2012
  3. ncbi request reprint Ontogeny of hepatic glucuronidation; methods and results
    Elke H J Krekels
    Division of Pharmacology, Leiden Amsterdam Center for Drug Research, Leiden, The Netherlands
    Curr Drug Metab 13:728-43. 2012
  4. pmc Systematic evaluation of the descriptive and predictive performance of paediatric morphine population models
    Elke H J Krekels
    Division of Pharmacology, Leiden Amsterdam Center for Drug Research, Leiden, The Netherlands
    Pharm Res 28:797-811. 2011
  5. pmc The role of population PK-PD modelling in paediatric clinical research
    Roosmarijn F W De Cock
    Division of Pharmacology, Leiden Amsterdam Centre for Drug Research, Leiden University, Leiden, The Netherlands
    Eur J Clin Pharmacol 67:5-16. 2011
  6. doi request reprint Individualized dosing regimens in children based on population PKPD modelling: are we ready for it?
    Catherijne A J Knibbe
    Department of Clinical Pharmacy, St Antonius Hospital, Nieuwegein, The Netherlands
    Int J Pharm 415:9-14. 2011
  7. doi request reprint Morphine glucuronidation in preterm neonates, infants and children younger than 3 years
    Catherijne A J Knibbe
    Department of Clinical Pharmacy, St Antonius Hospital, 3430 EM Nieuwegein, The Netherlands
    Clin Pharmacokinet 48:371-85. 2009
  8. doi request reprint Advances in paediatric pharmacokinetics
    Catherijne A J Knibbe
    University of Leiden, Leiden Amsterdam Center for Drug Research, Division of Pharmacology, Leiden, The Netherlands
    Expert Opin Drug Metab Toxicol 7:1-8. 2011
  9. doi request reprint The use of the Behavioral Pain Scale to assess pain in conscious sedated patients
    Sabine J G M Ahlers
    Department of Clinical Pharmacy, St Antonius Hospital, PO Box 2500, 3440 EM Nieuwegein, The Netherlands
    Anesth Analg 110:127-33. 2010
  10. doi request reprint Prediction of propofol clearance in children from an allometric model developed in rats, children and adults versus a 0.75 fixed-exponent allometric model
    Mariska Y M Peeters
    Department of Clinical Pharmacy, St Antonius Hospital, Nieuwegein, The Netherlands
    Clin Pharmacokinet 49:269-75. 2010

