Michael S Kinch

Summary

Publications

  1. doi request reprint Function-first approaches to improve target identification in cancer
    Michael S Kinch
    Functional Genetics Inc, Gaithersburg, MD 20878, USA
    Future Oncol 5:617-23. 2009
  2. doi request reprint Development of a broad-spectrum antiviral with activity against Ebola virus
    M Javad Aman
    United States Army Medical Research Institute for Infectious Diseases, Fort Detrick, MD 21702, USA
    Antiviral Res 83:245-51. 2009
  3. ncbi request reprint Identification of annexin A13 as a regulator of chemotherapy resistance using random homozygous gene perturbation
    Heinz Reiske
    Functional Genetics, Inc, Gaithersburg, Maryland 20878, USA
    Anal Quant Cytol Histol 32:61-9. 2010
  4. pmc Identification of novel host-oriented targets for Human Immunodeficiency Virus type 1 using Random Homozygous Gene Perturbation
    Hanwen Mao
    Functional Genetics, Inc, Gaithersburg, MD 20878, USA
    Virol J 6:154. 2009
  5. pmc Antiviral activity of a small-molecule inhibitor of filovirus infection
    Travis K Warren
    US Army Medical Research Institute of Infectious Diseases, Fort Detrick, Frederick, Maryland, USA
    Antimicrob Agents Chemother 54:2152-9. 2010
  6. ncbi request reprint Selective targeting and potent control of tumor growth using an EphA2/CD3-Bispecific single-chain antibody construct
    Scott A Hammond
    MedImmune, Inc, Gaithersburg, Maryland 20878, USA
    Cancer Res 67:3927-35. 2007
  7. pmc The use of Random Homozygous Gene Perturbation to identify novel host-oriented targets for influenza
    Baoquan Sui
    Functional Genetics, Inc, Gaithersburg, MD 20878, USA
    Virology 387:473-81. 2009
  8. ncbi request reprint Direct targeting of alphavbeta3 integrin on tumor cells with a monoclonal antibody, Abegrin
    Kathy Mulgrew
    MedImmune, Inc, One MedImmune Way, Gaithersburg, MD 20878, USA
    Mol Cancer Ther 5:3122-9. 2006

Collaborators

Detail Information

Publications8

  1. doi request reprint Function-first approaches to improve target identification in cancer
    Michael S Kinch
    Functional Genetics Inc, Gaithersburg, MD 20878, USA
    Future Oncol 5:617-23. 2009
    ....
  2. doi request reprint Development of a broad-spectrum antiviral with activity against Ebola virus
    M Javad Aman
    United States Army Medical Research Institute for Infectious Diseases, Fort Detrick, MD 21702, USA
    Antiviral Res 83:245-51. 2009
    ..These findings suggest FGI-106 may provide an opportunity for targeting viral diseases...
  3. ncbi request reprint Identification of annexin A13 as a regulator of chemotherapy resistance using random homozygous gene perturbation
    Heinz Reiske
    Functional Genetics, Inc, Gaithersburg, Maryland 20878, USA
    Anal Quant Cytol Histol 32:61-9. 2010
    ..To utilize a powerful new technology for target discovery, Random Homozygous Gene Perturbation (RHGP), and to identify novel targets that cause tumor cells to become chemoresistant...
  4. pmc Identification of novel host-oriented targets for Human Immunodeficiency Virus type 1 using Random Homozygous Gene Perturbation
    Hanwen Mao
    Functional Genetics, Inc, Gaithersburg, MD 20878, USA
    Virol J 6:154. 2009
    ..An emerging concept to combat drug resistance is the idea of targeting host mechanisms that are essential for the propagation of the virus, but have a minimal cellular effect...
  5. pmc Antiviral activity of a small-molecule inhibitor of filovirus infection
    Travis K Warren
    US Army Medical Research Institute of Infectious Diseases, Fort Detrick, Frederick, Maryland, USA
    Antimicrob Agents Chemother 54:2152-9. 2010
    ..Taken together, these results identify a promising antiviral therapeutic candidate for the treatment of filovirus infections...
  6. ncbi request reprint Selective targeting and potent control of tumor growth using an EphA2/CD3-Bispecific single-chain antibody construct
    Scott A Hammond
    MedImmune, Inc, Gaithersburg, Maryland 20878, USA
    Cancer Res 67:3927-35. 2007
    ....
  7. pmc The use of Random Homozygous Gene Perturbation to identify novel host-oriented targets for influenza
    Baoquan Sui
    Functional Genetics, Inc, Gaithersburg, MD 20878, USA
    Virology 387:473-81. 2009
    ..These studies provide further support for a new paradigm to combat viral disease and demonstrate the power of RHGP to identify novel targets and mechanisms...
  8. ncbi request reprint Direct targeting of alphavbeta3 integrin on tumor cells with a monoclonal antibody, Abegrin
    Kathy Mulgrew
    MedImmune, Inc, One MedImmune Way, Gaithersburg, MD 20878, USA
    Mol Cancer Ther 5:3122-9. 2006
    ..In combination with the well-established concept that alphavbeta3 plays a key role in cancer-associated angiogenesis and osteolytic activities, this triad of activity could provide new opportunities for therapeutic targeting of cancer...