Adam Kirton

Summary

Publications

  1. ncbi request reprint Parent and family impact of raising a child with perinatal stroke
    Taryn B Bemister
    Calgary Pediatric Stroke Program, Room C1 320, Alberta Children s Hospital, 2888 Shaganappi Trail NW, Calgary, AB T3B 6A8, Canada
    BMC Pediatr 14:182. 2014
  2. doi request reprint Can noninvasive brain stimulation measure and modulate developmental plasticity to improve function in stroke-induced cerebral palsy?
    Adam Kirton
    Calgary Pediatric Stroke Program, Alberta Children s Hospital Research Institute, Section of Neurology, Department of Pediatrics, University of Calgary, Calgary, Alberta, Canada
    Semin Pediatr Neurol 20:116-26. 2013
  3. doi request reprint Fibromuscular dysplasia and childhood stroke
    Adam Kirton
    Calgary Paediatric Stroke Program, Section of Neurology, Alberta Children s Hospital Research Institute, University of Calgary, Calgary, AB, Canada
    Brain 136:1846-56. 2013
  4. doi request reprint Modeling developmental plasticity after perinatal stroke: defining central therapeutic targets in cerebral palsy
    Adam Kirton
    Calgary Pediatric Stroke Program, Alberta Children s Hospital Research Institute, and Section of Neurology, Department of Pediatrics and Department of Clinical Neurosciences, University of Calgary, Calgary, Alberta, Canada
    Pediatr Neurol 48:81-94. 2013
  5. doi request reprint Symptomatic neonatal arterial ischemic stroke: the International Pediatric Stroke Study
    Adam Kirton
    Alberta Children s Hospital, Calgary, Alberta, Canada
    Pediatrics 128:e1402-10. 2011
  6. doi request reprint Risk factors and presentations of periventricular venous infarction vs arterial presumed perinatal ischemic stroke
    Adam Kirton
    Department of Pediatrics, Alberta Children s Hospital, University of Calgary, Canada
    Arch Neurol 67:842-8. 2010
  7. doi request reprint Cortical excitability and interhemispheric inhibition after subcortical pediatric stroke: plastic organization and effects of rTMS
    Adam Kirton
    Department of Pediatrics, University of Calgary, Calgary, Alta, Canada Department of Clinical Neurosciences, University of Calgary, Calgary, Alta, Canada
    Clin Neurophysiol 121:1922-9. 2010
  8. doi request reprint Contralesional repetitive transcranial magnetic stimulation for chronic hemiparesis in subcortical paediatric stroke: a randomised trial
    Adam Kirton
    Division of Neurology, Department of Pediatrics, Alberta Children s Hospital, University of Calgary, Calgary, Canada
    Lancet Neurol 7:507-13. 2008
  9. ncbi request reprint Safety of anticoagulants in children with arterial ischemic stroke
    Tal Schechter
    Division of Hematology Oncology, Department of Pediatrics, The Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada
    Blood 119:949-56. 2012
  10. doi request reprint Cerebellar atrophy in childhood arterial ischemic stroke: acute diffusion MRI biomarkers
    Sarah Mah
    University of Calgary, Calgary, Alberta, Canada
    Stroke 44:2468-74. 2013