Collaborators

Detail Information

Publications15

  1. ncbi request reprint [Individualized dosing guidelines for children]
    Catherijne A J Knibbe
    St Antonius Ziekenhuis, Afd Klinische Farmacie, Nieuwegein, The Netherlands
    Ned Tijdschr Geneeskd 157:A4214. 2013
    ..Drugs that serve as a model for a specific elimination route provide the basis for individualized dosing guidelines for children...
  2. pmc A bodyweight-dependent allometric exponent for scaling clearance across the human life-span
    Chenguang Wang
    Division of Pharmacology, LACDR, Leiden University, Leiden, The Netherlands
    Pharm Res 29:1570-81. 2012
    ..To explore different allometric equations for scaling clearance across the human life-span using propofol as a model drug...
  3. ncbi request reprint Ontogeny of hepatic glucuronidation; methods and results
    Elke H J Krekels
    Division of Pharmacology, Leiden Amsterdam Center for Drug Research, Leiden, The Netherlands
    Curr Drug Metab 13:728-43. 2012
    ....
  4. pmc Systematic evaluation of the descriptive and predictive performance of paediatric morphine population models
    Elke H J Krekels
    Division of Pharmacology, Leiden Amsterdam Center for Drug Research, Leiden, The Netherlands
    Pharm Res 28:797-811. 2011
    ..One covariate model was based on a systematic covariate analysis, the other on fixed allometric scaling principles...
  5. pmc The role of population PK-PD modelling in paediatric clinical research
    Roosmarijn F W De Cock
    Division of Pharmacology, Leiden Amsterdam Centre for Drug Research, Leiden University, Leiden, The Netherlands
    Eur J Clin Pharmacol 67:5-16. 2011
    ..This methodology will improve the efficacy/safety balance of dosing guidelines, which will be of benefit to the individual child...
  6. doi request reprint Individualized dosing regimens in children based on population PKPD modelling: are we ready for it?
    Catherijne A J Knibbe
    Department of Clinical Pharmacy, St Antonius Hospital, Nieuwegein, The Netherlands
    Int J Pharm 415:9-14. 2011
    ..In conclusion, PKPD modelling and simulation studies are important to develop evidence-based and individualized dosing schemes for children, with the ultimate goal to improve drug safety and efficacy in this population...
  7. doi request reprint Morphine glucuronidation in preterm neonates, infants and children younger than 3 years
    Catherijne A J Knibbe
    Department of Clinical Pharmacy, St Antonius Hospital, 3430 EM Nieuwegein, The Netherlands
    Clin Pharmacokinet 48:371-85. 2009
    ....
  8. doi request reprint Advances in paediatric pharmacokinetics
    Catherijne A J Knibbe
    University of Leiden, Leiden Amsterdam Center for Drug Research, Division of Pharmacology, Leiden, The Netherlands
    Expert Opin Drug Metab Toxicol 7:1-8. 2011
    ..Even though pharmacokinetic and pharmacodynamic relations determine together the optimal drug dose, age-related changes in pharmacokinetics have proven of utmost importance for optimising drug dosing in children...
  9. doi request reprint The use of the Behavioral Pain Scale to assess pain in conscious sedated patients
    Sabine J G M Ahlers
    Department of Clinical Pharmacy, St Antonius Hospital, PO Box 2500, 3440 EM Nieuwegein, The Netherlands
    Anesth Analg 110:127-33. 2010
    ..Additionally, in conscious sedated patients, the combination of the BPS and the patient-rated Verbal Rating Scale (VRS-4) was evaluated...
  10. doi request reprint Prediction of propofol clearance in children from an allometric model developed in rats, children and adults versus a 0.75 fixed-exponent allometric model
    Mariska Y M Peeters
    Department of Clinical Pharmacy, St Antonius Hospital, Nieuwegein, The Netherlands
    Clin Pharmacokinet 49:269-75. 2010
    ..Both allometric models based on bodyweight alone may be of use to predict propofol clearance in individuals older than 2 years. Approaches that also incorporate maturation are required to predict clearance under the age of 2 years...
  11. pmc Comparison of different pain scoring systems in critically ill patients in a general ICU
    Sabine J G M Ahlers
    Department of Anaesthesiology and Intensive Care, St Antonius Hospital, Koekoekslaan 1, Nieuwegein, 3440 EM, The Netherlands
    Crit Care 12:R15. 2008
    ....
  12. ncbi request reprint Propofol pharmacokinetics and pharmacodynamics for depth of sedation in nonventilated infants after major craniofacial surgery
    Mariska Y M Peeters
    Department of Clinical Pharmacy, St Antonius Hospital, Nieuwegein, The Netherlands
    Anesthesiology 104:466-74. 2006
    ..To support safe and effective use of propofol in nonventilated children after major surgery, a model for propofol pharmacokinetics and pharmacodynamics is described...
  13. ncbi request reprint Pharmacokinetics and pharmacodynamics of midazolam and metabolites in nonventilated infants after craniofacial surgery
    Mariska Y M Peeters
    Department of Clinical Pharmacy, St Antonius Hospital, The Netherlands
    Anesthesiology 105:1135-46. 2006
    ..Because information on the optimal dose of midazolam for sedation of nonventilated infants after major surgery is scant, a population pharmacokinetic and pharmacodynamic model is developed for this specific group...
  14. ncbi request reprint Population pharmacokinetic and pharmacodynamic modeling of propofol for long-term sedation in critically ill patients: a comparison between propofol 6% and propofol 1%
    Catherijne A J Knibbe
    Department of Clinical Pharmacy, St Antonius Hospital, Nieuwegein, The Netherlands
    Clin Pharmacol Ther 72:670-84. 2002
    ..In the models the influence of time-independent covariates, in particular, the propofol formulation (propofol 6% versus propofol 1%), and of time-dependent covariates was investigated...
  15. pmc Pharmacokinetics and effects of propofol 6% for short-term sedation in paediatric patients following cardiac surgery
    Catherijne A J Knibbe
    Department of Clinical Pharmacy, St Antonius Hospital, PO Box 2500, 3430 EM Nieuwegein, The Netherlands
    Br J Clin Pharmacol 54:415-22. 2002
    ..This paper describes the pharmacokinetics and effects of propofol in short-term sedated paediatric patients...