Effects of glucan treatment on the Th1/Th2 balance in patients with allergic rhinitis: a double-blind placebo-controlled studyCengiz Kirmaz
Celal Bayar University Medical Faculty, Department of Internal Medicine, Division of Immunology and Allergy, Manisa, Turkey
Eur Cytokine Netw 16:128-34. 2005
..Beta-1,3-1,6-glucan (Glucan) is an immunomodulator stimulating particularly the antitumor response. An efficient antitumor stimulation can be achieved through a Th1-mediated immune response...
Sexual dysfunction in patients with allergic rhinoconjunctivitisCengiz Kirmaz
Division of Allergy and Immunology, Department of Internal Medicine, Celal Bayar University, Manisa, Turkey
Ann Allergy Asthma Immunol 95:525-9. 2005
..Allergic rhinoconjunctivitis (ARC) affects QoL, causing limitations in many areas. However, there has not been research on changes in sexual function in patients with ARC...
Effects of allergen-specific immunotherapy on functions of helper and regulatory T cells in patients with seasonal allergic rhinitisCengiz Kirmaz
Celal Bayar University, Medical Faculty, Department of Internal Medicine, Division of Immunology, Manisa
Eur Cytokine Netw 22:15-23. 2011
..However, there are few studies that evaluate the number and function of these cells in the inflammatory area after SIT treatment...
Lower respiratory tract complications during nasal provocation: nonspecific stimulant or specific allergen?Cengiz Kirmaz
Division of Allergy and Immunology, Department of Internal Medicine, Celal Bayar University Medical Faculty, Manisa, Turkey
Ann Allergy Asthma Immunol 98:524-32. 2007
..However, not enough research is available to demonstrate whether there is a response in the lower respiratory tract during nasal provocation tests (NPTs) performed to evaluate only nasal airway in these patients...
Regulatory-T, T-helper 1, and T-helper 2 cell differentiation in nasal mucosa of allergic rhinitis with olive pollen sensitivityAyhan Sogut
Pediatric Allergy and Pulmonology Unit, Celal Bayar University School of Medicine, Manisa, Turkey
Int Arch Allergy Immunol 157:349-53. 2012
..Allergic rhinitis (AR) is a disease in which T-helper (Th)2 response is predominant and its pathogenic mechanism is still poorly understood...
Is the menstrual cycle affecting the skin prick test reactivity?Cengiz Kirmaz
Department of Internal Medicine, Celal Bayar University, Manisa, Turkey
Asian Pac J Allergy Immunol 22:197-203. 2004
..Additionally, allergens seem to cause mast cell degranulation to a greater extent in subjects in which endogenous hormones like estradiol and LH are elevated...
Down-regulation of the auto-aggressive processes in patients with hypothyroid Hashimoto's thyroiditis following substitutive treatment with L-thyroxineFeyzullah Guclu
Celal Bayar University, Medical Faculty, Department of Internal Medicine, Division of Endocrinology, Manisa, Turkiye
Eur Cytokine Netw 20:27-32. 2009
..The pathogenesis of Hashimoto's thyroiditis involves a complex interaction between predisposing genetic and environmental factors...
Nasal mucosal expression of nitric oxide synthases in patients with allergic rhinitis and its relation to asthmaHasan Yuksel
Department of Pediatric Allergy and Pulmonology, Celal Bayar University, Manisa, Turkey
Ann Allergy Asthma Immunol 100:12-6. 2008
..Small amounts of NO produced by constitutive NO synthase (NOS) is anti-inflammatory, whereas large amounts produced by inducible NOS (iNOS) are proinflammatory...
Validity and reliability of the Turkish translation of the Pediatric Asthma Quality of Life QuestionnaireHasan Yuksel
Department of Pediatric Allergy and Pulmonology, Celal Bayar University Faculty of Medicine, Manisa, Turkey
Turk J Pediatr 51:154-60. 2009
..05 for all). Exploratory factor analysis revealed that 78.3% of the items were replaced in their original domain. This Turkish version of PAQLQ is a valid and reliable disease-specific health-related quality of life questionnaire...
Evaluation of sleep quality and anxiety-depression parameters in asthmatic children and their mothersHasan Yuksel
Department of Pediatric Allergy, School of Medicine, Celal Bayar University, Manisa, Turkey
Respir Med 101:2550-4. 2007
..The aim of this study was to evaluate sleep quality in asthmatic children and their mothers as well as the status of anxiety-depression in the mothers...
Sensitization to cat allergens in non-cat owner patients with respiratory allergyOkan Gulbahar
Departament of Internal Medicine, Division of Clinical Immunology and Allergy, Ege University Faculty of Medicine, 35100 Bornova Izmir, Turkey
Ann Allergy Asthma Immunol 90:635-9. 2003
..Cats represent one of the most important sources of indoor allergens. The sensitization rate can reach up to 60% in western countries. Keeping cats indoors is uncommon in big cities in Turkey, but cats living in the streets are common...
Increased expression of angiogenic markers in patients with seasonal allergic rhinitisCengiz Kirmaz
Celal Bayar University, Medical Faculty, Department of Internal Medicine, Division of Immunology, Manisa, Turkey
Eur Cytokine Netw 15:317-22. 2004
..Vascular endothelial growth factor (VEGF), CD34 and von Willebrand's factor (FvW) are known angiogenic markers. Angiogenesis and airway remodelling has been documented in asthma but not in allergic rhinitis...
Is pulmonary arterial pressure affected by allergic rhinitis with nasal obstruction?Papatya Bayrak
Division of Immunology and Allergy, Department of Internal Medicine, Celal Bayar University, Medical Faculty, Turkey
Asian Pac J Allergy Immunol 25:121-6. 2007
..Further studies with more cases are needed in order to determine the cardiac effects of hypoxia in AR, mainly pulmonary arterial hypertension...
Serum transforming growth factor-beta1(TGF-beta1) in patients with cirrhosis, chronic hepatitis B and chronic hepatitis C [corrected]Cengiz Kirmaz
Celal Bayar University, Medical Faculty, Department of Internal Medicine, Division of Immunology, Manisa, Turkey
Eur Cytokine Netw 15:112-6. 2004
..In conclusion, elevated TGF-beta1 levels in patients with CHC and cirrhosis may have a role in the pathogenesis and chronicity of these diseases...
Influence of the selective oestrogen receptor modulator (raloxifene hydrochloride) on IL-6, TNF-alpha, TGF-beta1 and bone turnover markers in the treatment of postmenopausal osteoporosisBilgin Ozmen
Celal Bayar University, Medical Faculty, Department of Internal Medicine, Division of Endocrinology and Metabolism, Manisa, Turkey
Eur Cytokine Netw 18:148-53. 2007
..However, there seems to be a paucity of in vivo research concerned with changes in these cytokines in osteoporosis...
Lung involvement in inflammatory bowel diseasesNurhan Sarioğlu
Ann Saudi Med 26:407-8. 2006