Collaborators

Detail Information

Publications25

  1. ncbi request reprint Parent and family impact of raising a child with perinatal stroke
    Taryn B Bemister
    Calgary Pediatric Stroke Program, Room C1 320, Alberta Children s Hospital, 2888 Shaganappi Trail NW, Calgary, AB T3B 6A8, Canada
    BMC Pediatr 14:182. 2014
    ..A secondary aim was to examine how caring for a child with perinatal stroke differentially affects mothers and fathers...
  2. doi request reprint Can noninvasive brain stimulation measure and modulate developmental plasticity to improve function in stroke-induced cerebral palsy?
    Adam Kirton
    Calgary Pediatric Stroke Program, Alberta Children s Hospital Research Institute, Section of Neurology, Department of Pediatrics, University of Calgary, Calgary, Alberta, Canada
    Semin Pediatr Neurol 20:116-26. 2013
    ..In this article, how potential central therapeutic targets are identified and potentially modulated to enhance motor function within these models is discussed. Also, future directions and emerging clinical trials are reviewed. ..
  3. doi request reprint Fibromuscular dysplasia and childhood stroke
    Adam Kirton
    Calgary Paediatric Stroke Program, Section of Neurology, Alberta Children s Hospital Research Institute, University of Calgary, Calgary, AB, Canada
    Brain 136:1846-56. 2013
    ..Intimal fibroplasia predominates while 'string of beads' angiography is rare. Accurate clinical diagnosis is currently challenging...
  4. doi request reprint Modeling developmental plasticity after perinatal stroke: defining central therapeutic targets in cerebral palsy
    Adam Kirton
    Calgary Pediatric Stroke Program, Alberta Children s Hospital Research Institute, and Section of Neurology, Department of Pediatrics and Department of Clinical Neurosciences, University of Calgary, Calgary, Alberta, Canada
    Pediatr Neurol 48:81-94. 2013
    ..The means to measure and modulate these targets, including evidence-based rehabilitation therapies and noninvasive brain stimulation, are suggested. Implications for clinical trials and future directions are discussed...
  5. doi request reprint Symptomatic neonatal arterial ischemic stroke: the International Pediatric Stroke Study
    Adam Kirton
    Alberta Children s Hospital, Calgary, Alberta, Canada
    Pediatrics 128:e1402-10. 2011
    ..Multicenter studies must define epidemiology, risk factors, treatment practices, and outcomes to advance clinical trials and improve the adverse outcomes suffered by most survivors...
  6. doi request reprint Risk factors and presentations of periventricular venous infarction vs arterial presumed perinatal ischemic stroke
    Adam Kirton
    Department of Pediatrics, Alberta Children s Hospital, University of Calgary, Canada
    Arch Neurol 67:842-8. 2010
    ..To determine whether clinical presentations and risk factor profiles differ between periventricular venous infarction (PVI) and arterial presumed perinatal ischemic stroke (APPIS)...
  7. doi request reprint Cortical excitability and interhemispheric inhibition after subcortical pediatric stroke: plastic organization and effects of rTMS
    Adam Kirton
    Department of Pediatrics, University of Calgary, Calgary, Alta, Canada Department of Clinical Neurosciences, University of Calgary, Calgary, Alta, Canada
    Clin Neurophysiol 121:1922-9. 2010
    ..Imbalance of interhemispheric inhibition (IHI) in adult subcortical stroke is a therapeutic target. We hypothesized that IHI imbalance occurs in childhood AIS and is modifiable by rTMS...
  8. doi request reprint Contralesional repetitive transcranial magnetic stimulation for chronic hemiparesis in subcortical paediatric stroke: a randomised trial
    Adam Kirton
    Division of Neurology, Department of Pediatrics, Alberta Children s Hospital, University of Calgary, Calgary, Canada
    Lancet Neurol 7:507-13. 2008
    ..We aimed to test whether contralesional, inhibitory repetitive transcranial magnetic stimulation (rTMS) could affect interhemispheric inhibition to improve hand function in chronic subcortical paediatric AIS...
  9. ncbi request reprint Safety of anticoagulants in children with arterial ischemic stroke
    Tal Schechter
    Division of Hematology Oncology, Department of Pediatrics, The Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada
    Blood 119:949-56. 2012
    ..3507). We conclude that ACT is relatively safe in children with AIS, with a 4% risk of symptomatic ICH. Based on the safety of ACT in our study, clinical trials of ACT in childhood AIS are warranted...
  10. doi request reprint Cerebellar atrophy in childhood arterial ischemic stroke: acute diffusion MRI biomarkers
    Sarah Mah
    University of Calgary, Calgary, Alberta, Canada
    Stroke 44:2468-74. 2013
    ..We hypothesized that cerebellar atrophy can be quantified on clinical neuroimaging in childhood arterial ischemic stroke and is predicted by contralesional CST-DWI...
  11. doi request reprint Low detection rate of craniocervical arterial dissection in children using time-of-flight magnetic resonance angiography: causes and strategies to improve diagnosis
    Marilyn A Tan
    Section of Neurology, Department of Pediatrics, Philippine General Hospital, Manila, Philippines
    J Child Neurol 24:1250-7. 2009
    ..If suspicion for arterial dissection is high, T1 fat-saturated neck imaging and contrast-enhanced magnetic resonance angiography should be considered to maximize detection...
  12. doi request reprint Mechanisms of pediatric cerebral arteriopathy: an inflammatory debate
    Aleksandra Mineyko
    Calgary Pediatric Stroke Program, Section of Neurology, Department of Pediatrics, Alberta Children s Hospital Research Institute, Calgary, Alberta, Canada
    Pediatr Neurol 48:14-23. 2013
    ..Recent advances and future research directions, including biomarker, neuroimaging, and pathologic approaches and how they might address these important clinical questions, are discussed...
  13. ncbi request reprint Presumed perinatal ischemic stroke: vascular classification predicts outcomes
    Adam Kirton
