Michael S Kinch

Summary

Publications

  1. ncbi Function-first approaches to improve target identification in cancer
    Michael S Kinch
    Functional Genetics Inc, Gaithersburg, MD 20878, USA
    Future Oncol 5:617-23. 2009
  2. ncbi Development of a broad-spectrum antiviral with activity against Ebola virus
    M Javad Aman
    United States Army Medical Research Institute for Infectious Diseases, Fort Detrick, MD 21702, USA
    Antiviral Res 83:245-51. 2009
  3. ncbi Identification of annexin A13 as a regulator of chemotherapy resistance using random homozygous gene perturbation
    Heinz Reiske
    Functional Genetics, Inc, Gaithersburg, Maryland 20878, USA
    Anal Quant Cytol Histol 32:61-9. 2010
  4. ncbi Identification of novel host-oriented targets for Human Immunodeficiency Virus type 1 using Random Homozygous Gene Perturbation
    Hanwen Mao
    Functional Genetics, Inc, Gaithersburg, MD 20878, USA
    Virol J 6:154. 2009
  5. ncbi Selective targeting and potent control of tumor growth using an EphA2/CD3-Bispecific single-chain antibody construct
    Scott A Hammond
    MedImmune, Inc, Gaithersburg, Maryland 20878, USA
    Cancer Res 67:3927-35. 2007
  6. ncbi Antiviral activity of a small-molecule inhibitor of filovirus infection
    Travis K Warren
    US Army Medical Research Institute of Infectious Diseases, Fort Detrick, Frederick, Maryland, USA
    Antimicrob Agents Chemother 54:2152-9. 2010
  7. ncbi The use of Random Homozygous Gene Perturbation to identify novel host-oriented targets for influenza
    Baoquan Sui
    Functional Genetics, Inc, Gaithersburg, MD 20878, USA
    Virology 387:473-81. 2009
  8. ncbi Direct targeting of alphavbeta3 integrin on tumor cells with a monoclonal antibody, Abegrin
    Kathy Mulgrew
    MedImmune, Inc, One MedImmune Way, Gaithersburg, MD 20878, USA
    Mol Cancer Ther 5:3122-9. 2006

Collaborators

Detail Information

Publications8

  1. ncbi Function-first approaches to improve target identification in cancer
    Michael S Kinch
    Functional Genetics Inc, Gaithersburg, MD 20878, USA
    Future Oncol 5:617-23. 2009
    ....
  2. ncbi Development of a broad-spectrum antiviral with activity against Ebola virus
    M Javad Aman
    United States Army Medical Research Institute for Infectious Diseases, Fort Detrick, MD 21702, USA
    Antiviral Res 83:245-51. 2009
    ..These findings suggest FGI-106 may provide an opportunity for targeting viral diseases...
  3. ncbi Identification of annexin A13 as a regulator of chemotherapy resistance using random homozygous gene perturbation
    Heinz Reiske
    Functional Genetics, Inc, Gaithersburg, Maryland 20878, USA
    Anal Quant Cytol Histol 32:61-9. 2010
    ..To utilize a powerful new technology for target discovery, Random Homozygous Gene Perturbation (RHGP), and to identify novel targets that cause tumor cells to become chemoresistant...
  4. ncbi Identification of novel host-oriented targets for Human Immunodeficiency Virus type 1 using Random Homozygous Gene Perturbation
    Hanwen Mao
    Functional Genetics, Inc, Gaithersburg, MD 20878, USA
    Virol J 6:154. 2009
    ..An emerging concept to combat drug resistance is the idea of targeting host mechanisms that are essential for the propagation of the virus, but have a minimal cellular effect...
  5. ncbi Selective targeting and potent control of tumor growth using an EphA2/CD3-Bispecific single-chain antibody construct
    Scott A Hammond
    MedImmune, Inc, Gaithersburg, Maryland 20878, USA
    Cancer Res 67:3927-35. 2007
    ....
  6. ncbi Antiviral activity of a small-molecule inhibitor of filovirus infection
    Travis K Warren
    US Army Medical Research Institute of Infectious Diseases, Fort Detrick, Frederick, Maryland, USA
    Antimicrob Agents Chemother 54:2152-9. 2010
    ..Taken together, these results identify a promising antiviral therapeutic candidate for the treatment of filovirus infections...
  7. ncbi The use of Random Homozygous Gene Perturbation to identify novel host-oriented targets for influenza
    Baoquan Sui
    Functional Genetics, Inc, Gaithersburg, MD 20878, USA
    Virology 387:473-81. 2009
    ..These studies provide further support for a new paradigm to combat viral disease and demonstrate the power of RHGP to identify novel targets and mechanisms...
  8. ncbi Direct targeting of alphavbeta3 integrin on tumor cells with a monoclonal antibody, Abegrin
    Kathy Mulgrew
    MedImmune, Inc, One MedImmune Way, Gaithersburg, MD 20878, USA
    Mol Cancer Ther 5:3122-9. 2006
    ..In combination with the well-established concept that alphavbeta3 plays a key role in cancer-associated angiogenesis and osteolytic activities, this triad of activity could provide new opportunities for therapeutic targeting of cancer...