K J Klos

Summary

Publications

  1. ncbi request reprint Pathological hypersexuality predominantly linked to adjuvant dopamine agonist therapy in Parkinson's disease and multiple system atrophy
    Kevin J Klos
    Department of Neurology, Division of Movement Disorders, Mayo Clinic, Rochester, MN 55905, USA
    Parkinsonism Relat Disord 11:381-6. 2005
  2. ncbi request reprint Brain metal concentrations in chronic liver failure patients with pallidal T1 MRI hyperintensity
    K J Klos
    Department of Neurology, Mayo Clinic, Rochester, MN, USA
    Neurology 67:1984-9. 2006
  3. ncbi request reprint Neuropsychological profiles of manganese neurotoxicity
    K J Klos
    Department of Neurology, Mayo Clinic, Rochester, MN, USA
    Eur J Neurol 13:1139-41. 2006
  4. ncbi request reprint Neurologic manifestations in welders with pallidal MRI T1 hyperintensity
    K A Josephs
    Department of Neurology, Mayo Clinic, Rochester, MN 55905, USA
    Neurology 64:2033-9. 2005
  5. ncbi request reprint Alpha-synuclein pathology in the spinal cords of neurologically asymptomatic aged individuals
    K J Klos
    Department of Neurology, Mayo Clinic, Rochester, MN, USA
    Neurology 66:1100-2. 2006
  6. ncbi request reprint Pathological gambling caused by drugs used to treat Parkinson disease
    M Leann Dodd
    Department of Psychiatry and Psychology, Mayo Clinic, Rochester, MN 55905, USA
    Arch Neurol 62:1377-81. 2005
  7. ncbi request reprint Unusual compulsive behaviors primarily related to dopamine agonist therapy in Parkinson's disease and multiple system atrophy
    Andrew McKeon
    Department of Neurology, Mayo Clinic, 200 1st St SW, Rochester, MN 55905, USA
    Parkinsonism Relat Disord 13:516-9. 2007
  8. doi request reprint Cardiac sympathetic denervation correlates with clinical and pathologic stages of Parkinson's disease
    Hiroshige Fujishiro
    Department of Pathology Neuropathology, Mayo Clinic, Jacksonville, Florida, USA
    Mov Disord 23:1085-92. 2008
  9. doi request reprint Evidence that incidental Lewy body disease is pre-symptomatic Parkinson's disease
    Dennis W Dickson
    Neuropathology Laboratory, Department of Neuroscience, Mayo Clinic, 4500 San Pablo Road, Jacksonville, FL 32224, USA
    Acta Neuropathol 115:437-44. 2008
  10. ncbi request reprint Early-onset familial parkinsonism due to POLG mutations
    Guido Davidzon
    Department of Neurology, Columbia University Medical Center, New York, NY 10032, USA
    Ann Neurol 59:859-62. 2006