    Division of Neurology, Alberta Children s Hospital, University of Calgary, Calgary, Alberta, Canada
    Ann Neurol 63:436-43. 2008
    ..Using the largest published cohort, we aimed to define arterial and PVI PPIS syndromes and their outcomes...
  14. ncbi request reprint Neurocardiogenic syncope complicating pediatric transcranial magnetic stimulation
    Adam Kirton
    Division of Neurology, Alberta Children s Hospital, University of Calgary, Calgary, Alberta, Canada
    Pediatr Neurol 39:196-7. 2008
    ....
  15. doi request reprint Normal intracranial periarterial enhancement on pediatric brain MR imaging
    Aleksandra Mineyko
    Section of Neurology, Department of Pediatrics, Alberta Children s Hospital Research Institute, Calgary, Alberta, Canada
    Neuroradiology 55:1161-9. 2013
    ..The aim was to describe normal periarterial enhancement in the pediatric population...
  16. doi request reprint Reduced ipsilesional cortical volumes in fetal periventricular venous infarction
    Damon Li
    Alberta Children s Hospital, Calgary, Canada
    Stroke 43:1404-7. 2012
    ..However, cognitive, language, and behavioral deficits also occur. We hypothesized that ipsilesional cortical gray matter volumes are reduced in PVI...
  17. doi request reprint Advances in perinatal ischemic stroke
    Adam Kirton
    Division of Neurology, Alberta Children s Hospital, Calgary, Alberta, Canada
    Pediatr Neurol 40:205-14. 2009
    ..The adverse outcomes suffered by most children highlight the need for further research. Reviewed here are the current understandings, recent advancements, and future directions for research in perinatal ischemic stroke...
  18. doi request reprint Sagittal sinus compression is associated with neonatal cerebral sinovenous thrombosis
    Marilyn Tan
    Calgary Pediatric Stroke Program, Calgary, Alberta, Canada
    Pediatrics 128:e429-35. 2011
    ..Newborns frequently incur positional occipital bone compression of the superior sagittal sinus (SSS). We hypothesized that SSS compression is associated with neonatal CSVT...
  19. ncbi request reprint TMS neuro-cardiovascular coupling in vascular compression cranial neuropathy
    Adam Kirton
    Division of Neurology, Alberta Children s Hospital, University of Calgary, Calgary, Alberta, Canada
    Can J Neurol Sci 36:83-8. 2009
    ..We hypothesized that the arterial pressure wave (APW) would interact at the neurovascular interface in NVC to inhibit transmission of transcranial magnetic stimulation (TMS) stimuli to affected muscles...
  20. ncbi request reprint Development, reliability, and validity of the Alberta Perinatal Stroke Project Parental Outcome Measure
    Taryn B Bemister
    Department of Psychology, University of Calgary, Calgary, Alberta, Canada Alberta Children s Hospital Research Institute, University of Calgary, Calgary, Alberta, Canada
    Pediatr Neurol 51:43-52. 2014
    ..The Alberta Perinatal Stroke Project Parental Outcome Measure was developed as a 26-item questionnaire on the impact of perinatal stroke on parents and families...
  21. pmc Emergence of the primary pediatric stroke center: impact of the thrombolysis in pediatric stroke trial
    Timothy J Bernard
    From the Department of Neurology, Children s Hospital Colorado, Aurora T J B Departments of Neurology, Psychiatry and Radiology, Boston Children s Hospital, MA M J R Department of Neurology, Hospital for Sick Children, Toronto, Ontario, Canada G d V, Department of Neurology, Alberta Children s Hospital Research Institute, University of Calgary, Calgary, AB, Canada A K Department of Pediatrics, Medical College of Wisconsin, Milwaukee, and BloodCenter of Wisconsin J C G Department of Pediatrics, McMaster University, Hamilton, Ontario, Canada A K C Department of Pediatrics, Dell Children s Medical Center, Austin, TX C A H, Department of Neurology, University of Pennsylvania School of Medicine, Philadelphia R N I Department of Neurology, Memorial Hermann Hospital, Houston, TX J C G Division of Pediatric Neurology, Vanderbilt University, Nashville, TN L C J Department of Neurology, Primary Children s Medical Center, Salt Lake City, UT S B Department of Neurology, Cleveland Clinic, OH N R F Department of Pediatrics and Neurology, UT Southwestern Medical Center, Dallas TX M M D Department of Neurology, Stanford University
    Stroke 45:2018-23. 2014
    ..We describe the development of primary pediatric stroke centers through preparation of participating centers in the Thrombolysis in Pediatric Stroke (TIPS) trial...
  22. ncbi request reprint A review of cognitive outcomes in children following perinatal stroke
    Kara Murias
    a Neurolab, Departments of Psychology and Clinical Neurosciences, Hotchkiss Brain Institute and Alberta Children s Hospital Research Institute, University of Calgary, Calgary, Canada
    Dev Neuropsychol 39:131-57. 2014
    ..Better understanding of the impact of early stroke has potential to elucidate processes of brain development, in addition to providing guidance for prognosis and rehabilitation. ..
  23. pmc The black box of perinatal ischemic stroke pathogenesis
    Aleksandra Mineyko
    The Division of Neurology, Department of Pediatrics, Alberta Children s Hospital, Calgary, Alberta, Canada
    J Child Neurol 26:1154-62. 2011
    ..This review summarizes current evidence and suggests future directions for research...
  24. doi request reprint Alpers syndrome: the natural history of a case highlighting neuroimaging, neuropathology, and fat metabolism
    Aneal Khan
    Departments of Pediatrics and Medical Genetics, University of Calgary, and Alberta Children s Hospital, Calgary, Alberta, Canada
    J Child Neurol 27:636-40. 2012
    ....
  25. ncbi request reprint Pediatric stroke: rehabilitation of focal injury in the developing brain
    Adam Kirton
    Division of Neurology, Alberta Children s Hospital, Calgary, AB, Canada T3B 6A8
    NeuroRehabilitation 22:371-82. 2007
    ..All aspects of a patient's function, from the physical to psychological, including issues unique to children and their families, must be addressed and are reviewed. New advances and future directions for research are highlighted...