Collaborators

Detail Information

Publications13

  1. ncbi request reprint Pathological hypersexuality predominantly linked to adjuvant dopamine agonist therapy in Parkinson's disease and multiple system atrophy
    Kevin J Klos
    Department of Neurology, Division of Movement Disorders, Mayo Clinic, Rochester, MN 55905, USA
    Parkinsonism Relat Disord 11:381-6. 2005
    ..A systematic literature review of pathological hypersexuality in PD revealed similar medication histories; combining these cases with our series, 26 of 29 patients (90%) were on adjuvant dopamine agonists...
  2. ncbi request reprint Brain metal concentrations in chronic liver failure patients with pallidal T1 MRI hyperintensity
    K J Klos
    Department of Neurology, Mayo Clinic, Rochester, MN, USA
    Neurology 67:1984-9. 2006
    ..Manganese accumulation may be responsible for the imaging and clinical findings...
  3. ncbi request reprint Neuropsychological profiles of manganese neurotoxicity
    K J Klos
    Department of Neurology, Mayo Clinic, Rochester, MN, USA
    Eur J Neurol 13:1139-41. 2006
    ..Across all three groups, the neuropsychological profiles suggest frontal and subcortical cognitive impairment, with more widespread abnormalities occurring in the non-welding groups...
  4. ncbi request reprint Neurologic manifestations in welders with pallidal MRI T1 hyperintensity
    K A Josephs
    Department of Neurology, Mayo Clinic, Rochester, MN 55905, USA
    Neurology 64:2033-9. 2005
    ..Increased T1 MRI signal in the basal ganglia is a biologic marker of manganese accumulation. Recent studies have associated welding and parkinsonism, but generally without MRI corroboration...
  5. ncbi request reprint Alpha-synuclein pathology in the spinal cords of neurologically asymptomatic aged individuals
    K J Klos
    Department of Neurology, Mayo Clinic, Rochester, MN, USA
    Neurology 66:1100-2. 2006
    ..Sparse alpha-synuclein pathology was also detected in the substantia nigra, basal forebrain, amygdala, or cortex in all but two cases...
  6. ncbi request reprint Pathological gambling caused by drugs used to treat Parkinson disease
    M Leann Dodd
    Department of Psychiatry and Psychology, Mayo Clinic, Rochester, MN 55905, USA
    Arch Neurol 62:1377-81. 2005
    ..Pathological gambling is a rare potential complication related to treatment of Parkinson disease (PD). However, the etiology of this behavior is poorly understood...
  7. ncbi request reprint Unusual compulsive behaviors primarily related to dopamine agonist therapy in Parkinson's disease and multiple system atrophy
    Andrew McKeon
    Department of Neurology, Mayo Clinic, 200 1st St SW, Rochester, MN 55905, USA
    Parkinsonism Relat Disord 13:516-9. 2007
    ....
  8. doi request reprint Cardiac sympathetic denervation correlates with clinical and pathologic stages of Parkinson's disease
    Hiroshige Fujishiro
    Department of Pathology Neuropathology, Mayo Clinic, Jacksonville, Florida, USA
    Mov Disord 23:1085-92. 2008
    ..42, P < 0.05). This study demonstrates that cardiac sympathetic degeneration and alpha-synuclein pathology is present in presymptomatic phase of PD, and that both increase with disease duration and severity...
  9. doi request reprint Evidence that incidental Lewy body disease is pre-symptomatic Parkinson's disease
    Dennis W Dickson
    Neuropathology Laboratory, Department of Neuroscience, Mayo Clinic, 4500 San Pablo Road, Jacksonville, FL 32224, USA
    Acta Neuropathol 115:437-44. 2008
    ..The findings suggest that iLBD is preclinical PD and that the lack of symptoms is due to subthreshold pathology...
  10. ncbi request reprint Early-onset familial parkinsonism due to POLG mutations
    Guido Davidzon
    Department of Neurology, Columbia University Medical Center, New York, NY 10032, USA
    Ann Neurol 59:859-62. 2006
    ..To define the molecular etiology of early-onset parkinsonism and peripheral neuropathy...
  11. ncbi request reprint Neurologic spectrum of chronic liver failure and basal ganglia T1 hyperintensity on magnetic resonance imaging: probable manganese neurotoxicity
    Kevin J Klos
    Department of Neurology, Mayo Clinic, Rochester, MN 55905, USA
    Arch Neurol 62:1385-90. 2005
    ..The magnetic resonance imaging signal changes are characteristic of manganese accumulation, which has been neuropathologically confirmed. Manganese neurotoxicity may result in additional neurologic findings besides parkinsonism...
  12. ncbi request reprint Alpha-synuclein immunohistochemistry in two cases of co-occurring idiopathic Parkinson's disease and motor neuron disease
    Kevin J Klos
    Department of Neurology, Movement Disorder Division, Mayo Clinic, Rochester, Minnesota, USA
    Mov Disord 20:1515-20. 2005
    ..We compared our two cases to all previously published pathological cases of combined LBD and motor neuron degeneration...
  13. doi request reprint Incidental Lewy body disease and preclinical Parkinson disease
    Anthony DelleDonne
    Department of Neuroscience, Mayo Clinic, Jacksonville, FL 32224, USA
    Arch Neurol 65:1074-80. 2008
    ..The significance of Lewy bodies detected at autopsy in the brains of clinically normal individuals is uncertain but may represent preclinical Parkinson disease (PD)...